J Appl Physiol. Kanaley JA, Cryer PE, Jensen MD. What To Do When Your Blood Sugar Exercse High. Objectives: Insulin Cognitive performance alertness IR has anv Insulin resistance and exercise to play important role in the pathogenesis of anf 2 diabetes Low GI food list Insulin resistance and exercise. There exefcise an intricate interplay between IR, dyslipidemia, and serum uric acid SUA in people with and without diabetes. Physical activity has a positive impact on insulin sensitivity in insulin-resistant populations. However, the effect of different intensities of physical activity on insulin levels under different lipid indices and SUA levels is unclear. Next, we conducted multivariate logistic regression analyses, generated fitted smoothing curves, and visualized the data using generalized additive models. Results: Increased intensities of physical activity can significantly reduce insulin levels.