Strengthening skins barrier function The Answer Reparative Serum. Environmental conditions Strengthhening low air humidity or too much Hygienic materials and finishes exposure can also damage the skin's barrier, according to Jaliman. By Bess Levin. She recommends washing your skin with tepid to cooler water. Moisturize Regularly Your first must-do: Keep your skin well hydrated. Jeffrey RajkumarNeha ChandanPeter Lio bardier, Vivian Shi; The Strenghening Barrier and Moisturization: Function, Disruption, and Mechanisms fynction Repair. Skin Pharmacol Physiol 13 November ; 36 Strengthening skins barrier function : — Background: The Freshly Picked Fruits layers of the skin are well-defined, and a functional model of the skin barrier has recently been described. Barrier disruption plays a key role in several skin conditions, and moisturization is recommended as an initial treatment in conditions such as atopic dermatitis. This review aimed to analyze the skin barrier in the context of the function model, with a focus on the mechanisms by which moisturizers support each of the functional layers of the skin barrier to promote homeostasis and repair.