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Gastric ulcer therapy -

Depending on which test is used, you may need to discontinue the medication for a period of time because antacids can lead to false-negative results. Your doctor may use a scope to examine your upper digestive system endoscopy.

During endoscopy, your doctor passes a hollow tube equipped with a lens endoscope down your throat and into your esophagus, stomach and small intestine. Using the endoscope, your doctor looks for ulcers. If your doctor detects an ulcer, a small tissue sample biopsy may be removed for examination in a lab.

A biopsy can also identify whether H. pylori is in your stomach lining. Your doctor is more likely to recommend endoscopy if you are older, have signs of bleeding, or have experienced recent weight loss or difficulty eating and swallowing.

If the endoscopy shows an ulcer in your stomach, a follow-up endoscopy should be performed after treatment to show that it has healed, even if your symptoms improve.

Our caring team of Mayo Clinic experts can help you with your peptic ulcer-related health concerns Start Here. Treatment for peptic ulcers depends on the cause. Usually treatment will involve killing the H. pylori bacterium if present, eliminating or reducing use of NSAIDs if possible, and helping your ulcer to heal with medication.

Antibiotic medications to kill H. pylori is found in your digestive tract, your doctor may recommend a combination of antibiotics to kill the bacterium.

These may include amoxicillin Amoxil , clarithromycin Biaxin , metronidazole Flagyl , tinidazole Tindamax , tetracycline and levofloxacin. The antibiotics used will be determined by where you live and current antibiotic resistance rates.

You'll likely need to take antibiotics for two weeks, as well as additional medications to reduce stomach acid, including a proton pump inhibitor and possibly bismuth subsalicylate Pepto-Bismol.

Medications that block acid production and promote healing. Proton pump inhibitors — also called PPIs — reduce stomach acid by blocking the action of the parts of cells that produce acid. These drugs include the prescription and over-the-counter medications omeprazole Prilosec , lansoprazole Prevacid , rabeprazole Aciphex , esomeprazole Nexium and pantoprazole Protonix.

Long-term use of proton pump inhibitors, particularly at high doses, may increase your risk of hip, wrist and spine fracture.

Ask your doctor whether a calcium supplement may reduce this risk. Medications to reduce acid production. Acid blockers — also called histamine H-2 blockers — reduce the amount of stomach acid released into your digestive tract, which relieves ulcer pain and encourages healing.

Available by prescription or over the counter, acid blockers include the medications famotidine Pepcid AC , cimetidine Tagamet HB and nizatidine Axid AR. Antacids that neutralize stomach acid. Your doctor may include an antacid in your drug regimen.

Antacids neutralize existing stomach acid and can provide rapid pain relief. Side effects can include constipation or diarrhea, depending on the main ingredients. Medications that protect the lining of your stomach and small intestine. In some cases, your doctor may prescribe medications called cytoprotective agents that help protect the tissues that line your stomach and small intestine.

Treatment for peptic ulcers is often successful, leading to ulcer healing. But if your symptoms are severe or if they continue despite treatment, your doctor may recommend endoscopy to rule out other possible causes for your symptoms.

If an ulcer is detected during endoscopy, your doctor may recommend another endoscopy after your treatment to make sure your ulcer has healed. Ask your doctor whether you should undergo follow-up tests after your treatment. Peptic ulcers that don't heal with treatment are called refractory ulcers.

There are many reasons why an ulcer may fail to heal, including:. Treatment for refractory ulcers generally involves eliminating factors that may interfere with healing, along with using different antibiotics. If you have a serious complication from an ulcer, such as acute bleeding or a perforation, you may require surgery.

However, surgery is needed far less often now than previously because of the many effective medications available.

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Products containing bismuth may help with symptoms of a peptic ulcer. There is also some evidence that zinc can help heal ulcers. Mastic powder, the product of a type of evergreen shrub, may also help improve symptoms and speed healing of peptic ulcers.

While certain over-the-counter and alternative medications may be helpful, evidence on effectiveness is lacking. Therefore they are not recommended as the primary treatment for peptic ulcers.

Make an appointment with your regular doctor if you have signs or symptoms that worry you. Your doctor may refer you to a specialist in the digestive system gastroenterologist.

It's a good idea to be well prepared for your appointment. Here's some information to help you get ready, and what you can expect from your doctor. In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask other questions during your appointment.

Your doctor is likely to ask you a number of questions. Being ready to answer them may reserve time to go over points you want to cover. Your doctor may ask:.

While you're waiting to see your doctor, avoiding tobacco, alcohol, spicy foods and stress may help lessen your discomfort. Peptic ulcer care at Mayo Clinic. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.

Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. This content does not have an English version. This content does not have an Arabic version. Diagnosis Upper endoscopy Enlarge image Close. Upper endoscopy An upper endoscopy procedure involves inserting a long, flexible tube called an endoscope down your throat and into your esophagus.

Care at Mayo Clinic Our caring team of Mayo Clinic experts can help you with your peptic ulcer-related health concerns Start Here. More Information Peptic ulcer care at Mayo Clinic Needle biopsy Upper endoscopy X-ray Show more related information.

More Information Peptic ulcer care at Mayo Clinic Upper endoscopy. Request an appointment. Email address. Thank you for subscribing Your in-depth digestive health guide will be in your inbox shortly.

Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Call your doctor right away if you have sharp stomach pain, you're sweating a lot or feeling confused, or your stomach feels hard to the touch.

These could be signs of a serious ulcer complication that needs immediate medical help. Normally, the lining of the stomach and small intestines can protect itself against strong stomach acids.

But if the lining breaks down, the result may be:. Most ulcers occur in the first, inner surface, layer of the inner lining. A hole in the stomach or duodenum is called a perforation. This is a medical emergency. The most common cause of ulcers is infection of the stomach by bacteria called Helicobacter pylori H pylori.

Most people with peptic ulcers have these bacteria living in their digestive tract. Yet, many people who have these bacteria in their stomach do not develop an ulcer. A rare condition, called Zollinger-Ellison syndrome , causes the stomach to produce too much acid, leading to stomach and duodenal ulcers.

Small ulcers may not cause any symptoms and may heal without treatment. Some ulcers can cause serious bleeding. Abdominal pain often in the upper mid-abdomen is a common symptom. The pain can differ from person to person.

Some people have no pain. To detect an ulcer, you may need a test called an upper endoscopy esophagogastroduodenoscopy or EGD.

Testing for H pylori is also needed. This may be done by biopsy of the stomach during endoscopy, with a stool test, or by a urea breath test. Sometimes, you may need a test called an upper GI series. A series of x-rays are taken after you drink a thick substance that contains barium.

This does not require sedation. Your health care provider will recommend medicines to heal your ulcer and prevent a relapse. The medicines will:. Take all of your medicines as you have been told. Other changes in your lifestyle can also help. If you have a peptic ulcer with an H pylori infection, the standard treatment uses different combinations of the following medicines for 7 to 14 days:.

Your provider may also prescribe this type of medicine regularly if you continue taking aspirin or NSAIDs for other health conditions. If a peptic ulcer bleeds a lot, an EGD may be needed to stop the bleeding. Methods used to stop the bleeding include:.

Peptic ulcers tend to come back if untreated. There is a good chance that the H pylori infection will be cured if you take your medicines and follow your provider's advice. You will be much less likely to get another ulcer. Avoid aspirin, ibuprofen, naproxen, and other NSAIDs.

Try acetaminophen instead. If you must take such medicines, talk to your provider first. Your provider may:. Chan FKL, Lau JYW. Peptic ulcer disease.

In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. Philadelphia, PA: Elsevier; chap Cover TL, Blaser MJ. Helicobacter pylori and other gastric Helicobacter species.

In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Lanas A, Chan FKL. PMID: pubmed. Reviewed by: Michael M.

Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A. Editorial team. Share Facebook Twitter Linkedin Email Home Health Library.

Peptic ulcer Ulcer - peptic; Ulcer - duodenal; Ulcer - gastric; Duodenal ulcer; Gastric ulcer; Dyspepsia - ulcers; Bleeding ulcer; Gastrointestinal bleeding - peptic ulcer; Gastrointestinal hemorrhage - peptic ulcer; G. Causes Normally, the lining of the stomach and small intestines can protect itself against strong stomach acids.

But if the lining breaks down, the result may be: Swollen and inflamed tissue gastritis An ulcer Most ulcers occur in the first, inner surface, layer of the inner lining. The following factors raise your risk for peptic ulcers: Drinking too much alcohol Regular use of aspirin, ibuprofen, naproxen, or other nonsteroidal anti-inflammatory drugs NSAIDs Smoking cigarettes or chewing tobacco Being very ill, such as being on a breathing machine Radiation treatments Stress A rare condition, called Zollinger-Ellison syndrome , causes the stomach to produce too much acid, leading to stomach and duodenal ulcers.

Symptoms Small ulcers may not cause any symptoms and may heal without treatment. Pain occurs: In the upper abdomen At night and wakes you up When you feel an empty stomach, often 1 to 3 hours after a meal Other symptoms include: Feeling of fullness and problems drinking as much fluid as usual Nausea Vomiting Bloody or dark, tarry stools Chest pain Fatigue Vomiting, possibly bloody Weight loss Ongoing heartburn.

Exams and Tests To detect an ulcer, you may need a test called an upper endoscopy esophagogastroduodenoscopy or EGD. This is a test to check the lining of the esophagus food pipe , stomach, and first part of the small intestine.

It is done with a small camera flexible endoscope that is inserted down the throat. This test most often requires sedation given through a vein. In some cases, a smaller endoscope may be used that is passed into the stomach through the nose.

EGD is done on most people when peptic ulcers are suspected or when you have: Low blood count anemia Trouble swallowing Bloody vomit Bloody or dark and tarry-looking stools Lost weight without trying Other findings that raise a concern for cancer in the stomach Testing for H pylori is also needed.

Other tests you may have include: Hemoglobin blood test to check for anemia Stool occult blood test to test for blood in your stool Sometimes, you may need a test called an upper GI series.

Treatment Your health care provider will recommend medicines to heal your ulcer and prevent a relapse.

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You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Your in-depth digestive health guide will be in your inbox shortly. You will also receive emails from Mayo Clinic on the latest health news, research, and care.

Peptic ulcers occur when acid in the digestive tract eats away at the inner surface of the stomach or small intestine. The acid can create a painful open sore that may bleed. Your digestive tract is coated with a mucous layer that normally protects against acid.

But if the amount of acid is increased or the amount of mucus is decreased, you could develop an ulcer. A bacterium. Helicobacter pylori bacteria commonly live in the mucous layer that covers and protects tissues that line the stomach and small intestine.

Often, the H. pylori bacterium causes no problems, but it can cause inflammation of the stomach's inner layer, producing an ulcer. It's not clear how H. pylori infection spreads. It may be transmitted from person to person by close contact, such as kissing. People may also contract H.

pylori through food and water. In addition to having risks related to taking NSAIDsyou may have an increased risk of peptic ulcers if you:. Alone, these factors do not cause ulcers, but they can make ulcers worse and more difficult to heal.

You may reduce your risk of peptic ulcer if you follow the same strategies recommended as home remedies to treat ulcers. It also may be helpful to:. Protect yourself from infections. It's not clear just how H. pylori spreads, but there's some evidence that it could be transmitted from person to person or through food and water.

You can take steps to protect yourself from infections, such as H. pylori, by frequently washing your hands with soap and water and by eating foods that have been cooked completely.

Use caution with pain relievers. If you regularly use pain relievers that increase your risk of peptic ulcer, take steps to reduce your risk of stomach problems. For instance, take your medication with meals. Work with your doctor to find the lowest dose possible that still gives you pain relief.

Avoid drinking alcohol when taking your medication, since the two can combine to increase your risk of stomach upset. If you need an NSAIDyou may need to also take additional medications such as an antacid, a proton pump inhibitor, an acid blocker or cytoprotective agent.

A class of NSAIDs called COX-2 inhibitors may be less likely to cause peptic ulcers, but may increase the risk of heart attack. Peptic ulcer care at Mayo Clinic. Mayo Clinic does not endorse companies or products.

Advertising revenue supports our not-for-profit mission. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press.

This content does not have an English version. This content does not have an Arabic version. Overview Ulcers Enlarge image Close. Ulcers A peptic ulcer is a sore on the lining of your stomach, small intestine or esophagus.

Request an appointment. Email address. Thank you for subscribing Your in-depth digestive health guide will be in your inbox shortly. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry.

By Mayo Clinic Staff. Show references Kellerman RD, et al. Gastritis and peptic ulcer disease. In: Conn's Current Therapy Elsevier; Accessed July 8, Peptic ulcer disease. American College of Gastroenterology. Peptic ulcers stomach ulcers. National Institute of Diabetes and Digestive and Kidney Diseases.

Feldman M, et al. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. Saunders Elsevier; Nehra AK, et al. Proton pump inhibitors: Review of emerging concerns.

Mayo Clinic Proceedings. Peptic ulcer disease adult. Mayo Clinic; Peptic ulcers. Natural Medicines. Accessed July 21, Brown AY. AllScripts EPSi. Rochester, Minn. June 23, Helicobacter pylori and cancer.

National Cancer Institute. Accessed July 27, Related Ulcers. Associated Procedures Needle biopsy Upper endoscopy X-ray.

: Gastric ulcer therapy

Ulcer symptoms	The discovery of this micro-organism in revolutionised many aspects of gastroenterology, including the treatment of stomach ulcers. Accessed July 21, American College of Gastroenterology. Peptic ulcers stomach ulcers. Your in-depth digestive health guide will be in your inbox shortly. There are two types of peptic ulcers:.
What if an ulcer doesn’t heal or comes back after treatment?	org is powered by. Explore careers. In fact, Dr. If you are a Mayo Clinic patient, this could include protected health information. The main complications include: bleeding at the site of the ulcer the stomach lining at the site of the ulcer splitting open perforation the ulcer blocking the movement of food through the digestive system gastric obstruction Read more about the complications of stomach ulcers. In fact, several animal studies show that cabbage juice is effective at treating and preventing a wide range of digestive ulcers, including those affecting the stomach 6 , 7 , 8.
Antibiotics	bleed - peptic ulcer; H. Medically reviewed by Natalie Olsen, R. They may recommend an alternative, such as acetaminophen. Peptic ulcers occur when acid in the digestive tract eats away at the inner surface of the stomach or small intestine. pylori, by frequently washing your hands with soap and water and by eating foods that have been cooked completely. Your provider may also prescribe this type of medicine regularly if you continue taking aspirin or NSAIDs for other health conditions.

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How To Treat Peptic Ulcer -Health Focus-