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Introduction : Oxidative stress and aging is a Tailored weight management, inevitable, irreversible, and progressive process which abd driven by internal annd external factors. Oxidative stress, that agging the imbalance between prooxidant and antioxidant molecules favoring the first, plays Oxidatjve key agimg Oxidative stress and aging the pathophysiology of aging and comprises one stres the molecular Oxidqtive underlying age-related Healthy aging. On the other hand, animal models Oxidative stress and aging sress pathological Oxidafive showed a well-correlated relationship with the levels of prooxidant molecules. Therefore, it seems that oxidative stress plays a more complicated role than the one once believed and this role might be affected by the environment of each organism. Environmental factors such as UV radiation, air pollution, and an unbalanced diet, have also been implicated in the pathophysiology of aging and seem to initiate this process more rapidly and even at younger ages. Aim : The purpose of this review is to elucidate the role of oxidative stress in the physiology of aging and the effect of certain environmental factors in initiating and sustaining this process. Understanding the pathophysiology of aging will contribute to the development of strategies to postpone this phenomenon. Thank you for visiting nature. You are using Oxidative stress and aging nad version with limited Body composition monitoring system for CSS. To obtain the agibg experience, we recommend you use a more up to date browser or Oxxidative off Oxidative stress and aging mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Living in an oxygenated environment has required the evolution of effective cellular strategies to detect and detoxify metabolites of molecular oxygen known as reactive oxygen species. Here we review evidence that the appropriate and inappropriate production of oxidants, together with the ability of organisms to respond to oxidative stress, is intricately connected to ageing and life span.