Dodd SL, Johnson CA, Fernholz K, St Cyr JA. The role of ribose in human skeletal muscle metabolism. Med Hypotheses. Hellsten Y, Skadhauge L, Bangsbo J.

Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. Am J Physiol Regul Integr Comp Physiol. Seifert JG, Brumet A, St Cyr JA.

The influence of D-ribose ingestion and fitness level on performance and recovery. J Int Soc Sport Nutr. Seifert JG, Subudhi AW, Fu MX. The role of ribose on oxidative stress during hypoxic exercise: a pilot study. J Med Food. Kerksick C, Rasmussen C, Bowden R, Leutholtz B, Harvey T, Earnest C, et al.

Effects of ribose supplementation prior to and during intense exercise on anaerobic capacity and metabolic markers. Int J Sport Nutr Exe. Kreider RB, Melton C, Greenwood M, Rasmussen C, Lundberg J, Earnest C, et al. Effects of oral D-ribose supplementation on anaerobic capacity and selected metabolic markers in healthy males.

Eijnde BO, Van Leemputte M, Brouns F, Van Der Vusse GJ, Labarque V, Ramaekers M, et al. No effects of oral ribose supplementation on repeated maximal exercise and de novo ATP resynthesis.

J Appl Physiol. Seifert J, Frelich A, Shecterle L, Cyr JS. Assessment of hematological and biochemical parameters with extended D-ribose ingestion. Gross M, Zöllner N. Serum levels of glucose, insulin, and C-peptide during long-term D-ribose administration in man. Gross M, Reiter S, Zöllner N.

Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Aura O, Komi PV. The mechanical efficiency of locomotion in men and women with special emphasis on stretch-shortening cycle exercises.

Eur J Appl Physiol Occup Physiol. Jamurtas AZ, Fatouros IG, Buckenmeyer P, Kokkinidis E, Taxildaris K, Kambas A, et al. Effects of plyometric exercise on muscle soreness and plasma creatine kinase levels and Iits comparison with eccentric and concentric exercise.

Miyama M, Nosaka K. Influence of surface on muscle damage and soreness induced by consecutive drop jumps.

Leung AWS, Chan CCH, Lee AHS, Lam KWH. Visual analogue scale correlates of musculoskeletal fatigue. Percept Motor Skills. Price DD, Mcgrath PA, Rafii A, Buckingham B. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Bijur PE, Silver W, Gallagher EJ.

Reliability of the visual analog scale for measurement of acute pain. Acad Emerg Med. Kaya D, Citaker S, Kerimoglu U, Atay OA, Nyland J, Callaghan M, et al. Women with patellofemoral pain syndrome have quadriceps femoris volume and strength deficiency.

Knee Surg Sport Tr A. Arazi H, Asadi A, Chegini J. Perceived muscle soreness, functional performance and cardiovascular responses to an acute bout of two plyometric exercises. Int Sportmed J. Karoline C, Patria H, Linda M. Delayed onset muscle soreness: treatment strategies and performance factors.

Nosaka K, Clarkson PM, Apple FS. Time course of serum protein changes after strenuous exercise of the forearm flexors. J Lab Clin Med. Tofas T, Jamurtas AZ, Fatouros I, Nikolaidis MG, Koutedakis Y, Sinouris EA, et al. Plyometric exercise increases serum indices of muscle damage and collagen breakdown.

Erick D, Janne A, Masaki I, Jouni K, Sami K, Heikki KL, et al. Bimodal recovery pattern in human skeletal muscle induced by exhaustive stretch-shortening cycle exercise.

Kelly FJ. Use of antioxidants in the prevention and treatment of disease. J Int Fed Clin Chem. Download references. The authors would like to sincerely thank the participants for volunteered participating in this study and Professor Jørgen Jensen for critically reviewing the manuscript.

Department of Exercise Biochemistry, Exercise Science School, Beijing Sport University, No. Department of Nutrition, Georgia State University, Atlanta, GA, USA. Center for the Study of Human Health, Emory University, Atlanta, GA, USA.

China Athletics College, Beijing Sport University, Beijing, BJ, China. You can also search for this author in PubMed Google Scholar. WC was responsible for data collection, data interpretation, writing and revision of the manuscript, under the direction and assistance of JQ who assisted with each step and completion of the manuscript.

TC and LY assisted in the data collection and data interpretation. DB assisted in the revision of the manuscript. MZ assisted in the completion of the manuscript. The authors declare no conflict of interests with the current publication, and all authors approved the final version of the manuscript.

Correspondence to Junqiang Qiu. The research proposal was approved by the Institutional Review Board of Beijing Sport University BSU IRB and all participants gave written informed consent prior to study participation. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Open Access This article is licensed under a Creative Commons Attribution 4. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material.

If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Reprints and permissions.

Cao, W. et al. Effect of D-ribose supplementation on delayed onset muscle soreness induced by plyometric exercise in college students. J Int Soc Sports Nutr 17 , 42 Download citation. Received : 02 November Accepted : 02 August Published : 10 August Anyone you share the following link with will be able to read this content:.

Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative.

Skip to main content. Search all BMC articles Search. Download PDF. Research article Open access Published: 10 August Effect of D-ribose supplementation on delayed onset muscle soreness induced by plyometric exercise in college students Wei Cao 1 , Junqiang Qiu ORCID: orcid.

Abstract Objective Previous investigations suggest that appropriate nutritional interventions may reduce delayed onset muscle soreness DOMS. Methods For the purpose of inducing DOMS, 21 untrained male college students performed a lower-limb plyometric exercise session that involved 7 sets of 20 consecutive frog hops with s of rest between each set.

Conclusion D-ribose supplementation reduces muscle soreness, improves recovery of muscle damage, and inhibits the formation of lipid peroxides. Introduction Delayed onset muscle soreness DOMS is described as ultrastructural muscle damage that occurs following exercise, and is characterized by localized muscular tenderness and soreness [ 1 ].

Methods Subjects Twenty-one untrained healthy male college students volunteered as subjects for this study. Study design Participating subjects were asked to complete the Physical Activity Readiness Questionnaire and were measured for height and weight.

Experimental design. Full size image. Results All subjects completed the two plyometric exercise sessions and tests.

Discussion The purpose of this study was to explore whether timed D-ribose supplementation could reduce DOMS-associated factors and help to speed DOMS recovery.

Limitation It is a limitation that the study was not a double-blind cross-over study. Conclusion D-ribose supplementation may safely help to alleviate DOMS induced by plyometric exercise in the general population. Abbreviations DOMS: Delayed onset muscle soreness DRIB: D-ribose group PLAC: Placebo group ROS: Reactive oxygen species ATP: Adenosine triphosphate PPP: Pentose phosphate pathway CK: Creatine kinase LDH: Lactate dehydrogenase MB: Myoglobin SOD: Superoxide dismutase T-AOC: Total antioxidant capacity MDA: Malondialdehyde FPT: Flexor peak torque EPT: Extensor peak torque FTW: Flexor total work ETW: Extensor total work.

References Safran MR, Seaber AV, Garrett WE. CAS PubMed Google Scholar Armstrong RB. CAS PubMed Google Scholar Hody S, Croisier JL, Bury T, Rogister B, Leprince P. PubMed PubMed Central Google Scholar Newham DJ, McPhail G, Mills KR, Edwards RH.

CAS PubMed Google Scholar Fridén J, Sjöström M, Ekblom B. PubMed Google Scholar Fridén J, Lieber RL. Google Scholar Tiidus PM. CAS Google Scholar Hyldahl RD, Hubal MJ. PubMed Google Scholar Kim J, Lee J. Iwashita A , Tojo N , Matsuura S , Yamazaki S , Kamijo K , Ishida J , Yamamoto H , Hattori K , Matsuoka N , Mutoh S J Pharmacol Exp Ther , 2 , 09 Apr Cited by: 55 articles PMID: Caffeine metabolites are inhibitors of the nuclear enzyme poly ADP-ribose polymerase-1 at physiological concentrations.

Geraets L , Moonen HJ , Wouters EF , Bast A , Hageman GJ Biochem Pharmacol , 72 7 , 25 Jul Cited by: 53 articles PMID: Novel alkoxybenzamide inhibitors of poly ADP-ribose polymerase. Menear KA , Adcock C , Alonso FC , Blackburn K , Copsey L , Drzewiecki J , Fundo A , Le Gall A , Gomez S , Javaid H , Lence CF , Martin NM , Mydlowski C , Smith GC Bioorg Med Chem Lett , 18 14 , 12 Jun Cited by: 10 articles PMID: A novel and orally active poly ADP-ribose polymerase inhibitor, KR [2-[methoxycarbonyl 4-methoxyphenyl methylsulfanyl]-1H-benzimidazolecarboxylic acid amide], attenuates injury in in vitro model of cell death and in vivo model of cardiac ischemia.

Oh KS , Lee S , Yi KY , Seo HW , Koo HN , Lee BH J Pharmacol Exp Ther , 1 , 03 Oct Cited by: 15 articles PMID: The chemistry and biology of nitroxide compounds.

Soule BP , Hyodo F , Matsumoto K , Simone NL , Cook JA , Krishna MC , Mitchell JB Free Radic Biol Med , 42 11 , 12 Mar Cited by: articles PMID: PMCID: PMC Review Free full text in Europe PMC. Claim to ORCID Get citation. Follow us News blog Technical blog Twitter YouTube.

About About Europe PMC. Become a funder. Tools Tools overview. ORCID article claiming. Journal list. Grant finder. External links service. Annotations submission service. Developers Developer resources.

Articles RESTful API. Grants RESTful API. API case studies. SOAP web service. Annotations API. OAI service. Bulk downloads. Developers Forum. Help Help using Europe PMC. Search syntax reference. Contact us Helpdesk. Tech blog. Developer forum.

Let us know how we are doing. How are we doing. Europe PMC is a GBC global core biodata resource. Europe PMC is a service of the Europe PMC Funders' Group , in partnership with the European Bioinformatics Institute ; and in cooperation with the National Center for Biotechnology Information at the U.

In the European Union, dietary supplements are regulated by the European Food Safety Authority EFSA. In Canada, dietary supplements are regulated by Health Canada under the Natural Health Products Regulations.

In Australia, dietary supplements are regulated by the Therapeutic Goods Administration TGA. In India, dietary supplements are regulated by the Food Safety and Standards Authority of India FSSAI.

Tags: Aminoacid. Get the most up-to-date information about Ribose-l-cysteine with SGS Digicomply. Stay informed about current regulations, incident monitoring, risk prevention, scientific insights, mentions in the media, and relevant updates.

Smart GPT-like search, customizable dashboard, and comprehensive guides tailored to your specific area, product, and target market. Dietary Supplements Database Ribose-l-cysteine March 7 Where is Ribose-l-cysteine used?

How is Ribose-l-cysteine used in the food industry? Health benefits of Ribose-l-cysteine? What are the dangers of Ribose-l-cysteine?