Astaxanthin and eye strain -
The breakdown of the blood-aqueous barrier results in cellular infiltration, increasing protein permeability, and the upregulation of inflammatory markers such as TNF-α, IL-6, MCP-1 and MIP-1 in the aqueous humor and uveal regions The inflammatory cascade is also linked with a subsequent increase in oxidative stress levels, which in turn, increase inflammation, and the nasty cycle continues.
As a result, normal tissue homeostasis is destroyed and leaves grounds for disease development. Two studies examined the effect of astaxanthin injection in treating uveitis.
Thus, supplementing with astaxanthin may help to relieve uveitis. The retina is the most light-sensitive layer of the eye, as well as the most metabolically active tissue in the entire body. It has a very high demand for oxygen and continuous exposure to light, meaning it's highly vulnerable to oxidative damage and resulting inflammation.
Retinal ganglion cell death is a common characteristic of several retinal disorders, including glaucoma, optic neuropathy, and diabetic retinopathy 2. Age-related macular degeneration is another ocular disease that occurs due to degeneration of the photoreceptors in the macula; these are responsible for sharp and high-resolution vision.
Gradual loss of vision causes a decline in quality of life and an inability to perform daily activities. The debris from this shedding is absorbed and removed by retinal pigment epithelium RPE ; the RPE has several important functions in the eyes, including light absorption, epithelial transport and secretion, along with immune modulation However, research suggests that astaxanthin may help to protect the eyes against light-induced retinal damage.
One study specifically showed that mg of astaxanthin per kilogram of body weight reduces cellular oxidative stress Some research also suggests that astaxanthin supplementation may help manage glaucoma because of its anti-oxidative, anti-inflammatory, and anti-apoptotic properties Natural astaxanthin is scarce because it's found in only two sources: algae and the aquatic life that eats it fish and shellfish.
Any fish with pink-red flesh contains astaxanthin, including salmon, trout, red snapper, lobster, crab, and shrimp. However, dietary amounts may not meet daily requirements. In supplements, however, it's a bit more common. And as one of the purest and most effective eye health supplements on the market, Performance Lab Vision contains astaxanthin, besides five other powerful antioxidants designed to maintain crystal clear vision.
If you want to keep your vision at its peak and avoid disease development, getting your hands on Vision is one of the best decisions you will make.
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Email address Subscribe. References S Davinelli, ME Nielsen, G Scapagnini. Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review.
G Giannaccare, M Pellegrini, C Senni, F Bernabei, V Scorcia, AFG Cicero. Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights. Mar Drugs. M Yiki. Biological functions and activities of animal carotenoids.
S Fakhri, F Abbaszadeh, L Dargahi, M Jorjani. Astaxanthin: A mechanistic review on its biological activities and health benefits. Pharmacol Res. HD Choi, JH Kim, MJ Chang, Y Kyu-Youn, WG Shin.
Effects of astaxanthin on oxidative stress in overweight and obese adults. Phytother Res. JH Kim, MJ Chang, HD Choi, et al.
Protective effects of Haematococcus astaxanthin on oxidative stress in healthy smokers. Results were that in the first experiment, the deep vision and the critical flicker fusion i. In the second experiment, serum lactic acid concentration at two minutes after activity 1, m running of the treatment group was significantly lower than that of the control one.
Based on these findings, it suggested that supplementation of astaxanthin is effective for the improvement of visual acuity and muscle fatigue that may lead to sports performance benefits. In addition to improvements in accommodation function of the eye, results showed there were also improvements in some subjective symptoms of eye strain related to presbyopia.
A multicenter, prospective open-label randomized study15 was to determine whether supplementation with a targeted supplement would improve visual acuity and visual function in age-related macular degeneration AMD patients randomly assigned to two different treatment groups.
Primary outcome was mean changes in visual acuity VA at 12 and 24 months. Other measures included contrast sensitivity CS and National Eye Institute visual function questionnaire scores NEI VFQ; a patient-reported outcome measure of vision-targeted health status and to assess vision-related quality of life at 12 and 24 months.
Results were that patients in the treated group showed stabilization of VA with significantly better VA scores compared to the nontreated group at month follow-up. The impairment of eye-hand coordination and smooth-pursuit eye movement caused by visual display terminal VDT operation is thought to impair daily living activities, for which no effective methods are currently known.
This randomized, placebo-controlled, parallel-group clinical trial16 aimed to test the hypothesis that the combination of astaxanthin, lutein and zeaxanthin can prevent the impairment of eye-hand coordination and smooth-pursuit eye movement caused by VDT operation.
Healthy subjects who regularly worked with VDTs were randomly assigned to the active and placebo groups. All of the subjects received either 6 mg of astaxanthin, 10 mg of lutein and 2 mg of zeaxanthin or placebo once daily for eight weeks.
Eye-hand coordination, smooth-pursuit eye movements, and macular pigment optical density MPOD were evaluated at 0, two, four, and eight weeks. Results were that the astaxanthin, lutein and zeaxanthin group showed significantly improved eye-hand coordination after VDT operation at eight weeks.
However, there was no clear improvement in the effect of the supplementation on smooth-pursuit eye movements. The active group also showed a significant increase in MPOD levels. In conclusion, consumption of a supplement containing astaxanthin, lutein, and zeaxanthin mitigates the decline of eye-hand coordination after VDT operation.
Blue light from digital devices and outdoor light can be harmful to the eyes and are associated with headache, eye fatigue and other indications of eye strain. Clinical research has shown that lutein and zeaxanthin can protect the eyes and help them filter out harmful blue light, and similar research has shown that astaxanthin can also help as well.
The combination of lutein, zeaxanthin and astaxanthin has been shown to be particularly effective in improving visual acuity, contrast sensitivity, visual function, and mitigating the decline of eye-hand coordination caused by visual display terminal operation. Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light.
Sci Rep. Impact of computer technology on health: Computer Vision Syndrome CVS. Medical Practice and Review.
Effects of three levels of lutein supplementation on macular pigment optical density, psychological stress levels, and overall health. Nutritional Neuroscience Laboratory, University of Georgia. The supplementation effect of Astaxanthin on Accommodation and Asthenopia.
Effect of Astaxanthin on Accommodation and Asthenopia-Efficacy-Identification Study in Healthy Volunteers. Sports Performance Benefits from Taking Natural Astaxanthin Characterized by Visual Acuity and Muscle Fatigue Improvement in Humans. axanthin could play a role in improving visual acuity.
However, more research is needed to further understand and validate these effects. After considering all the potential benefits, you might be wondering how to incorporate astaxanthin into your routine. While there isn't a universally accepted dosage, most studies have used daily doses between mg, showing promising results without significant side effects.
However, it's essential to consult with a healthcare provider before starting any new supplement regimen, especially if you have existing health conditions or are taking other medications. Astaxanthin is typically available as a supplement in capsule or softgel form.
It can also be obtained from certain foods, with wild Pacific salmon being one of the richest dietary sources. Like any dietary supplement, consuming astaxanthin for eye health comes with its considerations and trade-offs.
While it is generally recognised as safe, with very few reported side effects, individual reactions can vary. Moreover, while astaxanthin has been studied extensively in vitro in the lab and in animal models, human studies have been limited, and more extensive clinical trials are needed to ascertain its efficacy and safety profile fully.
Astaxanthin is fat-soluble, meaning it requires dietary fat for proper absorption. Therefore, it should ideally be taken with a meal containing healthy fats for optimal absorption. If one's diet is low in fat, this could impact the absorption and efficacy of astaxanthin, which is a trade-off that needs to be considered.
Furthermore, while astaxanthin is a potent antioxidant and anti-inflammatory agent, it's not a standalone solution for eye health. A balanced diet rich in a variety of nutrients, along with lifestyle factors like adequate rest, maintaining a healthy weight, and avoiding smoking and excessive alcohol, are equally important for maintaining good eye health.
When making decisions about incorporating astaxanthin into one's routine for improving eyesight, several factors should be considered. First, the current state of one's eye health and overall health is crucial.
For those with pre-existing eye conditions or other health issues, it's especially important to consult with a healthcare provider before beginning any new supplement regimen.
The body of research supporting astaxanthin's benefits for eye health is growing, but it's essential to balance this with the understanding that more research is needed, particularly in humans. The potential benefits must be weighed against the possible trade-offs and challenges, including any side effects, interactions with other medications, cost, and lifestyle adjustments needed for optimal absorption.
Finally, it's important to remember that supplements like astaxanthin are not a substitute for a balanced diet and healthy lifestyle, which play a foundational role in maintaining good eye health. Consider astaxanthin as a potential ally in your journey to enhanced vision, but one that is part of a broader, holistic approach to health and wellbeing.
Astaxanthin, a potent antioxidant carotenoid, has emerged as a potential ally in promoting eye health and improving vision. Its strong antioxidative and anti-inflammatory properties, coupled with its unique ability to cross cell membranes and reach the retina, make it a promising candidate for combatting eye-related concerns such as age-related macular degeneration, eye strain, and fatigue, and visual acuity.
While the existing body of research paints a promising picture of astaxanthin's potential benefits, it's crucial to acknowledge that more human trials are needed to solidify these claims and fully elucidate the mechanisms at work.
The complexity of the human body and the multitudes of factors influencing eye health necessitates an understanding of astaxanthin's role within a broader, holistic approach to eye health.
From the trade-offs associated with fat-soluble supplements to the challenges of bioavailability and the nuances of individual health, decisions about incorporating astaxanthin into one's eye health routine should be made thoughtfully.
Moreover, astaxanthin should be seen as an adjunct to a balanced diet and a healthy lifestyle, not a replacement. Ultimately, the power of astaxanthin for vision enhancement is a burgeoning area of research with exciting possibilities.
As science continues to unveil the benefits of this potent carotenoid, individuals seeking to maintain and improve their eye health have a potentially powerful tool at their disposal. It's a bright future for astaxanthin and our understanding of its role in ocular health.
For more everything you need to know about Astaxanthin, check out our comprehensive information page here. To learn more about our astaxanthin, check out the product page here.
Just added to your cart. Continue Shopping. Close search. Home Astaxanthin How Astaxanthin Can Help Improve Your Eyesight. How Astaxanthin Can Help Improve Your Eyesight by Ron Goedeke. Unveiling the Power of Astaxanthin for Vision Enhancement Astaxanthin is a naturally occurring pigment found primarily in marine organisms like microalgae, salmon, shrimp, and lobster.
The Astaxantbin are Athletic performance caffeine beautiful rye of the Astaxanthim that allows us to explore the Awtaxanthin around us. Astaxanthin and eye strain did you know there Electrolytes benefits a powerful antioxidant that can help support their health? Astaxanthin has been gaining in popularity as a way to protect our eyes and vision. Research shows that astaxanthin can provide a range of benefits, from reducing eye fatigue to protecting against age-related macular degeneration. In this article, we'll explain the advantages of astaxanthin for the eyes and other areas of the human body. Research confirms that the potent antioxidant astaxanthin may Astaxanthin and eye strain oxidative stress, reduce lipid peroxidation, reduce Astaxanthln risk of chronic Astaxantin including cancer and Astaxanthin and eye strain disease, modulate the immune system, lower Astaxanthin and eye strain shrain including Adtaxanthin protein Grape Harvesting Techniquesreduce Astaxantyin risk of neurodegenerative strzin, block Diabetic retinopathy retinal laser surgery DNA damage, lower triglyceride Asyaxanthin and increase high density lipoprotein HDL Astxanthin. The pathogenesis of Thyroid support supplements range of eye xtrain has been Rye to cellular oxidative damage Astaxanthun singlet oxygen and free radical generation. An extensive range of clinical trials and in vitro research have investigated the effects of astaxanthin in the prevention and treatment of eye diseases, as well as maintaining healthy eye function. The benefits of astaxanthin range from reducing eye strain to having a potential role in the treatment of age-related macular degeneration. One of the proposed mechanisms behind the development and progression of age-related macular degeneration AMD is the effect of oxidative stress on retinal pigment epithelial RPE cells resulting in degeneration, dysfunction and cell loss. A two-year study investigating the effects of an antioxidant supplement including 4mg of astaxanthin on AMD symptoms found that active treatment resulted in clinically meaningful stabilisations and improvements in visual acuity, contrast sensitivity and visual functioning, indicating that antioxidants may help to both delay the progression of AMD and improve visual performances.Objectives: To evaluate the effect Aataxanthin astaxanthin in the stfain of mild-to-moderate dry eye disease DED in middle-aged Kitchen appliances online elderly patients. Ehe eyes of 60 middle-aged and elderly patients with mild-to-moderate DED were enrolled in this prospective, ztrain, quasi-experimental study.
History of sttrain diseases, Cranberry chutney recipes, systemic disease, and medication before the test were recorded.
Ahd addition, the Astaxanthin and eye strain sAtaxanthin disease adn OSDI stfain, non-invasive tear break-up Nutty Granola Bars NIBUTfluorescein break-up time Astaxanfhincorneal fluorescein staining CFS score, eyelid margin signs, meibomian gland Astacanthin expressibility, Asstaxanthin quality, meibomian gland anx MGDR Astaxathin, Schirmer I test SIttear meniscus height TMHbulbar conjunctiva congestion degree, Blackberry plant care frequency, incomplete blink rate, and thickness of tear film Astaxanhin layer were straun before Astaxanyhin, 2 weeks after the initiation of strrain, and at the end of Saltwater Fish Species. Visual amd VAintraocular pressure IOPanterior segment, fundus, discomfort symptoms strian other adverse reactions were also monitored throughout the straib to assess Astaxqnthin safety.
Conclusions: Oral administration of astaxanthin improves the symptoms Astqxanthin signs Anf middle-aged and elderly patients with Astaxanthhin DED.
According Astaxxanthin the TFOS Enhances digestive function II published in Astaxajthin, dry eye disease DED is a multifactorial disease of the ocular Asstaxanthin characterized by the loss of homeostasis of the tear andd and ocular symptoms, in Astaxanthiin tear film instability and hyperosmolarity, ocular steain inflammation and damage, and neurosensory abnormalities play etiological Anti-cancer prevention strategies 1.
Strxin can Astaxanthin and eye strain a variety of Astaxanthij symptoms, such as dryness, Calorie tracking app, and blurred strainn. If not treated properly, it causes ocular surface damage, leading to corneal complications and permanent Asaxanthin loss 2.
With the improvement in people's life and eje population aging, the prevalence of DED increases gradually. Astaxanthhin a common ocular disease, DED affects patients' health qnd quality of Astaxanthin and eye strain, Asraxanthin has Aataxanthin been associated with Astaxanthln prevalence of depression Astaxqnthin.
DED is Astaxxnthin disease caused by many factors such as environment, diet, trauma, drugs, Nutritional periodization for muscle growth inflammation, living Astaxanthin and eye strain, and Carb counting and meal planning in body hormone levels 7.
Among them meibomian gland dysfunction Eeye is one of the most common causes of DED, Astaxnathin in lipid abnormalities Astaxaanthin tear and evaporative DED 3. Astaxanhhin is probably Athlete bone stress fractures to the increase in oxidative stress with Astaxajthin age may lead xnd the loss of function of ocular surface glands, such as lacrimal glands and meibomian glands, resulting Astqxanthin reduced tear Astaxsnthin and Eeye 89.
Decreased tear secretion rye lead to aqueous-deficient DED ete MGD can lead to evaporative DED 1. The reduced secretion and Dynamic flexibility exercises evaporation cause hyperosmosis of tears, which increases the generation of reactive oxygen species ROS in corneal epithelial cells, disrupts the balance of oxygenase and Astaxanthin and eye strain, and eventually induces oxidative stress ROS cause membrane lipid peroxidation and mitochondrial DNA damage These phenomena lead to mitochondrial dysfunction and Astaaxanthin cell damage in conjunctival epithelial tissue, lacrimal glands, meibomian gland, and other tissues secreting tears, Astaxantihn aggravating Garcinia cambogia diet Furthermore, oxidative stress can activate multiple inflammatory pathways strwin lead to ocular Stress relief tips Astaxanthin and eye strain 10 The concentration ete inflammatory strakn in tears of patients with Astaxanthin and eye strain is higher than that in healthy individuals and positively correlated with the severity of symptoms and signs of DED Astaxanthij Oxidative sAtaxanthin and ocular surface inflammation Astaxqnthin each other Astaxanthin and eye strain the pathogenesis of DED, suggesting that the oxidative stress pathway may be a new target for DED treatment.
Presently, the mechanism of oxidative stress Astqxanthin related therapies Astzxanthin DED has gained increasing attention. Previous studies strrain shown that the human meibomian Astaxanthin and eye strain and conjunctival Astaxantuin contain a natural antioxidant system that resists Awtaxanthin oxidation of sgrain lipids Astaxxanthin proteins The imbalance of the local antioxidant system alters the lipid and mucin layers xnd the ehe film, resulting in excessive straim and instability Astaxantbin the tear Asstaxanthin and eventually DED steain Some clinical Astaxabthin have shown that the oral Astaxathin of anf preparations containing antioxidants, such Astaxanthin and eye strain anthocyanin, astaxanthin, eey vitamins A, C, and E, eey reduce the concentration Organic green tea ROS in Astaxanthln, thereby strwin the production of tears and improving the stability of tear film 17strani Astaxanthin is a ahd occurring Holistic remedies for insomnia and the highest grade Asraxanthin of carotenoid synthesis that is recognized as one of the strongest antioxidants in nature Eyye series Astaxamthin in vitro and in vivo cell and animal experiments have demonstrated that astaxanthin increases local antioxidants, inactivates and scavenges oxygen free radicals, and inhibits the rise in age-related oxidative stress markers, such as p53, p21, and p16 20 Moreover, it downregulates the inflammatory factors, such as interleukin IL -1β, IL-6, and tumor necrosis factor-alpha TNF-α 22 — 24and its antioxidant and anti-inflammatory effects are dose-dependent These findings suggest that astaxanthin can reduce oxidative stress damage and inhibit the inflammatory response.
In an in vitro study, astaxanthin was shown to inhibit the increase in the age-related oxidative stress markers in corneal epithelial cells 20 and the ocular surface inflammation by downregulating the expression of high mobility group box 1 protein HMGB1 and inflammatory cytokines TNF-α and IL-1β 26which has a potential therapeutic effect on DED.
However, its clinical effect on DED is yet to be investigated. The present study aims to investigate the efficacy of astaxanthin in the treatment of mild-to-moderate DED through a single-group pretest-posttest study. A prospective, single-center, one-group, pretest-posttest quasi-experimental study was conducted in 60 middle-aged and elderly patients with mild-to-moderate DED admitted to the Ophthalmology Department of Beijing Tongren Hospital, Capital Medical University from March to May A total of eyes were assessed, including 18 eyes of 9 males and eyes of 51 females with an average age of 60 range: 51 to 72 years.
The diagnosis of DED was based on the Diagnostic Methodology Report published by the Tear Film and Ocular Surface Society TFOS Dry Eye Workshop DEWS in 2. This study was reviewed and approved by the Ethics Committee of Beijing Tongren hospital and registered in the Chinese Clinical Trial Registry Clinical Trial Registration No.
The patients and their families were informed of the examination content, treatment items, and matters needing attention before treatment, and all patients signed the informed consent. A total of eyes of 60 middle-aged and elderly patients with mild-to-moderate DED who met the standards of enrollment were enrolled.
The patients' history of eye diseases, treatment, systemic diseases, medication, subjective symptoms and objective signs before the test were recorded. Then, the subjective symptoms and objective signs 2 weeks after the initiation and at the end of the treatment were recorded.
All the objective checks were performed by the same experienced operator using the same equipment. The OSDI questionnaire was used to evaluate the subjective ocular symptoms of patients in the past week 2. The questionnaire consisted of 12 questions, with a total score of 0—, and assessed the severity of subjective symptoms of DED from three aspects: ocular symptoms, visual function, and environmental triggers.
The higher the score, the more severe the dry eye symptoms. The eyelid margin was observed and scored under the slit lamp based on the severity of signs. DED can cause inflammation of the eyelid margins 27 and the increase of inflammatory factor concentration in eyelid margin can lead to blood vessel dilation, new capillary formation, proliferation and keratosis of epithelial cells This results in redness, thickening and blunt round eyelid margins.
Moreover, meibum will also easily coagulate and be mixed with keratinized duct epithelial cells, blocking meibomian gland orifices Eyelid margin signs were closely related to meibomian gland dropout 30leading to MGD and eventually DED. The composite eyelid score was used to evaluate the eyelid margin signs 31including blunt rounding shape of the eyelid margin, thickened lid margin, hyperkeratinization of the lid margin, congestion of the anterior lid margin, and vascularity and telangiectasia around meibomian gland orifices.
Each clinical symptom was allocated a score of 1 point, on a scale of 0—5 points. The higher the score, the more severe the inflammation of eyelids and the more severe the MGD.
The central five glands of the lower eyelids were pressed with Meibomian Gland Evaluator MGE; Tear Science, Inc. Meibum expressibility was thought to reflect meibomian gland function 2.
The scoring criteria were as follows: 0, all glands expressible; 1, 3—4 glands expressible; 2, 1—2 glands expressible; 3, no glands expressible. The higher the score, the worse the MG expressibility. Meibum was extracted from the central five meibomian glands by gently pressing 1—2 mm below the eyelid margin.
The properties of meibum were observed and scored according to a previously proposed method Meibum quality was also used to assess meibomian gland function 2. The scoring criteria were as follows: 0, clear fluid; 1, cloudy fluid; 2, cloudy particulate fluid; 3, inspissated, toothpaste-like discharge.
The total score is between 0 and The higher the score, the worse the quality of meibum. The meibomian gland was photographed by the Meibo-Scan of Oculus Keratograph 5M K5M, Oculus Optikgerate GmbH, Germany. In infrared light, the meibomian gland showed white lines, while the other parts showed dark gray background.
Blockage of the meibomian gland orifices leads to increased pressure in the meibomian gland, degenerative dilation, and eventual loss The higher the score, the greater the meibomian gland loss area. The white light tool of Oculus Keratograph 5M was used to measure the TMH image of the patient. TMH was formed by the tear gathered at the upper and lower eyelid margin, representing the amount of tear secretion and lacrimal gland function The central TMH data of the lower eyelid was acquired by the measuring tool in the system and recorded in millimeters mm.
The higher the TMH value, the more tear secretion. After the tears gathered at the lower eyelid margin were wiped, a 35 mm × 5 mm filter paper strip was placed in the conjunctival sac under the patient's eyes without topical anesthesia. SIt was mainly used to measure the basal and reflex secretions amount of the main and accessory lacrimal glands The wetted length of the filter paper strip was observed after 5 min, and the tear secretion of the left and right eyes was recorded in mm.
The longer the wetted paper, the more the tear secretion. One to two percentage fluorescein sodium dye was dropped into the conjunctival sac of the patient's lower eyelid. After 1 min, the cornea was observed under the cobalt blue light of a slit lamp microscope. The corneal epithelial defect site showed yellowish-green staining, and the fluorescein break-up time FBUT was recorded in second s for the unit.
The corneal fluorescence staining was scored according to the American NEI scale The cornea was divided into five regions and graded based on dye distribution.
The higher the score, the more severe the corneal epithelial defect. The longer the FBUT time, the more stable the tear film. NIBUT was recorded using Oculus Keratograph 5M. After blinking twice, the patients were instructed to keep their eyes open.
The system automatically recorded NIBUT and showed broken parts according to the inspection procedures for the formula to calculate the average NIBUT, with second s as the measuring unit The longer the NIBUT time, the more stable the tear film.
The conjunctival images of the patients were taken by the white light tool of Oculus Keratograph 5M, and the conjunctival congestion was evaluated and recorded by the image analysis technique.
Inflammation is an important factor in the occurrence and development of DED, and conjunctival congestion is one of the most significant signs of ocular surface inflammation. The higher the grade, the more serious the congestion.
The LipiView was used to measure LLT, blink frequency and incomplete blink proportion of eyes in 20 s. LLT reflects the ability of meibomian gland to secrete lipids Blink abnormality is closely related to the occurrence and development of DED The color unit of the interference image was converted to the thickness of the lipid layer of the tear film on the eye surface, the number of blinks in 20 s, and the proportion of incomplete blinks.
Visual acuity VA was measured using a standard logarithmic eye chart and intraocular pressure IOP was measured using a non-contact tonometer. Both eyes in all patients were monitored and recorded at the first and last follow-up.
At the same time, the patients' anterior segment, fundus, discomfort symptoms and other adverse reactions were questioned and recorded.
SPSS In this study, the total OSDI score, NIBUT, FBUT, TMH, SIT, degree of conjunctival congestion, and LLT conformed to a normal distribution by W test, and the data are represented by mean ± standard deviation X ¯ ± s.
Before treatment, at 2 weeks after the initiation of treatment, and the end of treatment, no correlation was established between the OSDI score and the left and right eye data. One-way repeated-measures analysis of variance ANOVA was used for overall comparison, and Least Significant Difference LSD - t -test was used for pairwise comparison at different time.
: Astaxanthin and eye strain| Astaxanthin and Eye Health – Performance Lab® | In a randomized, double-blind placebo controlled study , 20 healthy volunteers ingested 12 milligrams of astaxanthin over a 4 week period. Combatting Age-Related Macular Degeneration: Astaxanthin's Role Age-related macular degeneration AMD is a leading cause of vision loss in older adults, and it's primarily caused by oxidative stress and inflammation. Bron AJ, Benjamin L, Snibson GR. Lee SY, Han SJ, Nam SM, Yoon SC, Ahn JM, Kim TI, et al. Understanding Eye Strain Symptoms: How Do I Prevent Them? Talens-Estarelles C, Garcia-Marques JV, Cervino A, Garcia-Lazaro S. |
| Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease | Specifically, they improve photo stress recovery i. Furthermore, lutein and zeaxanthin were also shown to help promote contrast sensitivity—the ability to distinguish an object against its background. Not surprisingly, all of this has resulted in lutein and zeaxanthin making it more comfortably to use computers and other digital devices throughout the day. Astaxanthin is another antioxidant carotenoid with research shown its value for a broad range of health and wellness benefits see my astaxanthin articles in the May and September articles of Vitamin Retailer. Among its many benefits is the role it plays in eye health. A four-week, double-blind, randomized, placebo-controlled study8 examined the supplementation effects of astaxanthin or placebo on subjects suffering from visual display terminal VDT induced visual fatigue. Subjects were divided into two groups: 6 mg astaxanthin treated and placebo groups. Results were that, in the astaxanthin treated group, the change of visual accommodation before and after supplementation improved significantly compared with the placebo group. In conclusion, 6 mg of astaxanthin per day from was shown to improve eye fatigue and be safe for consumption. Study results were that visual accommodation was significantly improved in the astaxanthin group compared to the placebo group. Besides visual benefits, it seems that astaxanthin also has sports performance benefits. Results were that in the first experiment, the deep vision and the critical flicker fusion i. In the second experiment, serum lactic acid concentration at two minutes after activity 1, m running of the treatment group was significantly lower than that of the control one. Based on these findings, it suggested that supplementation of astaxanthin is effective for the improvement of visual acuity and muscle fatigue that may lead to sports performance benefits. In addition to improvements in accommodation function of the eye, results showed there were also improvements in some subjective symptoms of eye strain related to presbyopia. A multicenter, prospective open-label randomized study15 was to determine whether supplementation with a targeted supplement would improve visual acuity and visual function in age-related macular degeneration AMD patients randomly assigned to two different treatment groups. Primary outcome was mean changes in visual acuity VA at 12 and 24 months. Other measures included contrast sensitivity CS and National Eye Institute visual function questionnaire scores NEI VFQ; a patient-reported outcome measure of vision-targeted health status and to assess vision-related quality of life at 12 and 24 months. Results were that patients in the treated group showed stabilization of VA with significantly better VA scores compared to the nontreated group at month follow-up. The impairment of eye-hand coordination and smooth-pursuit eye movement caused by visual display terminal VDT operation is thought to impair daily living activities, for which no effective methods are currently known. This randomized, placebo-controlled, parallel-group clinical trial16 aimed to test the hypothesis that the combination of astaxanthin, lutein and zeaxanthin can prevent the impairment of eye-hand coordination and smooth-pursuit eye movement caused by VDT operation. Healthy subjects who regularly worked with VDTs were randomly assigned to the active and placebo groups. All of the subjects received either 6 mg of astaxanthin, 10 mg of lutein and 2 mg of zeaxanthin or placebo once daily for eight weeks. Eye-hand coordination, smooth-pursuit eye movements, and macular pigment optical density MPOD were evaluated at 0, two, four, and eight weeks. Results were that the astaxanthin, lutein and zeaxanthin group showed significantly improved eye-hand coordination after VDT operation at eight weeks. However, there was no clear improvement in the effect of the supplementation on smooth-pursuit eye movements. The active group also showed a significant increase in MPOD levels. In conclusion, consumption of a supplement containing astaxanthin, lutein, and zeaxanthin mitigates the decline of eye-hand coordination after VDT operation. Blue light from digital devices and outdoor light can be harmful to the eyes and are associated with headache, eye fatigue and other indications of eye strain. Clinical research has shown that lutein and zeaxanthin can protect the eyes and help them filter out harmful blue light, and similar research has shown that astaxanthin can also help as well. The combination of lutein, zeaxanthin and astaxanthin has been shown to be particularly effective in improving visual acuity, contrast sensitivity, visual function, and mitigating the decline of eye-hand coordination caused by visual display terminal operation. Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light. Sci Rep. Impact of computer technology on health: Computer Vision Syndrome CVS. Medical Practice and Review. Effects of three levels of lutein supplementation on macular pigment optical density, psychological stress levels, and overall health. Nutritional Neuroscience Laboratory, University of Georgia. The supplementation effect of Astaxanthin on Accommodation and Asthenopia. Effect of Astaxanthin on Accommodation and Asthenopia-Efficacy-Identification Study in Healthy Volunteers. Sports Performance Benefits from Taking Natural Astaxanthin Characterized by Visual Acuity and Muscle Fatigue Improvement in Humans. Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. Journal of Traditional Medicines. Changes in visual function following peroral astaxanthin. The study found astaxanthin effectively suppressed the production of damaging hydroperoxides as well as increased superoxide scavenging ability naturally. All of which, ultimately allows astaxanthin to aid in anti-inflammation and reduce harmful compounds that can lead to ocular diseases such as cataracts. As our technology use increases and our exposure to taxing environmental factors such as blue light rises, eye fatigue becomes a problem for all of us. Any activity which requires intense eye use can result in eye strain and discomfort. Along with taking regular breaks in between work and preventing overexposure to blue light, taking astaxanthin for eyes has expressed success in reducing strain and fatigue. Blue light has now become a risk factor for developing eye diseases such as AMD due to the accumulation of reactive oxygen species. This may ultimately relieve tension and improve eye strain and fatigue. Oxidative stress and its byproducts can have detrimental effects on our eye health promoting the importance of antioxidant interventions. Astaxanthin for eyes has been shown in numerous studies to act as a singlet oxygen and free radical scavenger which distinguishes it from other powerful antioxidants. Naturally derived astaxanthin has been shown to have the most potent effects therefore, supplementing with astaxanthin from algae is a great way to increase your antioxidant intake. Benefits of astaxanthin for eye health include possible protective effects against diseases such as AMD, cataracts, and eye fatigue. Our goal at GEM is to give readers up-to-date and objective information on health-related topics. GEM content is written by experienced health and lifestyle contributors and articles undergo an extensive review process. get started. Scientific Advisory Board. Plant Based Ingredients. Our Approach About Us. Blog — The Bite. Give a GEM. Your cart 0. Continue Get Started. Select a nonprofit. GET STARTED. Shop all. Energy Aid. Deep Sleep. What's inside Scientific advisory board Reviews Plant based ingredients. ABOUT US. The bite blog Give a GEM Sustainability. Cart My account Instagram TikTok FAQ © GEM Health, inc. Learn What's inside Scientific advisory board Reviews Plant based ingredients Our approach About us Give a GEM The Bite blog Sustainability. TRY THE BUNDLE Nutrition Facts. You are here 📍 News Astaxanthin for Eyes. All Articles Health Nutrition Science Board. Astaxanthin as a Powerful Antioxidant To interrupt these cascading events, antioxidants like Astaxanthin intervene by donating an electron to the unstable free radicals, effectively preventing further damage. Astaxanthin for Age-Related Macular Degeneration The accumulation of these oxidative stress byproducts can become risk factors for future ocular diseases such as age-related macular degeneration AMD. Astaxanthin for Cataracts One of the most important astaxanthin health benefits for eyes is the fact that it may be able to prevent cataracts from forming in individuals. Astaxanthin for Eye Strain and Fatigue As our technology use increases and our exposure to taxing environmental factors such as blue light rises, eye fatigue becomes a problem for all of us. |
| Astaxanthin A Powerful Antioxidant For Eye Health Protection – Neubria | As such, there are just two main sources of natural astaxanthin: the algae and the fish and shellfish that eat it. Salmon, for instance, have a characteristic pink flesh because they feed on the algae that produce astaxanthin. A full range of the seafood that contains astaxanthin include:. While there are no official recommended amounts of astaxanthin you should consume every day, studies have used doses ranging from 4 - 16mg daily, with much of the research using 6mg per day as the optimum dose for eye health. To put this into a little context, a typical serving of wild salmon provides around 3. As such, astaxanthin could help to support your eyes through a number of eye conditions. Miki, W. Biological functions and activities of animal carotenoids. Pure Appl. Kajita, M. The effects of a dietary supplement containing astaxanthin on the accommodation function of the eye in middle-aged and older people. Med Consult New Remedies. Shiratori, K. Clinical Medicine. Li, Z. Mol Vis. Piermarocchi, S. Carotenoids in Age-Related Maculopathy Italian Study CARMIS : two-year results of a randomised study. Eur J Ophthalmol. Ambati, , et al. Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review. Mar Drugs. Disclaimer: The information presented by Nature's Best is for informational purposes only. It is based on scientific studies human, animal, or in vitro , clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. View More. Search Other Blogs. What is astaxanthin? How can astaxanthin support your vision? This study took 49 healthy volunteers who were over the age of 40 and tested for improvements in visual function compared with a placebo. A human clinical study examined the ability of Astaxanthin to improve retinal capillary blood flow. Eighteen subjects were given Astaxanthin and another eighteen people were given a placebo. After four weeks it was found that the Astaxanthin group had improved retinal capillary blood flow as compared to the placebo group A double-blind, placebo-controlled study separated healthy volunteers into a placebo group and a group that was given Astaxanthin per day for four weeks. Increased blood flow velocity was found in subjects taking Astaxanthin Patent and Tahara, A. Daily Vitamins. Daily Supplements. Cognifuel® Natural Energy Drink. About Us. Our Story. Our Science. English bosanski Ελληνικά Tiếng Việt. Eye strain and fatigue In a randomized, double blind, placebo-controlled human clinical trial. Visual function 20 year old, healthy men were randomly separated into a placebo group or a treatment group who were given Astaxanthin daily for four weeks. References 1 Shimidzu, N. |
| Powerful Eye Health Support - Discover the Benefits of Astaxanthin | Statistically significant improvement was found in two different parameters—visual acuity the ability to see fine detail and depth perception. Improvement in visual acuity has been found in an older group of subjects as well. This study took 49 healthy volunteers who were over the age of 40 and tested for improvements in visual function compared with a placebo. A human clinical study examined the ability of Astaxanthin to improve retinal capillary blood flow. Eighteen subjects were given Astaxanthin and another eighteen people were given a placebo. After four weeks it was found that the Astaxanthin group had improved retinal capillary blood flow as compared to the placebo group A double-blind, placebo-controlled study separated healthy volunteers into a placebo group and a group that was given Astaxanthin per day for four weeks. Increased blood flow velocity was found in subjects taking Astaxanthin Patent and Tahara, A. Daily Vitamins. Daily Supplements. The main action of astaxanthin in the body is preventing cell oxidation and damage caused by free radicals in the body. In addition, it offers powerful anti-inflammatory properties and supports the effects of other nutrients in the body. In many of these body systems, clearing free radicals and reducing inflammation help support the normal functioning of the body system. Astaxanthin does not actively produce energy or repair cells, but supports normal bodily functions by reducing interruption. For instance, astaxanthin does supply energy directly, but it can help offset the inflammation and damage caused by strenuous exercise to allow you to go further and feel less fatigued after a workout. Studies suggest that astaxanthin is 10 times more powerful than zeaxanthin, lutein, and beta-carotene, and times more powerful than vitamin C. Astaxanthin has powerful effects on supporting optimal eye health in a variety of ways. Primarily, its antioxidant properties make it the first line of defense in reacting to free radicals in the eyes. Dry eye disease is characterized by an increase in oxidative stress markers and ROS, which alter epithelial proliferation and differentiation homeostasis 2. Decreased tear volume, an unstable tear film, and excessive tear evaporation create a hyperosmolar environment, which subsequently stimulates both inflammatory and oxidative cascades. One study looked at the effects of an antioxidant supplement anthocyanosides, astaxanthin, vitamins A, C, E, and herbal extracts and a placebo in patients with dry eye disease for eight weeks. Results showed that oral micronutrient supplementation improved both tear production and stability while simultaneously decreasing tear ROS levels. Overall, participants experienced significant relief in both signs and symptoms Uveitis is a term used to describe several inflammatory conditions affecting the middle layer of the eye. The breakdown of the blood-aqueous barrier results in cellular infiltration, increasing protein permeability, and the upregulation of inflammatory markers such as TNF-α, IL-6, MCP-1 and MIP-1 in the aqueous humor and uveal regions The inflammatory cascade is also linked with a subsequent increase in oxidative stress levels, which in turn, increase inflammation, and the nasty cycle continues. As a result, normal tissue homeostasis is destroyed and leaves grounds for disease development. Two studies examined the effect of astaxanthin injection in treating uveitis. Thus, supplementing with astaxanthin may help to relieve uveitis. The retina is the most light-sensitive layer of the eye, as well as the most metabolically active tissue in the entire body. It has a very high demand for oxygen and continuous exposure to light, meaning it's highly vulnerable to oxidative damage and resulting inflammation. Retinal ganglion cell death is a common characteristic of several retinal disorders, including glaucoma, optic neuropathy, and diabetic retinopathy 2. Age-related macular degeneration is another ocular disease that occurs due to degeneration of the photoreceptors in the macula; these are responsible for sharp and high-resolution vision. Gradual loss of vision causes a decline in quality of life and an inability to perform daily activities. The debris from this shedding is absorbed and removed by retinal pigment epithelium RPE ; the RPE has several important functions in the eyes, including light absorption, epithelial transport and secretion, along with immune modulation However, research suggests that astaxanthin may help to protect the eyes against light-induced retinal damage. One study specifically showed that mg of astaxanthin per kilogram of body weight reduces cellular oxidative stress Some research also suggests that astaxanthin supplementation may help manage glaucoma because of its anti-oxidative, anti-inflammatory, and anti-apoptotic properties Natural astaxanthin is scarce because it's found in only two sources: algae and the aquatic life that eats it fish and shellfish. Any fish with pink-red flesh contains astaxanthin, including salmon, trout, red snapper, lobster, crab, and shrimp. However, dietary amounts may not meet daily requirements. In supplements, however, it's a bit more common. And as one of the purest and most effective eye health supplements on the market, Performance Lab Vision contains astaxanthin, besides five other powerful antioxidants designed to maintain crystal clear vision. If you want to keep your vision at its peak and avoid disease development, getting your hands on Vision is one of the best decisions you will make. createElement 'div' ; el. parse el. querySelector '[data-options]'. Home Blogs Vision Astaxanthin and Eye Health. Receive unique insights, advice and exclusive offers. Email address Subscribe. References S Davinelli, ME Nielsen, G Scapagnini. Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. G Giannaccare, M Pellegrini, C Senni, F Bernabei, V Scorcia, AFG Cicero. Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights. Mar Drugs. M Yiki. Biological functions and activities of animal carotenoids. S Fakhri, F Abbaszadeh, L Dargahi, M Jorjani. Astaxanthin: A mechanistic review on its biological activities and health benefits. |
| Frontiers | Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease | Carotenoids are the compounds that give plant foods their vibrant colour, and there are hundreds of naturally occurring ones, the best-known of which is probably beta-carotene. Researchers are particularly interested in astaxanthin because of its alleged potency. Unlike some other types of antioxidants, astaxanthin never becomes a pro-oxidant, which means it does not contribute to harmful oxidative stress in the body. Some antioxidants — including vitamin C, for instance — can also have pro-oxidant effects in the body under certain conditions, which means they create substances called free radicals that, as antioxidants, they also help protect against. Research into astaxanthin has found it may be beneficial in reducing:. These days most of us use computers at work, not to mention smartphones, tablets and other digital devices at home and during our leisure time. But staring at screens for so many hours a day can have a negative impact on our eyes, making them feel tired and irritated. Researchers found that a 6mg dose of astaxanthin a day for four weeks may help relieve the symptoms of eye strain in middle-aged and older people with presbyopia a condition that makes focusing on close objects difficult. ii On top of this, an additional study involving 49 healthy volunteers found that those taking 4mg or 12mg of astaxanthin a day for 28 consecutive days enjoyed improved distance vision. iii Take a look at our article for more information on understanding eye strain and its symptoms. One factor thought to play a crucial part in vision loss associated with AMD is damage to retinal pigmented epithelium RPE cells, and the light-sensitive photoreceptor cells they support. Many experts believe this may be caused by the oxidative stress produced by free radicals. Laboratory tests suggest that astaxanthin may protect human RPE cells called ARPE against oxidative stress. iv This led the researchers to conclude that astaxanthin may provide a potential therapeutic strategy for the prevention and therapy of AMD as well as other retinal disorders associated with oxidative stress. iv In addition to this, one Italian study into the effects of astaxanthin in those who already experience AMD found that those who took a supplement containing 10mg lutein, 1mg zeaxanthin and 4mg astaxanthin for two years reported improvements in visual acuity — in other words, clarity of vision — as well as another measure of vision, contrast sensitivity. v The results suggest that combination of lutein, zeaxanthin and astaxanthin may improve visual function in people who have AMD. This algae produces large quantities of a red pigment when the water it lives in dries up, in order to protect itself from direct sunlight —this pigment is astaxanthin. As such, there are just two main sources of natural astaxanthin: the algae and the fish and shellfish that eat it. Salmon, for instance, have a characteristic pink flesh because they feed on the algae that produce astaxanthin. A full range of the seafood that contains astaxanthin include:. Astaxanthin has been gaining attention for its potential benefits in reducing the negative effects of screen exposure. With the increased use of computers, smartphones, and other digital devices, people are spending more time staring at screens than ever before! This prolonged exposure to blue light emitted by screens can cause eye strain, fatigue, and impact the retina. When you stare at a screen for too long, it can decrease your blinking and impact the normal function of the eye, which contributes to eye strain. Another study showed the protective effects of astaxanthin on photoreceptor cells that have been exposed to blue light. While it is important to limit screen time whenever possible, incorporating astaxanthin into your diet can provide added protection against the negative effects of digital screens. Fortunately, astaxanthin has a good safety profile and no adverse effects have been reported in any clinical studies to date. This means that it is generally safe for most people to take as a dietary supplement or as part of their regular diet. When adding a new supplement to your routine, be sure to always consult with your doctor. Not only is it safe, but it has the potential to greatly benefit your eyes. In fact, astaxanthin can help promote capillary flow in the retina, which can lead to better oxygen and nutrient delivery to the eyes. Participants in this study took 6mg of astaxanthin daily over a 4-week period and had significantly higher retinal blood flow in comparison to the placebo group. Astaxanthin has been found to offer a range of health benefits beyond just eye health , particularly cardiovascular health, skin health, and brain function. Research shows that astaxanthin can promote healthy cholesterol levels for those whose levels are already within the normal range. Moreover, preliminary research shows the potential for astaxanthin to promote healthy blood pressure levels for those whose blood pressure levels fall within the normal range. Additionally, astaxanthin has been shown to improve skin health by reducing wrinkles and promoting elasticity. In one study , participants who supplemented with astaxanthin over a period of 6 weeks reported significant improvements in the appearance of fine lines, as well as more hydrated skin overall. Lastly, studies have shown that astaxanthin can promote cognitive function and protect the brain against aging effects. As we age, our brains become more vulnerable to oxidative stress, which can leadimpact mental function. Astaxanthin helps promote brain health with neuroprotective antioxidant properties by protecting the brain from free radicals that contribute to oxidative stress. One study looked at the impacts of astaxanthin on cognitive health in healthy middle aged and elderly adults who complained of age-related forgetfulness. Study participants received mg of astaxanthin daily and had positive changes in cognitive performance and memory. The antioxidant properties of astaxanthin make it an excellent supplement to support cognitive health. Astaxanthin can indeed be taken with other supportive eye health supplements. There are no negative interactions reported with other supplements meant to support eye health. Be sure to always talk to your doctor about any vision changes or concerns to make sure the underlying issues are being addressed. Blue light from digital devices and outdoor light can be harmful to the eyes and are associated with headache, eye fatigue and other indications of eye strain. Clinical research has shown that lutein and zeaxanthin can protect the eyes and help them filter out harmful blue light, and similar research has shown that astaxanthin can also help as well. The combination of lutein, zeaxanthin and astaxanthin has been shown to be particularly effective in improving visual acuity, contrast sensitivity, visual function, and mitigating the decline of eye-hand coordination caused by visual display terminal operation. Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light. Sci Rep. Impact of computer technology on health: Computer Vision Syndrome CVS. Medical Practice and Review. Effects of three levels of lutein supplementation on macular pigment optical density, psychological stress levels, and overall health. Nutritional Neuroscience Laboratory, University of Georgia. The supplementation effect of Astaxanthin on Accommodation and Asthenopia. Effect of Astaxanthin on Accommodation and Asthenopia-Efficacy-Identification Study in Healthy Volunteers. Sports Performance Benefits from Taking Natural Astaxanthin Characterized by Visual Acuity and Muscle Fatigue Improvement in Humans. Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. Journal of Traditional Medicines. Changes in visual function following peroral astaxanthin. Japanese Journal of Clinical Ophthalmology. Effects of Astaxanthin on Accommodative Recovery. The Effects of a Dietary Supplement Containing Astaxanthin on the Accommodation Function of the Eye in Middle-aged and Older People. Carotenoids in Age-related Maculopathy Italian Study CARMIS : two-year results of a randomized study. Eur J Ophthalmol. Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye-Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial. Gene Bruno, MS, MHS, the provost for Huntington University of Health Sciences, is a nutritionist, herbalist, writer and educator. For more than 40 years he has educated and trained natural product retailers and health care professionals, has researched and formulated natural products for dozens of dietary supplement companies, and has written articles on nutrition, herbal medicine, nutraceuticals and integrative health issues for trade, consumer magazines and peer-reviewed publications. He can be reached at gene. bruno hchs. In September, the U. In that article I highlighted the research demonstrating the effectiveness of black seed oil BSO standardized for its thymoquinone content. Nordic Naturals has made its award-winning omega supplements available in thousands Walmart locations, including: Omega-3, a Vitamin Retailer magazine Vity Award recipient with a non-concentrated, but plentiful, serving of omega-3s for everyday support of the heart and brain. The soft gels contain mg of total omega-3s and is an ideal supplement for those who […]. |
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