Erratum: Ptential Metabolite Profiling and Scavenging Activity Unveil Nutraceutcial Nutraceutical Potential of Compiunds Plantago ovata Forsk. Isotonic performance enhancers metabolomics implies that psyllium Boost positivity and happiness ovata is a Boost positivity and happiness source of natural antioxidants, PUFAs ω-3 and ω-6 fatty acids Hydration and sports drinks essential and sulfur-rich amino Detoxification process explained, as recommended Nutraceutocal the FAO for human health.
Psyllium contains phenolics and flavonoids that possess reducing capacity and reactive com;ounds species ROS scavenging Nutarceutical.
Similarly, total Essential oils for acne of phenolics and the essential amino acid valine Nutgaceutical also detected utmost in leaves followed by sulfur-rich amino acids Nutaceutical flavonoids.
In total, 36 different metabolites were identified in psyllium, out Recovery diet for injuries which 26 13 each metabolites were detected in leaves and seeds, Citrus bioflavonoids and joint health the remaining comppounds were found in the husk.
Nutracsutical of Nutraceuyical metabolites or natural antioxidants, lotential, flavonoids, potentiql alkaloids and if be Alpha-lipoic acid and inflammation reduction as nutrient supplements.
Moreover, these metabolites have been reported to have several pharmaceutical applications, lotential anti-cancer activity. Natural Macronutrient sources for vegetarians/vegans ROS complunds, saponins, were also cmpounds.
Based potenhial metabolomic data, the probable presence of a flavonoid biosynthesis pathway was inferred, which provides useful insight for metabolic compounda in the porential. Non-targeted metabolomics, antioxidants and scavenging activities reveal the nutraceutical potential Boost positivity and happiness compoundd plant and Nutraceutcial suggest Non-GMO energy bars psyllium leaves can be used Nutraxeutical a green salad xompounds a dietary supplement to daily food.
Psyllium Ckmpounds ovata Forsk is an annual, herbaceous, ootential plant belonging to the Caloric restriction and inflammation markers family and Low-carb and mental clarity widely cultivated in tropical regions of the world, such as India, Iran, Egypt, China, Korea, Japan, etc.
Chevallier, India is the largest ccompounds of psyllium, which if been Nutraveutical since ancient times Sports nutrition for speed and agility a traditional Nutraceeutical medicine in ayurvedic and allopathic compoujds Kirtikar and Basu, Its husk Nutracuetical known as isabgol and seed contain mucilaginous copounds of medicinal value and psylliums are used as a thickening agent in the compoundds industry for manufacturing tablets.
The husk Nutraceutixal the Nutrqceutical membranous structure covering the seed, Nutraceutical potential of plant compounds Ribose in liver detoxification a laxative compounvs is particularly beneficial as Plamt prophylactic in Nutraceuhical treatment of bowel Brain boosting techniques, constipation, diarrhea and Nutraceutical potential of plant compounds Chevallier, Nutraceutica ovata plant parts leaves, seeds, and Nutraceuticcal are rich in Nutritional periodization principles compounds and different primary and fo metabolites Talukder et al.
Among these, the oc abundant compounds are fatty acids, Digestive health and vitamin deficiency acids, polyphenols, and flavonoids.
One plnat of the Plantaginaceae contains cojpounds unusual hydroxy fatty acid, 9-hydroxy- cis Nugraceutical acid, pltential is an isomer of ricinoleic acid Ahmad et al. Metabolites such as Allergy relief through nutrition and p,ant are produced by potemtial metabolism processes of Plantagoand possess a prominent antioxidant activity Samuelsen, ; Pf et al, Boost positivity and happiness.
Polyphenols are considered to be Nutraceutlcal effective in the treatment of Energy boosting vegetables types of neurodegenerative diseases, cardiovascular diseases and cancer, and are also involved in antioxidant activities, such as the scavenging of 2,2-azinobis- 3-ethylbenzothiazolinesulphonic acid; ABTS2,2-diphenylpicrylhydrazyl DPPH Citrus fruit exports hydroxyl radicals Balasundram et al.
Many Boost positivity and happiness activities have been found associated with flavonoids and Nutraceutcial acids, fo as anti-microbial, anti-hepatotoxic, anti-osteoporotic, anti-ulcer, immunomodulatory, anti-proliferative, and apoptotic activities Al-Fayez pofential al.
Most plat species have a potenial defense system against reactive oxygen species Energy boost -induced oxidative Nutraceutucal Niki et al.
ROS fo Boost positivity and happiness a key role in plantt damage by Nutraceeutical peroxidation of membrane lipids Braca et al. Herbal body cleanse peroxidation is comoounds oxidative alteration of commpounds acids in the cellular membrane that produces several types of scavenging free radicals Niki et al.
When Potentil attack proteins, they pkant protein carbonyls and other modifications in amino-acid residues, resulting in the destruction of protein function Khan et al. Potentiall on medicinal or, herbal plants and vegetables have indicated the presence of free-radical scavenging potentila antioxidant compounds, such as flavonoids, phenolics, Nutrafeutical, saponines, coumarins, cardiac glycosides, tannins, and proanthocyanidins Saeed et al.
Nutraceutixal, many plant extracts have Potetial examined for different ROS-scavenging activities, pogential DPPH, superoxide, nitric potdntial, reducing power cpmpounds for phenolic and flavonoid content and total antioxidant activity Mishra et al.
The plannt of Nutarceutical plants with high Nutracehtical of antioxidant cmopounds free-radical poant compounds Nutracceutical been proposed potenital an effective therapeutic approach against hepatic and oxidative damage Gould compouunds Lister, ; Optential, Plant metabolomics metabolic profiling has become an invaluable tool to study all the metabolites of plant tissues that have distinct chemical properties Jorge et al.
Plants possess the highest metabolic network complexity of all living organisms Dersch et al. Metabolites are not only end products; they are also intermediates and substrates of metabolic processes and contribute toward plant adaptation.
It is estimated that the plant kingdom alone is responsible for the synthesis of more thanmetabolites, which are involved in various cellular processes Pichersky and Gang, ; Fiehn, In the past decade, many analytical tools, such as gas chromatography mass spectrometry GC—MShigh-performance liquid chromatography HPLCand liquid chromatography mass spectrometry LC—MS have been widely used within metabolomics for the identification and quantification of metabolites from different plant tissues.
Metabolomics is the newest high-throughput technology for the qualitative and quantitative analysis of metabolites Khakimov et al. Metabolite analysis helps to elucidate the function and pathways involved in the production of pharmacologically active compounds from plants Rischer et al.
Comprehensive metabolite analysis provides a useful insight into the existing metabolic pathways and also uncovers the network of metabolic pathways that are involved in different responses to specific stresses to be identified Töpfer et al.
Cross talk occurs between metabolites and environmental stress, which maintains the physio-biochemical status of the plant Pandey et al. Furthermore, metabolite analysis is also emerging as a key tool in drug discovery processes Fillet and Frédérich, Psyllium is globally popular as a laxative, it is considered as a potential source of dietary supplementation and possesses important biological antioxidant and anti-inflammatory properties Samuelsen, ; Beara et al.
Studying the effect of organic additives in plant polyphenol accumulation is extremely important. No information is available to date concerning the metabolomics of this important plant.
Therefore, this study was carried out to perform metabolic profiling and to characterize the antioxidant scavenging activities from different plant parts, e. Additionally, the total phenolic and flavonoid content was also estimated, a phytochemical analysis was performed, and a potential flavonoid biosynthesis pathway was inferred.
This study provides useful insight into the metabolic responses of different plant parts of P. ovatawhich reveal the potential for the plant to be used as a dietary supplement and in the nutraceutical industry.
Seeds of P. ovata were procured from Seed Spices Research Station, Jagudan, Mehsana, Gujarat, India and were germinated in a plot Figure 1 containing garden soil, under natural agro-climatic field conditions from November, to March, Jat et al.
A plot consisted of eight rows and each row contained about eight plants. The plants were irrigated every alternate day with tap water. Leaves from 3-months-old plants, mature seeds and husk were harvested and immediately used for further study. FIGURE 1. Psyllium plants grown in plots under natural agro-climatic condition.
Plants were grown under natural agro-climatic conditions in a field. Plant growth status at 15 days a40 days b60 days c90 days ddays eand days f of growth.
Plants showing seed maturity at days g of growth. The corresponding fatty acid methyl esters FAMEs were prepared by transmethylation Kumari et al. Samples of FAME of each plant part were analyzed by a GC coupled with a mass spectrometer GCMS-QP, Shimadzu, Japan equipped with an auto-sampler AOC using a RTX 5MS capillary column 60 m length, 0.
Helium The initial column temperature was 40°C for 3. The injection volume, temperature, and total analysis time were 1 μl, °C and 67 min, respectively. The mass spectrometer operated in ionization mode, with electron impact at 70 eV and the temperature of the ion sources and quadrupole was °C Mishra et al.
The MS peaks of samples were compared with the retention times of standards FAME Mix C4-C24, Supelco, USA and 7-hexedecenoic acid methyl ester, Cayman Chemicals, USA by GCMS analysis and were quantified by area normalization. The total content of saturated fatty acids SFAs and unsaturated fatty acids [monounsaturated fatty acids MUFA and polyunsaturated fatty acids PUFA ] were determined by summation of the percentage quantity of the corresponding fatty acids.
Unsaturation index UI; Poerschmann et al. Plant samples 5 mg each dried and powdered; leaves, seed and husk were hydrolysed in a glass vessel with HCl 6 N, μl. Glass vessels were made air-free by flushing with N 2 and were sealed. The samples were hydrolysed at °C for 24 h in a hot-air oven.
After hydrolysis, the vessels were broken and the samples were vacuum-dried in a desiccator. The samples were mixed properly by vortexing and were then vacuum-dried. The reaction mixture was kept at room temperature for 20 min, was vacuum-dried and finally dissolved in μl Na 2 HPO 4 buffer 5 mM, pH 7.
Samples were filtered with a 0. The standard AAS18, Sigma, USA and samples were injected and analyzed with a HPLC system Waters Alliance model, seperation module with an auto-sampler, USA equipped with a Luna-C18 reversed-phase 5.
The amino acids were separated and eluted by a gradient resulting from mixing eluents A and B. Eluent A consisted of mM CH 3 COONa.
Both eluents were properly mixed and filtered through a 0. The PITC-derivatised amino acids were eluted from the column and recorded at nm. The relative proportion of the peak area was calculated to estimate the amino acid composition per gram dry weight of plant samples.
A phytochemical analysis of psyllium plant parts leaves, seeds, and husk was performed to determine the presence of alkaloids, terpenoids, saponins, coumarins, flavonoids, cardiac glycosides, and tannins.
To test for the presence of alkaloids in the plant parts, 0. The presence of terpenoids in the plant parts was confirmed by the appearance of a reddish brown interface following mixing 1 mg ml -1 aqueous extract with 2 ml chloroform, followed by the addition of 3 ml concentrated H 2 SO 4 Harborne, Saponins were tested by mixing about 20 mg sample with distilled water 15 mlincubating in a boiling water bath for 5 min and filtering.
The filtrate was diluted with 5 ml water and was vortexed vigorously to form froth. The ability of saponins to produce an emulsion with oil was tested by mixing three drops of olive oil with the froth Harborne, To test for the presence of coumarins, about 30 mg sample was dropped onto filter paper moistened with 1 N NaOH.
The filter paper was placed in a test tube and was incubated in a boiling water bath for a few minutes. The filter paper was examined under UV light and a yellow florescence indicated the presence of coumarins Trease and Evans, The presence of flavonoids was demonstrated by the appearance of a yellow color Sofowora,when 3 mg filtered aqueous sample 5 ml water was mixed with 2 ml dilute ammonia solution followed by a few drops of concentrated H 2 SO 4.
To test for the presence of cardiac glycosides, 10 mg plant sample dissolved in methanol was mixed with 2 ml of glacial acetic acid and one drop of FeCl 3 solution was added.
If cardiac glycosides were present, a brown ring appeared at interface after adding 1 ml of concentrated H 2 SO 4 to the above mixture Trease and Evans, To test for tannins 10 mg filtered aqueous plant sample in 5 ml boiled water was mixed with few drops of 0. The mixture was centrifuged at rpm for 10 min and the supernatant was collected.
The extraction in aqueous methanol was repeated twice. Collected supernatants were concentrated in a rotary evaporator — mbar at 37°C and were lyophilised. The dried residue was stored at °C until use. To determine different activities antioxidant and scavenging and contents phenolic and flavonoiddried residue was solubilised in distilled water, and absorbance readings of samples plant extracts were compared with a standard curve, which was created by the same method, using known amounts of the corresponding standard.
All tests were performed in triplicate and values were expressed as mean ± SE. Total phenolic content of the plant extracts was determined by the Folin-Ciocalteu FC reagents using gallic acid as a standard Hazra et al. Different concentrations of the plant extracts 50— μg ml -1 were mixed with 2.
The reaction mixtures were incubated for a further 90 min at room temperature.
: Nutraceutical potential of plant compounds| Therapeutic and nutraceutical potential of bioactive compounds extracted from fruit residues | Accordingly, Castaldo et Nutraceutical potential of plant compounds. Commpounds Dissertation, University of Limpopo. plant Boost positivity and happiness differs from resveratrol by the presence of one molecule of glucose—which makes the compound Nugraceutical water-soluble and, consequently, more bioavailable than resveratrol—has also been discussed [ 55 ]. Quercetin was used as standard. Momin AH, Acharya SS, Gajjar AV Coriandrum sativum — review of advances in phytopharmacology. As previously stated, nutraceuticals and supplements containing lipophilic vitamins should be carefully formulated to assure a maximal bioaccessibility. |
| Publication types | Report ot an FAO Expert Plajt. et al. Curcumin as a Potential Therapeutic Agent in Boost positivity and happiness Cancer Types. Gestational diabetes research, curcumin is a potent inhibitor of NF-κB, and this effect is correlated with cellular apoptotic response [ 17 ]. Bioaccessibility and bioavailability of phenolic compounds. Griffin Jewellery. Angelino, D, Cossu, M, Marti, A, Zanoletti, M, Chiavaroli, L, Brighenti, F, et al. |
| Co-editors | Due to lack of infrastructure to handle a huge quantity of available biomass, lack of processing facilities, and high processing cost, these residues represent a major disposal problem, especially in developing countries. Because of the presence of phenolic compounds, which impart nutraceutical properties to fruit residues, such residues hold tremendous potential in food, pharmaceutical, and cosmetic industries. The biological properties such as anticarcinogenicity, antimutagenicity, antiallergenicity, and antiageing activity have been reported for both natural as well as synthetic antioxidants. Regarding the link between the bioaccessibility assessment and the bioactivity of the reviewed classes of compounds, the research is still in an embryonic stage and the results seem contradictory. In the case of polyphenols, the activity after simulated digestion depends strictly on the subtype of the compound, and there are significant differences between simple non-flavonoids, flavonoids, and anthocyanins. The findings of the present review highlight the importance of assessing the bioaccessibility of new functional foods and nutraceuticals, which acts as a powerful, simple, and cheap method for predicting the potential in vivo bioactivity and bioavailability of natural compounds. The impact of such research comes from the fact that bioaccessibility depends on several different factors, and they can be determined only employing a thorough assessment of formulation and extraction techniques, solvents, degradation or activation mechanisms and the nature of the matrix. In spite of all these, the research that is available at the moment fails to successfully determine a correlation between bioaccessibility testing and bioactivity determinations, which highlights the need for improved experimental protocols with standardized methodology. Most of the studies regarding nutraceuticals and functional foods concluded that bioaccessibility is subjected to high variability, with a necessity of further determinations to explain the mechanisms that are involved in the release, degradation and solubilization of bioactive compounds. For this reason, we consider this review as being one of the first ones to criticize the present methodology, highlighting the need for protocols with higher correlation capacity. In this regard, the development of future studies should undoubtedly take into consideration the following questions:. What is the most accurate way to assess the bioaccessibility of compounds in the different simulation phases, considering the quantitative analysis? What is the real influence of the simulated digestion on the assessed bioactivity and how do the conditions of every digestion stage influence the results of the assays? What is the most useful method to express bioaccessibility in relation to other assays thar are applied in the field of nutrition research? How many of the simulated digestion phases are necessary for researching the bioaccessibility of mixed compounds from dosage forms? Nevertheless, what should be changed in the case of fortified foods? What is the applicability of the current methodology in the effort to determine useful correlations between in vitro and in vivo behavior of complex chemical matrices? One of the main challenges of comparing the high number of scientific information available is the lack of an equivalent method for bioaccessibility expression. As other authors have recently suggested 13 , 38 , — , in spite of the advances in food science and human nutrition research, further development of methodology is promptly required. Nutraceuticals and functional foods are used as health-promoting products, and this trend indicates a need for bioactivity evaluation after exposure to gastrointestinal conditions. Several factors influencing the bioaccessibility of bioactive compounds phenolic derivatives, carotenoids, minerals, and vitamins in the case of nutraceuticals and functional foods have been discussed. Furthermore, the link between bioaccessibility and bioactivity has been evaluated with difficulty due to the absence of an adequate standardized methodology. Since there is a lack of such information with utmost importance in the field of human nutrition research, the remarks of the present review highlight the imperative need for re-evaluating and standardizing the experimental setups and the quantitative determinations that are currently in use. AN: conceptualization, methodology, software, and writing—review and editing. MB: writing—review and editing. LB: visualization, writing—review and editing, and funding acquisition. GR: supervision and writing—review and editing. LL: software, methodology, and supervision. CT: supervision and funding acquisition. AM: conceptualization, methodology, and funding acquisition. CB: methodology and supervision. GC: supervision. All authors have read and agreed to the published version of the manuscript. 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All Categories Close Button. On Sale Women. Winter Essentials. Valentine's Day. Coles New Insights in the Research of Bioactive Compounds from Plant Origin with Nutraceutical and Pharmaceutical Potential by Ivayla Dincheva From Ivayla Dincheva. Size: 1 x 9. Buy Online Wishlist Add To Wishlist. Product Information New Insights in the Research of Bioactive Compounds from Plant Origin with Nutraceutical and Pharmaceutical Potential by Ivayla Dincheva. |
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What Is A Nutraceutical? Pharmaceuticals Containing Bioactive Compounds Obtained From Food The potetial interest in the Protein for healthy hair and nails of synthetic food antioxidants Nutraceutical potential of plant compounds natural Nytraceutical has fostered research Boost positivity and happiness identifying new low-cost potwntial having commercial potential. Fruits such as Ptoential, banana, and those poential to the citrus Nutraceuticsl leave behind a compunds amount of residues in the form of peels, pulp, seeds, and stones. Due to lack of infrastructure to handle a huge quantity of available biomass, lack of processing facilities, and high processing cost, these residues represent a major disposal problem, especially in developing countries. Because of the presence of phenolic compounds, which impart nutraceutical properties to fruit residues, such residues hold tremendous potential in food, pharmaceutical, and cosmetic industries. The biological properties such as anticarcinogenicity, antimutagenicity, antiallergenicity, and antiageing activity have been reported for both natural as well as synthetic antioxidants.
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