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Stop Wasting Your Money on These 7 USELESS Supplements! - Dr. Steven GundryPycnogenol benefits -
Maritime pines are known to contain health-promoting plant compounds like vitamins, polyphenols , and other phytonutrients. Many of these are also found in other supplements like grape seed and witch hazel extracts 5 , 7 , 8.
The total amount of compounds in pine bark extract may vary depending on the type of bark used and how it was manufactured 9 , The following is a brief summary of the most notable polyphenol nutrients in pine bark extract and how they may benefit human health:.
These compounds are believed to be what makes pine bark useful as an herbal supplement, giving it the following effects:. Pine bark extract is particularly rich in plant compounds called polyphenols, which are likely responsible for its health-promoting benefits. Test-tube and animal studies from the past few decades have found encouraging results to support the health-promoting benefits of pine bark extract.
Many studies have been conducted on the trademark brand of French maritime pine bark extract known as Pycnogenol. Due to its anti-inflammatory effects, researchers are beginning to investigate it as a possible therapeutic option for the novel coronavirus SARS-CoV-2 , which causes the disease COVID 11 , 12 , Still, rigorous research on the effectiveness of pine bark extract in humans is lacking, and more randomized controlled-trial studies are needed.
Nevertheless, the extract continues to show potential. Here are some of the initial benefits of pine bark extract purported today. Researchers are still investigating how this could benefit conditions like chronic heart disease, diabetes, traumatic brain injuries, and more The apparent ability of pine bark to alleviate inflammation has also led to studies on its potential as a therapeutic treatment for chronic airway inflammation conditions, like asthma and chronic obstructive pulmonary disease COPD 26 , 27 , One study including 76 asthma patients found that taking milligrams of Pycnogenol daily for 6 months, in combination with inhaled corticosteroid medications, significantly improved coughing and wheezing and decreased dependency on the corticosteroids Further, human and animal studies have found that procyanidin-rich pine bark extracts may ease short- and long-term bone and joint inflammation associated with arthritis.
However, larger randomized controlled trials are needed to confirm these findings 34 , 35 , 36 , Because pine bark is both anti-inflammatory and antioxidant-like, it may support a healthy heart and cardiovascular system in a number of ways 38 , 39 , 40 , These include limiting the buildup of fat, reducing oxidative stress and the likelihood of blood clots, and improving venous function 42 , 43 , 44 , One small study including 24 adults with high blood pressure found that taking milligrams Oligopin pine bark daily for 5 weeks improved HDL good cholesterol measures and lowered systolic blood pressure by an average of 6.
Another small study including 23 adults with coronary heart disease associated taking mg of Pycnogenol per day with improved blood flow through the arteries and lower levels of isoprostane — a measure of oxidative stress.
No changes to blood pressure were noted Meta-analysis studies on Pycnogenol and blood pressure have found similar results 50 , 51 , Meanwhile, other studies have found pine bark extract to be less effective at reducing heart disease risk 53 , Pine bark extracts are also being investigated for a multitude of other uses in human, animal, and test-tube studies.
These include:. Pine bark extract is being studied as a therapeutic option to treat many different conditions. Its abilities to reduce inflammation and act as an antioxidant make it a strong candidate to treat chronic diseases. Still, some people may have sensitivities to pine bark, and certain populations — including older adults, pregnant and breastfeeding people, and those who are immunosuppressed.
Because not enough research has been done supporting its safety in these groups, the use of pine bark extract should be avoided. When used as prescribed, pine bark extract is safe and tolerated by most people. Those who are pregnant, older, immunosuppressed, or taking other medications should avoid pine bark extracts.
Commercial pine bark extracts are typically sold as capsules or tablets, though powders and liquid tinctures are available, too. Pycnogenol is one of the most common pine bark extracts on the market. Most commercial supplements suggest a daily dosage.
Many pine bark supplements are sold commercially in liquid, capsule, and powder form. Check with your healthcare provider to determine how much pine bark extract you should take — if any.
Pine bark extract is an herbal supplement rich in healthy polyphenols like procyanidins, catechins, and phenolic acids. These plant compounds appear to have antimicrobial, antioxidant , and anti-inflammatory effects on the human body. As such, pine bark extract shows great potential as a therapeutic herbal supplement.
Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. While you might know pine for its scent, a lot of medicinal claims are being made about its essential oil. Here's what you need to know. Pycnogenol is a popular natural supplement with many uses.
Learn more about what the research says and how to safely use it. When facing an ADHD diagnosis, choosing a treatment plan can be difficult. Learn which herbs may be beneficial for ADHD. Little is known about pycnogenol's interactions with prescription medicines or other herbal supplements.
Some possible drug interactions include the following:. Do keep the following precautions in mind when using pycnogenol:. Dietary supplements are not regulated like prescription medications in the United States. Therefore, some may be safer than others.
When choosing a supplement , consider factors such as third-party testing, potential drug interactions, and other safety concerns.
Talk to a healthcare provider or a registered dietitian nutritionist RD or RDN about supplement quality and safety. Pycnogenol is an antioxidant-rich herbal supplement made from pine bark. It may be helpful for people with OA and could help lower the risk of heart disease and diabetes.
Clinical trials using pycnogenol are very limited, though. Stronger data are needed before it can be recommended for most conditions. Pycnogenol has not been proven safe during pregnancy or breastfeeding or for children under 6.
It also may interact with blood pressure and diabetes medicines, NSAIDs, and some cancer medicines. Pycnogenol has been studied for many conditions, from asthma to traumatic brain injury TBI , but there's not much evidence it works. Some reviews suggest it reduced osteoarthritis pain or prevented heart disease or diabetes, but more clinical trials are needed.
Probably not. In fact, a small study of postmenopausal females showed that pycnogenol promoted hair growth. In small clinical trials, pycnogenol has been shown to protect against ultraviolet UV rays, improve skin elasticity , and reduce melasma overpigmentation of the skin.
Small studies suggest it may be helpful in males with erectile dysfunction who also take antidepressants or have diabetes. A review of clinical trials determined that there isn't enough evidence to know whether pycnogenol improves erectile function or other aspects of sexual health. Robertson NU, Schoonees A, Brand A, et al.
Pine bark Pinus spp. extract for treating chronic disorders. Cochrane Database Syst Rev. Sahebkar A. A systematic review and meta-analysis of the effects of pycnogenol on plasma lipids. J Cardiovasc Pharmacol Ther.
Malekahmadi M, Moradi Moghaddam O, Islam SMS, et al. Evaluation of the effects of pycnogenol French maritime pine bark extract supplementation on inflammatory biomarkers and nutritional and clinical status in traumatic brain injury patients in an intensive care unit: A randomized clinical trial protocol.
Published Feb Verlaet AA, Ceulemans B, Verhelst H, et al. Effect of Pycnogenol® on attention-deficit hyperactivity disorder ADHD : Study protocol for a randomised controlled trial.
Belcaro G, Cornelli U, Luzzi R, et al. Pycnogenol® supplementation improves health risk factors in subjects with metabolic syndrome.
Phytother Res. Simpson T, Kure C, Stough C. Assessing the efficacy and mechanisms of pycnogenol® on cognitive aging from in vitro animal and human studies.
Front Pharmacol. Becit M, Aydin S. An in vitro study on the interactions of Pycnogenol® with Cisplatin in human cervical cancer cells. Turk J Pharm Sci. Ekinci B, Suleyman B, Mammadov R, et al. Beneficial interaction of pycnogenol with indomethacin in rats. Gen Physiol Biophys. Malekahmadi M, Moradi Moghaddam O, Firouzi S, et al.
Effects of pycnogenol on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. Ross SM. Allergic Rhinitis: A Proprietary Extract of Pinus pinaster Aiton Pycnogenol Is Found to Improve the Symptoms Associated With Allergic Rhinitis.
Holist Nurs Pract. Zhao H, Wu J, Wang N, et al. Oral pycnogenol® intake benefits the skin in urban Chinese outdoor workers: A randomized, placebo-controlled, double-blind, and crossover intervention study.
Skin Pharmacol Physiol. Pourmasoumi M, Hadi A, Mohammadi H, Rouhani MH. Effect of pycnogenol supplementation on blood pressure: A systematic review and meta-analysis of clinical trials. Belcaro G, Luzzi R, Dugall M, Ippolito E, Saggino A. Pycnogenol® improves cognitive function, attention, mental performance and specific professional skills in healthy professionals aged J Neurosurg Sci.
Chan V, Wang L, Allman-Farinelli M. Efficacy of Functional Foods, Beverages, and Supplements Claiming to Alleviate Air Travel Symptoms: Systematic Review and Meta-Analysis. Published Mar Vinciguerra G, Belcaro G, Bonanni E, et al. Evaluation of the effects of supplementation with Pycnogenol® on fitness in normal subjects with the Army Physical Fitness Test and in performances of athletes in the minute triathlon.
J Sports Med Phys Fitness. Malekahmadi M, Shadnoush M, Islam SMS, et al. The effect of French maritime pine bark extract supplementation on inflammation, nutritional and clinical status in critically ill patients with traumatic brain injury: A randomized controlled trial.
Lima PB, Dias JAF, Esposito ACC, et al. French maritime pine bark extract pycnogenol in association with triple combination cream for the treatment of facial melasma in women: A double-blind, randomized, placebo-controlled trial.
J Eur Acad Dermatol Venereol. Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Dietary supplements for treating osteoarthritis: A systematic review and meta-analysis. Br J Sports Med. Smetanka A, Stara V, Farsky I, et al.
Pycnogenol supplementation as an adjunct treatment for antidepressant-induced sexual dysfunction. Physiol Int. Belcaro G, Dugall M, Luzzi R, et al. Postpartum varicose veins: Supplementation with pycnogenol or elastic compression-A month follow-up.
Int J Angiol. Toledo RR, Santos MERC, Schnaider TB. Effect of Pycnogenol on the Healing of Venous Ulcers. Ann Vasc Surg.
de Waard AM, Hollander M, Korevaar JC, et al. Selective prevention of cardiometabolic diseases: activities and attitudes of general practitioners across Europe. Eur J Public Health. Rašković A, Bukumirović N, Paut Kusturica M, et al.
Hepatoprotective and antioxidant potential of Pycnogenol® in acetaminophen-induced hepatotoxicity in rats. Cai C, Zeng B, Lin L, et al. An oral French maritime pine bark extract improves hair density in menopausal women: A randomized, placebo-controlled, double blind intervention study.
Health Sci Rep.
Introduction and objectives: In recent Pycnohenol Pycnogenol benefits has been an increasing interest PPycnogenol the use of nutritional supplements to benefit human skin. Molecular evidence Benefits of antioxidant-rich foods such effects, however, Beneefits scarce. Pycnnogenol the present study we investigated whether nutritional Dairy-free energy snacks of women with the standardized pine bark extract Pycnogenol® will improve their cosmetic appearance and relate these effects to expression of corresponding molecular markers of their skin. Materials and methods: For this purpose 20 healthy postmenopausal women were supplemented with Pycnogenol for 12 weeks. Before, during and after supplementation, their skin condition was assessed i by employing non-invasive, biophysical methods including corneometry, cutometry, visioscan and ultrasound analyses and ii by taking biopsies and subsequent PCR for gene expression analyses related to extracellular matrix homeostasis.
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