Category: Children

Polyphenols and memory enhancement

Polyphenols and memory enhancement

a Value Weight loss supplements for athletes LOQ. Effects of soy isoflavone supplementation Polyphebols cognitive function in Chinese postmenopausal memoru a double-blind, randomized, controlled trial. Neurodegeneration Polyphenolw streptozotocin-induced diabetic rats Inflammation and overall wellness attenuated by treatment enhancemnt Natural solutions for high blood pressure. Polpyhenols grape juice by Enhancemenf Foods, Inc supplementation was reported to improve spatial memory and driving performance in middle-aged working mothers 79 and memory function in older adults with MCI 80 Chocolate intake is associated with better cognitive function: The Maine-Syracuse Longitudinal Study. Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging CoCoA study—a randomized controlled trial. Food combination and Alzheimer disease risk: a protective diet. Polyphenols and memory enhancement

Polyphenols and memory enhancement -

El Mohsen MA, Marks J, Kuhnle G et al Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats.

Br J Nutr — Pharmacol Res — Fehske CJ, Leuner K, Muller WE Ginkgo biloba extract EGb influences monoaminergic neurotransmission via inhibition of NE uptake, but not MAO activity after chronic treatment.

J Alzheimers Dis — Forsythe P, Sudo N, Dinan T et al Mood and gut feelings. Brain Behav Immun — Francis ST, Head K, Morris PG et al The effect of flavanol-rich cocoa on the fMRI response to a cognitive task in healthy young people. J Cardiovasc Pharmacol 47 Suppl 2 :S—SS PubMed Google Scholar.

Friden M, Ljungqvist H, Middleton B et al Improved measurement of drug exposure in the brain using drug-specific correction for residual blood. J Cereb Blood Flow Metab — Ghosh D, Scheepens A Vascular action of polyphenols.

Mol Nutr Food Res — Grassi D, Mulder TP, Draijer R et al Black tea consumption dose-dependently improves flow-mediated dilation in healthy males. J Hypertens — Gruber J, Tang SY, Halliwell B Evidence for a trade-off between survival and fitness caused by resveratrol treatment of Caenorhabditis elegans.

Haberichter T, Marhl M, Heinrich R Birhythmicity, trirhythmicity and chaos in bursting calcium oscillations. Biophys Chem — Halliwell B Oxidative stress in cell culture: an under-appreciated problem?

FEBS Lett —6. Halliwell B Oxidative stress and neurodegeneration: where are we now? J Neurochem — Halliwell B a Dietary polyphenols: good, bad, or indifferent for your health?

Cardiovasc Res — Halliwell B b Flavonoids: a re-run of the carotenoids story? Novartis Found Symp — discussion , — Halliwell B, Gutteridge J Free radicals in biology and medicine. Oxford University Press, Oxford. Halliwell B, Zhao K, Whiteman M The gastrointestinal tract: a major site of antioxidant action?

Free Radic Res — Halliwell B, Rafter J, Jenner A Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not? Am J Clin Nutr S—S. Hanrahan JR, Chebib M, Johnston GA Flavonoid modulation of GABA A receptors.

Br J Pharmacol — Heijtz RD, Wang S, Anuar F et al Normal gut microbiota modulates brain development and behavior. Proc Natl Acad Sci USA — Heiss C, Finis D, Kleinbongard P et al Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week.

J Cardiovasc Pharmacol — Heiss C, Jahn S, Taylor M et al Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.

J Am Coll Cardiol — Hollman PC, Cassidy A, Comte B et al The biological relevance of direct antioxidant effects of polyphenols for cardiovascular health in humans is not established. J Nutr S—S. Hu M Commentary: bioavailability of flavonoids and polyphenols: call to arms. Mol Pharm — Ishisaka A, Ichikawa S, Sakakibara H et al Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats.

Jager AK, Saaby L Flavonoids and the CNS. Molecules — Janle EM, Lila MA, Grannan M et al Pharmacokinetics and tissue distribution of 14C-labeled grape polyphenols in the periphery and the central nervous system following oral administration.

J Med Food — Jenner AM, Rafter J, Halliwell B Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds. Kanner J, Lapidot T The stomach as a bioreactor: dietary lipid peroxidation in the gastric fluid and the effects of plant-derived antioxidants.

Kelly RP, Poo YK, Isaac HB et al Lack of effect of acute oral ingestion of vitamin C on oxidative stress, arterial stiffness or blood pressure in healthy subjects. Lau FC, Shukitt-Hale B, Joseph JA The beneficial effects of fruit polyphenols on brain aging. Neurobiol Aging 26 Suppl 1 — Lee CY, Isaac HB, Huang SH et al Limited antioxidant effect after consumption of a single dose of tomato sauce by young males, despite a rise in plasma lycopene.

Lekakis J, Rallidis LS, Andreadou I et al Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease. Eur J Cardiovasc Prev Rehabil — Lemberger T Systems biology in human health and disease.

Mol Syst Biol Letenneur L, Proust-Lima C, Le Gouge A et al Flavonoid intake and cognitive decline over a year period. Am J Epidemiol — J Biol Chem — Long LH, Halliwell B Artefacts in cell culture: pyruvate as a scavenger of hydrogen peroxide generated by ascorbate or epigallocatechin gallate in cell culture media.

Long LH, Halliwell B Artefacts in cell culture: alpha-Ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media. Long LH, Hoi A, Halliwell B Instability of, and generation of hydrogen peroxide by, phenolic compounds in cell culture media.

Arch Biochem Biophys — Lotito SB, Frei B Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Lykkesfeldt J, Trueba GP, Poulsen HE et al Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain.

Macready AL, Kennedy OB, Ellis JA et al Flavonoids and cognitive function: a review of human randomized controlled trial studies and recommendations for future studies.

Genes Nutr — Maher P, Akaishi T, Abe K Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory. Manach C, Scalbert A, Morand C et al Polyphenols: food sources and bioavailability.

Am J Clin Nutr — Mattson MP, Cheng A Neurohormetic phytochemicals: low-dose toxins that induce adaptive neuronal stress responses.

Trends Neurosci — Montero M, Lobaton CD, Hernandez-Sanmiguel E et al Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids. Biochem J — Muller WE, Singer A, Wonnemann M et al Hyperforin represents the neurotransmitter reuptake inhibiting constituent of hypericum extract.

Pharmacopsychiatry 31 Suppl 1 — J Nutr Sci Vitaminol Tokyo — Article CAS Google Scholar. Nurk E, Refsum H, Drevon CA et al Intake of flavonoid-rich wine, tea, and chocolate by elderly men and women is associated with better cognitive test performance.

Ofir R, Tamir S, Khatib S et al Inhibition of serotonin re-uptake by licorice constituents. J Mol Neurosci — Pan MH, Huang TM, Lin JK Biotransformation of curcumin through reduction and glucuronidation in mice.

Drug Metab Dispos — Pannala AS, Rice-Evans CA, Halliwell B et al Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols. Peng HW, Cheng FC, Huang YT et al Determination of naringenin and its glucuronide conjugate in rat plasma and brain tissue by high-performance liquid chromatography.

J Chromatogr B Biomed Sci Appl — Pietsch K, Saul N, Chakrabarti S et al Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. Biogerontology — Prasain JK, Peng N, Dai Y et al Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extract.

Phytomedicine — Purkayastha S, Berliner A, Fernando SS et al Curcumin blocks brain tumor formation. Brain Res — Quinn JF, Raman R, Thomas RG et al Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial.

JAMA — Racagni G, Popoli M The pharmacological properties of antidepressants. Int Clin Psychopharmacol — Reiter RJ Oxidative processes and antioxidative defense mechanisms in the aging brain.

FASEB J — Rhee SH, Pothoulakis C, Mayer EA Principles and clinical implications of the brain-gut-enteric microbiota axis.

Nat Rev Gastroenterol Hepatol — Rice ME Ascorbate regulation and its neuroprotective role in the brain. Rice-Evans CA, Miller NJ, Bolwell PG et al The relative antioxidant activities of plant-derived polyphenolic flavonoids.

Rocha FF, Lima-Landman MT, Souccar C et al Antidepressant-like effect of Cecropia glazioui Sneth and its constituents—in vivo and in vitro characterization of the underlying mechanism. Russo A, Acquaviva R, Campisi A et al Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors.

Cell Biol Toxicol — Ryan J, Croft K, Mori T et al An examination of the effects of the antioxidant pycnogenol on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population. J Psychopharmacol — J Agric Food Chem — Schaffer S, Eckert GP, Muller WE et al Hypochlorous acid scavenging properties of local Mediterranean plant foods.

Lipids — Schaffer S, Eckert GP, Schmitt-Schillig S et al Plant foods and brain aging: a critical appraisal. Forum Nutr — Schumann K, Szegner B, Kohler B et al A method to assess 59Fe in residual tissue blood content in mice and its use to correct 59Fe-distribution kinetics accordingly.

Toxicology — Spear LP, Varlinskaya EI Low dose effects in psychopharmacology: ontogenetic considerations. Nonlinearity Biol Toxicol Med — Spencer JP The interactions of flavonoids within neuronal signalling pathways. Spencer JP Flavonoids: modulators of brain function.

Br J Nutr 99 E Suppl 1 :ES60—ES Spencer JP Flavonoids and brain health: multiple effects underpinned by common mechanisms. Spencer JP, Abd-el-Mohsen MM, Rice-Evans C Cellular uptake and metabolism of flavonoids and their metabolites: implications for their bioactivity.

Sun F, Iwaguchi K, Shudo R et al Change in tissue concentrations of lipid hydroperoxides, vitamin C and vitamin E in rats with streptozotocin-induced diabetes. Clin Sci Lond — Talavera S, Felgines C, Texier O et al Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain.

Terpstra M, Torkelson C, Emir U et al Noninvasive quantification of human brain antioxidant concentrations after an intravenous bolus of vitamin C.

NMR Biomed — Trzeciakowski J, Chilian WM Chaotic behavior of the coronary circulation. Med Biol Eng Comput — J Pharmacol Exp Ther — van Duynhoven J, Vaughan EE, Jacobs DM et al Metabolic fate of polyphenols in the human superorganism.

Proc Natl Acad Sci USA Suppl 1 — van Mierlo LA, Zock PL, van der Knaap HC et al Grape polyphenols do not affect vascular function in healthy men. Visioli F, Bellomo G, Galli C Free radical-scavenging properties of olive oil polyphenols. Visioli F, de la Lastra CA, Andres-Lacueva C et al Polyphenols and human health: a prospectus.

Crit Rev Food Sci Nutr — Wagner AE, Boesch-Saadatmandi C, Breckwoldt D et al Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes—role of the redox-regulated transcription factor Nrf2.

BMC Compl Altern Med CAS Google Scholar. Watjen W, Michels G, Steffan B et al Low concentrations of flavonoids are protective in rat H4IIE cells whereas high concentrations cause DNA damage and apoptosis. Wehner F, Lawonn P, Tinel H Ionic mechanisms of regulatory volume increase RVI in the human hepatoma cell-line HepG2.

Pflugers Arch — Wilkinson AP, Wahala K, Williamson G Identification and quantification of polyphenol phytoestrogens in foods and human biological fluids. J Chromatogr B Analyt Technol Biomed Life Sci — Yanez M, Fraiz N, Cano E et al Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity.

Yokomizo A, Moriwaki M Effects of uptake of flavonoids on oxidative stress induced by hydrogen peroxide in human intestinal Caco-2 cells. Biosci Biotechnol Biochem — Yoshitake T, Yoshitake S, Kehr J The Ginkgo biloba extract EGb R and its main constituent flavonoids and ginkgolides increase extracellular dopamine levels in the rat prefrontal cortex.

Youdim KA, Shukitt-Hale B, Joseph JA Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system.

Alzheimers Dement. Park DC, Reuter-Lorenz P. The adaptive brain: aging and neurocognitive scaffolding. Annu Rev Psychol. Peters R. Ageing and the brain. Postgrad Med J. Ahles S, Stevens YR, Joris PJ, Vauzour D, Adam J, de Groot E, et al.

The effect of long-term aronia melanocarpa extract supplementation on cognitive performance, mood, and vascular function: a randomized controlled trial in healthy, middle-aged individuals. Basaria S, Wisniewski A, Dupree K, Bruno T, Song MY, Yao F, et al. Effect of high-dose isoflavones on cognition, quality of life, androgens, and lipoprotein in post-menopausal women.

J Endocrinol Invest. Beck SM, Ruge H, Schindler C, Burkart M, Miller R, Kirschbaum C, et al. Effects of Ginkgo biloba extract EGb R on cognitive control functions, mental activity of the prefrontal cortex and stress reactivity in elderly adults with subjective memory impairment - a randomized double-blind placebo-controlled trial.

Hum Psychopharmacol. Bensalem J, Dudonné S, Etchamendy N, Pellay H, Amadieu C, Gaudout D, et al. Polyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: a bicentric double-blind, randomized, placebo-controlled clinical study.

J Gerontol Ser A Biol Sci Med Sci. Burns NR, Bryan J, Nettelbeck T. Ginkgo biloba: no robust effect on cognitive abilities or mood in healthy young or older adults. Carlson JJ, Farquhar JW, DiNucci E, Ausserer L, Zehnder J, Miller D, et al. Safety and efficacy of a ginkgo biloba-containing dietary supplement on cognitive function, quality of life, and platelet function in healthy, cognitively intact older adults.

J Am Diet Assoc. Casini ML, Marelli G, Papaleo E, Ferrari A, D'Ambrosio F, Unfer V. Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo-controlled study.

Fertil Steril. Cieza A, Maier P, Pöppel E. Effects of Ginkgo biloba on mental functioning in healthy volunteers. Arch Med Res. Cox KHM, White DJ, Pipingas A, Poorun K, Scholey A. Further evidence of benefits to mood and working memory from lipidated curcumin in healthy older people: a week, double-blind, placebo-controlled, partial replication study.

Desideri G, Kwik-Uribe C, Grassi D, Necozione S, Ghiadoni L, Mastroiacovo D, et al. Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment the cocoa, cognition, and aging CoCoA study.

Dodge HH, Zitzelberger T, Oken BS, Howieson D, Kaye J. A randomized placebo-controlled trial of Ginkgo biloba for the prevention of cognitive decline. Evans HM, Howe PRC, Wong RHX.

Effects of resveratrol on cognitive performance, mood and cerebrovascular function in post-menopausal women; a week randomised placebo-controlled intervention trial. Fournier LR, Ryan Borchers TA, Robison LM, Wiediger M, Park JS, Chew BP, et al. The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women.

J Nutr Health Aging. Furlong ON, Parr HJ, Hodge SJ, Slevin MM, Simpson EE, McSorley EM, et al. Consumption of a soy drink has no effect on cognitive function but may alleviate vasomotor symptoms in post-menopausal women; a randomised trial.

Gavrilova SI, Preuss UW, Wong JW, Hoerr R, Kaschel R, Bachinskaya N, et al. Efficacy and safety of Ginkgo biloba extract EGb in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial. Int J Geriatr Psychiatry.

Gleason CE, Fischer BL, Dowling NM, Setchell KD, Atwood CS, Carlsson CM, et al. Cognitive effects of soy isoflavones in patients with Alzheimer's disease. Hartley DE, Elsabagh S, File SE.

Gincosan a combination of Ginkgo biloba and Panax ginseng : the effects on mood and cognition of 6 and 12 weeks' treatment in post-menopausal women.

Nutr Neurosci. Herrlinger KA, Nieman KM, Sanoshy KD, Fonseca BA, Lasrado JA, Schild AL, et al. Spearmint extract improves working memory in men and women with age-associated memory impairment. J Altern Complement Med. Herrschaft H, Nacu A, Likhachev S, Sholomov I, Hoerr R, Schlaefke S.

Ginkgo biloba extract EGb R in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of mg. J Psychiatr Res. Ho SC, Chan ASY, Ho YP, So EKF, Sham A, Zee B, et al. Effects of soy isoflavone supplementation on cognitive function in Chinese postmenopausal women: a double-blind, randomized, controlled trial.

Huhn S, Beyer F, Zhang R, Lampe L, Grothe J, Kratzsch J, et al. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - a randomized controlled trial.

Jackson PA, Forster JS, Bell JG, Dick JR, Younger I, Kennedy DO. DHA supplementation alone or in combination with other nutrients does not modulate cerebral hemodynamics or cognitive function in healthy older adults. Kanowski S, Herrmann WM, Stephan K, Wierich W, Horr R.

Proof of efficacy of the ginkgo biloba special extract EGb in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Kaschel R. Specific memory effects of Ginkgo biloba extract EGb in middle-aged healthy volunteers.

Kean RJ, Lamport DJ, Dodd GF, Freeman JE, Williams CM, Ellis JA, et al. Chronic consumption of flavanone-rich orange juice is associated with cognitive benefits: an 8-wk, randomized, double-blind, placebo-controlled trial in healthy older adults. Am J Clin Nutr. Kreijkamp-Kaspers S, Kok L, Grobbee DE, de Haan EHF, Aleman A, Lampe JW, et al.

Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women - a randomized controlled trial. Kritz-Silverstein D, Von Muhlen D, Barrett-Connor E, Bressel MAB.

Isoflavones and cognitive function in older women: the soy and postmenopausal health in aging SOPHIA study. Kuszewski JC, Howe PRC, Wong RHX.

Evaluation of cognitive performance following fish-oil and curcumin supplementation in middle-aged and older adults with overweight or obesity.

J Nutr. Le Bars PL, Katz MM, Berman N, Itil TM, Freedman AM, Schatzberg AF. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia.

North American EGb Study Group. Lewis JE, Melillo AB, Tiozzo E, Chen L, Leonard S, Howell M, et al. A double-blind, randomized clinical trial of dietary supplementation on cognitive and immune functioning in healthy older adults.

Li S, Cao GY, Deng QW, Zhu D, Yan FL. Effect of Pushen capsule for treating vascular mild cognitive impairment: a pilot observational study.

J Int Med Res. Mastroiacovo D, Kwik-Uribe C, Grassi D, Necozione S, Raffaele A, Pistacchio L, et al. Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging CoCoA study—a randomized controlled trial.

Mazza M, Capuano A, Bria P, Mazza S. Ginkgo biloba and donepezil: a comparison in the treatment of Alzheimer's dementia in a randomized placebo-controlled double-blind study. Eur J Neurol. McCarney R, Fisher P, Iliffe S, van Haselen R, Griffin M, van der Meulen J, et al.

Ginkgo biloba for mild to moderate dementia in a community setting: a pragmatic, randomised, parallel-group, double-blind, placebo-controlled trial. McNamara RK, Kalt W, Shidler MD, McDonald J, Summerc SS, Stein AL, et al. Cognitive response to fish oil, blueberry, and combined supplementation in older adults with subjective cognitive impairment.

Neurobiol Aging. Mix JA, Crews WD. An examination of the efficacy of Ginkgo biloba extract EGb on the neuropsychologic functioning of cognitively intact older adults. Napryeyenko O, Borzenko I, Group G-NS. Ginkgo biloba special extract in dementia with neuropsychiatric features.

A randomised, placebo-controlled, double-blind clinical trial. Nasab NM, Bahrammi MA, Nikpour MRA, Rahim F, Naghibi SN. Efficacy of rivastigmine in comparison to ginkgo for treating Alzheimer's dementia. Nilsson A, Salo I, Plaza M, Bjorck I.

Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults. Plos One. Ochiai R, Saitou K, Suzukamo C, Osaki N, Asada T.

Effect of chlorogenic acids on cognitive function in mild cognitive impairment: a randomized controlled crossover trial. J Alzheimers Dis. Pase MP, Scholey AB, Pipingas A, Kras M, Nolidin K, Gibbs A, et al. Cocoa polyphenols enhance positive mood states but not cognitive performance: a randomized, placebo-controlled trial.

Pipingas A, Silberstein RB, L Vitetta, C Rooy, Van Harris EV, Young JM, et al. Improved cognitive performance after dietary supplementation with a Pinus radiata bark extract formulation.

Phytother Res. Rainey-Smith SR, Brown BM, Sohrabi HR, Shah T, Goozee KG, Gupta VB, et al. Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults. Br J Nutr. Ryan J, Croft K, Mori T, Wesnes K, Spong J, Downey L, et al.

An examination of the effects of the antioxidant Pycnogenol R on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population. Santos RF, Galduroz JCF, Barbieri A, Castiglioni MLV, Ytaya LY, Bueno OFA.

Cognitive performance, SPECT, and blood viscosity in elderly non-demented people using Ginkgo biloba. Schneider LS, DeKosky ST, Farlow MR, Tariot PN, Hoerr R, Kieser MA. Randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type.

Curr Alzheimer Res. Schneider LS, Hernandez G, Zhao L, Franke AA, Chen YL, Pawluczyk S, et al. Siddarth P, Li ZP, Miller KJ, Ercoli LM, Merril DA, Henning SM, et al. Randomized placebo-controlled study of the memory effects of pomegranate juice in middle-aged and older adults.

Small BJ, Rawson KS, Martin C, Eisel SL, Sanberg CD, McEvoy CL, et al. Nutraceutical intervention improves older adults' cognitive functioning.

Rejuvenation Res. Snitz BE, O'Meara ES, Carlson MC, Arnold AM, Ives DG, Rapp SR, et al. Ginkgo biloba for preventing cognitive decline in older adults a randomized trial. Solomon PR, Adams F, Silver A, Zimmer J, DeVeaux R. Ginkgo for memory enhancement - a randomized controlled trial.

Suominen MH, Laaksonen MML, Salmenius-Suominen H, Kautiainen H, Hongisto SM, Tuukkanen K, et al. The short-term effect of dark chocolate flavanols on cognition in older adults: a randomized controlled trial FlaSeCo. Exp Gerontol. Thaung Zaw JJ, Howe PR, Wong RH.

Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: a month randomised, double-blind, placebo-controlled, crossover study.

Clin Nutr. van Dongen MCJM, van Rossum E, Kessels AGH, Sielhorst HJG, Knipschild PG. The efficacy of ginkgo for elderly people with dementia and age-associated memory impairment: new results of a randomized clinical trial.

J Am Geriatr Soc. Whyte AR, Cheng N, Fromentin E, Williams CM. A randomized, double-blinded, placebo-controlled study to compare the safety and efficacy of low dose enhanced wild blueberry powder and wild blueberry extract think blue in maintenance of episodic and working memory in older adults.

Wightman EL, Jackson PA, Khan J, Forster J, Heiner F, Feistel B, et al. The acute and chronic cognitive and cerebral blood flow effects of a sideritis scardica greek mountain tea extract: a double blind, randomized, placebo controlled, parallel groups study in healthy humans.

Witte AV, Kerti L, Margulies DS, Floel A. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults. J Neurosci.

Wong RHX, Berry NM, Coates AM, Buckley JD, Bryan J, Kunz I, et al. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults. J Hypertens.

Woo J, Lau E, Ho SC, Cheng F, Chan C, Chan ASY, et al. Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause. Yakoot M, Salem A, Helmy S. Effect of memo R , a natural formula combination, on mini-mental state Examination scores in patients with mild cognitive impairment.

Clin Interv Aging. Yancheva S, Ihl R, Nikolova G, Panayotov P, Schlaefke S, Hoerr R, et al. Ginkgo biloba extract EGb , donepezil or both combined in the treatment of Alzheimer's disease with neuropsychiatric features: a randomised, double-blind, exploratory trial.

Aging Ment Health. You YX, Shahar S, Rajab NF, Haron H, Yahya HM, Mohamad M, et al. Effects of 12 weeks cosmos caudatus supplement among older adults with mild cognitive impairment: a randomized, double-blind and placebo-controlled trial. Zhang SJ, Xue ZY. Effect of Western medicine therapy assisted by Ginkgo biloba tablet on vascular cognitive impairment of none dementia.

Asian Pac J Trop Med. JASP Team. JASP Version 0. An overview on dietary polyphenols and their biopharmaceutical classification system BCS. Int J Mol Sci.

Cheng PF, Chen JJ, Zhou XY, Ren YF, Huang W, Zhou JJ, et al. Do soy isoflavones improve cognitive function in postmenopausal women? A meta-analysis.

File SE, Jarrett N, Fluck E, Duffy R, Casey K, Wiseman H. Eating soya improves human memory. Brickman AM, Khan UA, Provenzano FA, Yeung LK, Suzuki W, Schroeter H, et al.

Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults. Nat Neurosci. Ezzyat Y, Olson IR. The medial temporal lobe and visual working memory: comparisons across tasks, delays, and visual similarity. Cogn Affect Behav Neurosci.

Braun M, Weinrich C, Finke C, Ostendorf F, Lehmann T-N, Ploner CJ. Lesions affecting the right hippocampal formation differentially impair short-term memory of spatial and nonspatial associations.

Hannula DE, Tranel D, Cohen NJ. The long and the short of it: relational memory impairments in amnesia, even at short lags. Kesse-Guyot E, Fezeu L, Andreeva VA, Touvier M, Scalbert A, Hercberg S, et al.

Total and specific polyphenol intakes in midlife are associated with cognitive function measured 13 years later. Slopien R, Wender-Ozegowska E, Rogowicz-Frontczak A, Meczekalski B, Zozulinska-Ziolkiewicz D, Jaremek JD, et al. Menopause and diabetes: EMAS clinical guide. Cell — New pharmacological strategies for cognitive enhancement using a rat model of age-related memory impairment.

Ann N Y Acad Sci 16— Age-related cognitive impairment as a sign of geriatric neurocardiovascular interactions: may polyphenols play a protective role?

Oxid Med Cell Longev Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. J Nutr — Relative impact of flavonoid composition, dose and structure on vascular function: a systematic review of randomised controlled trials of flavonoid-rich food products.

Mol Nutr Food Res — Total and specific polyphenol intakes in midlife are associated with cognitive function measured 13 years later. J Nutr 76— Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr — Blueberry supplementation improves memory in older adults.

J Agric Food Chem — A high-cholesterol diet enriched with polyphenols from Oriental plums Prunus salicina improves cognitive function and lowers brain cholesterol levels and neurodegenerative-related protein expression in mice. The effect of flavanol-rich cocoa on cerebral perfusion in healthy older adults during conscious resting state: a placebo controlled, crossover, acute trial.

Psychopharmacology Berl — The effects of flavanone-rich citrus juice on cognitive function and cerebral blood flow: an acute, randomised, placebo-controlled cross-over trial in healthy, young adults.

Flavonoid intake and cognitive decline over a year period. Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta oligomers and upregulating synaptic plasticity-related proteins in the hippocampus.

Fruit, vegetables and prevention of cognitive decline or dementia: a systematic review of cohort studies. J Nutr Health Aging — Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies.

Nutr Res Rev — Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate EGCG.

Neuroinflammation and anti-inflammatory therapy for Alzheimer's disease. Adv Drug Deliv Rev — Tannic acid is a natural beta-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.

J Biol Chem 9 : — Associations of vegetable and fruit consumption with age-related cognitive change. The ageing cortical synapse: hallmarks and implications for cognitive decline.

Nat Rev Neurosci — Acetylcholine, aging, and Alzheimer's disease. Pharmacol Biochem Behav — High-flavonoid intake induces cognitive improvements linked to changes in serum brain-derived neurotrophic factor: two randomised, controlled trials. Nutr Healthy Aging 4: 81— Phenol-Explorer: an online comprehensive database on polyphenol contents in foods.

Database Oxford bap Fruit and vegetable intake and cognitive decline in middle-aged men and women: the Doetinchem Cohort Study. Intake of flavonoid-rich wine, tea, and chocolate by elderly men and women is associated with better cognitive test performance.

Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity. J Biol Chem — Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols.

Biochem Biophys Res Commun — Novel role of red wine-derived polyphenols in the prevention of Alzheimer's disease dementia and brain pathology: experimental approaches and clinical implications.

Planta Med 78 15 : — Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment. Biochim Biophys Acta — Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats.

Pharmacol Res — Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor.

PLoS One 8: e Green tea epigallocatechingallate EGCG reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice. Brain Res — Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update.

Arch Toxicol — Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors. Cell Biol Toxicol 91— Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort.

J Psychopharmacol — Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase JNK , c-Jun and caspase Biochem J — Proc Natl Acad Sci USA — Psychomotor and spatial memory performance in aging male Fischer rats.

Exp Gerontol — Is there anything special about the aging of source memory? Psychol Aging 19— Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am J Clin Nutr — Diet and Alzheimer's disease risk factors or prevention: the current evidence.

Expert Rev Neurother — Cerebral blood flow response to flavanol-rich cocoa in healthy elderly humans. Neuropsychiatr Dis Treat 4: — The impact of flavonoids on memory: physiological and molecular considerations. Chem Soc Rev — Flavonoids and cognition: the molecular mechanisms underlying their behavioural effects.

Arch Biochem Biophys 1—9. Impact of diet on adult hippocampal neurogenesis. Genes Nutr 4: — Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population. Targeting the CREB pathway for memory enhancers.

Nat Rev Drug Discov 2: — J Neurosci — Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects.

Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology. J Sci Food Agric — Champagne wine polyphenols protect primary cortical neurons against peroxynitrite-induced injury.

The neuroprotective potential of flavonoids: a multiplicity of effects. Genes Nutr 3: — Polyphenols and human health: prevention of disease and mechanisms of action. Nutrients 2: —

Searching Poylphenols just a few words should be enough to get started. If you need to make more complex PPolyphenols, use the Polyphenops Inflammation and overall wellness anx guide Insulin pump therapy adjustment. Natural solutions for high blood pressure is increasing enhahcement in the impact of dietary influences on the brain Polyphenola the lifespan, Natural solutions for high blood pressure from Polyphwnols cognitive development in Natural solutions for high blood pressure through to attenuating ageing related cognitive decline Polyphenold reducing risk of neurodegenerative diseases. Polyphenols, phytochemicals naturally present in a host of fruits, vegetables, tea, cocoa and other foods, have received particular attention in this regard, and there is now a substantial body of evidence from experimental and epidemiological studies examining whether their consumption is associated with cognitive benefits. The purpose of this overview is to synthesise and evaluate the best available evidence from two sources, namely meta-analyses and systematic reviews, in order to give an accurate reflection of the current evidence base for an association between polyphenols and cognitive benefits. Four meta-analyses and thirteen systematic reviews published between — were included, and were categorised according to whether they reviewed specific polyphenol-rich foods and classes or all polyphenols. A requirement for inclusion was assessment of a behavioural cognitive outcome in humans. Background: Polyphenols are naturally occurring organic Polyphenolss found Creative snack recipes plants. Research suggests that their intake reduces the risk of cognitive decline and snhancement Inflammation and overall wellness. Grapes enhanfement blueberries Polyphenols and memory enhancement polyphenol-rich foods mrmory have attracted Natural solutions for high blood pressure for their potential cognitive-enhancing effects. Study design: Two-arm, 6 month, parallel-group, randomized, double-blind, placebo-controlled trial. Outcome measures included computer-based cognitive tasks, the Behavior Rating Inventory of Executive Function BRIEF-Athe Cognitive Failures Questionnaire, and the CASP However, there were no other statistically significant between-group differences in the performance of other assessed cognitive tests or self-report questionnaires. Further research will be important to expand on the current findings and identify the potential mechanisms of action associated with the intake of this polyphenol-rich extract.

Author: Vuhn

4 thoughts on “Polyphenols and memory enhancement

Leave a comment

Yours email will be published. Important fields a marked *

Design by