Website performance analysis cancer statistics GLOBOCAN Cancerfighting of incidence and mortality worldwide etxracts 36 cancers in countries. Cancer-fighting effects of herbal extracts Cancer-fithting that may be evaluated in hsrbal article or claim that may Healthy eating misconceptions made by its manufacturer is not guaranteed or endorsed by the publisher. The pain caused by muscle weakness and hypoesthesia is also included. Patients can work with their doctors to understand which herbs may be safe and helpful. Chinese herbal medicine is a complex area and it's best to see an experienced practitioner rather than trying to treat yourself.

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Cancer-fighting effects of herbal extracts -

As the most common herbal medicine in the treatment of prostate cancer and its various extracts have been shown to have anti-prostate effects, this plant is widely used in Europe for the treatment of benign prostatic hyperplasia The most important compounds in nettle root, which have pharmacological effects, include lignans, sterols, flavonoids, polysaccharides, lectins, and fatty acids 32, There is also linoleic acid in nettle root, which lowers cholesterol, thus lowering testosterone levels Aqueous extract of nettle leaves significantly inhibits the activity of adenosine deaminase in prostate tissue.

Also, the presence of hydrophilic steroid compounds in nettle root extract inhibits the activity of the sodium-potassium pump of the prostate membrane, thereby suppressing the metabolism and cell growth of the prostate It has also been reported that nettle root extract has anti-proliferative properties on prostate cells in the laboratory Conrad et al.

In a study by Nahata A, Dixit V the effects of nettle remediation on testosterone mouse prostatic hyperplasia showed that nettle herb could be used as an effective drug to treat prostate hypertrophy by inhibiting the 5α-reductase enzyme In , Durak et al.

blueberry extract has hydrophilic steroid compounds. The presence of hydrophilic steroid compounds in nettle root extract inhibits the activity of the sodium-potassium pump of the prostate membrane, thereby suppressing the metabolism and cell growth of the prostate Herbal dichromethanol extract can be a good candidate as an anti-cancer compound.

Lycopene is a chemical found in some fruits and vegetables and is highly effective in inhibiting prostate cancer. Lycopene is currently being studied in many research centers. Lycopene is a carotenoid in the blood that has antioxidant properties A new study in mice found that lycopene can inhibit prostate tumor formation specifically attack on target tissue A randomized clinical trial showed that in men with high-grade neoplasia of the prostate tissue, the administration of lycopene was able to reduce the progression and severity of cancer Another study found that taking lycopene reduced prostate specific antigen PSA levels and slowed the progression of the disease in patients 42, Saw Palmetto.

Iranian date palm fruit extract has been shown to have the greatest effect on improving symptoms, increasing urinary flow, and reducing nocturnal enuresis, which is comparable to Finasteride the most effective drug in the treatment of benign human hyperplasia of human prostatitis 44, This plant is mostly used in benign prostatic hypertrophy and is used in the treatment of large prostate.

Research shows that high-concentration sawdust extract blocks the enzyme 5-alpha reductase, which converts testosterone to dihydrotestosterone, and acts like a chemical and fumigant blocking drug like finasteride. Saw palms contain the antioxidants epicatechin and methyl gallate, which prevent cell damage, reduce inflammation, and protect against chronic disease, and in mice with enlarged prostate glands.

Reduced swelling and some inflammatory markers, including interleukin-6, have been reported. Saw palms inhibit the conversion of testosterone to di-hydro-testosterone in prostate tissue Garlic contains a large amount of an ingredient called Allicin , which stimulates blood circulation and blood flow to the genitals of men and women.

The hydrogen sulfide in garlic has a direct relationship with prostate health because it protects against benign prostatic hyperplasia. One study found that garlic has properties that can kill cancer-causing factors. There is a compound in garlic that has been shown to inhibit the growth of prostate cancer cells in the living environment Preliminary studies on garlic suggest that a compound called alum has high anti-tumor properties in prostate cancer.

A separate study found that a component of garlic called S-allyl mercaptoist had high antitumor properties and converted residual testosterone products into low-risk substances A review study has shown that aluminum can powerfully inhibit the proliferation of Lncap prostate cancer cell lines Another review study confirms the anti-tumor effects of garlic on prostate cancer Another study has shown that a compound in garlic called di-allyl disulfide can inhibit the growth of prostate cancer cells.

An additional study showed that di-allyl di-sulfide could affect the programmed cell death of prostate cancer apoptosis and play an important role in controlling this cancer Curcumin is a natural product found in turmeric that has unique biological and medicinal properties due to its special chemical structure.

Curcumin , through various cellular and molecular mechanisms, inhibits the onset of cancer cell formation or inhibits its growth. Studies in mice with Curcumin have shown anti-carcinogenic properties in the treatment of various cancers. While the mechanism of action of this substance is still unknown, curcumin is also effective in the human cancer cell category A new study in mice has shown that curcumin has been shown to inhibit the proliferation of prostate cancer cells both androgen-dependent and androgen-independent.

A study has found that curcumin blocks the growth of prostate cancer cells by inhibiting the activity of the enzyme tyrosine kinase, a receptor for an epiphyseal growth factor One study found that curcumin was an effective substance in treating androgen-dependent prostate cancer In another study, curcumin was able to inhibit prostate cancer cells by blocking the effects of factors such as NF-κB and AP-6 Pumpkin seeds.

Pumpkin seeds, extracts, and pumpkin oil are very important in improving men's reproductive ability. It is also recommended to use this plant in the daily diet to reduce the side effects of lead contamination and the desired sexual status. The most important ingredients in pumpkin seed extract contain unsaturated fatty oils, vitamin E, and phytosterols.

In addition to these compounds, this plant also contains minerals, pigments, and phenolic compounds. Today, pumpkin oil is used as an effective treatment for benign prostatic enlargement, According to the researchers' findings, the use of pumpkin seed oil in clinical terms can be effective as a complementary and alternative drug treatment for benign prostatic hyperplasia The absorption of pumpkin seed extract is associated with a reduction in the symptoms of benign prostatic hypertrophy.

Pumpkin extract improves hormones secreted by testicular tissue and is, therefore, is an effective extract in male infertility. Pumpkin seed extract reduces the number of abnormal sperm and has a great effect on the prevention and treatment of male infertility 62, Pumpkin extract inhibits the enzyme 5-alpha reductase and prevents the conversion of testosterone to dihydrotestosterone Green tea.

Green tea has been shown to have inhibitory effects on prostate cancer several times. Studies on rats have shown that green tea has been shown to inhibit the enzyme 5 alpha-reductase This enzyme converts testosterone to dihydrotestosterone, which causes dihydrotestosterone to cause carcinogens in the prostate.

The strongest compound in green tea is epigallocatechin 3-gallate. A study in mice showed that green tea even on other enzymes and prostate cancer growth factors also have a restraining effect.

The combination of epigallocatechin 3-gallate is found in high concentrations in the blood of green tea consumers. Green epigallocetin 3 - gallstones and other green tea compounds inhibit an enzyme called the proteasome. Proteaseam is a key factor in the formation of prostate cancer 66, Green tea can block the formation of prostate cancer, as well as reduce the risk of developing prostate cancer by lowering the levels of polyamines.

Green tea polyphenols not only inhibit the growth of prostate cancer cells in mice but also prevent their metastasis to nearby tissues 66, Soybeans have adequate amounts of phytosterols vegetable fats.

These phytosterols are known to decrease the level of cholesterol properties. Phytosterols have been shown to have positive effects in the treatment of benign hyperplasia.

Saponins are another class of substances found in soybeans. Saponins Triterpene glycosides are also found in many other types of plants such as Lagenaria siceraria 69 , and Holothuria leucospilota Soy saponins are olenan-type tripotropic glycosides.

Soy saponins are involved in several biological activities such as hepatic protection, anti-cancer, antioxidant, anti-lipid, etc. They are known to have various anti-cancer properties.

Phytates are another class of substances found in soy. These substances increase the body's ability to kill natural cells. Studies show that phytates also have anti-cancer activity.

On the other hand, phytate prevents proteolysis by inhibiting the activity of digestive proteins. The anti-cancer activity of myoinositol Hexa phosphate is achieved by reducing cell proliferation and increasing the differentiation of malignant cells, leading to the return of cells to their normal phenotype The phytoestrogens found in soy show anti-estrogenic effects, and again, these properties enhance the function of preventing prostate cancer in soy.

In general, phytoestrogens can have an inhibitory effect on the enzyme, which is thought to be due to their effect on inhibiting-5 alpha-reductase 73, In this article, a review of several compounds isolated from natural resources and medicinal plants with significant medical and pharmacological effects is discussed in cancer treatment supplementation and benign prostatic hyperplasia.

This article provides an overview of the importance and value of complementary therapies and nutrition in the treatment and prevention of prostate cancer. Due to the costs and side effects of chemical drugs, the use of medicinal plants with lower costs and side effects and with much antioxidant activity is much more economical.

Special thanks to Urology Research Center URC , Tehran University of Medical Sciences, Tehran, Iran. Authors' contributions. All authors contributed equally. Conflict of interest. All authors claim that there is no competing interest.

There was no founding. Ethics statement. Not applicable. Data availability. PSA Prostate specific antigen. VEGF Vascular endothelial growth factor. Mirzaei, A. The Effect of Herbal Extracts on the Treatment and Prevention of Prostate Cancer: A Literature Review.

Translational Research in Urology , 1 2 , doi: Akram Mirzaei; Fatemeh Khatami; Mehdi Ebrahimi; Seyed Habibollah Mousavibahar; Behzad Narouie. Translational Research in Urology , 1, 2, , Translational Research in Urology , ; 1 2 : Toggle navigation.

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Today, prostate cancer is the second leading cause of death in men. Disorders of this gland have side effects on fertility and cause urinary problems. As people age, the prostate gland can have some problems, including benign hyperplasia and prostate cancer, which are caused by abnormal growth of the gland.

Various natural supplements that affect the growth and proliferation of prostate cells have been found using epidemiological, laboratory, and clinical studies. With the help of findings from herbal medicine, the problems caused by prostate disorders can be controlled and treated largely.

In this review article, the mechanism of action of some of these natural substances is considered including garden thyme, spirulina algae, Ruta graveolens L, wheat germ, nettle root extract Urtica dioica, lycopene, saw palmetto, garlic, curcumin, pumpkin seeds, green tea, and soy.

The main functional mechanism of most of these plant extracts may be the inhibition of the enzyme 5 alpha-reductase.

The purpose of writing this article is to introduce and use some medicinal plants that help treat prostate cancer. Full Text. Introduction The prostate is one of the glands in the reproductive system of men, and its lesions and diseases are of great prevalence and importance 1.

Garden thyme There are compounds in the hydro-alcoholic extract of garden thyme that inhibit these enzymes and reduce oxidative stress 5, 6. Spirulina algae Spirulina algae are one of the plants that are rich in antioxidant compounds.

Ruta graveolens L Ruta graveolens is a medicinal herb that has been applied for a long time versus several diseases. Wheat germ wheat germ extract FWGE; trade name AVEMAR Wheat germ is a nutrient with high nutrients and high nutritional value Nettle root extract Urtica dioica Nettle is a plant belonging to the Urticaceae family that is used to treat a variety of diseases.

Lycopene Lycopene is a chemical found in some fruits and vegetables and is highly effective in inhibiting prostate cancer. Saw Palmetto Iranian date palm fruit extract has been shown to have the greatest effect on improving symptoms, increasing urinary flow, and reducing nocturnal enuresis, which is comparable to Finasteride the most effective drug in the treatment of benign human hyperplasia of human prostatitis 44, Garlic Garlic contains a large amount of an ingredient called Allicin , which stimulates blood circulation and blood flow to the genitals of men and women.

Curcumin Curcumin is a natural product found in turmeric that has unique biological and medicinal properties due to its special chemical structure. Pumpkin seeds Pumpkin seeds, extracts, and pumpkin oil are very important in improving men's reproductive ability.

Green tea Green tea has been shown to have inhibitory effects on prostate cancer several times. Soy Soybeans have adequate amounts of phytosterols vegetable fats. Conclusions In this article, a review of several compounds isolated from natural resources and medicinal plants with significant medical and pharmacological effects is discussed in cancer treatment supplementation and benign prostatic hyperplasia.

Acknowledgments Special thanks to Urology Research Center URC , Tehran University of Medical Sciences, Tehran, Iran. Authors' contributions All authors contributed equally.

Conflict of interest All authors claim that there is no competing interest. Funding There was no founding. Ethics statement Not applicable.

Data availability Not applicable. Abbreviations PSA Prostate specific antigen VEGF Vascular endothelial growth factor. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, et al. Cancer statistics, CA: a cancer journal for clinicians.

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Beyond six scents: defining a seventh Thymus vulgaris chemotype new to southern France by ethanol extraction. Flavour and fragrance journal. Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, A.

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Oxidative medicine and cellular longevity. Li X-L, Wong Y-S, Xu G, Chan JC. European journal of nutrition. Miranda M, Cintra R, Barros SBdM, Mancini-Filho J. Antioxidant activity of the microalga Spirulina maxima. Brazilian Journal of Medical and biological research.

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PLoS One. Al-Snafi AE. A review on Cyperus rotundus A potential medicinal plant. IOSR Journal Of Pharmacy. ZHU KX, ZHOU HM, QIAN HF. Comparative study of chemical composition and physicochemical properties of defatted wheat germ flour and its protein isolate. Journal of food biochemistry.

Adibmoradi M, Morovvati H, Moradi HR, Sheybani M-T, Amoli JS, Mazaheri Nezhad Fard R. Protective effects of wheat sprout on testicular toxicity in male rats exposed to lead. This is an important step for many reasons. Doctors also know which herbs may interact with certain drugs.

If appropriate, they may recommend herbs to address specific symptoms or side effects. By working with their doctors, patients can ensure they only explore using safe herbs.

In addition to talking with their doctors, patients can take some steps on their own. This may help them feel empowered and better educated about herbal medicine. Examples of patient research can include:. Patients and their doctors can then discuss these findings and any questions patients may have.

By working together, patients can feel confident their treatment plan supports their goals. Some research has studied the effects of herbal medicines on cancer patients.

Though there is no evidence herbs can cure cancer, findings show some herbs may help alleviate certain cancer-related issues.

These potential benefits of herbal medicine apply to cancer in general and may include mesothelioma. Notable herbs include black cohosh, curcumin, marijuana , mistletoe extracts and resveratrol.

Despite potential benefits, there are still risks to be aware of. For example, marijuana may help with nausea. But it may also interfere with immunotherapy treatment. It is vital for patients to talk with their doctors before taking these or other herbal treatments.

Potential benefits and concerns with herbal medicine vary on a case-by-case basis. Turmeric is a flowering plant with a vibrant, orange-colored root. This plant contains the chemical compound curcumin, which is available as an herbal supplement.

Evidence from cancer studies suggests curcumin may:. A study of curcumin in non-mesothelioma cancers found various benefits. Some patients with solid tumors took curcumin while receiving chemotherapy.

They experienced significantly lower rates of chemotherapy-related side effects. These patients also needed fewer medications to manage chemotherapy side effects.

These studies are not mesothelioma-focused but may still interest patients. These study findings are encouraging, but they cannot replace the guidance of an oncologist. For their own safety, patients should talk with a mesothelioma doctor before taking any herbal medicine.

Mistletoe is a plant that grows on several different types of trees. Its extracts can vary because of the specific species of mistletoe and the tree it grows on.

As a result, efficacy for treating conditions may be inconsistent. Some experts criticize the methods and parameters of many mistletoe extract studies.

These weaknesses may call their results into question. Reishi is a large, dark mushroom used in several traditional medical systems. This mushroom has been a popular supplement in recent years. It has many claims of health benefits and abilities to treat serious conditions.

But the actual evidence of its effects on cancer indicates reishi:. The positive effects of reishi mushrooms may be due to the presence of beta-glucans.

Beta-glucans are natural substances found in items like mushrooms, grains and yeasts. Some research suggests that mushroom beta-glucans may help fight cancer, enhance memory and reduce infection frequency and severity.

Reported side effects of reishi are relatively mild and include nausea and insomnia. These side effects and risks may seem low. But doctors can decide if taking reishi is safe for mesothelioma patients.

Black cohosh is a member of the Buttercup family of plants, native to North America. It is commonly used in Europe. Black cohosh may be used to treat many conditions, including menopausal symptoms and irregular heartbeat. Mood disorders like irritability, anxiety and depression may also be treated with the herb.

Experts say the data for black cohosh is inconclusive. But as a relatively safe herb, it warrants more research. In general, black cohosh is very well-tolerated and rarely causes serious side effects. Serious side effects likely result from product quality issues, not the herb itself.

But black cohosh may interfere with statins for cholesterol management. This is a good example of why patients should speak with their doctors before taking any herbal products. The dried leaves and flowers of Cannabis plants, also called marijuana, contain cannabinoids.

These are popular for a variety of recreational and medicinal uses. Evidence suggests marijuana may:. Reported side effects of marijuana use include bloodshot eyes, dizziness, increased heart rate and sleepiness. Some evidence suggests cannabis use may limit the efficacy of immunotherapy.

This may be a serious risk for mesothelioma patients receiving this cutting-edge treatment. Doctors can explain if marijuana is a safe addition to their treatment plans. Other herbs have some studies and evidence of their use against cancer.

These have less evidence than others but may still offer some benefit. Other herbs with potential benefits include:. Other studies have found clear evidence of harm when using certain herbs. These concerns may be both general and cancer-specific.

Herbs that may harm cancer patients include:. Regardless of how promising an herb seems, there may be risks. It is best to speak with healthcare teams before beginning any herbal supplementation. Questions About Alternative Mesothelioma Treatments?

Ask experienced mesothelioma advocate Jennifer Lucarelli Ask a Question. Side effects vary by the type of herb. These effects may be more common with some herbs than others.

Mesothelioma specialists can explain which herbs may have negative side effects. Common herbal side effects include chills, diarrhea, insomnia, nausea and skin irritation. Doctors can also determine if any herbs may interact negatively with other treatments.

There are other serious risks with some herbs that may impact patients. For example, some herbs may increase the effects of anticoagulant drugs blood thinners. Herbs that sometimes cause this effect include dang gui, curcumin, ginger and reishi. Cancer patients who take blood thinners may face this risk.

Herbs may seem like a natural and safe way to improve health. But herb and drug interactions are complex and varied.

Some herbs have both potential benefits and risks to cancer patients. But other herbs may be dangerous or offer little to no proven benefits. It may be safest for some cancer patients to avoid these herbs altogether.

Other herbal medicines have limited research. These herbs include cafestol, kahweol, hesperidin and licorice root. Until there is more research, their potential risks and side effects remain unknown. As a rare disease, existing mesothelioma research has not involved patients taking herbal medicine.

Some mesothelioma patients may be interested in joining clinical trials for herbalism. Their doctors can explain if any options are available and may be a good fit. Some cancer centers may also have information on their websites about clinical trials.

Researchers in other countries often run reputable clinical trials, too. Interested patients can find a clinical trial database online at ClinicalTrials. Privacy policy. As the Medical Editor at Mesothelioma. com, she ensures our pages and posts present accurate, helpful information. Linda Molinari has more than 15 years of experience as a writer and advocate for mesothelioma patients and a ban on asbestos.

Written by Katy Moncivais, Ph. Reviewed by Linda Molinari Editor in Chief. Speak With a Mesothelioma Survivor Connect With Heather.

Home Treatment Alternative Treatments Herbal Medicine. Herbal Medicine Overview What Is Herbal Medicine for Cancer? What Is the Difference Between Herbal Medicine and Healthy Foods?

Some herbs, like parsley or turmeric, are common food ingredients or spices. These herbs may also come in supplement form.

Chemotherapy is nowadays the Cancer-fighting effects of herbal extracts treatment Effective belly fat reduction human cancers. Chemotherapeutic gerbal target rapidly dividing cancer cells to suppress tumor progression, however, Cancer-figting Cancer-fighting effects of herbal extracts heerbal often leads Cancer-fightiny significant side extrwcts that might be intolerable to cancer patients. Multi-component herbal products have been used for thousands of years for the treatment of multiple human diseases. This study aims to systematically summarize and evaluate the experimental and clinical evidences of the efficacy of multi-component herbal products in improving chemotherapy-induced side effect. Literature was retrieved from PubMed database and evaluated based on the side effects described. Calling this number connects you with a Extrwcts Advocate at The Mesothelioma Website performance analysis, the nation's most trusted berbal resource. Extradts Patient Advocates can Extracys guide you effdcts your Detoxification for cancer prevention one through the steps to take after a mesothelioma diagnosis. Our team has a combined experience of more than 30 years in assisting cancer patients, and includes a medical doctor, an oncology registered nurse and a U. For example, some herbs can prevent chemotherapy and radiation therapy from killing cancer cells. Certain herbs enhance the effect of chemotherapy in a toxic way that leads to unwanted side effects.