Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle Holloway, Graham P. Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle.

Cell Reports. Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men Holwerda, Andrew M. Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men.

Temporal response of angiogenesis and hypertrophy to resistance training in young men Holloway, Tanya M. Temporal response of angiogenesis and hypertrophy to resistance training in young men.

Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates Langer, Henning, Senden, Joan M.

Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates. Frontiers in Physiology. Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[c]-leucine PET Smeets, Joey S.

J and Van Loon, Luc. Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[c]-leucine PET. Brain: a journal of neurology. Skeletal muscle fiber characteristics in patients with chronic heart failure: Impact of disease severity and relation with muscle oxygenation during exercise Niemeijer, Victor M.

Skeletal muscle fiber characteristics in patients with chronic heart failure: Impact of disease severity and relation with muscle oxygenation during exercise. Dose-response effects of supplementation with calcifediol on serum hydroxyvitamin D status and its metabolites: a randomized controlled trial in older adults Vaes, Anouk M.

Dose-response effects of supplementation with calcifediol on serum hydroxyvitamin D status and its metabolites: a randomized controlled trial in older adults. Clinical Nutrition. Increasing vegetable intake to obtain the health promoting and ergogenic effects of dietary nitrate Van der Avoort, Cindy M.

Increasing vegetable intake to obtain the health promoting and ergogenic effects of dietary nitrate. European Journal of Clinical Nutrition.

Effects of creatine and carbohydrate loading on cycling time trial performance Tomcik, Kristyen A. Effects of creatine and carbohydrate loading on cycling time trial performance.

IOC consensus statement: dietary supplements and the high-performance athlete Maughan, Ronald J. Engebretsen, Lars. IOC consensus statement: dietary supplements and the high-performance athlete British Journal of Sports Medicine.

The dutch physical activity guidelines Weggemans, Rianne M. The dutch physical activity guidelines. International Journal of Behavioral Nutrition and Physical Activity. Interventional strategies to combat muscle disuse atrophy in humans: Focus on neuromuscular electrical stimulation and dietary protein Dirks, Marlou L.

and van Loon, Luc. Interventional strategies to combat muscle disuse atrophy in humans: Focus on neuromuscular electrical stimulation and dietary protein.

IOC Consensus Statement: Dietary Supplements and the High-Performance Athlete Maughan, Ronald J. IOC Consensus Statement: Dietary Supplements and the High-Performance Athlete. A novel in vitro model for the assessment of postnatal myonuclear accretion Kneppers, Anita, Verdijk, Lex B.

A novel in vitro model for the assessment of postnatal myonuclear accretion. Skeletal Muscle. Protein supplementation after exercise and before sleep does not further augment muscle mass and strength gains during resistance exercise training in active older men Holwerda, Andrew M.

Protein supplementation after exercise and before sleep does not further augment muscle mass and strength gains during resistance exercise training in active older men. Protein content and amino acid composition of commercially available plant-based protein isolates Gorissen, Stefan H.

Protein content and amino acid composition of commercially available plant-based protein isolates. Amino Acids. Leucine supplementation does not attenuate skeletal muscle loss during leg immobilization in healthy, young men Backx, E.

Leucine supplementation does not attenuate skeletal muscle loss during leg immobilization in healthy, young men. Brain tissue plasticity: protein synthesis rates of the human brain Smeets, Joey S.

Brain tissue plasticity: protein synthesis rates of the human brain Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients Hansen, Dominique, Verboven, Kenneth, van Dijk, Jan Willem, Zorenc, Antoine H.

Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients.

Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats Monaco, Cynthia, Miotto, Paula M.

Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats.

American Journal of Physiology - Regulatory Integrative and Comparative Physiology. The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary disease Beijers, Rosanne J.

and Schols, Annemie M. The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary disease.

Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes Jonvik, Kristin L. Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes.

Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in patients with mitochondrial myopathy Nabben, Miranda, Schmitz, Joep P.

and Prompers, Jeanine J.. Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in patients with mitochondrial myopathy.

Detection of localized hepatocellular amino acid kinetics by using mass spectrometry imaging of stable isotopes Arts, Martijn, Soons, Zita, Ellis, Shane R. and Damink, Steven W. Detection of localized hepatocellular amino acid kinetics by using mass spectrometry imaging of stable isotopes.

Angewandte Chemie. Post-exercise muscle glycogen resynthesis in humans Burke, Louise M. Post-exercise muscle glycogen resynthesis in humans. The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: individual participant data and meta-analysis of rct's Tieland, Michael, Franssen, Rinske, Dullemeijer, C.

The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: individual participant data and meta-analysis of rct's. Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis Dirks, Marlou L.

Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis. Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans Snijders, Tim, Nederveen, Joshua P.

Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans. Physiological Reports. Postexercise muscle glycogen resynthesis in humans Burke, Louise, Van Loon, Luc and Hawley, John.

Postexercise muscle glycogen resynthesis in humans. Consideration of insects as a source of dietary protein for human consumption Churchward-Venne, T. Consideration of insects as a source of dietary protein for human consumption.

Protein supplementation augments muscle fiber hypertrophy but does not modulate satellite cell content during prolonged resistance-type exercise training in frail elderly Dirks, Marlou L. Protein supplementation augments muscle fiber hypertrophy but does not modulate satellite cell content during prolonged resistance-type exercise training in frail elderly.

Journal of the American Medical Directors Association JAMDA : long-term care: management, applied research and clinical issues. Glucose plus fructose ingestion for post exercise recovery greater than the sum of its parts?

Gonzalez, Javier T. Twenty-four-hour biological variation profiles of cardiac troponin I in individuals with or without chronic kidney disease Van Der Linden, Noreen, Hilderink, Judith M. and Meex, Steven J. Twenty-four-hour biological variation profiles of cardiac troponin I in individuals with or without chronic kidney disease.

Clinical Chemistry Washington, DC : international journal of molecular diagnostics and laboratory medicine. Dietary protein intake and distribution patterns of well-trained Dutch athletes Gillen, Jenna B. Dietary protein intake and distribution patterns of well-trained Dutch athletes.

Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice Dijk, Francina J. Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice.

Clinical Nutrition ESPEN. Extensive type ii muscle fiber atrophy in elderly female hip fracture patients Kramer, Irene F. Extensive type ii muscle fiber atrophy in elderly female hip fracture patients. The Journals of Gerontology: Series A. Fructose and sucrose intake increase exogenous carbohydrate oxidation during exercise Trommelen, Jorn, Fuchs, Cas J.

Fructose and sucrose intake increase exogenous carbohydrate oxidation during exercise. Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial Kouw, Imre W. Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial.

Sodium nitrate ingestion increases skeletal muscle nitrate content in humans Nyakayiru, Jean, Kouw, Imre W. Sodium nitrate ingestion increases skeletal muscle nitrate content in humans. Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men Tsintzas, Kostas, Stephens, F.

Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men.

Commentaries on Viewpoint: A time for exercise: the exercise window Boule, Normand G. Commentaries on Viewpoint: A time for exercise: the exercise window. No effect of acute and 6-day nitrate supplementation on VO2 and time-trial performance in highly trained cyclists Nyakayiru, Jean, Jonvik, Kristin L.

No effect of acute and 6-day nitrate supplementation on VO2 and time-trial performance in highly trained cyclists. Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position Holwerda, Andrew M.

Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position. Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players Nyakayiru, Jean, Jonvik, Kristin L.

Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players. Seasonal variation in vitamin d status in elite athletes: a longitudinal study Backx, E. and Mensink, M.. Seasonal variation in vitamin d status in elite athletes: a longitudinal study.

Glycemic control during consecutive days with prolongedwalking exercise in individuals with type 1 diabetes mellitus van Dijk, Jan Willem, Eijsvogels, Thijs M. and Van Loon, Lucas. Glycemic control during consecutive days with prolongedwalking exercise in individuals with type 1 diabetes mellitus.

Diabetes Research and Clinical Practice. May bed rest cause greater muscle loss than limb immobilization? Dirks, M. and van Loon, L..

Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: A feasibility study Rozenberg, Robert, Mankowski, Robert T. and Praet, Stephan F.

Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: A feasibility study. European Journal of Medical Research. Cardiac Troponin T and i Release after a km Run Klinkenberg, Lieke J.

Meex, Steven J. Cardiac Troponin T and i Release after a km Run. American Journal of Cardiology. Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population van der Linden, Noreen, Klinkenberg, Lieke J. Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population.

Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion Wall, Benjamin T. Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion.

Impact of diet composition on blood glucose regulation Russell, Wendy R. Impact of diet composition on blood glucose regulation. Critical Reviews in Food Science and Nutrition.

The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient Sipers, Walther M.

The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient. Journal of the American Medical Directors Association. Resistance training increases skeletal muscle capillarization in healthy older men Verdijk, Lex B.

Resistance training increases skeletal muscle capillarization in healthy older men. Habitual Dietary Nitrate Intake in Highly Trained Athletes Jonvik, Kristin L. Habitual Dietary Nitrate Intake in Highly Trained Athletes.

Protein intake and lean body mass preservation during energy intake restriction in overweight older adults Backx, E. Protein intake and lean body mass preservation during energy intake restriction in overweight older adults.

International Journal of Obesity. Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance-type exercise training Snijders, Tim, Smeets, Joey S.

Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance-type exercise training. Resistance exercise augments postprandial overnight muscle protein synthesis rates Trommelen, Jorn, Holwerda, Andrew M.

Resistance exercise augments postprandial overnight muscle protein synthesis rates. Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning Wall, Benjamin T.

Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning. Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction Klinkenberg, Lieke J.

Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction. Clinical Chemistry.

Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness Hangelbroek, Roland W. Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness.

Journal Cachexia Sarcopenia Muscle. The impact of 1-year vitamin D supplementation on vitamin D status in athletes: A dose-response study Backx, E. The impact of 1-year vitamin D supplementation on vitamin D status in athletes: A dose-response study. Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia Reginster, Jean Yves, Cooper, Cyrus, Rizzoli, Rene, Kanis, John A.

Cruz-Jentoft, Alfonso J.. Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clinical and Experimental Research. Hypoxia induces a prothrombotic state independently of the physical activity Ninivaggi, Marisa, De Laat, Marieke, Lancé, Marcus M.

Hypoxia induces a prothrombotic state independently of the physical activity. PLoS ONE. Prolonged adaptation to a low or high protein diet does not modulate basal muscle protein synthesis rates: A substudy Hursel, Rick, Martens, Eveline A.

Prolonged adaptation to a low or high protein diet does not modulate basal muscle protein synthesis rates: A substudy. Can elite athletes benefit from dietary nitrate supplementation? Jonvik, Kristin L. Exercise strategies to optimize glycemic control in type 2 diabetes: A continuing glucose monitoring perspective van Dijk, Jan Willem and Van Loon, Luc.

Exercise strategies to optimize glycemic control in type 2 diabetes: A continuing glucose monitoring perspective. Diabetes Spectrum. Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion Wall, Benjamin T.

Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion. Post-prandial protein handling: You are what you just ate Groen, Bart B.

Post-prandial protein handling: You are what you just ate. Dietary Protein as a Trigger for Metabolic Adaptation Van Loon, Luc. Dietary Protein as a Trigger for Metabolic Adaptation. Appetite levels and taste sensations typically decline with age. While this is a good natural balance to a slower metabolism, it can hinder the consumption of nutrient-rich foods.

If food seems bland and uninteresting, you are at risk of consuming a diet limited in vital vitamins and minerals. Aim to try new bold flavors and eat by need, not desire. This is especially important for endurance athletes spending hours sweating in hot, humid temperatures. Drink by time instead of thirst and check urine color light yellow means well-hydrated.

All those years of eating whatever you wanted has caught up to you in the form of gastric inflammation. The more inflamed your gut is, the less able it is to absorb nutrients from food. The best way to consume vitamins, minerals and phytonutrients is through a well-balanced, colorful diet.

Overall, masters athletes have a slightly different set of nutritional needs due mostly to declining energy needs and higher nutrient requirements. Supplements may help meet needs during this stage of life, but make sure to check with a doctor and dietitian before adding one to your daily regimen.

As a current professional road cyclist and previous elite marathoner and ultra-runner, Lori knows firsthand that food can enhance or diminish performance gains.

Scientists believe the body slowly down-regulates muscle protein synthesis signaling. Eating more protein will help reduce muscle loss or at least off-set this anabolic resistance.

For active people, researchers recommend a daily protein intake of 1. It is more practical, though, to work out your protein intake per meal.

Studies suggest this should be in the region of 0. The type of fat you consume may make a difference to your ability to build muscle. There is convincing evidence that, in terms of preserving muscle mass, omega-3s become more important as we get older. Low levels may reduce muscle function and strength and impair performance.

Getting adequate levels of vitamin D whether from sun exposure, diet or supplements becomes more important for optimal performance.

But if you are concerned about ingesting enough energy, you may find these tools useful. My favorite calculation is referred to as Mifflin-St. I use this calculation because unlike some of the other equations out there, Mifflin-St. Jeor more accurately represents caloric requirements of athletes and incorporates an activity factor.

With all nutrition-based calculations, experiment with what works for you and remember that a calculation will not always reflect your needs. First, calculate your Basal Metabolic Rate BMR; energy expenditure at rest. Second, multiply BMR by an activity factor see table below.

This is your estimated calorie requirement to support health, metabolic functionality and performance. A well-balanced diet is the cornerstone of good health. Consuming adequate carbohydrates, protein and fat, along with a variety of fruits and vegetables, sustains energy levels, mental health, body system functionality and general wellbeing.

Although a balanced diet is essential to long-term health, protein is especially important for the aging athlete. Muscle protein synthesis MPS is normally stimulated in response to protein consumption or exercise.

In older adults, these stimuli are impaired, thereby reducing MPS. Studies have indicated that 40 grams of high-quality protein, such as whey, eggs or pea protein is an optimal dose for anabolic stimulation in older athletes.

Doses of 20 to 30 grams may be more appropriate for younger athletes. I always take a food-first approach when it comes to both macro- and micronutrient requirements. But supplements are great to help support what we often lack in our diets.

Oftentimes I suggest key foods to clients to boost a specific nutrient. If more support is needed, I recommend supplemental nutrient forms. Supplements are especially useful when we age due to reduced nutrient absorption.

Make sure you are ingesting enough protein to support MPS. Protein powders both whey and plant-based provide high-quality protein and boost what may be lacking in the diet. Collagen supplementation can help improve collagen synthesis, which may help reduce risk of injury to connective tissues.

Take these before or during your training or performance sessions. Ingestion can help stimulate MPS and reduce delayed onset muscle soreness DOMS. Eat enough calories and macronutrients.

Calorie restriction causes porous bones. Instead I recommend optimizing calcium levels by consuming canned salmon, yogurt, seeds, beans, Chinese cabbage and molasses.

Additionally, most people do not meet daily vitamin D needs due to insufficient sun exposure. Discuss any supplements with your primary care doctor before beginning a new regimen as some may not be appropriate for you.

To continue training and performing throughout your life, take care of your wellbeing. Below are a few recommendations.

You are less likely to see an incremental decline with age by maintaining a level of performance. Maintaining flexibility in addition to strength will help you stay limber. Stretching also increases blood flow, which helps the healing process. Become aware of how your body feels during your training and performance sessions.

If you are approaching your absolute limits on a continuous basis, consider reducing your workload to protect your body from injury. You may find that you need more rest days in order to bounce back. Routinely visit a doctor regardless of your age. Check for any trends or patterns with blood work.

Staying on top of your basic health helps identify problems early on so they can be addressed. As we age, metabolic and physiologic changes are inevitable. Preparing for these changes by taking care of ourselves throughout the various stages of our lives will ensure that we continue performing at peak levels.

We can best prepare for the future by improving our nutrition, lifestyle and recovery techniques. In order to continue doing what we love, we must take care of ourselves! Gaby, A. Nutritional Medicine. Fritz Perlberg Publishing: Concord, NH.

doi: Caitlin Holmes is a Certified Nutrition Specialist CNS. After graduating, she started her nutrition coaching business, Caitlin Holmes Nutrition, LLC, where she primarily works with climbers and outdoor enthusiasts to develop effective nutrition plans for long-term health and performance.

She believes that nutrition is a powerful tool for athletes and that eating well plays a major role in achieving goals, preventing injuries, and supporting the body to continue performing for years to come! Shop All. Shop By Usage.

Everyday Products. Pre-Workout Products. Performance Products. Recovery Products. Shop By Activity. Shop By Function. Gear and Accessories. Refer a Friend. Get Started. The Gnarly System. Our Story. Our Athletes. Media Reviews. Find local retailer. Caitlin Holmes December 21, Longevity in Sport: Nutrition through the Ages Aging is a natural part of life, but aging does not have to be a barrier to performance.

What happens when we age? Nutritional support for longevity in sports. Jeor Equation:. Level of Activity Activity Factor Sedentary 1. Supplementation and key foods. Branched-chain amino acids BCAAs. Potato protein ingestion increases muscle protein synthesis rates at rest and during recovery from exercise in humans.

Twist2-expressing cells reside in human skeletal muscle and are responsive to aging and resistance exercise training Gaulton, Nick, Wakelin, Griffen, Young, Laura V.

Twist2-expressing cells reside in human skeletal muscle and are responsive to aging and resistance exercise training. The FASEB Journal. Article e Skeletal Muscle Fibre Characteristics of the Lumbar Multifidus Muscle in Patients Undergoing Microdiscectomy for Unilateral Lumbar Disc Herniation Stevens, S, Agten, A, Snijders, T, Plazier, M, Bamps, S, Assieker, T, Betz, M, Timmermans, A, Van Loon, Lucas and Vandenabeele, F.

Skeletal Muscle Fibre Characteristics of the Lumbar Multifidus Muscle in Patients Undergoing Microdiscectomy for Unilateral Lumbar Disc Herniation. Muscle, Ligaments and Tendons Journal MLTJ. Dietary nitrate increases submaximal SERCA activity and ADP-transfer to mitochondria in slow-twitch muscle of female mice Petrick, Heather, Brownell, Stuart, Vachon, Bayley, Brunetta, Henver, Handy, Rachel, Van Loon, Lucas, Murrant, Coral and Holloway, Graham.

Dietary nitrate increases submaximal SERCA activity and ADP-transfer to mitochondria in slow-twitch muscle of female mice. American Journal of Physiology: Endocrinology and Metabolism.

Raw eggs to support post-exercise recovery in healthy young men : Did Rocky get it right or wrong? Fuchs, Cas J. Skeletal muscles of patients infected with SARS-CoV-2 develop severe myofiber damage upon one week of admission on the intensive care unit Stevens, Sjoerd, Hendrickx, Paul, Snijders, Tim, Lambrichts, Ivo, Stessel, Björn, Dubois, Jasperina, van Loon, Lucas J.

Skeletal muscles of patients infected with SARS-CoV-2 develop severe myofiber damage upon one week of admission on the intensive care unit. Applied Sciences. Ingestion of an ample amount of meat substitute based on a lysine-enriched,plant-based protein blend stimulates postprandial muscle proteinsynthesis to a similar extent as an isonitrogenous amount of chickenin healthy, young men Kouw, Imre W.

Ingestion of an ample amount of meat substitute based on a lysine-enriched,plant-based protein blend stimulates postprandial muscle proteinsynthesis to a similar extent as an isonitrogenous amount of chickenin healthy, young men.

British Journal of Nutrition. Nutritional strategies to attenuate postprandial glycemic response Pasmans, Kenneth, Meex, Ruth C. and Blaak, Ellen E.. Nutritional strategies to attenuate postprandial glycemic response. Obesity Reviews. Exercise-based interventions to counteract skeletal muscle mass loss in people with cancer : Can we overcome the odds?

Bland, Kelcey A. and Fairman, Ciaran M.. Sports Medicine. The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling : A narrative review Holwerda, Andrew M. The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling : A narrative review.

Nutrition Reviews. Impact of magnesium on bone health in older adults : A systematic review and meta-analysis Groenendijk, Inge, van Delft, Marieke, Versloot, Pieter, van Loon, Luc J.

Impact of magnesium on bone health in older adults : A systematic review and meta-analysis. L-arabinose co-ingestion delays glucose absorption derived from sucrose in healthy men and women : A double-blind, randomized crossover trial Pasmans, Kenneth, Meex, Ruth C. L-arabinose co-ingestion delays glucose absorption derived from sucrose in healthy men and women : A double-blind, randomized crossover trial.

Amino acid removal during hemodialysis can be compensated for by protein ingestion and is not compromised by intradialytic exercise : A randomized controlled crossover trial Hendriks, Floris K. Amino acid removal during hemodialysis can be compensated for by protein ingestion and is not compromised by intradialytic exercise : A randomized controlled crossover trial.

American Journal of Clinical Nutrition. Fragile bones of elite cyclists : To treat or not to treat? Hilkens, Luuk, Knuiman, Pim, Heijboer, Mathieu, Kempers, Robert, Jeukendrup, Asker E. and van Dijk, Jan-Willem.

Journal of Applied Physiology. Gut amino acid absorption in humans : Concepts and relevance for postprandial metabolism Trommelen, Jorn, Tomé, Daniel and van Loon, Luc J. Gut amino acid absorption in humans : Concepts and relevance for postprandial metabolism. Clinical Nutrition Open Science.

Comprehensive assessment of post-prandial protein handling by the application of intrinsically labelled protein in vivo in human subjects Trommelen, Jorn, Holwerda, Andrew M.

and van Loon, Lucas J. Comprehensive assessment of post-prandial protein handling by the application of intrinsically labelled protein in vivo in human subjects. Proceedings of the Nutrition Society. Dietary protein interventions to improve nutritional status in end-stage renal disease patients undergoing hemodialysis Hendriks, Floris K.

Dietary protein interventions to improve nutritional status in end-stage renal disease patients undergoing hemodialysis. Current Opinion in Clinical Nutrition and Metabolic Care. A white paper on collagen hydrolyzates and ultrahydrolyzates : Potential supplements to support joint health in osteoarthritis?

Mobasheri, Ali, Mahmoudian, Armaghan, Kalvaityte, Ursule, Uzieliene, Ilona, Larder, Christina E. and Zuscik, Michael J..

Current Rheumatology Reports. The anabolic response to plant-based protein ingestion Pinckaers, Philippe J. The anabolic response to plant-based protein ingestion. Hepatic steatosis contributes to the development of muscle atrophy via inter-organ crosstalk Pasmans, Kenneth, Adriaens, Michiel E.

Olde, Caiment, Florian, van Loon, Luc J. and Meex, Ruth C. Hepatic steatosis contributes to the development of muscle atrophy via inter-organ crosstalk. Frontiers in Endocrinology. Acute effects of dietary nitrate on exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease van der Avoort, Cindy M.

and Hopman, Maria T. Acute effects of dietary nitrate on exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease.

International Journal of Sport Nutrition and Exercise Metabolism. Mass spectrometry imaging of L-[ring C6]- labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma Cao, Jianhua, Balluff, Benjamin, Arts, Martijn, Dubois, Ludwig J.

and Heeren, Ron M. Mass spectrometry imaging of L-[ring C6]- labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma. Insects are a viable protein source for human consumption : From insect protein digestion to postprandial muscle protein synthesis in vivo in humans : A double-blind randomized trial Hermans, Wesley J.

Insects are a viable protein source for human consumption : From insect protein digestion to postprandial muscle protein synthesis in vivo in humans : A double-blind randomized trial. Increasing nitrate-rich vegetable intake lowers ambulatory blood pressure in pre hypertensive middle-aged and older adults : A wk randomized controlled trial van der Avoort, Cindy M.

Increasing nitrate-rich vegetable intake lowers ambulatory blood pressure in pre hypertensive middle-aged and older adults : A wk randomized controlled trial.

Undeclared doping substances are highly prevalent in commercial sports nutrition supplements Duiven, Erik, Luc J. van Loon, Spruijt, Laila, Koert, Willem and de Hon, Olivier M..

Undeclared doping substances are highly prevalent in commercial sports nutrition supplements. Journal of Sports Science and Medicine.

No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males Pinckaers, Philippe J.

No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males.

Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial Murphy, Caoileann H.

and Roche, Helen M.. A randomized, double-blind, placebo-controlled trial. Daily myofibrillar protein synthesis rates in response to low- And high-frequency resistance exercise training in healthy, young men Shad, Brandon J.

and Wallis, Gareth A.. Daily myofibrillar protein synthesis rates in response to low- And high-frequency resistance exercise training in healthy, young men. Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle Smeets, Joey S.

Olde, Schijns, Olaf E. Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle. Journal of Cachexia, Sarcopenia and Muscle.

Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults Snijders, Tim, Holwerda, Andy M. and Verdijk, Lex B..

Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults.

Acta Physiologica. The impact of beetroot juice supplementation on muscular endurance, maximal strength and countermovement jump performance Jonvik, Kristin L. The impact of beetroot juice supplementation on muscular endurance, maximal strength and countermovement jump performance. European Journal of Sport Science.

Assessing the whole-body protein synthetic response to feeding in vivo in human subjects Trommelen, Jorn and Van Loon, Luc J. Assessing the whole-body protein synthetic response to feeding in vivo in human subjects. Exercise plus presleep protein ingestion increases overnight muscle connective tissue protein synthesis rates in healthy older men Holwerda, Andrew M.

Exercise plus presleep protein ingestion increases overnight muscle connective tissue protein synthesis rates in healthy older men. Whey protein supplementation does not accelerate recovery from a single bout of eccentric exercise Hilkens, Luuk, De Bock, Jolien, Kretzers, Joris, Kardinaal, Alwine F.

Whey protein supplementation does not accelerate recovery from a single bout of eccentric exercise. Applied Physiology, Nutrition and Metabolism. Muscle fiber capillarization is associated with various indices of skeletal muscle mass in healthy, older men Betz, M.

and Snijders, T.. Muscle fiber capillarization is associated with various indices of skeletal muscle mass in healthy, older men. Experimental Gerontology. Higher levels of physical activity are associated with greater fruit and vegetable intake in older adults Van Loon, L..

Higher levels of physical activity are associated with greater fruit and vegetable intake in older adults.

Journal of Nutrition, Health and Aging. Dietary protein intake does not modulate daily myofibrillar protein synthesis rates of loss of muscle mass and function during short-term immobilization in young men : a randomized controlled trial Kilroe, Sean Paul, Fulford, Jonathan, Jackman, Sarah, Holwerda, Andrew, Gijsen, Annemie, van Loon, Luc and Wall, Benjamin Toby.

Dietary protein intake does not modulate daily myofibrillar protein synthesis rates of loss of muscle mass and function during short-term immobilization in young men : a randomized controlled trial. The American Journal of Clinical Nutrition.

Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight and obese men Tsintzas, Kostas, Jones, Robert, Pabla, Pardeep, Mallinson, Joanne, Barrett, David A.

and Stephens, Francis B.. Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight and obese men. American Journal of Physiology - Endocrinology and Metabolism.

In vitro ketone-supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle Petrick, Heather L. and Holloway, Graham P.. In vitro ketone-supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle.

The Journal of Physiology. Casein ingestion does not increase muscle connective tissue protein synthesis rates Trommelen, Jorn, Holwerda, Andrew M. Casein ingestion does not increase muscle connective tissue protein synthesis rates.

The glycation level of milk protein strongly modulates post-prandial lysine availability in humans Nyakayiru, Jean, van Lieshout, Glenn A. The glycation level of milk protein strongly modulates post-prandial lysine availability in humans. The concept of skeletal muscle memory : Evidence from animal and human studies Snijders, Tim, Aussieker, Thorben, Holwerda, Andy, Parise, Gianni, van Loon, Luc J.

The concept of skeletal muscle memory : Evidence from animal and human studies. Temporal muscle-specific disuse atrophy during one week of leg immobilization Kilroe, Sean P. and Wall, Benjamin T.. Temporal muscle-specific disuse atrophy during one week of leg immobilization.

Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission Dirks, Marlou L. Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission.

Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans Gorissen, Stefan H.

Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans. Postexercise cooling impairs muscle protein synthesis rates in recreational athletes Fuchs, Cas J.

van Marken, Verdijk, Lex B. Postexercise cooling impairs muscle protein synthesis rates in recreational athletes. Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise Ian Rollo, Javier T. Gonzalez, Cas J. Fuchs, Lucas Van Loon and Clyde Williams.

Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise. PRESENT Text Expanding on the Checklist for Proper Reporting of Evidence in Sport and Exercise Nutrition Trials James A.

Betts, Javier T. Gonzalez, Louise Burke, Graeme L. Close, Ina Garthe, Lewis J James, Asker E Jeukendrup, James P. Morton, David C Nieman, Peter Peeling, Stuart M Phillips, Trent Stellingwerff, Lucas Van Loon, Clyde Williams, Kathleen Woolf, Ronald J.

Maughan and Greg Atkinson. PRESENT Text Expanding on the Checklist for Proper Reporting of Evidence in Sport and Exercise Nutrition Trials. Mitochondrial ROS and Aging: Understanding Exercise as a Preventive Tool Henver S Brunetta, Andrew M Holwerda, Luc Van Loon and Graham P Holloway.

Mitochondrial ROS and Aging: Understanding Exercise as a Preventive Tool. Journal of Science in Sport and Exercise. Impact of whole dairy matrix on musculoskeletal health and aging—current knowledge and research gaps N.

Geiker, C. Mølgaard, S. Iuliano, R. Rizzoli, Y. Manios, L. van Loon, J. Lecerf, G. Moschonis, J. Reginster, I. Givens and A. Impact of whole dairy matrix on musculoskeletal health and aging—current knowledge and research gaps.

Osteoporosis International. Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest Gonzalez, Javier T. Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest. European Journal of Applied Physiology.

Impact of exercise-nutritional state interactions in patients with type 2 diabetes Verboven, Kenneth, Wens, Inez, Vandenabeele, Frank, Stevens, An, Celie, Bert, Lapauw, Bruno, Dendale, Paul, van Loon, Luc J. Impact of exercise-nutritional state interactions in patients with type 2 diabetes.

Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review Jean Nyakayiru, Luc Van Loon and Lex B. A mini-review.

Hot-water immersion does not increase postprandial muscle protein synthesis rates during recovery from resistance-type exercise in healthy, young males Fuchs, Cas J. Hot-water immersion does not increase postprandial muscle protein synthesis rates during recovery from resistance-type exercise in healthy, young males.

Endurance-type exercise increases bulk and individual mitochondrial protein synthesis rates in rats Holwerda, Andrew M. Endurance-type exercise increases bulk and individual mitochondrial protein synthesis rates in rats. End-stage renal disease patients lose a substantial amount of amino acids during hemodialysis Hendriks, Floris K.

End-stage renal disease patients lose a substantial amount of amino acids during hemodialysis. Nutrition in Clinical Practice. Dose-response effects of dietary protein on muscle protein synthesis during recovery from endurance exercise in young men : A double-blind randomized trial Churchward-Venne, Tyler A.

Dose-response effects of dietary protein on muscle protein synthesis during recovery from endurance exercise in young men : A double-blind randomized trial. Casein protein processing strongly modulates post-prandial plasma amino acid responses in vivo in humans Trommelen, Jorn, Weijzen, Michelle E.

Casein protein processing strongly modulates post-prandial plasma amino acid responses in vivo in humans. A nitrate-rich vegetable intervention elevates plasma nitrate and nitrite concentrations and reduces blood pressure in healthy young adults van der Avoort, Cindy M.

A nitrate-rich vegetable intervention elevates plasma nitrate and nitrite concentrations and reduces blood pressure in healthy young adults. Journal of the Academy of Nutrition and Dietetics.

Voeding bij intensieve sportbeoefening van Loon, L. and Saris, W. Voeding bij intensieve sportbeoefening.

In In Former, Majorie, van Asseldonk, Gerdie, Drenth, Jacqueline and Schuurman, Caroelien Ed. Informatorium voor Voeding en Dietetiek - Supplement - December pp. Short-term muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates Kilroe, Sean P.

Short-term muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates. The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation Jorn Trommelen, Andrew M.

Holwerda, Jean Nyakayiru, Stefan H M Gorissen, Olav Rooyackers, Nicholas A Burd, Yves Boirie and Luc J. Van Loon. The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation.

Fructose co-ingestion to increase carbohydrate availability in athletes Cas J. Fuchs, Javier T. Gonzalez and Luc J. Fructose co-ingestion to increase carbohydrate availability in athletes. Dietary Protein and Physical Activity Interventions to Support Muscle Maintenance in End-Stage Renal Disease Patients on Hemodialysis Floris K.

Hendriks, Joey S J Smeets, Frank M van der Sande, Jeroen P Kooman and Lucas Van Loon. Dietary Protein and Physical Activity Interventions to Support Muscle Maintenance in End-Stage Renal Disease Patients on Hemodialysis. The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise Jorn Trommelen, Milan W Betz and Luc Van Loon.

The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise. Exercising to offset muscle mass loss in hemodialysis patients: The disconnect between intention and intervention Colleen F. McKenna, Amadeo F. Salvador, Floris K. Hendriks, Alana P. Harris, Luc J. Van Loon and Nicholas A.

Exercising to offset muscle mass loss in hemodialysis patients: The disconnect between intention and intervention. Seminars in Dialysis. Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients Irene Fleur Kramer, Taco J.

Blokhuis, Lex B. Verdijk, Luc Van Loon and Martijn Poeze. Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients. One week of step reduction lowers myofibrillar protein synthesis rates in young men Shad, Brandon J. One week of step reduction lowers myofibrillar protein synthesis rates in young men.

Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men Holwerda, Andrew M. Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men.

Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest Dirks, Marlou L. Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest.

Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse Kneppers, Anita, Leermakers, Pieter, Pansters, Nicholas, Backx, Evelien, Gosker, Harry, van Loon, Luc, Schols, Annemie, Langen, Ramon and Verdijk, Lex.

Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse. Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men Vliet, Stephan Van, Beals, Joseph W. and Burd, Nicholas A..

Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men. Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross-over trial Mason, Shaun A.

Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross-over trial.

Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics. Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2O2 emission rates in human skeletal muscle Petrick, Heather L.

Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2O2 emission rates in human skeletal muscle. The effect of minimally invasive surgical aortic valve replacement on postoperative pulmonary and skeletal muscle function Boujemaa, Hajar, Yilmaz, Alaaddin, Robic, Boris, Koppo, Katrien, Claessen, Guido, Frederix, Ines, Dendale, Paul, Völler, Heinz, van Loon, Luc J.

and Hansen, Dominique. The effect of minimally invasive surgical aortic valve replacement on postoperative pulmonary and skeletal muscle function. Experimental Physiology. In In A. Holwerda Ed.

Dietary protein to support active aging pp. The effect of beetroot juice supplementation on dynamic apnea and intermittent sprint performance in elite female water polo playres Jonvik, Kristin L.

The effect of beetroot juice supplementation on dynamic apnea and intermittent sprint performance in elite female water polo playres. Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle Holloway, Graham P. Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle.

Cell Reports. Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men Holwerda, Andrew M. Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men. Temporal response of angiogenesis and hypertrophy to resistance training in young men Holloway, Tanya M.

Temporal response of angiogenesis and hypertrophy to resistance training in young men. Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates Langer, Henning, Senden, Joan M.

Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates. Frontiers in Physiology. Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[c]-leucine PET Smeets, Joey S. J and Van Loon, Luc.

Reply: measurement of regional rates of protein synthesis in human brain in vivo with l-[c]-leucine PET. Brain: a journal of neurology. Skeletal muscle fiber characteristics in patients with chronic heart failure: Impact of disease severity and relation with muscle oxygenation during exercise Niemeijer, Victor M.

Skeletal muscle fiber characteristics in patients with chronic heart failure: Impact of disease severity and relation with muscle oxygenation during exercise. Dose-response effects of supplementation with calcifediol on serum hydroxyvitamin D status and its metabolites: a randomized controlled trial in older adults Vaes, Anouk M.

Dose-response effects of supplementation with calcifediol on serum hydroxyvitamin D status and its metabolites: a randomized controlled trial in older adults. Clinical Nutrition. Increasing vegetable intake to obtain the health promoting and ergogenic effects of dietary nitrate Van der Avoort, Cindy M.

Increasing vegetable intake to obtain the health promoting and ergogenic effects of dietary nitrate. European Journal of Clinical Nutrition. Effects of creatine and carbohydrate loading on cycling time trial performance Tomcik, Kristyen A. Effects of creatine and carbohydrate loading on cycling time trial performance.

IOC consensus statement: dietary supplements and the high-performance athlete Maughan, Ronald J. Engebretsen, Lars.