Nitric oxide and immune system support -
NO plays an essential role in the function of the immune response as defense against infectious organisms, an inducer or suppressor of apoptosis, or an immunoregulator. Inducible NOS iNOS or NOS2 production of Nitric Oxide is part of the immune response.
NO is toxic to viruses, bacteria, fungi, and other pathogens. NO regulates the functional activity, growth, and death of many immune and inflammatory cell types, including macrophages, T lymphocytes, antigen presenting cells, mast cells, neutrophils, and natural killer NK cells.
NO may inhibit an early stage in viral replication and prevent viral spread and promote viral clearance and recovery. Likewise, NO donors have been shown to inhibit viral replication.
Enhanced clotting and sluggish blood flow result in systemic hypoxia in oxygen-sensitive organs such as the kidneys. The lung is the beneficiary of the most blood flow of any organ of the body, so the potential for trouble to develop in the lung due to vascular insult is very high.
Vasculature depleted of NO suffers from persistent inflammation and blunted delivery of oxygen and removal of toxic byproducts through stagnant blood flow into and out of hypoxic tissue. According to Nathan S.
The primary textbook used in many medical schools is Robbins Pathology. This is basic physiology. The regulation of blood flow and circulation is based on your ability to produce Nitric Oxide. Cortisol inhibits iNOS affecting the immune response.
Stress also increases ROS in the mitochondria, from NADPH oxidase NOX and xanthine oxidase. This increased oxidative stress uncouples the NOS enzyme increasing superoxide production and oxidative stress. Additionally, cortisol decreases the membrane transport of l-arginine. NO down-regulates inflammatory cytokines and decreases mast cell degranulation and histamine release.
A good portion of our immune system is located in our intestinal tract. Therefore, supporting the health of our intestinal tract increases the health of our immune response.
As a result, these invaders are swiftly neutralised, ensuring that they don't get a foothold in our lungs or respiratory tracts. Chronic inflammation in our respiratory system can lead to a host of problems, from asthma to chronic obstructive pulmonary disease. Here again, NO comes to the rescue.
Its role in managing inflammation cannot be understated. By modulating the inflammatory response, NO ensures our air passages remain clear and healthy, facilitating easy breathing.
Beyond direct defence and inflammation management, NO offers a dual protective mechanism. On one hand, it confronts and neutralises potential respiratory threats directly.
On the other, by ensuring optimal health of our respiratory passages, it reduces the chances of chronic respiratory conditions from developing in the first place. Vitamin C and Vitamin E are well-known antioxidants. Their role in neutralising free radicals enhances the effects of NO.
While NO battles pathogens, these vitamins ensure that cells remain protected from oxidative stress, a key factor in ageing and several diseases.
Zinc plays a pivotal role in the immune system. Its interaction with NO is quite synergistic. While NO deals with pathogens, zinc ensures that the white blood cells function optimally. It's a tag-team where both compounds work hand in hand to provide a more robust immune response.
Then there's Selenium. A trace mineral that's essential for health. Its antioxidant properties complement those of NO. Understanding the right dose is crucial when considering nitric oxide supplementation.
It's always a good idea to start with the basics: consultation. A healthcare professional can provide guidance tailored to individual needs, ensuring that the NO supplement intake is not only effective but also safe.
The body's requirements vary. Factors like age, activity level, existing health conditions, and even genetics play a role. Recognising that a one-size-fits-all approach doesn't apply to NO supplements is essential. Customising intake based on these factors can lead to optimal results.
Beyond individual requirements, there's the matter of purity and quality. Not all supplements are created equal. Ensuring that the chosen NO supplement is of high quality, devoid of contaminants, and sourced responsibly can make all the difference in its effectiveness and safety.
While the benefits of NO are numerous, it's essential to be aware of potential side effects. Common side effects can include headaches, stomach upset, or even changes in blood pressure. Being attuned to one's body and recognising these early can ensure timely intervention.
It's worth noting that excessive NO can lead to over-dilation of blood vessels, which might result in low blood pressure. Always adhere to recommended doses and consult with a healthcare professional if any unusual symptoms arise. Balancing the intake with other dietary elements is also crucial.
A diet rich in antioxidants can help counter any potential oxidative stress from excessive NO. Once again, the mantra is moderation and awareness.
For more everything you need to know about nitric oxide and the role it plays in the human body, check out our comprehensive information page here. We've created a Nitric Oxide boosting supplement with a combination of ingredients required by our bodies to produce optimal amounts of nitric oxide.
Our supplement comes as an easy to mix, great tasting powder, offering a therapeutic dose in each scoop. Learn more about it here. Ron Goedeke MD, BSc Hons MBChB, FNZCAM. Ron Goedeke, an expert in the domain of functional medicine, dedicates his practice to uncovering the root causes of health issues by focusing on nutrition and supplement-based healing and health optimisation strategies.
An esteemed founding member of the New Zealand College of Appearance Medicine, Dr. Goedeke's professional journey has always been aligned with cutting-edge health concepts. Having been actively involved with the American Academy of Anti-Aging Medicine since , he brings over two decades of knowledge and experience in the field of anti-aging medicine, making him an eminent figure in this evolving realm of healthcare.
Throughout his career, Dr. Goedeke has been steadfast in his commitment to leverage appropriate nutritional guidance and supplementation to encourage optimal health. This has allowed him to ascend as one of the most trusted authorities in the arena of nutritional medicine in New Zealand.
His expertise in the intricate relationship between diet, nutritional supplements, and overall health forms the backbone of his treatment approach, allowing patients to benefit from a balanced and sustainable pathway to improved wellbeing. Just added to your cart. Continue Shopping.
Close search. Home Nitric Oxide Strengthening Your Immunity: How Nitric Oxide Supplements Can Help. Strengthening Your Immunity: How Nitric Oxide Supplements Can Help by Ron Goedeke.
The Immune System's Arsenal: Key Players and Their Functions Your immune system is your body's own superhero team, tirelessly defending against invaders. Nitric Oxide Decoded: Its Production, Release, and Biological Importance Nitric oxide NO , a simple molecule, has profound effects on health.
NO's Antibacterial Action: Combatting Pathogenic Invaders When it comes to fighting off bacterial threats, NO is a heavyweight champion. Optimising White Blood Cell Movement: NO's Role in Vasodilation and Immune Surveillance Ensuring rapid and efficient movement of our immune cells is pivotal, and NO is the key player here.
Exercise-Induced Immunity Boost: The Central Role of Nitric Oxide Embracing physical activity offers more benefits than just fitness, thanks to NO. Defending the Airways: How NO Shields the Respiratory System from Pathogens NO is crucial for maintaining the health of our respiratory system.
Diet and Nitric Oxide: Foods That Naturally Increase NO Levels What we eat can have a profound effect on our NO levels, and by extension, our overall health. Among the dietary champions boosting NO are leafy greens. Spinach, kale, and arugula, to name a few, are packed with nitrates. When we consume these veggies, our body converts these nitrates to nitrites and eventually to nitric oxide.
Incorporating these into our diet can be a natural way to bolster our NO levels and, consequently, our health. Beetroot has gained popularity in recent years as a superfood, and for a good reason. It's a potent source of nitrates. Whether consumed as juice, salad, or in roasted form, beetroot offers a delicious path to increased NO production.
The list doesn't end with veggies. Nuts, seeds, and fruits play their part too. Walnuts, pomegranates, and berries, for instance, ensure our body has the necessary precursors for producing NO.
And for those with a sweet tooth, there's more good news. Dark chocolate, rich in flavanols, not only delights the palate but also promotes NO production. Determining the Right Dose: Scientific Insights on NO Supplement Intake Understanding the right dose is crucial when considering nitric oxide supplementation.
Safety First: Recognising and Managing Side Effects of NO Supplements While the benefits of NO are numerous, it's essential to be aware of potential side effects.
Summary The Immune System's Arsenal: Key Players and Their Functions White blood cells, particularly phagocytes and lymphocytes, are the frontline defenders in the immune system, constantly vigilant against threats.
Nitric oxide is the critical syetem of your BMR and weight management tips that immkne is talking Mental clarity techniques. In Nitric oxide and immune system support post amd cover:. Many, if not most people have low levels of nitric oxide. Are you one of them? The research that supports the hypothetical link between low nitric oxide and risk for infection and risk for severe covid outcomes. The research showing that supplementing with nitrates can lower how bad an infection might get. Role in Biology. Role in Medicine. Production in cells. Regulation Nitruc NO production. Protein Nitrosylation.
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