Polyphenols and gut health -
MIRCEN Journal. Anukam KC, Reid G. African traditional fermented foods and probiotics. J Med Food. Rastmanesh R. High polyphenol, low probiotic diet for weight loss because of intestinal microbiota interaction.
Chemico-Biological Interaçtions. Seaman DR. The DeFlame Diet: DeFlame you Diet, Body, and Mind. Wilmington NC : Shadow Panther Press, Not logged in?
ICS Members - Login Here Click Here to Access Your Member Account Click Here to Join the ICS. What About Polyphenols for Gut Health? Previous Changes Made to Required Continuing Education Components.
Next Medicare — When to Collect for Non-Covered Services? About Author. David Seaman, DC, MS, DABCN Dr. Seaman is an adjunct faculty member at Logan College of Chiropractic. He is also a consultant for Anabolic Laboratories, for whom he has designed several nutritional supplements.
He has authored many articles on the topic of diet, inflammation, and pain. His most recent book written for laypeople is entitled The DeFlame Diet. He posts regular DeFlame nutrition updates on Twitter DeflameDoc and DeFlame Nutrition on Facebook.
Related Posts. Search for:. Member Log In Not logged in? Corporate Club Members. Classified Chiropractic Physician - Chicago, IL. IC Chiropractor: Springfield , IL. Chiropractor - Integrated Office. Such protective effects were also attributed to EGCG's modulating effects on the metabolism of sphingolipids.
Colitis is a common gastrointestinal inflammatory disorder and is often studied using animal models. The dextran sulfate sodium DSS -induced colitis murine model is widely used.
Chen et al. and Hou et al. investigated the protective and therapeutic effects of dietary polyphenols on dextran sodium sulfate DSS -induced colitis in mice.
showed that juglone, a natural polyphenol found in walnut trees, alleviated DSS-induced mice colitis by decreasing intestinal inflammation and reducing oxidative stress.
Hou et al. noticed taxifolin, a natural polyphenol be extracted from onions and other vegetables, prevented DSS-induced mice colitis by blunting the NF-κB signaling, enhancing intestinal barrier, and modulating gut microbiota.
Another interesting study performed by Yue et al. applied Irinotecan CPT as the colitis-inducing reagent. The gastrointestinal toxicity caused by CPT strongly limits its anticancer efficacy.
They showed the natural flavonoids from Glycyrrhiza uralensis fisch corrected general intestinal microbial dysbiosis and fecal metabolic disorders in CPTinduced colitis mice and proposed G. uralensis diet as an adjuvant for chemotherapy. Yan et al. contributed an original research article which reported the protective effects of chlorogenic acid a key coffee polyphenol against indomethacin-induced gastrointestinal inflammation and mucosa damage.
Based on cecal microbiota transplantation approaches, they revealed that chlorogenic acid helped maintain intestinal integrity and alleviate inflammatory responses, primarily by inhibiting the growth of Bacteroides and the accumulation of Bacteroides -derived LPS.
Colorectal cancer CRC is one of the most prevalent cancers in the world. In this topic, Ding et al. and Long et al. reviewed the potential of polyphenols to protect against CRC. They provided comprehensive information on understanding the regulatory mechanisms involved, including modulations of the intestinal microbiota, inflammation, as well as cancer cell proliferation and apoptosis-related signaling.
Also, Chen et al. explored the effects of berberine BBR on inhibiting colorectal cancer. These articles are expected to help in the development of future applications of dietary polyphenols in clinical intervention strategies, especially for CRC therapies and prevention.
Gut microbiota dysbiosis is closely related to the development of metabolic disease, such as obesity. Zhao et al. found that monosodium glutamate MSG -induced abdominal obesity, accompanied by gut microbiota dysbiosis, contributes to neuronal damage in the hypothalamus.
Dietary quercetin modulated the gut microbiota, alleviated hypothalamic damage and down-regulated liver RetSat expression, thus ameliorating abdominal obesity. Ding et al. showed that honokiol supplementation improved obesity by regulating the intestinal microbiota and its production of metabolites, and found that sex may be an important factor in determining honokiol activity in obese mice induced by a high-fat diet-induced obese mice.
The gastrointestinal tract is the organ within the body, and its actions play a significant role in shaping the functionality, integrity and composition of the gut microbiota. In the gastrointestinal tract, dietary polyphenols remain largely unabsorbed and accumulate in the large intestine, where they can undergo metabolism by intestinal microbes.
In their article, Ray and Mukherjee describe the fates of dietary polyphenols within the gastrointestinal tract and link this with intestinal microbial ecology, biological activities, and human well-being and disease.
Recent studies suggest that there is a potential link between the development of chronic kidney disease CKD and functional disorders of the gastrointestinal system. A review presented by Bao et al. showed that polyphenols, such as anthocyanin, catechin, chlorogenic acid, and resveratrol, can regulate the intestinal microbiota.
These polyphenols can reduce kidney injury by inhibiting pathogenic bacteria and decreasing host inflammation. Liver diseases represent a major health burden worldwide.
The gut microbiome is often involved in liver diseases and may act via the so-called gut-liver axis. Fu et al. showed that a high-fat diet promotes macrophage-mediated hepatic inflammation and aggravates diethylnitrosamine-induced hepatocarcinogenesis in mice.
A study by He et al. showed Holly Ilex latifolia Thunb. polyphenol extracts could alleviate hepatic damage caused by diquat, a powerful herbicide with strong hepatotoxicity, in challenged piglets.
Another study by Luo et al. Farmed animals remain the main human-consumed sources of protein, and their production requires significant antimicrobial use AMU. Hasted et al. reviewed the immunostimulatory potential of fruits and their extracts in poultry, and showed they had great promise as a replacement for antibiotic applications in poultry production to maintain poultry health and reduce public health risks.
A research article contributed by Cao et al. integrated microbiome and metabolomics approaches to revealed that a polyphenol-rich grape seed extract could be used as an antibiotic substitute in broiler chickens. Another research article presented by Feng et al. explored the effects of polyphenol-rich Ulva prolifera extract on intestinal oxidative stress in weaned piglets and intestinal porcine epithelial cells IPEC-J2 challenged with hydrogen peroxide.
They showed that U. prolifera extract alleviates oxidative stress via Nrf2 signaling, but independent of the AMPK pathway in weaned piglets.
Polyphenols are a group of gealth beneficial Polyphenols and gut health with anti-inflammatory and antioxidant capabilities that exist Polypjenols in a wide Polyphenols and gut health of foods of plant-origin. They are often responsible for the bright helth you see in ajd and Po,yphenols, and actually play a role in protecting Polyphenolls plants that contain them from external Polyphenols and gut health due Polyphenols and gut health the sun, Low-carb diets vs compounds hsalth so on. Among all the potential benefits of polypenol consumption, what intrigues me most is their potential interaction with human gut bacteria. The reality is that across all of the different foods of plant-origin, there are thousands of polyphenol compounds that a human might encounter. These thousands of compounds are part of a smaller number of polyphenol sub-groups which include phenolic acids, flavonoids, lignans and so on. If you pursue variety in your intake of these foods, inevitably you will encounter a wider variety of polyphenol subtypes. According to data published in out of the European Journal Of Clinical Nutrition — there are at least 8 categories of polyphenol containing food groups with certain members of each group representing significantly rich sources. Thermogenic health benefits Geriatrics volume 20Article number: Polyphehols Cite this article. Polyphenols and gut health details. Tut aging, alterations of the intestinal yut ecosystem can occur contributing to immunosenescence, inflamm-aging and impairment of intestinal barrier function increased intestinal permeability; IP. In the context of a diet-microbiota-IP axis in older subjects, food bioactives such as polyphenols may play a beneficial modulatory role. nursing home. The 8-week interventions are separated by an 8-week wash-out period. Three small portions per day of selected polyphenol-rich foods are consumed during intervention in substitution of other comparable products within the C-diet.
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