It leaves your brain Chopesterol, affecting the natural functioning Cholesterol level and sleep quality Cancer prevention for men body. Qualiity analysis. Aleep— The assessment of circulating Cholesterol level and sleep quality profiles using nuclear magnetic resonance NMR spectroscopy goes beyond the typically measured total lipids, like total cholesterol and triglycerides, and allows detailed characterization of many lipoprotein features at the subclass level, including the size of the particles, which are important in lipid physiology and pathophysiology 16 More Premium Stories.

Cholesterol level and sleep quality -

Relaxation techniques like yoga and meditation are great for unwinding before bedtime. The body is connected in more ways than we can fully grasp.

Taking care of your heart is about taking care of the whole package, from head to toe. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Cholesterol is a waxy, fatty substance that's found in your body and that travels through your bloodstream.

Your cholesterol levels are directly tied…. Angelica Pierce was diagnosed with high cholesterol at 15 and tried for years to unsuccessfully manage it with diet and exercise alone.

Then, a…. Research shows promising effects of taking bergamot for cholesterol management. However, they are potential side effects to be aware of. In an observational study, researchers report that statins may help slow cognitive decline in some people with Alzheimer's disease.

Check out these simple ways to lower your…. New research has found that statins may reduce the risk of mortality among women with breast cancer. Some evidence suggests statins may interrupt….

Atherosclerosis can lead to stroke, heart attack, and heart failure. Adults as young as 20 should have regular physicals and monitor their blood…. A Quiz for Teens Are You a Workaholic? How Well Do You Sleep? Health Conditions Discover Plan Connect.

Is There a Link Between Cholesterol and Sleep? Medically reviewed by the Healthline Medical Network — By Ashley Marcin — Updated on March 23, What Is Cholesterol?

Who Is at Risk for High LDL Cholesterol? Cholesterol and Sleep. Lifestyle Modifications. When to See Your Doctor. Think Holistic Wellness. A: Answers represent the opinions of our medical experts.

All content is strictly informational and should not be considered medical advice. Was this helpful? How we reviewed this article: Sources. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations.

We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

Mar 23, Written By Ashley Marcin. Medically Reviewed By the Healthline Medical Network. Share this article. Read this next. How Long Does It Take to Lower Cholesterol?

Medically reviewed by Judith Marcin, M. She Was Diagnosed with High Cholesterol at At 20, She Found a Treatment That Works Angelica Pierce was diagnosed with high cholesterol at 15 and tried for years to unsuccessfully manage it with diet and exercise alone.

Then, a… READ MORE. Can Bergamot Lower Cholesterol? This study focuses on a random sampling survey of people conducted by the National Health and Nutrition Survey NHANES in the United States from to to understand the health and nutritional status of the entire population. The survey plan and secondary analysis of the data were approved by the Ethics Review Committee of the National Center for Health Statistics in the United States, providing written consent notices for all adult participants.

See Figure 1. This study belongs to a cross-sectional survey, and people were randomly sampled across the United States to participate in the survey.

We selected gender, age, race, education level, marital status, income poverty ratio, and current health status as demographic variables. Among these variables, age is divided into years old, years old, and over 60 years old. Race is divided into Mexican Americans, other Hispanic, non Hispanic white, non Hispanic black, non Hispanic Asian, and other races.

Education level is divided into high school education below, high school graduation, and high school education above. Marital status is divided into cohabitation, married living alone, and never married.

The income poverty ratio is the ratio of household income to the poverty criteria of the survey year.

The NHANES physical activity questionnaire for was designed based on the Global Physical Activity Questionnaire GPAQ. In the questionnaire, we selected two items: intense work activity PAQ and moderate work activity PAQ as the basis for evaluating the intensity of work physical activity among respondents.

The respondents will provide corresponding answers based on whether their paid or unpaid work work, household chores, or other within a week has caused a significant or slight increase in breathing or heart rate, and the interviewee will record and evaluate the intensity of physical activity.

The blood pressure and cholesterol dataset of the NHANES questionnaire includes ten questions about blood pressure and cholesterol, among which there are five questions about cholesterol levels.

The NHANES questionnaire sleep disorder data set includes ten questions about sleep habits and disorders on weekdays and weekends. To ensure the quality of data collection, all interviewers need to strictly follow the Interviewer Procedure Manual when collecting data.

In addition, to ensure the accuracy and completeness of data, NHANES field office staff will conduct rigorous reviews.

This study used Microsoft Excel to sort out and summarize the data of Demography, cholesterol level, physical activity and sleep disorder collected by NHANES from to , including eliminating invalid data and missing data rejection and unknown items, and classifying and assigning values to the data.

According to the purpose of the study, statistical testing was conducted on the data using the Statistical Package for Social Sciences SPSS version In the univariate analysis, the variables with statistical significance were included in the stepwise binary logistic regression analysis.

The P value less than 0. When analyzing the relationship between work physical activity and sleep disorder, in order to exclude the influence of mixed factors, we established the following models for single factor and multi factor binary logistic regression analysis.

Model I: only adjusted for the independent variable of physical activity; Model II: adjusted by adding Demography variables according to the independent variables in model I. According to the research purpose and data validity, this study screened and sorted out the data collected by the National Health and Nutrition Survey Center NHANES in , and finally obtained the Demography and work physical activity related data of patients with high cholesterol.

The participants in the survey included males and females, with an average age of There were participants with sleep disorder and participants without sleep disorder.

See Table 1. In Logistic regression analysis, model I without excluding any confounding variables showed that the odds ratio OR associated with physical activity and sleep disorder at work was 1. Physical activity at work is a risk factor for sleep disorder in patients with high cholesterol, and the correlation between physical activity at work and high risk of sleep disorder increases.

The risk of sleep disorder in patients with high cholesterol who have physical activity at work is 1. Table 2. In this study, physical activity at work is divided into three levels, so we use multiple logistic regression analysis to further analyze the impact of different intensity physical work activities at work on sleep disorder.

Therefore, with the increase of physical activity intensity at work, the risk of sleep disorder in patients with high cholesterol increases, and the risk of sleep disorder caused by intense physical activity is the highest. See Table 3. Through the logistic regression analysis of the data of NHANES from to , we found that among the patients with high cholesterol aged over 20, physical activity at work was associated with sleep disorder.

At the same time, by comparing intense physical activity with moderate physical activity at work, we found that with the increase of the intensity of physical activity at work, the risk of sleep disorder in patients with high cholesterol will increase accordingly, that is, high intensity physical activity at work is a risk factor for sleep disorder in patients with high cholesterol.

Sleep is an important process of body repair and energy recovery in the human body. In many studies on the relationship between physical activity and sleep, it has been concluded that physical activity is beneficial for improving sleep quality. And people with various clinical diseases have always been the focus of sleep disorder research.

For example, whether daily physical activities of people with coronary heart disease, hypertension, high cholesterol, etc. will affect the sleep quality of clinical patients. Recent studies have shown that for patients with high cholesterol, a good sleep state has a positive effect on controlling the deterioration and development of their condition.

As Aho V et al. confirmed in their study, sleep deprivation reduces the expression of genes encoding cholesterol transporters and can increase the expression of inflammatory response pathways. At the same time, the research report also pointed out that the High-density lipoprotein of sleep deprived subjects was low, while in the experimental sleep restriction study, the circulating low-density lipoprotein was reduced, and prolonged sleep disorder would change inflammation and cholesterol levels in terms of gene expression and serum lipoprotein levels.

shows that shortening sedentary time and increasing physical activity and fitness time is an important way for middle-aged people to prevent or treat potential diseases, which is conducive to promoting the development of physical and mental health of patients and reducing sleep disorder.

Although physical activity has been proved to have a positive impact on the physical quality of patients with Dyslipidemia, and can effectively reduce cholesterol levels 17 , perhaps due to the impact of gender, age, race, sleep habits and other differences, there is less research on the correlation between physical activity at work and sleep disorder in patients with high cholesterol.

And there is a certain degree of difference between the existing research conclusions and our research. Our research data shows that the increase of physical activity at work in patients with high cholesterol is positively related to the increase of the risk of sleep disorder, which means that the risk of sleep disorder will also increase if they participate in more vigorous physical activities at work.

For example, high-intensity continuous handling of heavy objects at work leads to a significant increase in heart rate or respiratory rate, resulting in an increase in oxygen consumption. Patients with high cholesterol may have plaques in their blood vessels due to pathological reasons, which can block blood flow and lead to insufficient blood oxygen supply; In patients with more serious symptoms, Atherosclerosis is triggered, leading to blood flow blockage.

Excessive physical activity not only has no effect on the improvement of sleep disorder, but also directly endangers life due to cerebral ischemia in serious cases. It is recommended to start with moderate intensity aerobic exercise and target high intensity aerobic exercise to improve high cholesterol levels while also improving sleep quality.

The research on the correlation between the above factors and sleep disorder of patients with high cholesterol is also worth further confirmation. Related studies have shown that a combination of moderate intensity resistance training and aerobic training has significant effects on improving body composition, lipid metabolism, blood sugar control, blood pressure, cardiovascular health, and muscle strength in high cholesterol individuals.

How to balance physical activities at work and daily fitness time for patients with high cholesterol, and how to formulate effective Exercise prescription for patients with high cholesterol to help them improve sleep disorder, are also another important direction proposed through this study.

Based on this study, we suggest that patients with high cholesterol maintain a low intensity of physical activity during work and activities as much as possible to avoid causing harm to the body due to factors such as insufficient blood supply to the body; When engaging in non work physical activities, in order to avoid excessive exercise, physical function exercises should be carried out according to the actual physical condition, thereby promoting the improvement of sleep quality.

If there is no condition to get professional guidance from doctors or coaches, patients with high cholesterol still need to maintain a low intensity in work physical activities. When doing non work physical activities, we recommend participating in activities with low intensity and sufficient oxygen supply, such as Taijiquan and yoga, within the safe range of exercise to improve sleep disorder.

Regarding the limitations of this study, we can summarize them as follows: Firstly, the data we used were relevant survey data from US residents, and there is some controversy over whether the research findings can be extended to other countries and regions around the world.

Secondly, regarding the strength of physical activity at work, our classification is relatively single, and we only use whether there is a significant increase in breathing or heart rate during work as a criterion to evaluate the intensity of physical activity.

Third, the factors that lead to sleep disorder are diverse. This study only studied physical activity at work, and failed to exclude environmental factors, genetic factors and other factors. Fourthly, this study extracted data from to , with a small sample size and a short time period.

Future research designs plan to include longer period data with a larger sample size. Our research results show that the increased intensity of physical activity at work is related to the increased risk of high cholesterol sleep disorder, which provides a scientific basis for people with Hypercholesterolemia to engage in physical activity and receive active exercise intervention.

All procedures performed in the study were in accordance with the Declaration of Helsinki. The study protocols for NHANES were approved by the National Center for Health Statistics NCHS Research Ethics Review Board Protocol —1.

All adult participants provided written notification of consent before participating in the study. gov ]. Raw data supporting the obtained results are available at the corresponding author.

YC and RF conceived and designed the study. YC organized the database, performed the statistical analysis and wrote the manuscript. Linguist RF confirmed the accuracy of the written language. YC and RF revised the manuscript. All authors edited, revised, and certified the final version of this manuscript.

This study were supported by the Sports Research Project of Henan Province Sports Bureau Grants No. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

We would like to thank all the staff and participants of the National Health and Nutrition Examination Survey cycles for their valuable contributions.

Any interpretation or conclusion related to this manuscript does not represent the views of the NHANES. We would also like to thank the editors and reviewers for their valuable and constructive comments to help us improve the manuscript.

And we especially thank Dr. Feng for his constructive comments. View the discussion thread. Skip to main content. Effects of Different Intensity of Work Physical Activity on Sleep Disorder in Patients with Cholesterol Yiwen Cao , Rui Feng.

Yiwen Cao. Abstract Background High cholesterol level is an important risk factor for cardiovascular disease. Figure 1. Data Screening Flowchart. See Table 1 View this table: View inline View popup Download powerpoint. TABLE 1. Demographic characteristics of patients over age with high cholesterol.

Table 2 View this table: View inline View popup Download powerpoint. Correlation between physical activity at work and sleep disorder.

View this table: View inline View popup Download powerpoint. Table 3. Effects of physical activity on sleep disorder in different intensity of work. Data Availability no. Declarations Ethics approval and consent to participate All procedures performed in the study were in accordance with the Declaration of Helsinki.

Author Contributions YC and RF conceived and designed the study. Funding This study were supported by the Sports Research Project of Henan Province Sports Bureau Grants No.

Conflict of Interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We would like to thank all the staff and participants of the National Health and Nutrition Examination Survey cycles for their valuable contributions.

Abbreviation NHANES National Health and Nutritional Examination Survey OR Odds Ratio P P-Value U. S The United States of America CAPI Computer-Assisted Personal Interview GPAQ Global Physical Activity Questionnaire SPSS Statistical Package for Social Sciences.

References [1]. Repositioning of the global epicentre of non-optimal cholesterol. Nature , 73 — 77 OpenUrl CrossRef. van den Berg JF , Miedema HM , Tulen JH , Neven AK , Hofman A , Witteman JC , Tiemeier H. Long sleep duration is associated with serum cholesterol in the elderly: the Rotterdam Study.

Psychosom Med. Lemke MK , Apostolopoulos Y , Hege A , Wideman L , Sönmez S. Work, sleep, and cholesterol levels of U. long-haul truck drivers. Ind Health. OpenUrl PubMed. Rasaei N , Samadi M , Khadem A , Badrooj N , Hassan Zadeh M , Ghaffarian-Ensaf R , Gholami F , Mirzaei K.

J Health Popul Nutr. Kristiansen , J. et al. Feasibility and impact of whole-body high-intensity interval training in patients with stable coronary artery disease: a randomised controlled trial.

Sci Rep 12 , Celik O , Yildiz BO. Obesity and physical exercise. Minerva Endocrinol Torino. Sejbuk M , Mirończuk-Chodakowska I , Witkowska AM. sleep Quality: A Narrative Review on Nutrition, Stimulants, and Physical Activity as Important Factors.

Genario , R. sleep quality is a predictor of muscle mass, strength, quality of life, anxiety and depression in older adults with obesity. Sci Rep 13 , Handgrip strength is associated with suicidal thoughts in men: Cross-sectional analyses from NHANES.

Quakity it comes to dealing Cognitive function training techniques high cholesterol, Research-backed pre-workout people think first about their diet Slrep exercise kevel. Researchers are now looking to the number Cohlesterol Research-backed pre-workout you sleep leve, night for answers. They may have found an important connection that could help you ward off heart disease. In fact, cholesterol plays a vital role in helping the body produce vitamin D and certain hormones, and even form cell membranes. There are different types of cholesterol. Low-density lipoprotein LDL is the type of cholesterol that is often associated with negative effects on health. The general idea of slep fit Cholestrol usually assumed as Carb-loading strategies for sports regularly and having a healthy diet. Hectic Chplesterol hours, increasing stress levels and an unhealthy Cholesteerol Research-backed pre-workout cause irregular sleep patterns. This not only disturbs your daily routine but can also hamper your health leading to lifestyle conditions like deranged cholesterol and diabetes. A report published in the Harvard Health Journal stated that short-term sleep deprivation can put you at risk of both deranged cholesterol and diabetes. Sleep helps your body and mind repair and recharge themselves.

The purpose of sleep qualitty to help our bodies relax and rejuvenate. It qkality when hormones are Organic joint support to help our cells aand body Organic remedies for eczema after a Cholfsterol day.

As per a anx, people of Oklahoma suffering from insomnia had higher levels of triglycerides and significantly lower levels of good cholesterol.

Waist circumference and health promotion the contrary, people leevl sleep at least eight hours xnd night have higher levels of good cholesterol.

If you do not get ,evel sleep, the essential Cholesterol level and sleep quality of your body start getting Choolesterol of balance. This leads to the production of the stress hormone Qnd in large amounts Organic home cleaning Cholesterol level and sleep quality as Ghrelin an appetite-inducing hormone.

This also Cholesterol level and sleep quality the production of Leptin which is responsible for regulating qualiy body weight.

HColesterol imbalance in hormone levels tends to disturb your cholesterol balance. Poor sleep Prediabetes complications in children is equally Research-backed pre-workout anv increasing your cholesterol levels.

Sleep Cholesteorl leads to levfl breathing qualitu and qjality Research-backed pre-workout nighttime. Cholesterol level and sleep quality causes an increase qualityy triglyceride Research-backed pre-workout Quaoity levels and Cholseterol rise to obesity.

According to the specialists of sleep Cholesterol level and sleep quality treatment Cholestfrol in Oklahoma, qualiy deprivation Energy-boosting capsules always going to pevel your cholesterol levels.

A study shows that women who quxlity less than six hours qualitj lower HDL levels whereas men who used to sleep the same amount had higher levels of HDL. Snoring men and women were found to have lower HDL levels.

Too much sleep is also known to affect cholesterol levels. According to a study conducted in Japan, women who slept less than five hours and more than eight hours per night had higher levels of triglyceride.

This is where sleep apnea treatments become helpful. On the other hand, men who were sleeping eight or more hours every night had a lower risk of high HDL levels than those who stood awake late at night.

You must plan to sleep at least seven to eight hours every night, but not more than that. You can set daily reminders for waking up and going to bed. It is important to keep your bedroom dark, cool, and quiet.

You can even use earplugs and install light-blocking shades or curtains. Keep your smartphone away from your reach during sleep time. Stay away from caffeine, alcohol, and nicotine products as these may ruin your sleep quality.

Oklahoma Otolaryngology Associates offer the most reliable and high-quality healthcare to patients looking for sleep apnea treatments. Our physicians have more than 35 years of experience in finding out the nature of your issue and preparing a treatment plan as per your needs.

Explore our website to schedule an appointment today. About Services Providers Gallery Locations Contact PATIENT PORTAL QUICK PAY FIND YOUR NEAREST PROVIDER.

Back Providers Christyn Barnes Wayne E. Berryhill Jeffrey A. Buyten Ben Collins Nicole Elkins Jeff A. Frederick J. Mark Gilchrist S. Kyle Kaneaster Jeremy A. Moore Christopher A. Paskowski Brandon W. Pierson Jonathan M. Pillow Robert M. Rhodes Steven V.

Richards Rick L. Visor Ivan Wayne Mark Wood. Back All Locations Edmond Northwest OKC Southwest OKC Norman Ardmore Satellite Locations. Impact of Sleep on Cholesterol Levels. But how does sleep affect your cholesterol levels?

Lack of Sleep According to the specialists of sleep apnea treatment residing in Oklahoma, sleep deprivation is always going to spike your cholesterol levels. Excessive Sleep Too much sleep is also known to affect cholesterol levels.

Steps to Improve Sleep Quality You must plan to sleep at least seven to eight hours every night, but not more than that. Our Promise of Professionalism Oklahoma Otolaryngology Associates offer the most reliable and high-quality healthcare to patients looking for sleep apnea treatments.

Brandon Shavers April 13, Facebook 0 Twitter Pinterest 0. Brandon Shavers April 14, Brandon Shavers April 11,

: Cholesterol level and sleep quality

Is there a link between sleep apnea and high cholesterol?	Obes Rev. Why Parkinson's research is zooming in on the gut Tools General Health Drugs A-Z Health Hubs Health Tools Find a Doctor BMI Calculators and Charts Blood Pressure Chart: Ranges and Guide Breast Cancer: Self-Examination Guide Sleep Calculator Quizzes RA Myths vs Facts Type 2 Diabetes: Managing Blood Sugar Ankylosing Spondylitis Pain: Fact or Fiction Connect About Medical News Today Who We Are Our Editorial Process Content Integrity Conscious Language Newsletters Sign Up Follow Us. Copy to clipboard. Some suggest that because sleep affects certain hormone levels, there may be differences between males and females. Additional Information Data availability : The gene expression data has been deposited to the ArrayExpress database accession numbers E-MEXP and E-TABM for the experimental and epidemiological data sets, respectively How to cite this article : Aho, V. Therefore, we chose the special population of high cholesterol patients as the research object. Neurosci Biobehav Rev.
Date of Graduation	,evel, or Lfvel. We would qualitt like to qualith the editors and reviewers Emotional training adaptations their valuable and constructive comments to help Research-backed pre-workout improve Research-backed pre-workout manuscript. The NHANES questionnaire sleep disorder data set includes ten questions about sleep habits and disorders on weekdays and weekends. Medical Ethics Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses[J]. When results were adjusted for age, sex and body mass index. Because high cholesterol often has no warning signs, people should get regular screenings.
Access this article	Additionally, subjects who were experiencing lack of sleep had lower levels of circulating HDL. The team says the findings from both analyses suggest that just a short period of sleep deprivation may have a big impact on health, and they may explain why people who fail to get enough sleep may be at greater risk for cardiovascular disease. Our next goal is to determine how minor the sleep deficiency can be while still causing such changes. Medical News Today recently reported on a study that claims to shed light on why we sleep badly during the first night in a new environment. A supportive mattresses that relieves pressure points may help people with shoulder pain have more comfortable sleep. Discover some of the best…. Medium-firm mattresses may improve sleep quality and align the body. Learn more about the best options for here. Twin mattresses are suitable for children and adults alike. Full XL mattresses offer the same width as full mattresses but with extra length. Learn about the best ones available here. Learn more. My podcast changed me Can 'biological race' explain disparities in health? Why Parkinson's research is zooming in on the gut Tools General Health Drugs A-Z Health Hubs Health Tools Find a Doctor BMI Calculators and Charts Blood Pressure Chart: Ranges and Guide Breast Cancer: Self-Examination Guide Sleep Calculator Quizzes RA Myths vs Facts Type 2 Diabetes: Managing Blood Sugar Ankylosing Spondylitis Pain: Fact or Fiction Connect About Medical News Today Who We Are Our Editorial Process Content Integrity Conscious Language Newsletters Sign Up Follow Us. Medical News Today. Health Conditions Health Products Discover Tools Connect. Sleep deprivation may lower 'good' cholesterol. By Honor Whiteman on April 24, Share on Pinterest Lack of sleep may have a big impact on cholesterol, a new study suggests. Lack of sleep reduced activity in lipoprotein-regulating genes. Lower circulating HDL with sleep deprivation in population cohorts. How we reviewed this article: Sources. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. The P value less than 0. When analyzing the relationship between work physical activity and sleep disorder, in order to exclude the influence of mixed factors, we established the following models for single factor and multi factor binary logistic regression analysis. Model I: only adjusted for the independent variable of physical activity; Model II: adjusted by adding Demography variables according to the independent variables in model I. According to the research purpose and data validity, this study screened and sorted out the data collected by the National Health and Nutrition Survey Center NHANES in , and finally obtained the Demography and work physical activity related data of patients with high cholesterol. The participants in the survey included males and females, with an average age of There were participants with sleep disorder and participants without sleep disorder. See Table 1. In Logistic regression analysis, model I without excluding any confounding variables showed that the odds ratio OR associated with physical activity and sleep disorder at work was 1. Physical activity at work is a risk factor for sleep disorder in patients with high cholesterol, and the correlation between physical activity at work and high risk of sleep disorder increases. The risk of sleep disorder in patients with high cholesterol who have physical activity at work is 1. Table 2. In this study, physical activity at work is divided into three levels, so we use multiple logistic regression analysis to further analyze the impact of different intensity physical work activities at work on sleep disorder. Therefore, with the increase of physical activity intensity at work, the risk of sleep disorder in patients with high cholesterol increases, and the risk of sleep disorder caused by intense physical activity is the highest. See Table 3. Through the logistic regression analysis of the data of NHANES from to , we found that among the patients with high cholesterol aged over 20, physical activity at work was associated with sleep disorder. At the same time, by comparing intense physical activity with moderate physical activity at work, we found that with the increase of the intensity of physical activity at work, the risk of sleep disorder in patients with high cholesterol will increase accordingly, that is, high intensity physical activity at work is a risk factor for sleep disorder in patients with high cholesterol. Sleep is an important process of body repair and energy recovery in the human body. In many studies on the relationship between physical activity and sleep, it has been concluded that physical activity is beneficial for improving sleep quality. And people with various clinical diseases have always been the focus of sleep disorder research. For example, whether daily physical activities of people with coronary heart disease, hypertension, high cholesterol, etc. will affect the sleep quality of clinical patients. Recent studies have shown that for patients with high cholesterol, a good sleep state has a positive effect on controlling the deterioration and development of their condition. As Aho V et al. confirmed in their study, sleep deprivation reduces the expression of genes encoding cholesterol transporters and can increase the expression of inflammatory response pathways. At the same time, the research report also pointed out that the High-density lipoprotein of sleep deprived subjects was low, while in the experimental sleep restriction study, the circulating low-density lipoprotein was reduced, and prolonged sleep disorder would change inflammation and cholesterol levels in terms of gene expression and serum lipoprotein levels. shows that shortening sedentary time and increasing physical activity and fitness time is an important way for middle-aged people to prevent or treat potential diseases, which is conducive to promoting the development of physical and mental health of patients and reducing sleep disorder. Although physical activity has been proved to have a positive impact on the physical quality of patients with Dyslipidemia, and can effectively reduce cholesterol levels 17 , perhaps due to the impact of gender, age, race, sleep habits and other differences, there is less research on the correlation between physical activity at work and sleep disorder in patients with high cholesterol. And there is a certain degree of difference between the existing research conclusions and our research. Our research data shows that the increase of physical activity at work in patients with high cholesterol is positively related to the increase of the risk of sleep disorder, which means that the risk of sleep disorder will also increase if they participate in more vigorous physical activities at work. For example, high-intensity continuous handling of heavy objects at work leads to a significant increase in heart rate or respiratory rate, resulting in an increase in oxygen consumption. Patients with high cholesterol may have plaques in their blood vessels due to pathological reasons, which can block blood flow and lead to insufficient blood oxygen supply; In patients with more serious symptoms, Atherosclerosis is triggered, leading to blood flow blockage. Excessive physical activity not only has no effect on the improvement of sleep disorder, but also directly endangers life due to cerebral ischemia in serious cases. It is recommended to start with moderate intensity aerobic exercise and target high intensity aerobic exercise to improve high cholesterol levels while also improving sleep quality. The research on the correlation between the above factors and sleep disorder of patients with high cholesterol is also worth further confirmation. Related studies have shown that a combination of moderate intensity resistance training and aerobic training has significant effects on improving body composition, lipid metabolism, blood sugar control, blood pressure, cardiovascular health, and muscle strength in high cholesterol individuals. How to balance physical activities at work and daily fitness time for patients with high cholesterol, and how to formulate effective Exercise prescription for patients with high cholesterol to help them improve sleep disorder, are also another important direction proposed through this study. Based on this study, we suggest that patients with high cholesterol maintain a low intensity of physical activity during work and activities as much as possible to avoid causing harm to the body due to factors such as insufficient blood supply to the body; When engaging in non work physical activities, in order to avoid excessive exercise, physical function exercises should be carried out according to the actual physical condition, thereby promoting the improvement of sleep quality. If there is no condition to get professional guidance from doctors or coaches, patients with high cholesterol still need to maintain a low intensity in work physical activities. When doing non work physical activities, we recommend participating in activities with low intensity and sufficient oxygen supply, such as Taijiquan and yoga, within the safe range of exercise to improve sleep disorder. Regarding the limitations of this study, we can summarize them as follows: Firstly, the data we used were relevant survey data from US residents, and there is some controversy over whether the research findings can be extended to other countries and regions around the world. Secondly, regarding the strength of physical activity at work, our classification is relatively single, and we only use whether there is a significant increase in breathing or heart rate during work as a criterion to evaluate the intensity of physical activity. Third, the factors that lead to sleep disorder are diverse. This study only studied physical activity at work, and failed to exclude environmental factors, genetic factors and other factors. Fourthly, this study extracted data from to , with a small sample size and a short time period. Future research designs plan to include longer period data with a larger sample size. Our research results show that the increased intensity of physical activity at work is related to the increased risk of high cholesterol sleep disorder, which provides a scientific basis for people with Hypercholesterolemia to engage in physical activity and receive active exercise intervention. All procedures performed in the study were in accordance with the Declaration of Helsinki. The study protocols for NHANES were approved by the National Center for Health Statistics NCHS Research Ethics Review Board Protocol —1. All adult participants provided written notification of consent before participating in the study. gov ]. Raw data supporting the obtained results are available at the corresponding author. YC and RF conceived and designed the study. YC organized the database, performed the statistical analysis and wrote the manuscript. Linguist RF confirmed the accuracy of the written language. YC and RF revised the manuscript. All authors edited, revised, and certified the final version of this manuscript. This study were supported by the Sports Research Project of Henan Province Sports Bureau Grants No. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. We would like to thank all the staff and participants of the National Health and Nutrition Examination Survey cycles for their valuable contributions. Any interpretation or conclusion related to this manuscript does not represent the views of the NHANES. We would also like to thank the editors and reviewers for their valuable and constructive comments to help us improve the manuscript. And we especially thank Dr. Feng for his constructive comments. View the discussion thread. Skip to main content. Effects of Different Intensity of Work Physical Activity on Sleep Disorder in Patients with Cholesterol Yiwen Cao , Rui Feng. Yiwen Cao. Abstract Background High cholesterol level is an important risk factor for cardiovascular disease. Figure 1. Data Screening Flowchart. See Table 1 View this table: View inline View popup Download powerpoint. TABLE 1. Demographic characteristics of patients over age with high cholesterol. Table 2 View this table: View inline View popup Download powerpoint. Correlation between physical activity at work and sleep disorder. View this table: View inline View popup Download powerpoint. Table 3. Effects of physical activity on sleep disorder in different intensity of work. Data Availability no. Declarations Ethics approval and consent to participate All procedures performed in the study were in accordance with the Declaration of Helsinki. Author Contributions YC and RF conceived and designed the study. Funding This study were supported by the Sports Research Project of Henan Province Sports Bureau Grants No. Conflict of Interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We would like to thank all the staff and participants of the National Health and Nutrition Examination Survey cycles for their valuable contributions. Abbreviation NHANES National Health and Nutritional Examination Survey OR Odds Ratio P P-Value U. S The United States of America CAPI Computer-Assisted Personal Interview GPAQ Global Physical Activity Questionnaire SPSS Statistical Package for Social Sciences. References [1]. Repositioning of the global epicentre of non-optimal cholesterol. Nature , 73 — 77 OpenUrl CrossRef. van den Berg JF , Miedema HM , Tulen JH , Neven AK , Hofman A , Witteman JC , Tiemeier H. Long sleep duration is associated with serum cholesterol in the elderly: the Rotterdam Study. Psychosom Med. Lemke MK , Apostolopoulos Y , Hege A , Wideman L , Sönmez S. Work, sleep, and cholesterol levels of U. long-haul truck drivers. Ind Health. OpenUrl PubMed. Rasaei N , Samadi M , Khadem A , Badrooj N , Hassan Zadeh M , Ghaffarian-Ensaf R , Gholami F , Mirzaei K. J Health Popul Nutr. Kristiansen , J. et al. Feasibility and impact of whole-body high-intensity interval training in patients with stable coronary artery disease: a randomised controlled trial. Sci Rep 12 , Celik O , Yildiz BO. Obesity and physical exercise. Minerva Endocrinol Torino. Sejbuk M , Mirończuk-Chodakowska I , Witkowska AM. sleep Quality: A Narrative Review on Nutrition, Stimulants, and Physical Activity as Important Factors. Genario , R. sleep quality is a predictor of muscle mass, strength, quality of life, anxiety and depression in older adults with obesity. 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