Category: Health

Gut health and probiotics

Gut health and probiotics

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Gut health and probiotics -

Did you know that all multicellular organisms, including every animal and plant, are covered in a vast array of microorganisms? Microorganisms, also known as microbes, are extremely small microscopic , living organisms, such as bacteria, viruses, yeast, parasites, and more.

They live on our skin, in our body fluids, and throughout our digestive tract in large quantities and varieties. The moment we are born, we encounter countless microorganisms. The number of single-celled organisms on and within you is greater than the number of cells that make up your own body.

This collection of microorganisms, which is unique to each individual, is their microbiota. The collection of the genetic information from all these microorganisms in a specific environment is referred to as the microbiome. Different parts of the body, for example the skin or the intestinal tract, have their own microbiomes and microbiota.

The gut microbiome is exceptionally diverse, with estimates of trillion microorganisms, from , different species! Despite these vast numbers and varied species there is a fine balance. We have co-evolved with these microorganisms — we give them a place to live and food to eat and they help support our overall health.

They produce certain vitamins and short chain fatty acids, interfere with the growth of harmful bacteria, modify the immune system, and improve our health in ways researchers are only beginning to study.

Microbiome: the aggregate of microorganisms, their genetic information, and the conditions of the environment they are in such as the intestinal tract. Microbiota: the microorganisms that inhabit a specific environment such as the intestinal tract. Microorganism: a very small microscopic organism, such as a bacterium, virus, or yeast.

Antimicrobial Antibiotic : a medicine that either inhibits growth of or destroys microorganisms. Probiotic: live microorganism usually bacteria administered with the purpose of improving health.

When we think about the bacteria that colonize, or live in, our intestinal tract, we typically sort them into two categories: beneficial strains of bacteria non-pathogenic , including those in the genera Bifidobacterium and Lactobacillus, and potential disease-causing strains of bacteria pathogenic , including enteropathogenic EPEC and enterohemorrhagic EHEC Escherichia coli, Shigella, and Clostridioides difficile.

Beneficial bacteria keep pathogens in check and offer many health benefits. Disease-causing bacteria release proteins and toxic by-products that can cause inflammation and harmful symptoms such as diarrhea. Some, such as Helicobacter pylori , can be both beneficial in certain quantities and harmful in other quantities.

The balance between beneficial and harmful bacteria is important for maintaining health. The diversity, or different types of microorganisms, of our gut microbiome is critical — greater diversity allows our gut to be resilient and bounce back from any disturbances to the balance.

Several factors can upset this balance, including diet, stress , hygiene, and medications, particularly antibiotics. Dysbiosis occurs when there are shifts in the balance of the microbiota. The beneficial bacteria that populate the digestive tract work in many possible ways, depending on the type of bacteria and other factors, including:.

There are many ways to treat and manage dysbiosis. In cases of bacterial infection, antibiotic treatment might eradicate the offending bacteria. When the problem is ongoing, probiotics and prebiotics can help return balance to the microbiome. In this section, we will explain how we can use these tools to affect the gut.

Canadian laws specify that a probiotic product must contain live microorganisms that research shows to be beneficial, in adequate amounts to confer a health benefit. You will most often find probiotics in the form of supplements, but some foods also contain probiotics not to be confused with fermented foods; see below.

Typically, an approved probiotic will contain a limited variety of beneficial bacteria, sometimes a few strains and sometimes just one. However, the strain s will be a type of bacteria or other microorganism that research studies show to be effective for treating a specific ailment.

The live bacteria populate the gut and help improve the balance in the microbiome, as well as exert specific effects. Bacteria from the Bifidobacterium and Lactobacillus genera can improve health in many ways, but different strains can exert different effects.

For example, research shows that Bifidobacterium infantis Align® can improve abdominal pain, bloating, and gas in those who have irritable bowel syndrome IBS. This probiotic is an effective option for individuals with these specific symptoms, but it might not be helpful for someone with a different set of symptoms or benefit someone with no digestive troubles.

In recent years, there have been many claims made about gut health — especially on social media platforms like TikTok. If you take even just a few minutes to scroll through the GutTok hashtag on the app, you'll see dozens and dozens of videos discussing the health issues a bad gut can cause like increased acne and inflammation, and even more of them touting the benefits of paying special attention to, and healing, your gut like a strong immune system and clear skin.

Probiotics are "beneficial bacteria that keep your gut microbiome healthy," according to Daryl Gioffre , a certified nutritionist and gut health expert. Studies show that probiotics produce substances that activate the immune system and "prevent pathogens from taking hold and creating major disease," according to Harvard Health Publishing.

Probiotics may also lower the number of colds you have in a year, the health hub notes. While probiotics can be found in several foods, Gioffre believes that "supplementation of probiotics has become necessary" because we aren't getting as many probiotics through our diets as our ancestors have in the past.

Here are the most important facts you should know about probiotics and how to get more of them in your system. Harvard Health Publishing also recommends some dairy products like yogurt, especially Greek yogurt, and kefir. When it comes to probiotic supplements, Gioffre suggests taking different types of probiotics and ideally changing the type every three months.

There are two main types of probiotic supplements that Gioffre recommends: spore-based and terrain-based. And the reason is that the digestive system is a harsh terrain.

When you take this probiotic supplement, it's got to go down through the acid in your stomach," he says. Once a spore-based probiotic reaches your gut, its shell opens up and attaches to the gut wall to strengthen the microbiome.

Some probiotic products have been reported to contain microorganisms other than those listed on the label. In some instances, these contaminants may pose serious health risks.

NCCIH-Funded Research NCCIH sponsors a variety of research projects related to probiotics or the microbiome. In addition to the previously mentioned studies on diet-microbiome interactions in the digestive tract, recent topics include: The mechanisms by which probiotics may help to reduce postmenopausal bone loss Engineering probiotics to synthesize natural substances for microbiome-brain research The mechanisms by which certain probiotics may relieve chronic pelvic pain The effects of a specific Bifidobacterium strain on changes in short-chain fatty acid production in the gut that may play a role in antibiotic-associated diarrhea.

This is especially important if you have health problems. Anyone with a serious underlying health condition should be monitored closely while taking probiotics.

Take charge of your health—talk with your health care providers about any complementary health approaches you use. Together, you can make shared, well-informed decisions. For More Information. NCCIH Clearinghouse The NCCIH Clearinghouse provides information on NCCIH and complementary and integrative health approaches, including publications and searches of Federal databases of scientific and medical literature.

Toll-free in the U. gov Email: info nccih. Know the Science NCCIH and the National Institutes of Health NIH provide tools to help you understand the basics and terminology of scientific research so you can make well-informed decisions about your health. Explaining How Research Works NIH Know the Science: How To Make Sense of a Scientific Journal Article Understanding Clinical Studies NIH.

PubMed® A service of the National Library of Medicine, PubMed® contains publication information and in most cases brief summaries of articles from scientific and medical journals. MedlinePlus To provide resources that help answer health questions, MedlinePlus a service of the National Library of Medicine brings together authoritative information from the National Institutes of Health as well as other Government agencies and health-related organizations.

Key References. Bafeta A, Koh M, Riveros C, et al. Harms reporting in randomized controlled trials of interventions aimed at modifying microbiota: a systematic review. Annals of Internal Medicine. Blaabjerg S, Artzi DM, Aabenhus R. Probiotics for the prevention of antibiotic-associated diarrhea in outpatients—a systematic review and meta-analysis.

Butel M-J. Probiotics, gut microbiota and health. Médecine et Maladies Infectieuses. Cohen PA. Probiotic safety—no guarantees. JAMA Internal Medicine. Degnan FH. The US Food and Drug Administration and probiotics: regulatory categorization.

Clinical Infectious Diseases. Didari T, Solki S, Mozaffari S, et al. A systematic review of the safety of probiotics. Expert Opinion on Drug Safety. Dryl R, Szajewska H.

Probiotics for management of infantile colic: a systematic review of randomized controlled trials. Archives of Medical Science.

Fijan S. Microorganisms with claimed probiotic properties: an overview of recent literature. International Journal of Environmental Research and Public Health. Ford AC, Harris LA, Lacy BE, et al. Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome.

Goldenberg JZ, Yap C, Lytvyn L, et al. Probiotics for the prevention of Clostridium difficile -associated diarrhea in adults and children. Cochrane Database of Systematic Reviews. Accessed at www. com on January 23, Guarner F, Khan AG, Garisch J, et al.

World Gastroenterology Organisation Global Guidelines. Probiotics and Prebiotics. October Journal of Clinical Gastroenterology. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis.

Hempel S, Newberry S, Ruelaz A, et al. Safety of Probiotics to Reduce Risk and Prevent or Treat Disease. Rockville, MD: Agency for Healthcare Research and Quality; AHRQ publication no.

Rao SC, Athalye-Jape GK, Deshpande GC, et al. Probiotic supplementation and late-onset sepsis in preterm infants: a meta-analysis. Sanders ME, Akkermans LM, Haller D, et al. Safety assessment of probiotics for human use.

Gut Microbes. Thomas JP, Raine T, Reddy S, et al. Probiotics for the prevention of necrotizing enterocolitis in very low-birth-weight infants: a meta-analysis and systematic review. Acta Paediatrica. Food and Drug Administration.

Warning Regarding Use of Probiotics in Preterm Infants. Issued September 29, attachment on October 2, Zuccotti G, Meneghin F, Aceti A, et al. Probiotics for prevention of atopic diseases in infants: systematic review and meta-analysis. Additional References. Bae J-M. Epidemiology and Health.

Black LI, Clarke TC, Barnes PM, Stussman BJ, Nahin RL. Use of complementary health approaches among children aged years in the United States: National Health Interview Survey, National health statistics reports; no Hyattsville, MD: National Center for Health Statistics.

Cao L, Wang L, Yang L, et al. Long-term effect of early-life supplementation with probiotics on preventing atopic dermatitis: a meta-analysis.

Journal of Dermatological Treatment. Clarke TC, Black LI, Stussman BJ, Barnes PM, Nahin RL. Trends in the use of complementary health approaches among adults: United States, — Dalal R, McGee RG, Riordan SM, et al.

Probiotics for people with hepatic encephalopathy. com on November 15, Dimidi E, Christodoulides S, Fragkos KC, et al. The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition.

Doron S, Snydman DR. Risk and safety of probiotics. Fatheree NY, Liu Y, Taylor CM, et al. Lactobacillus reuteri for infants with colic: a double-blind, placebo-controlled, randomized clinical trial. Journal of Pediatrics. Ghouri YA, Richards DM, Rahimi EF, et al. Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease.

Clinical and Experimental Gastroenterology. Gibson GR, Hutkins R, Sanders ME, et al. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics ISAPP consensus statement on the definition and scope of prebiotics.

Nature Reviews. Goldenberg JZ, Lytvyn L, Steurich J, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. com on November 2, Hao Q, Dong BR, Wu T. Probiotics for preventing acute upper respiratory tract infections.

com on March 6, Hoffmann DE, Fraser CM, Palumbo FB, et al. Probiotics: finding the right regulatory balance. Huang R, Hu J. Positive effect of probiotics on constipation in children: a systematic review and meta-analysis of six randomized controlled trials. Frontiers in Cellular and Infection Microbiology.

Huang R, Ning H, Shen M, et al. Probiotics for the treatment of atopic dermatitis in children: a systematic review and meta-analysis of randomized controlled trials.

Jafarnejad S, Shab-Bidar S, Speakman JR, et al. Nutrition in Clinical Practice. Jørgensen MR, Castiblanco G, Twetman S, et al. Prevention of caries with probiotic bacteria during early childhood.

Promising but inconsistent findings. American Journal of Dentistry. Kechagia M, Basoulis D, Konstantopoulou S, et al. Health benefits of probiotics: a review. ISRN Nutrition. Kelesidis T, Pothoulakis C.

Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders.

Therapeutic Advances in Gastroenterology. Kober M-M, Bowe WP. The effect of probiotics on immune regulation, acne, and photoaging. Lahner E, Bellisario C, Hassan C, et al.

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Current practice is proboitics take daily doses probiotifs probiotics. To start getting the benefits of probiotics, increase your daily consumption of them.

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These Git include:. Ease into xnd your probiotic intake slowly, and pay attention to any side effects anx both positive and negative. Since there are many different strains of probiotics, note how each of them affects you differently. A food and supplement journal would be very helpful for this introductory period.

Recommended daily doses range from 1 billion to 10 billion colony forming units CFUs. Start at 1 CFU and slowly increase while paying attention to how your body responds.

Kefir contains CFUs per cup. Supplements should list their CFUs on the bottle. If fermented foods are new to you, find a friend or highly-rated restaurant to introduce you to them and how to best enjoy. Food sources of probiotics will contain a large variety of strains, but supplements should list each individual type they contain.

The U. Read labels closely and follow storage instructions. Try to pick out a trustworthy brand. If you can, find a doctor who can help you learn more. Reducing the side effects of any of the above issues can improve your quality of life and overall sense of well-being. The benefits of probiotics in your gut go beyond just healthy bowel movements.

A healthy digestive system has been linked to improvements in mental health and immune response. Probiotics are also currently being studied for their benefits to oral health and dermatological health.

By aiding in protein absorption, probiotics can also help your body recover after workout and reduce muscle strain. As concerns rise about antibiotic-resistant infections, probiotics could be powerful protective and healing agents that work seamlessly with our natural body systems.

Probiotics are considered safe for most people. The most commonly reported side effects of probiotics are gas and bloating. If you have severe reactions, including abdominal pain, reduce your daily CFU intake and slowly increase again over time.

Always talk with your doctor before beginning a new health supplement. Before giving probiotic supplements to your child, talk to their pediatrician. Probiotics might not be recommended for people with chronic illness or a weakened immune system. Research indicates a positive association between taking probiotics and healthy digestion in people of all ages.

Healthy digestion also leads to improved mental and oral health, a healthy immune system, and possibly healthier skin. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Probiotics are beneficial in many ways. In men, they can support gut function, urinary health, and even weight loss.

Here are five products you might…. Prebiotics are types of fiber that feed your friendly gut bacteria, leading to all sorts of benefits. Here are 19 healthy foods rich in prebiotics. How long does it take for probiotics to work? Research suggests that probiotics may help support some people's weight loss journeys.

See which probiotics are worth considering in our expert review. Probiotics come in both refrigerated and shelf-stable varieties. This article explains whether you should keep probiotics in the fridge or leave them….

Probiotics are living organisms that may offer health benefits. This article explores if you should take probiotics during pregnancy and if it's safe….

This article examines probiotics' effects on weight loss. Several studies suggest that they can help you lose weight and belly fat. Yogurt with lactobacillus acidophilus can boost heart health and help conditions like diabetes.

Probiotics contain live microorganisms that can support and enhance your healthy gut bacteria. This article reviews whether timing matters when it….

A Quiz for Teens Are You a Workaholic? How Well Do You Sleep? Health Conditions Discover Plan Connect. Medically reviewed by Alan Carter, Pharm. Digestive health How to use Benefits Risks Takeaway Overview. Probiotics and digestion.

How to use probiotics for digestive health. Side effects and risks. How we reviewed this article: Sources. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references.

You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Sep 29, Written By Taylor Norris. Feb 5, Medically Reviewed By Alan Carter, PharmD. Share this article. Read this next. The Best Probiotics for Men. By Jillian Kubala, MS, RD.

The 19 Best Prebiotic Foods You Should Eat. By Arlene Semeco, MS, RD and Erin Kelly. How Long Does It Take for Probiotics to Work? Medically reviewed by Jillian Kubala, MS, RD.

By Cara Rosenbloom, RD. Do Probiotics Need to Be Refrigerated? By Rachael Ajmera, MS, RD. Should You Take Probiotics During Pregnancy? How Probiotics Can Help You Lose Weight and Belly Fat.

: Gut health and probiotics

Probiotics: What You Need To Know

However, there is some research that can help you find a product that meets your needs. Before taking a probiotic, speak with your healthcare team and make sure that there is evidence that the specific strain you wish to take may be beneficial for you.

Also, a trusted group of experts has created an evidence-based guide on probiotic products available in Canada that can support you in your care.

The Alliance for Education on Probiotics AEProbio is an international collaboration of doctors, researchers, and scientists working together to promote the clinical use of probiotics for better health outcomes.

Each year, they conduct an unbiased review of the available scientific evidence on probiotics to update the Clinical Guide to Probiotic Products Available in Canada. Probiotics are products that contain specific strains of bacteria in adequate quantities for which there is evidence showing its efficacy at treating a specific condition.

While the most obvious way to increase the number of beneficial bacteria in your gut is to take a probiotic, you can also feed the good bacteria already in your gut so that they reproduce and populate a higher proportion of your microbiota.

There are certain carbohydrates in our food that we cannot digest, which we call fibre. There are many types of fibre in our food, and helpful bacteria love to chow down on some of them.

These special fibres are prebiotics. The most well known and extensively studied prebiotic is inulin, a type of fructo-oligosaccharides FOS found in plants such as chicory, whole grains, onion, garlic, asparagus, banana, tomatoes, and Jerusalem artichokes, among many others.

Chicory is sold commercially as Benefibre® inulin , although there are other types as well. Galacto-oligosaccharides GOS are plant sugars linked in chains found in breast milk and fermented dairy products, beans, and certain root vegetables. When you eat these foods, the prebiotics stay intact through the stomach and small intestine, then bacteria in the large intestine break the fibres down fermentation and use them as fuel.

This allows the bacteria to reproduce, leading to larger colonies of good bacteria. Make sure to increase your prebiotic intake gradually, since sudden changes in the quantity of fibrous foods you eat can cause bloating, abdominal pain, and other digestive symptoms. Many people mistakenly claim that fermented foods, such as yogurt and sauerkraut, contain probiotics.

As we discussed earlier, probiotics are products that must contain a certain amount and type of live bacteria, based on scientific evidence for certain conditions. Fermented foods contain the microorganisms that initiated the fermentation.

However, the strains of bacteria that these products contain can be variable, and they may or may not still be active by the time they reach your intestinal tract. For these reasons, eating fermented foods is a less reliable way of increasing the populations of beneficial bacteria in the gut than taking probiotic supplements.

If it works with your dietary routine, adding in foods such as yogurt, kefir, sauerkraut, kimchi, and kombucha can be a nice accompaniment to any probiotics you might take to treat digestive diseases and disorders.

There are just as many, if not more, microorganisms living in your digestive tract and on your skin as there are cells in your body! When bacteria eat, they produce waste, and while it might sound gross, these waste products can help us.

For example, when bifidobacteria eat fibre, they produce short-chain fatty acids, which our bodies use to improve immune function and strengthen the intestinal barrier. Some researchers have been looking at these end-point products and considering the possibilities of delivering them directly to the gut.

This might offer a way to bypass the complication of getting living organisms into the gut unharmed, and instead provide the benefits directly.

In addition, this could be a way for individuals who are immunocompromised to obtain the benefits of probiotics. The human microbiome has incredible genomic diversity with almost one hundred fold more genes than in human cells.

You are probably very familiar with antibiotics. While antibiotics kill the bacteria that are causing you to be sick, they also kill helpful bacteria. For instance, yeast infections and Clostridioides difficile C.

difficile , formerly known as Clostridium difficile , infection often occur after taking antibiotics. In some cases, C. difficile infection recurs, and may continue to recur, because the microbiome is imbalanced to the point that it is unable to restore itself. Occasionally, taking probiotics after a course of antibiotics might prevent further damage to the microbiome by repopulating it in a beneficial manner.

However, in many cases it is unnecessary and might make it take longer for the microbiome to recover. Not all antibiotics are created the same, there are types available now and in development that target specific bacteria rather than the entire microbiome.

Remember that probiotics are regulated like food, not drugs. Probiotic manufacturers are not obligated to prove any health benefits of their products.

Probably not. No studies have ever shown that probiotics reduce abdominal pain. In the office, I encourage people to think about a healthy fiber-rich diet instead of probiotics.

Dietary fiber is a prebiotic—it changes which bacteria are present in the gut. Fiber is inexpensive and natural, and by changing your dietary fiber intake you are changing your gut bacteria. Daniel Freedberg, MD , is a gastroenterologist at ColumbiaDoctors and assistant professor of medicine and epidemiology at Columbia University's Vagelos College of Physicians and Surgeons and Mailman School of Public Health.

Can You Make Your Gut Healthier with Probiotics? June 2, What are probiotics? Daniel Freedberg. References Daniel Freedberg, MD , is a gastroenterologist at ColumbiaDoctors and assistant professor of medicine and epidemiology at Columbia University's Vagelos College of Physicians and Surgeons and Mailman School of Public Health.

Journal of Clinical Gastroenterology. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. Hempel S, Newberry S, Ruelaz A, et al. Safety of Probiotics to Reduce Risk and Prevent or Treat Disease.

Rockville, MD: Agency for Healthcare Research and Quality; AHRQ publication no. Rao SC, Athalye-Jape GK, Deshpande GC, et al. Probiotic supplementation and late-onset sepsis in preterm infants: a meta-analysis.

Sanders ME, Akkermans LM, Haller D, et al. Safety assessment of probiotics for human use. Gut Microbes. Thomas JP, Raine T, Reddy S, et al. Probiotics for the prevention of necrotizing enterocolitis in very low-birth-weight infants: a meta-analysis and systematic review.

Acta Paediatrica. Food and Drug Administration. Warning Regarding Use of Probiotics in Preterm Infants. Issued September 29, attachment on October 2, Zuccotti G, Meneghin F, Aceti A, et al.

Probiotics for prevention of atopic diseases in infants: systematic review and meta-analysis. Additional References. Bae J-M. Epidemiology and Health. Black LI, Clarke TC, Barnes PM, Stussman BJ, Nahin RL.

Use of complementary health approaches among children aged years in the United States: National Health Interview Survey, National health statistics reports; no Hyattsville, MD: National Center for Health Statistics.

Cao L, Wang L, Yang L, et al. Long-term effect of early-life supplementation with probiotics on preventing atopic dermatitis: a meta-analysis.

Journal of Dermatological Treatment. Clarke TC, Black LI, Stussman BJ, Barnes PM, Nahin RL. Trends in the use of complementary health approaches among adults: United States, — Dalal R, McGee RG, Riordan SM, et al.

Probiotics for people with hepatic encephalopathy. com on November 15, Dimidi E, Christodoulides S, Fragkos KC, et al.

The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition.

Doron S, Snydman DR. Risk and safety of probiotics. Fatheree NY, Liu Y, Taylor CM, et al. Lactobacillus reuteri for infants with colic: a double-blind, placebo-controlled, randomized clinical trial. Journal of Pediatrics.

Ghouri YA, Richards DM, Rahimi EF, et al. Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease. Clinical and Experimental Gastroenterology.

Gibson GR, Hutkins R, Sanders ME, et al. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics ISAPP consensus statement on the definition and scope of prebiotics. Nature Reviews. Goldenberg JZ, Lytvyn L, Steurich J, et al.

Probiotics for the prevention of pediatric antibiotic-associated diarrhea. com on November 2, Hao Q, Dong BR, Wu T. Probiotics for preventing acute upper respiratory tract infections. com on March 6, Hoffmann DE, Fraser CM, Palumbo FB, et al.

Probiotics: finding the right regulatory balance. Huang R, Hu J. Positive effect of probiotics on constipation in children: a systematic review and meta-analysis of six randomized controlled trials.

Frontiers in Cellular and Infection Microbiology. Huang R, Ning H, Shen M, et al. Probiotics for the treatment of atopic dermatitis in children: a systematic review and meta-analysis of randomized controlled trials. Jafarnejad S, Shab-Bidar S, Speakman JR, et al.

Nutrition in Clinical Practice. Jørgensen MR, Castiblanco G, Twetman S, et al. Prevention of caries with probiotic bacteria during early childhood. Promising but inconsistent findings. American Journal of Dentistry.

Kechagia M, Basoulis D, Konstantopoulou S, et al. Health benefits of probiotics: a review. ISRN Nutrition. Kelesidis T, Pothoulakis C. Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders.

Therapeutic Advances in Gastroenterology. Kober M-M, Bowe WP. The effect of probiotics on immune regulation, acne, and photoaging. Lahner E, Bellisario C, Hassan C, et al. Probiotics in the treatment of diverticular disease.

A systematic review. Journal of Gastrointestinal and Liver Diseases. Lin J, Zhang Y, He C, et al. Probiotics supplementation in children with asthma: a systematic review and meta-analysis.

Journal of Paediatrics and Child Health. Marcason W. Probiotics: where do we stand? Journal of the Academy of Nutrition and Dietetics. Martínez-Martínez MI, Calabuig-Tolsá R, Cauli O.

The effect of probiotics as a treatment for constipation in elderly people: a systematic review. Archives of Gerontology and Geriatrics. Matsubara VH, Bandara HM, Ishikawa KH, et al. The role of probiotic bacteria in managing periodontal disease: a systematic review.

Expert Review of Anti-infective Therapy. Notay M, Foolad N, Vaughn AR, et al. Probiotics, prebiotics, and synbiotics for the treatment and prevention of adult dermatological diseases.

American Journal of Clinical Dermatology. Oelschlaeger TA. Mechanisms of probiotic actions — A review. International Journal of Medical Microbiology. Osborn DA, Sinn JKH. Prebiotics in infants for prevention of allergy. Petschow B, Doré J, Hibberd P, et al. Probiotics, prebiotics, and the host microbiome: the science of translation.

Annals of the New York Academy of Sciences. Reid G. Probiotics: definition, scope and mechanisms of action. Riddle MS, Connor BA, Beeching NJ, et al. Journal of Travel Medicine.

Sanders ME, Guarner F, Guerrant R, et al. An update on the use and investigation of probiotics in health and disease. Schwenger EM, Tejani AM, Loewen PS. Probiotics for preventing urinary tract infections in adults and children. com on November 9, Shanahan F. A commentary on the safety of probiotics.

Gastroenterology Clinics of North America. Steele SR, McCormick J, Melton GB, et al. Practice parameters for the management of Clostridium difficile infection. Diseases of the Colon and Rectum. Lactobacillus reuteri to treat infant colic: a meta-analysis.

Vallabhaneni S, Walker TA, Lockhart SR, et al. Fatal gastrointestinal mucormycosis in a premature infant associated with a contaminated dietary supplement—Connecticut, Morbidity and Mortality Weekly Report.

Venugopalan V, Shriner KA, Wong-Beringer A. Regulatory oversight and safety of probiotic use. Emerging Infectious Diseases. Wei D, Heus P, van de Wetering FT, et al. Probiotics for the prevention or treatment of chemotherapy- or radiotherapy-related diarrhoea in people with cancer. Wojtyniak K, Szajewska H.

Probiotics A Simple Beginner's Guide Breaking down Metabolic health capsules details of prpbiotics surgery. The rise of psychobiotics. Anti-inflammatory remedies for skin conditions, the metabolic activities hsalth your gut flora resemble those of an organ. Diversity and Health Disparities Small Business Research Grant Program SBIR General Award Mechanisms. For more information, see the NCCIH fact sheet on irritable bowel syndrome.
What’s the Connection Between Probiotics and Digestive Health? Sweeten the taste with fresh berries, which are rich in antioxidants and fiber. But there is currently no recommended daily intake for probiotics, according to Harvard Health Publishing. Nutrition in Clinical Practice. The reviewers did not find evidence that any of the probiotics tested in the children were helpful. Adding yogurt or other probiotics—especially the kinds that contain Lactobacillus —during and after a course of antibiotics seems to decrease the chances of subsequently developing these opportunistic infections. Thanks for visiting. Periodic fecal samples revealed higher than typical levels of B.
Recent Posts It's not clear if probiotics that can be bought at Guut and health food stores Anti-inflammatory remedies for skin conditions high-quality products. In Herbal heart health office, I encourage people to probiotcis about a healthy fiber-rich diet instead of probiotics. Probiotic supplements may cause digestive symptoms, which should subside within a few days. Several studies suggest that they can help you lose weight and belly fat. Probiotics are understood to be safe for most people, and there are some general guidelines.
Should you take probiotics? - Harvard Health

Another concern about probiotics is that they're considered dietary supplements, not drugs. As a result, the FDA doesn't monitor the manufacture of probiotics. It's not clear if probiotics that can be bought at pharmacies and health food stores are high-quality products.

It's even possible that some lower-quality products may not even contain the probiotic bacteria that are listed on the label. Plain Greek yogurt is a good source of probiotics.

Sweeten the taste with fresh berries, which are rich in antioxidants and fiber. Supplements aren't the only way to get a daily dose of probiotics.

There are many foods loaded with these cultures of good bacteria. The top sources include. The majority of studies to date have failed to reveal any benefits in individuals who are already healthy. The bacteria seem to help only those people suffering from a few specific intestinal disorders.

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today. This story has played out before, most notably with vitamin supplements, which decades of research have revealed to be completely unnecessary for most adults and, in some cases, dangerous, correlating with higher rates of lung, breast and prostate cancers.

But that has not stopped marketers from pushing another nutritional craze. According to a National Institutes of Health survey, the number of adults in the U. taking probiotics or their cousins, prebiotics typically nondigestible fibers that favor the development of gut bacteria , more than quadrupled between and , from , people to nearly four million.

The popular frenzy surrounding probiotics is fueled in large part by surging scientific and public interest in the human microbiome: the overlapping ecosystems of bacteria and other microorganisms found throughout the body.

The human gastrointestinal system contains about 39 trillion bacteria, according to the latest estimate, most of which reside in the large intestine. In the past 15 years researchers have established that many of these commensal microbes are essential for health.

Collectively, they crowd out harmful microbial invaders, break down fibrous foods into more digestible components and produce vitamins such as K and B The idea that consuming probiotics can boost the ability of already well-functioning native bacteria to promote general health is dubious for a couple of reasons.

Manufacturers of probiotics often select specific bacterial strains for their products because they know how to grow them in large numbers, not because they are adapted to the human gut or known to improve health.

The particular strains of Bifidobacterium or Lactobacillus that are typically found in many yogurts and pills may not be the same kind that can survive the highly acidic environment of the human stomach and from there colonize the gut.

Even if some of the bacteria in a probiotic managed to survive and propagate in the intestine, there would likely be far too few of them to dramatically alter the overall composition of one's internal ecosystem. Whereas the human gut contains tens of trillions of bacteria, there are only between million and a few hundred billion bacteria in a typical serving of yogurt or a microbe-filled pill.

Last year a team of scientists at the University of Copenhagen published a review of seven randomized, placebo-controlled trials the most scientifically rigorous types of studies researchers know how to conduct investigating whether probiotic supplements—including biscuits, milk-based drinks and capsules—change the diversity of bacteria in fecal samples.

Only one study—of 34 healthy volunteers—found a statistically significant change, and there was no indication that it provided a clinical benefit. Despite a growing sense that probiotics do not offer anything of substance to individuals who are already healthy, researchers have documented some benefits for people with certain conditions.

While many small studies have been conducted, there has been no standardized way to study probiotics and their effects, making it difficult to compare the results of different studies. Probiotics are not regulated by the Food and Drug Administration, which means the companies that make probiotics do not need to prove the product contains the ingredients listed on the bottle.

Talk to your health care provider before starting a probiotic. People with very weak immune systems, such as those undergoing chemotherapy, should not take probiotics due to risk of infection.

Your provider or a nutritionist can help identify a probiotic containing the bacteria strain based on the condition you wish to address. Eat a varied diet of protein, grains, fruits and vegetables. Research has shown that a diet containing a variety of different foods is beneficial to our gut microbiome.

Engage in regular physical activity. Studies have shown that a healthy diet and physical activity have separate, positive benefits on our overall wellness. Lisa Hayes, M. Skip to main content. Posted By.

Family Medicine, Prenatal Care, Primary Care.

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Probiotics - Do They Actually Do Anything? Gut health and probiotics

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4 thoughts on “Gut health and probiotics

  1. Ich tue Abbitte, dass sich eingemischt hat... Ich finde mich dieser Frage zurecht. Geben Sie wir werden besprechen.

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