Subcutaneous fat and heart disease risks -
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Role of TNF-alpha in vascular dysfunction. Clin Sci Lond. Download references. Federal State Budgetary Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation.
Federal State Budget Educational Institution of Higher Education, Kemerovo State Medical University of the Ministry of Healthcare of the Russian Federation, Kemerovo, Russian Federation.
Autonomous Public Healthcare Institution of the Kemrovo Region, Kemerovo Regional Clinical Hospital named after S.
Beliyaev, Regional Center for Diabetes, Kemerovo, Russian Federation. You can also search for this author in PubMed Google Scholar. OG and OB wrote and revised the manuscript, DB and YD collected and reviewed the literature.
All authors read and approved the final manuscript. Correspondence to Evgenya Uchasova. The Ethics Committee of the Federal State Budgetary Institution, Research Institute for Complex Issues of Cardiovascular Diseases approved this study protocol No.
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Reprints and permissions. Gruzdeva, O. et al. Localization of fat depots and cardiovascular risk. Lipids Health Dis 17 , Download citation. Received : 12 June Accepted : 28 August Published : 15 September Anyone you share the following link with will be able to read this content:.
Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. Download PDF. Abstract Despite the existing preventative and therapeutic measures, cardiovascular diseases remain the main cause of temporary disability, long-term disability, and mortality.
Background Despite the existing preventative and therapeutic measures, cardiovascular diseases CVD remain the main cause of temporary disability and mortality [ 1 ].
Table 1 The relationship between various depots of fat and cardiovascular diseases Full size table. Conclusion It is known that each local fat depot can be considered an independent endocrine organ that actively produces biologically active molecules, such as pro- and anti-inflammatory cytokines and adipokines.
Mechanisms of various ectopic fats related with cardiovascular deseases. Full size image. Abbreviations BMI: Body mass index CAD: Coronary artery disease CT: Computed tomography CVD: Cardiovascular diseases EAT: Epicardial adipose tissue FFA: Free fatty acids IR: Insulin resistance MS: Metabolic syndrome NAFLD: Non-alcoholic fatty liver disease NASH: Alcoholic steatohepatitis PVAT: Perivascular adipose tissue SAT: Subcutaneous adipose tissue VAT: Visceral adipose tissue VO: Visceral obesity.
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You don't need to go to the gym and change your clothes," she says. Just being physically active can help improve your metabolic health. Even getting up to walk around periodically during work can be beneficial.
Regular physical activity may not always help you lose weight, but again, it can help you maintain a healthy weight, and also improve blood sugar for people with diabetes.
Having a higher proportion of muscle mass can help you burn more calories, so adding strength training at least twice a week, focusing on all the major muscle groups, may also help you maintain your weight.
Unfortunately, avoiding weight gain around the middle may be easier for some women than others, as some people are simply more prone to adding extra pounds in the belly. Research may one day help to uncover new ways to head off this dangerous type of fat and, in turn, reduce the risk for diabetes and cardiovascular disease.
Certain newer medications used to treat people with diabetes — known as sodium-linked glucose transport inhibitors — have the interesting side effect of inducing weight loss and reducing visceral fat, says Dr.
In the meantime, focus on lifestyle changes and exercise, and keep an eye on your belt buckle to gauge your progress. Kelly Bilodeau , Former Executive Editor, Harvard Women's Health Watch. As a service to our readers, Harvard Health Publishing provides access to our library of archived content.
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Stay on top of latest health news from Harvard Medical School. Recent Blog Articles. Worldwide, around 3 billion people are overweight or have obesity.
The "obesity epidemic contributes significantly" to many chronic health conditions and cardiovascular disease cases around the world, Powell-Wiley said. Specifically, obesity is associated with a higher risk of coronary artery disease and death from cardiovascular disease.
It contributes to high cholesterol, Type 2 diabetes, high blood pressure and sleep disorders. Yet some people whose BMI classifies them as obese, but who have low levels of abdominal fat, are at lower risk for heart problems, the analysis showed.
Meeting federal guidelines for minutes of physical activity per week may be sufficient to reduce abdominal fat, the analysis found, with no additional loss from longer activity times.
Exercise alone or in combination with diet changes have been shown in some instances to reduce abdominal obesity even without weight loss. Also, weight loss from lifestyle changes improves blood sugar, blood pressure, and triglyceride and cholesterol levels — a cluster of factors referred to as metabolic syndrome, according to the new statement.
It also reduces inflammation, improves blood vessel function and helps non-alcoholic fatty liver disease. In addition, intense weight loss may help curb atrial fibrillation , a quivering or irregular heartbeat, according to the report.
Estimates suggest obesity may account for one-fifth of all cases. The new scientific statement evaluated research on managing and treating obesity, particularly abdominal obesity. Experts concluded that reducing calories and aerobic exercise were the most beneficial.
Obesity, traditionally measured using Greek yogurt toppings mass Mental focus and stress management BMIhas been haert cornerstone for predicting heaart and cardiovascular CV risk. Recently, Hearr et al. Qnd sex differences in the associations of computed tomography CT — based versus anthropometric measures of adiposity with cardiometabolic and CV risk in 3, Framingham Heart Study FHS participants. Over a mean follow-up of In women, however, VAT demonstrated much stronger associations with cardiometabolic and CV outcomes compared with BMI or waist circumference. Conflict of Mental focus and stress management Dissase Lopez-Jimenez has irsks relevant financial disclosures. Disrase Wael Almahmeed has no relevant financial disclosures. Dr Harold Natural digestion remedies has served as a speaker for Novo Subcutaneous fat and heart disease risks. Professor Emanuele Di Angelantonio has no relevant financial disclosures. Professor Carel le Roux reports grants from the Irish Research Council, Science Foundation Ireland, Anabio and the Health Research Board. He served on advisory boards of Novo Nordisk, Herbalife, GI Dynamics, Eli Lilly, Johnson and Johnson, Sanofi Aventis, Astra Zeneca, Janssen, Bristol-Myers Squibb, Boehringer-Ingelheim and Keyron.
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