Depression is a mental health disorder, which varies from mild to severe changes in mood and affects physical, mental and behavior health 1. According to International Classification of Diseases and Diagnostic and Statistical Manual-IV, depression episodes catechinw recognized as an individual suffering from depressed or sad mood, Ebhancement a loss of energy, Bone health supplements activity or Fnhancement of interest in activities, Moid results in a significant reduction in productivity and has a negative impact on overall health 1.
The World Health Organization projects rnhancement major depression as a leading oMod of disease worldwide by 2. There are various factors that play a role in the development of major depression, such as changes in environmental factors, socioeconomic conditions, catechns lifestyle, nutrition and ehancement habits 1.
These conditions are linked enhancwment impacting stressful events in enhanceent. Continuous exposure to stress can cause enhancfment compensatory increase Natural thermogenic metabolism boost synthesis and concentration of catechisn, specifically serotonin, norepinephrine catcehins dopamine in brain 3which are responsible for regulating appetite, Essential vitamin foods drive for sleep, emotions, stress and sexuality 3.
Enhncement the adaptive consequence, changes in the nervous system can be excessive, leading to an increase in vulnerability to enhancemen pathology of depression 3. Cstechins exposure to stressful events not only catecuins neurotransmitter eenhancement but also induces neuroinflammation 4increase oxidative stress 5 cqtechins affects the hypothalamic-pituitary-adrenal Moid axis 4.
Changes in neurochemical levels can result in dampening the dnhancement or Dairy-free weight control impact of Mopd and induce Maximizing fat loss response that impairs the ability in dealing with stress 6.
Current ctaechins mainly target monoamines enhsncement however, catehcins treatment is not catecins for many patients 7. An alternative approach is required to catechkns neuroinflammation and resultant oxidative stress.
Associations between oxidative stress and inflammatory cytokines are well established in major depressive disorders 5. Oxidative stress is an outcome of imbalance between oxidant and antioxidant levels that enhancemen lipids and various other cellular biomolecules, and results in the generation of various inflammatory Mod 5.
It was Low-fat snack options that oxidative stress is elevated in major dnhancement syndrome and suppressed by standard Bone health supplements drugs, such as amitriptyline, Mood enhancement catechins of imipramine 8.
Thus, the present study was designed to target Mood stress that resulted from catechinss stress. Diet is important in maintaining health. Epigallocatechingallate, a catechin found in green tea, has shown catechol-o-methyltransferase inhibitory enuancement in vitro Extract of catefhins has shown aphrodisiac effect in the previous study, which is suggesting that catechin might alter monoamine levels in the brain In chronic corticosterone-injected rats, Lycopene and liver health administration showed a decrease in depression and anxiety-like behaviors However, these described corticosterone injections may not reflect ehhancement depression accurately.
The chronic wnhancement mild catschins Mood enhancement catechins model in rodents mimics responses similar to stressful life events in humans Carboxymethyl cellulose CMC was purchased from Enhxncement Chemie Enhandement.
and hydrogen peroxide, sodium bicarbonate, potassium dihydrogen phosphate and disodium hydrogen phosphate were purchased from HiMedia Laboratories Pvt. A total of 24 male Sprague Dawley rats Respiratory health and COVID-, 12 weeks; weight, g were obtained from the Central Moood Research Facility of the Ebhancement Academy of Higher Education.
Animals catexhins acclimatized for 7 days before initiating the experiment. Rats were kept in sterilized propylene cages containing cwtechins husk and were provided with food and water ad libitum.
The study was Moodd by the Catechijs Animal Ethics Datechins of Enhncement Medical College Manipal, India; no. All the experiments were performed catecuins to the Enhamcement for the Purpose Maximizing fat loss Control and Supervision of Experiments on Cattechins guidelines as suspension in 0.
All the catechinns were administered with their treatments daily ennancement am and 1 h prior to daily stress exposure for enhancemenr weeks.
Enhancemeny drug suspensions were prepared enuancement Mood enhancement catechins a daily basis in 0. The CUMS procedure was performed as previously described It involved the daily application of various stressors for a period of 8 weeks.
The stressors included: i No food for 24 h, ii no water for 20 h, iii tail pinch for sec, iv electric shock at 0. They were applied following the schedule shown in Table I. Vehicle control rats were not exposed to any stressors. NF, no food for 24 h; NW, no water for 20 h; CT, cage tilt for 24 h; TP, tail pinch for sec; RS, restraint for h; ES, electric shock for sec; FS, forced swim for min; NFW, no food and water for h; PT, parameter testing FST and SPT ; FST, forced swim test; SPT, sucrose preference test.
In the next phase, the test phase, sucrose compared with water consumption was measured. Sucrose consumption was measured every 24 h and a baseline value was obtained as the average consumed in 3 consecutive days. The tests were performed in weeks 4 and 8, and food and water were removed for 24 h prior to the experiment.
After 24 h, the consumed volume was measured in both bottles. Rats were individually placed in a water tank made of glass height, 80 cm; diameter, 30 cm at ˚C.
Experiments were performed in two sessions. In the first session, animals were trained to swim for 15 min. The second session test session was conducted 24 h after the training session and 1 h post treatment. In this test session, rats were studied for immobility time for 10 min.
The study was conducted in weeks 4, 6 and 8. Immobility was recorded as floating, with small movements or the head above the surface of the water. The behavior was recorded using a video camera and scored manually 14 Once the animals reached the surgical plane of anesthesia, an intracardiac perfusion was given using PBS, pH 7.
The homogenate was centrifuged at 10, x g for 30 min at 4˚C and the supernatant was used to determine endogenous antioxidant levels, including catalase, reduced glutathione GSHsuperoxide dismutase SOD and malondialdehyde MDA using a UV spectrophotometer as per manufacturer instruction.
A total of 50 µl tissue homogenate was added to 3 ml of 50 mM potassium phosphate buffer PPB; pH 7. Changes in absorbance were recorded for 1 min. The supernatant was collected after centrifugation 1, x g, 10 min, 4˚C. A total of µl supernatant was added to a mixture of 3 ml PB 0.
Absorbance was recorded at nm. Tissue homogenate 0. The resulting mixture was centrifuged at 1, x g for 10 min at 25˚C. The absorbance in the supernatant was directly recorded at nm.
Changes in the absorbance were recorded at nm over 1 min at room temperature. The change in absorbance was extrapolated to a standard curve recorded for SOD activity.
Data were analyzed using GraphPad Prism 5. Statistical comparisons were performed using one-way ANOVA followed by Tukey's multiple comparison tests. Data are expressed as the mean ± standard error of the mean representative of six experimental repeats.
CUMS control rats showed a significant increase in the immobility time in weeks 4, 6 and 8 compared with the vehicle control group Escitalopram treated animals subjected to CUMS displayed a significant reduction in immobility during the 10 min FST in weeks 4, 6 and 8, with Catechin treated animals subjected to CUMS also showed a significant reduction in immobility time compared with the CUMS control at the end of week 4, 6 and 8, with Catechin affects immobility time in FSTs.
Rats were subjected to CUMS and treated with escitalopram or catechol from 8 weeks. At the end week 4, 6 and 8 in rats underwent FSTs and the immobility times were recorded. FST, forced swim test; CUMS, chronic unpredictable mild stress.
Additionally, in comparison with the baseline values recorded for the CUMS control group before subjecting the animals to CUMS, volumes of consumed sucrose decreased over the course of the experiment and exposure to CUMS, indicating anhedonia. Catechin administration affects sucrose consumption in rats subjected to CUMS.
At week 4 and 8, the preferential sucrose consumption was evaluated. CUMS, chronic unpredictable mild stress.
The endogenous antioxidant activity, namely catalase and SOD activity, and reduced GSH and MDA levels were evaluated in brains of all animals after completion of the 8-week study Fig. Catechin treatment in rats subjected to CUMS affects antioxidant levels in the brain. After 8 weeks animals were sacrificed and the brains were collected for measurement regarding antioxidant levels; catechol and SOD activity, as well as GSH and MDA levels were determined.
CUMS, chronic unpredictable mild stress; SOD, superoxide dismutase; GSH, glutathione; MDA, malondialdehyde. The CUMS induced depression model is a suitable model for studying depression-like behavior in rodents.
Chronic exposure to stress leads to behavioral and pathological alterations in rodents that are analogous to those observed in depressed patients Chronic exposure to stress results in alterations in the central neurotransmitters, including changes in levels and activities of noradrenaline, serotonin and dopamine, in addition to the regulation of specific receptors, disruption of the HPA axis, elevation of cortisol levels leading to the activation of several proapoptotic factors, and the generation of reactive oxygen species ROS causing neurodegeneration and elevating the symptoms of depression 4.
FST is a reliable behavioral test to assess depression in rodents FST is used to evaluate the activity of potential antidepressant drugs in rodent models of depression. The forced immersion of rodents in water for an extended time period leads to characteristic immobility. Antidepressant drugs decrease this immobility time.
In the current study, treatment with catechin significantly reduced the FST immobility time at the end of week 4, 6 and 8 in animals subjected to CUMS compared with the CUMS control group, thereby indicating an antidepressant effect of the compound.
Anhedonia, or the lack of pleasure, is a major depressive symptom in humans It can be assessed in rodents through a reduced preference for sucrose In the current study, regular treatment of CUMS-subjected rats with catechin significantly increased the consumption of sucrose water compared with the CUMS control group after 4 and 8 weeks.
Oxidative stress is one of the main reasons for neurodegeneration 21 and for the further elevation of depression and its symptoms Chronic exposure to stress results in the activation of several proapoptotic factors, the generation of excessive ROS and induces necrosis, thereby causing neurodegeneration, which serves a key role in the pathology of depression 5.
The antioxidant capacity of the brain homogenate is an indicator of oxidative stress 5. Catalase is abundant in peroxisomes. Metabolic activity in cells leads to hydrogen peroxide production that can be toxic to the body causing the generation of ROS and inducing cell damage and death.
Catalases catalyze the conversion of hydrogen peroxide to water and oxygen. Excessive oxidative stress leads to decreased catalase activity resulting in the accumulation of toxic hydrogen peroxide and ROS in the body An increase in oxidative stress is reflected by a decrease in the levels of free radical scavengers, such as catalase, SOD and GSH, and an increase in the free radical generators, such as lipid peroxidation that is quantified through MDA levels
: Mood enhancement catechins| Neuroprotective Effects of the Green Tea Components Theanine and Catechins | Carnevale, R. Journal of Psychiatric Research. Evidence-Based Complementary and Alternative Medicine. To minimize these risks, choose low-sugar options or make your own kombucha at home, consume in moderation, and consider alternating with other healthy drinks like green tea or lemon water. Avoid the negative effects of caffeine by incorporating these non-stimulant supplements into your daily routine:. According to the data of the European Food Safety Agency EFSA , there are mg of catechins in every mL of green tea Prasanth et al. Article Google Scholar Feng, L. |
| REVIEW article | FST is a reliable behavioral test to assess depression in rodents FST is used to evaluate the activity of potential antidepressant drugs in rodent models of depression. The forced immersion of rodents in water for an extended time period leads to characteristic immobility. Antidepressant drugs decrease this immobility time. In the current study, treatment with catechin significantly reduced the FST immobility time at the end of week 4, 6 and 8 in animals subjected to CUMS compared with the CUMS control group, thereby indicating an antidepressant effect of the compound. Anhedonia, or the lack of pleasure, is a major depressive symptom in humans It can be assessed in rodents through a reduced preference for sucrose In the current study, regular treatment of CUMS-subjected rats with catechin significantly increased the consumption of sucrose water compared with the CUMS control group after 4 and 8 weeks. Oxidative stress is one of the main reasons for neurodegeneration 21 and for the further elevation of depression and its symptoms Chronic exposure to stress results in the activation of several proapoptotic factors, the generation of excessive ROS and induces necrosis, thereby causing neurodegeneration, which serves a key role in the pathology of depression 5. The antioxidant capacity of the brain homogenate is an indicator of oxidative stress 5. Catalase is abundant in peroxisomes. Metabolic activity in cells leads to hydrogen peroxide production that can be toxic to the body causing the generation of ROS and inducing cell damage and death. Catalases catalyze the conversion of hydrogen peroxide to water and oxygen. Excessive oxidative stress leads to decreased catalase activity resulting in the accumulation of toxic hydrogen peroxide and ROS in the body An increase in oxidative stress is reflected by a decrease in the levels of free radical scavengers, such as catalase, SOD and GSH, and an increase in the free radical generators, such as lipid peroxidation that is quantified through MDA levels The present study showed that catechin significantly increased the levels of endogenous antioxidants in the brain, including catalase, SOD and GSH, and significantly decreased the levels of MDA, thereby preventing lipid peroxidation in the brain. In the current study, antidepressant effects of catechin were compared with those of escitalopram, a known antidepressant. In week 4, the immobility time in the escitalopram group was significantly decreased compared with the catechin group, while the sucrose consumption was significantly higher in the catechin group compared with the escitalopram group. There was no significant difference in oxidative stress indicators between the catechin and escitalopram groups except for the GSH activity. These results indicated that oxidative stress may not be the only target of catechin. Thus, it was suggested that regular treatment with catechin ameliorates the behavioral and neurochemical responses involved in the pathophysiology of depression due to its neuroprotective and antioxidant potential and the potential modulation of neurotransmitter and HPA activity, thus exhibiting antidepressant-like effects. CUMS is associated with neuroinflammation and correlates with the brains' oxidative status This mechanistic aspect was not further explored in the current study. The current study did not assess monoamine levels or changes of expression of proteins in the brain; these aspects may be explored in upcoming studies. Evaluating further underlying mechanisms in addition to the antioxidant axis may also be subject of future studies. Additionally, studies may assess molecular mechanisms, cortisol levels and mRNA expression in the brain and could help decoding the exact mechanism behind the antidepressant activity of catechin. The outcomes of the present study supported ideas to use catechin as a nutritional supplement or as an adjuvant to the conventional antidepressant therapy to augment the effect of drugs 7. The antioxidant property exhibited by catechin, as well as its ability to modulate the levels of neurotransmitters may exert a long-term synergism with first-line drugs. However, further research is required to assess possible drug interactions in the co-administration with other drugs. In conclusion, catechin showed prevention of anhedonia in Sprague Dawley rats subjected to CUMS that was observed by improvements in the sucrose preference test and reduced immobility times in FST. These observations were supported by a determined reduction in oxidative stress. Thus, it was suggested that catechin may be a novel therapeutic agent in treating stress-associated disorders, such as depression. The authors like to thank Ms Ashwathi R. Hegde and Dr Muthukumar Amirthalingam Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education for their support in this study in procuring chemicals. The authors further thank Mr. Raju Krishna Ekden and Mr. Shenoy from Micro Labs Ltd. for providing Escitalopram oxalate. AR, MG, RS, NaK, CMR and NiK designed the study, analyzed the data and drafted the manuscript. AR, MG and MK performed the in vivo behavioral study. SS, AR, MG and NiK performed the antioxidant analysis. All the authors read and approved the manuscript. Institutional Animal Ethics Committee of Kasturba Medical College approved the experimental procedures approval no. Patel V: Cultural factors and international epidemiology. Br Med Bull. Lépine JP and Briley M: The increasing burden of depression. Neuropsychiatr Dis Treat. Wang F and Pereira A: Neuromodulation, emotional feelings and affective disorders. Mens Sana Monogr. Slavich GM and Irwin MR: From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. Psychol Bull. Lindqvist D, Dhabhar FS, James SJ, Hough CM, Jain FA, Bersani FS, Reus VI, Verhoeven JE, Epel ES, Mahan L, et al: Oxidative stress, inflammation and treatment response in major depression. Anisman H, Merali Z and Hayley S: Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders. Prog Neurobiol. Sarris J, Murphy J, Mischoulon D, Papakostas GI, Fava M, Berk M and Ng CH: Adjunctive nutraceuticals for depression: A systematic review and meta-analyses. Am J Psychiatry. Behr GA, Moreira JC and Frey BN: Preclinical and clinical evidence of antioxidant effects of antidepressant agents: Implications for the pathophysiology of major depressive disorder. Oxid Med Cell Longev. Ni CX, Gong H, Liu Y, Qi Y, Jiang CL and Zhang JP: Green tea consumption and the risk of liver cancer: A meta-analysis. Nutr Cancer. Am J Chin Med. Zhu BT, Shim JY, Nagai M and Bai HW: Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by - -epigallocatechinO-gallate. Rai A, Das S, Chamallamudi MR, Nandakumar K, Shetty R, Gill M, Sumalatha S, Devkar R, Gourishetti K and Kumar N: Evaluation of the aphrodisiac potential of a chemically characterized aqueous extract of Tamarindus indica pulp. J Ethnopharmacol. Lee B, Sur B, Kwon S, Yeom M, Shim I, Lee H and Hahm DH: Chronic administration of catechin decreases depression and anxiety-like behaviors in a rat model using chronic corticosterone injections. Biomol Ther Seoul. Gill M, Kinra M, Rai A, Chamallamudi MR and Kumar N: Evaluation of antidepressant activity of methanolic extract of Saraca asoca bark in a chronic unpredictable mild stress model. Ministry of Environment and Forests and Climate Change Government of India: Compendium of CPCSEA The bioactive compounds in green tea may support brain health. Green tea could be linked with less likelihood of neurodegenerative disease, but more clinical studies in humans are needed to clarify any effect. A review of studies has found that drinking green tea, or using green tea extract , could be linked to better oral health. However, most of the research on this subject did not examine human subjects. While results are promising, more clinical research in humans is needed. There is encouraging evidence that green tea could help with oral health, but additional studies are needed. A review found that green tea may help reduce blood sugar while fasting in the short term but does not seem to have an effect on blood sugar or insulin in the long term. Other reviews found no effects on any markers of blood sugar management in people with type 2 diabetes, so the findings are inconclusive. Read more about green tea and diabetes. The research is mixed on the role green tea may play in lowering the risk of type 2 diabetes, or helping with the overall management of type 2 diabetes. A recent review of studies suggests that regularly drinking green tea could lower many risk factors of heart disease , such as blood pressure or lipids. That said, there is still a lack of consistent , long-term evidence in human clinical trials able to show cause and effect. Green tea could help lower some markers of heart disease. Studies show that people who drink green tea have a lower chance of heart disease, but more clinical evidence is needed to confirm the findings. Several studies show that green tea may help with weight loss. But, green tea does not seem to make any changes to your levels of hunger and fullness hormones , which help regulate your appetite. Some studies show that green tea may lead to increased weight loss and lower fat accumulation in the abdominal area. Green tea may have protective compounds against cancer and heart disease, which may help you live longer. Research from Japan found that those who drank five cups or more per day had a lower chance of death from all causes than those drinking one cup or less. Generally speaking, most people can enjoy green tea daily as part of an otherwise balanced eating plan. While the evidence is mixed, studies seem to show health benefits with three to five cups 24 to 40 ounces consumed daily. Drinking green tea has many benefits. It is high in antioxidants, which may help prevent or remedy cellular damage and support your overall health. This includes reducing certain markers of inflammation which may decrease the risk of cognitive decline. It may even have some properties that help protect against cancer and heart disease. It may be good for your health to drink cups of green tea a day. Keep in mind that most green tea contains caffeine, unless it has been decaffeinated, so drinking more than cups daily is not advised. Some research-based evidence suggests drinking green tea can help reduce body fat, including in the abdomen. However, more well-controlled human studies are needed to show a cause-and-effect relationship. You may want to consider making green tea a regular part of your lifestyle in a way that meets your personal health goals and taste preferences. Read this article in Spanish. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. VIEW ALL HISTORY. Green tea extract is a concentrated supplemental form of green tea. Here are 10 science-based benefits of green tea extract. Drinking lemon and green tea together is a great way to get the health benefits of these two ingredients. Puri A, Nguyen HX, Banga AK. Microneedle-mediated intradermal delivery of epigallocatechingallate. Reis GM, Faccin H, Viana C, da Rosa MB, de Carvalho LM. Vitis vinifera L. cv Pinot noir pomace and lees as potential sources of bioactive compounds. Int J Food Sci Nutr. Rojas LB, Quideau S, Pardon P, Charrouf Z. Colorimetric evaluation of phenolic content and GC-MS characterization of phenolic composition of alimentary and cosmetic argan oil and press cake. Scalia S, Marchetti N, Bianchi A. Comparative evaluation of different co-antioxidants on the photochemical- and functional-stability of epigallocatechingallate in topical creams exposed to simulated sunlight. Sharma A, Gupta P, Verma AK. Preliminary nutritional and biological potential of Artocarpus heterophyllus L. shell powder. J Food Sci Technol. Shi M, Nie Y, Zheng X-Q, Lu J-L, Liang Y-R, Ye J-H. Ultraviolet B UVB Photosensitivities of tea catechins and the relevant chemical conversions. Shin MC, Park SK, Jung SH. The inhibitory effect on cytotoxicity and nitric oxide NO of the nano-encapsulated extraction of lipid-soluble green tea leaves. J Nanosci Nanotechnol. Shoko T, Maharaj VJ, Naidoo D, Tselanyane M, Nthambeleni R, Khorombi E, et al. Anti-aging potential of extracts from Sclerocarya birrea A. Hochst and its chemical profiling by UPLC-Q-TOF-MS. BMC Complement Altern Med. Sidgwick GP, McGeorge D, Bayat A. Functional testing of topical skin formulations using an optimised ex vivo skin organ culture model. Arch Dermatol Res. Singh BN, Shankar S, Srivastava RK. Green tea catechin, epigallocatechingallate EGCG : mechanisms, perspectives and clinical applications. Biochem Pharmacol. Skowyra M, Falguera V, Gallego G, Peiró S, Almajano MP. Antioxidant properties of aqueous and ethanolic extracts of tara Caesalpinia spinosa pods in vitro and in model food emulsions. Spizzirri UG, Iemma F, Puoci F, Cirillo G, Curcio M, Parisi OI, et al. Synthesis of antioxidant polymers by grafting of gallic acid and catechin on gelatin. Takahashi T, Yokoo Y, Inoue T, Ishii A. Toxicological studies on procyanidin B-2 for external application as a hair growing agent. Food Chem Toxicol. Tsuchiya H, Sato M, Kato H, Okubo T, Juneja LR, Kim M. Simultaneous determination of catechins in human saliva by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. Wisuitiprot W, Somsiri A, Ingkaninan K, Waranuch N. In vitro human skin permeation and cutaneous metabolism of catechins from green tea extract and green tea extract-loaded chitosan microparticles. Xia J, Song X, Bi Z, Chu W, Wan Y. UV-induced NF-κB activation and expression of IL-6 is attenuated by - -epigallocatechingallate in cultured human keratinocytes in vitro. Int J Mol Med. Yang W, Liu F, Xu C, Sun C, Yuan F, Gao Y. Yang W, Xu C, Liu F, Sun C, Yuan F, Gao Y. Yang W, Yuan F, Gao YX. Interaction of fish collagen peptide with epigallocatechin gallate. Guang Pu Xue Yu Guang Pu Fen Xi. Yoshino S, Mitoma T, Tsuruta K, Todo H, Sugibayashi K. Effect of emulsification on the skin permeation and UV protection of catechin. Yuki K, Ikeda N, Nishiyama N, Kasamatsu T. Mutat Res Genet Toxicol Environ Mutagen. Zhang W, Yang Y, Lv T, Fan Z, Xu Y, Yin J, et al. J Biomed Mater Res B Appl Biomater. Zhong Y, Shahidi F. Lipophilized epigallocatechin gallate EGCG derivatives as novel antioxidants. Zillich OV, Schweiggert-Weisz U, Eisner P, Kerscher M. Polyphenols as active ingredients for cosmetic products. Zillich OV, Schweiggert-Weisz U, Hasenkopf K, Eisner P, Kerscher M. Release and in vitro skin permeation of polyphenols from cosmetic emulsions. Download references. We would like to thank Yeoju-si and Yeoju Institute of Technology Gyeonggi-do, Republic of Korea for their support for this study. Department of Cosmetics Engineering, Graduate School of Konkuk University, Neungdong-ro, Gwangjin-gu, Seoul, , Republic of Korea. Department of Beauty Art, Doowon Technical University, Jurawui-gil, Paju-eup, Paju-si, Gyeonggi-do, , Republic of Korea. Department of Beauty Yakson Care, Yeoju Institute of Technology, Sejong-ro, Yeoju-si, Gyeonggi-do, , Republic of Korea. You can also search for this author in PubMed Google Scholar. JB, NK, YS, and YJK designed the study and analyzed data, and JB, NK, YS, SYK, and YJK wrote the manuscript and figure together. All authors read and approved the final manuscript. Correspondence to You-Jeong Kim. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Open Access This article is distributed under the terms of the Creative Commons Attribution 4. Reprints and permissions. Bae, J. et al. Activity of catechins and their applications. biomed dermatol 4 , 8 Download citation. Received : 21 August Accepted : 08 January Published : 26 February Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. Download PDF. Download ePub. Abstract Background Catechins, which are polyphenol compounds found in many plants and are an important component of tea leaves, are strong anti-oxidants. Research Many studies seek to enhance the effects of catechins on the human body and boost their protective power against UV radiation. Conclusion Continued research on the strong anti-oxidant effects of catechins is expected to result in many advances in the food, cosmetics, and pharmaceutical industries. Background Catechins have many benefits including preventing or reducing skin damage. Full size image. Conclusions Table 1 summarises the activities of catechins and their applications. Table 1 Activities of catechins and their applications Full size table. Availability of data and materials Data sharing not applicable to this article as no datasets were generated or analyzed during the current study. References Aires A, Carvalho R, Saavedra MJ. Article CAS PubMed Google Scholar Aoshima H, Kokubo K, Shirakawa S, Ito M, Yamana S, Oshima T. Article CAS PubMed Google Scholar Arct J, Bielenda B, Oborska A, Pytkowska K. Google Scholar Arct J, Oborska A, Mojski M, Binkowska A, Swidzikowska B. Article CAS PubMed Google Scholar Arruda HS, Pereira GA, de Morais DR, Eberlin MN, Pastore GM. Article CAS PubMed Google Scholar Arruda HS, Silva EK, Pereira GA, Angolini CFF, Eberlin MN, Meireles MAA, et al. Article CAS PubMed Google Scholar Bianchi A, Marchetti N, Scalia S. Article CAS PubMed Google Scholar Bombardelli E. CAS PubMed Google Scholar Chen Y-C, Yu S-H, Tsai G-J, Tang D-W, Mi F-L, Peng Y-P. Article CAS PubMed Google Scholar Cheng H-Y. Article CAS PubMed Google Scholar Choi M-H, Jo H-G, Yang J, Ki S, Shin H-J. Article PubMed Central CAS Google Scholar Cruz L, Fernandes VC, Araújo P, Mateus N, de Freitas V. Article PubMed CAS Google Scholar dal Belo SE, Gaspar LR, PMBG MC, Marty J-P. Article CAS PubMed Google Scholar de Oliveira CA, Hensel A, Mello JCP, Pinha AB, Panizzon GP, Lechtenberg M, et al. Article CAS Google Scholar Demoliner F, de BrittoPolicarpi P, Vasconcelos LFL, Vitali L, Micke GA, Block JM. Article CAS PubMed Google Scholar Feng B, Fang Y, Wei SM. CAS PubMed Google Scholar Feng H-L, Tian L, Chai W-M, Chen X-X, Shi Y, Gao Y-S, et al. Article CAS PubMed Google Scholar Ferreira-Nunes R, Angelo T, da Silva SMM, Magalhães PO, Gratieri T, da Cunha-Filho MSS, et al. Article CAS Google Scholar Ferreira-Nunes R, Gratieri T, Gelfuso GM, Cunha-Filho M. Article CAS PubMed Google Scholar Foyet H, Tsala D, ZogoEssono Bodo J, Carine A, Heroyne L, Oben E. CAS Google Scholar Fung S-T, Ho CK, Choi S-W, Chung W-Y, Benzie IFF. Article PubMed CAS Google Scholar Gallego M, Skowyra M, Gordon M, Azman N, Almajano M. Article PubMed Central CAS Google Scholar Goyal A, Bhat M, Sharma M, Garg M, Khairwa A, Garg R. Article PubMed Google Scholar Gulati A, Rajkumar S, Karthigeyan S, Sud RK, Vijayan D, Thomas J, et al. Article CAS PubMed Google Scholar Han S, Kim E, Hwang K, Ratan Z, Hwang H, Kim E-M, et al. Article PubMed Central CAS Google Scholar Hernández-Hernández C, Morales-Sillero A, Fernández-Bolaños J, Bermúdez-Oria A, Morales AA, Rodríguez-Gutiérrez G. Article PubMed CAS Google Scholar Huang CC, Wu WB, Fang JY, Chiang HS, Chen SK, Chen BH, Chen YT, Hung CF. Article CAS PubMed PubMed Central Google Scholar Ide K, Yamada H, Matsushita K, Ito M, Nojiri K, Toyoizumi K, et al. Article PubMed PubMed Central CAS Google Scholar Im KM, Jeon J-R. Google Scholar Iñiguez-Franco F, Soto-Valdez H, Peralta E, Ayala-Zavala JF, Auras R, Gámez-Meza N. Article PubMed CAS Google Scholar Jackson JK, Zhao J, Wong W, Burt HM. Article CAS PubMed Google Scholar Jang J-H, Park Y-D, Ahn H-K, Kim S-J, Lee J-Y, Kim E-C, et al. Article CAS Google Scholar Jeon J-R, Kim E-J, Murugesan K, Park H-K, Kim Y-M, Kwon J-H, et al. Article CAS PubMed PubMed Central Google Scholar Jin Y, Jin CH, Ho RK. Article CAS PubMed Google Scholar Kadhum WR, Sekiguchi S, Hijikuro I, Todo H, Sugibayashi K. Article CAS PubMed Google Scholar Kim E, Hwang K, Lee J, Han S, Kim E-M, Park J, et al. Article PubMed CAS Google Scholar Kim M-M. Article PubMed Google Scholar Kim SS, Hyun C-G, Choi YH, Lee NH. Article PubMed CAS Google Scholar Kim YC, Choi SY, Park EY. Article PubMed PubMed Central Google Scholar Klein T, Longhini R, de Mello JCP. Article CAS PubMed Google Scholar Kosińska A, Karamać M, Estrella I, Hernández T, Bartolomé B, Dykes GA. Article PubMed CAS Google Scholar Kumar M, Chandel M, Kaur P, Pandit K, Kaur V, Kaur S, et al. PubMed PubMed Central Google Scholar Li C, Seeram NP. Article CAS PubMed PubMed Central Google Scholar Lima EBC, de Sousa CNS, Vasconcelos GS, Meneses LN, YF e SP, Ximenes NC, et al. Article PubMed Google Scholar Madhan B, Subramanian V, Rao JR, Nair BU, Ramasami T. Article CAS PubMed Google Scholar Magalhães AC, Wiegand A, Rios D, Hannas A, Attin T, Buzalaf MAR. Article PubMed CAS Google Scholar Magalhães LM, Machado S, Segundo MA, Lopes JA, Páscoa RNMJ. Article PubMed CAS Google Scholar Marques TR, Cesar PHS, Braga MA, Marcussi S, Corrêa AD. Article CAS PubMed Google Scholar Martincigh BS, Ollengo MA. Article CAS PubMed Google Scholar Matsubara T, Wataoka I, Urakawa H, Yasunaga H. Article CAS PubMed Google Scholar Moulton MC, Braydich-Stolle LK, Nadagouda MN, Kunzelman S, Hussain SM, Varma RS. Article CAS PubMed Google Scholar Muhammad D, Hubert J, Lalun N, Renault J-H, Bobichon H, Nour M, et al. Article PubMed CAS Google Scholar Nadim M, Auriol D, Lamerant-FayeL N, Lefèvre F, Dubanet L, Redziniak G, et al. Article CAS PubMed Google Scholar Niu L, Shao M, Liu Y, Hu J, Li R, Xie H, et al. Article CAS PubMed Google Scholar Ohmori Y, Ito M, Kishi M, Mizutani H, Katada T, Konishi H. Article CAS PubMed Google Scholar Oliveira MB, Valentim IB, de Vasconcelos CC, Omena CM, Bechara EJ, da Costa JG, Freitas Mde L, Sant'Ana AE, Goulart MO. CAS PubMed Google Scholar Ow Y-Y, Stupans I. Article CAS PubMed Google Scholar Parisi OI, Puoci F, Iemma F, Curcio M, Cirillo G, Spizzirri UG, et al. Article PubMed CAS Google Scholar Puri A, Nguyen HX, Banga AK. Article CAS PubMed Google Scholar Reis GM, Faccin H, Viana C, da Rosa MB, de Carvalho LM. Article CAS PubMed Google Scholar Rojas LB, Quideau S, Pardon P, Charrouf Z. Article CAS PubMed Google Scholar Scalia S, Marchetti N, Bianchi A. Article CAS PubMed PubMed Central Google Scholar Sharma A, Gupta P, Verma AK. Article PubMed PubMed Central CAS Google Scholar Shi M, Nie Y, Zheng X-Q, Lu J-L, Liang Y-R, Ye J-H. Article PubMed Central CAS Google Scholar Shin MC, Park SK, Jung SH. Article CAS PubMed Google Scholar Shoko T, Maharaj VJ, Naidoo D, Tselanyane M, Nthambeleni R, Khorombi E, et al. Article PubMed PubMed Central CAS Google Scholar Sidgwick GP, McGeorge D, Bayat A. Article CAS PubMed PubMed Central Google Scholar Singh BN, Shankar S, Srivastava RK. Article CAS PubMed PubMed Central Google Scholar Skowyra M, Falguera V, Gallego G, Peiró S, Almajano MP. Article PubMed CAS Google Scholar Spizzirri UG, Iemma F, Puoci F, Cirillo G, Curcio M, Parisi OI, et al. Article CAS PubMed Google Scholar Takahashi T, Yokoo Y, Inoue T, Ishii A. Article CAS PubMed Google Scholar Tsuchiya H, Sato M, Kato H, Okubo T, Juneja LR, Kim M. Article CAS PubMed Google Scholar Wisuitiprot W, Somsiri A, Ingkaninan K, Waranuch N. Article CAS PubMed Google Scholar Xia J, Song X, Bi Z, Chu W, Wan Y. CAS PubMed Google Scholar Yang W, Liu F, Xu C, Sun C, Yuan F, Gao Y. Article CAS PubMed Google Scholar Yang W, Xu C, Liu F, Sun C, Yuan F, Gao Y. Article CAS PubMed Google Scholar Yang W, Yuan F, Gao YX. CAS PubMed Google Scholar Yoshino S, Mitoma T, Tsuruta K, Todo H, Sugibayashi K. Article PubMed CAS Google Scholar Yuki K, Ikeda N, Nishiyama N, Kasamatsu T. Article CAS PubMed Google Scholar Zhang W, Yang Y, Lv T, Fan Z, Xu Y, Yin J, et al. Article PubMed CAS Google Scholar Zhong Y, Shahidi F. Article CAS PubMed Google Scholar Zillich OV, Schweiggert-Weisz U, Eisner P, Kerscher M. Article CAS PubMed Google Scholar Zillich OV, Schweiggert-Weisz U, Hasenkopf K, Eisner P, Kerscher M. Article CAS PubMed Google Scholar Download references. Acknowledgements We would like to thank Yeoju-si and Yeoju Institute of Technology Gyeonggi-do, Republic of Korea for their support for this study. Funding Not applicable. Author information Author notes Joonseo Bae, Nayoung Kim and Yunyoung Shin contributed equally to this work. |
| The roles of catechins in regulation of systemic inflammation | Food Science and Biotechnology | Online ISSN : Print ISSN : ISSN-L : 資料トップ 早期公開 巻号一覧 おすすめ記事 この資料について. Neuroprotective Effects of the Green Tea Components Theanine and Catechins. Takami Kakuda 著者情報. Takami Kakuda Central Research Institute, Itoen, Ltd. 責任著者 Corresponding author. キーワード: tea , theanine , catechin , neuroprotection , glutamate receptor. ジャーナル フリー. PDFをダウンロード K メタデータをダウンロード RIS形式 EndNote、Reference Manager、ProCite、RefWorksとの互換性あり. 引用文献 関連文献 0. 電子付録 0. You may want to consider making green tea a regular part of your lifestyle in a way that meets your personal health goals and taste preferences. Read this article in Spanish. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. VIEW ALL HISTORY. Green tea extract is a concentrated supplemental form of green tea. Here are 10 science-based benefits of green tea extract. Drinking lemon and green tea together is a great way to get the health benefits of these two ingredients. Matcha is a type of powdered green tea. It is very high in antioxidants and has numerous health benefits for your body and brain. Matcha comes from the same plant as green tea, but it contains more antioxidants and caffeine. Here are 7 possible health benefits of matcha tea…. While they're not typically able to prescribe, nutritionists can still benefits your overall health. Let's look at benefits, limitations, and more. A new study found that healthy lifestyle choices — including being physically active, eating well, avoiding smoking and limiting alcohol consumption —…. Carb counting is complicated. Take the quiz and test your knowledge! Together with her husband, Kansas City Chiefs MVP quarterback Patrick Mahomes, Brittany Mohomes shares how she parents two children with severe food…. While there are many FDA-approved emulsifiers, European associations have marked them as being of possible concern. Let's look deeper:. Researchers have found that a daily multivitamin supplement was linked with slowed cognitive aging and improved memory. A Quiz for Teens Are You a Workaholic? How Well Do You Sleep? Health Conditions Discover Plan Connect. Nutrition Evidence Based 10 Evidence-Based Benefits of Green Tea. Medically reviewed by Kathy W. Warwick, R. Contains plant-based antioxidant compounds. May improve cognitive function. Could help with fat burning. Might lower the risk of some cancers. May protect the brain from aging. Could help with oral health. May help with the managing blood sugar. Explore our top resources. Might help prevent heart disease. May help you lose weight. Might help you live longer. Frequently asked questions. The bottom line. How we reviewed this article: Sources. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Dec 6, Written By Kris Gunnars, Dylan Bailey, MS, RD, FAND. Sep 14, Medically Reviewed By Kathy Warwick, RD, LD. Share this article. Read this next. By Arlene Semeco, MS, RD and Alyssa Northrop, MPH, RD, LMT. By Rachael Ajmera, MS, RD. Matcha — Even More Powerful Than Regular Green Tea? By Adda Bjarnadottir, MS, RDN Ice. How Nutritionists Can Help You Manage Your Health. Healthy Lifestyle May Offset Cognitive Decline Even in People With Dementia A new study found that healthy lifestyle choices — including being physically active, eating well, avoiding smoking and limiting alcohol consumption —… READ MORE. Quiz: How Much Do You Know About Carb Counting? |
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