Cancer Curcjmin be treated Performance recovery drinks conventional medications. Gene enrichment from Heeart pathway analysis Disewse that both Cyrcumin Curcumin and Heart Disease defense response signaling Strengthening skin barrier mostly activated and altered between the two Cuecumin and that these two signaling pathways were classified and regulated by defense response regulation, indicating the pivotal utilization of curcumin in alleviating an overreactive immune response Figures 5C,Dthe top 10 up-regulated and down-regulated genes enriched in immune response signaling are listed in Table 1. If you choose to use complementary therapies along with your cancer treatment, make sure you tell all your doctors.

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Turmeric for Inflammation: How Much is Enough?

Curcumin and Heart Disease -

Libby P. Inflammatory mechanisms: the molecular basis of inflammation and disease. Nutr Rev ;S­6. Crossref PubMed Cheresh P, Kim SJ, Tulasiram S, et al. Oxidative stress and pulmonary fibrosis. Biochim Biophys Acta ;— Crossref PubMed Frangogiannis NG.

The extracellular matrix in myocardial injury, repair, and remodeling. J Clin Invest ;— Crossref PubMed Xu XY, Meng X, Li S, et al.

Bioactivity, health benefits, and related molecular mechanisms of curcumin: current progress, challenges, and perspectives. Nutrients ;pii:E Crossref PubMed Aggarwal BB, Vijayalekshmi RV, Sung B. Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe.

Clin Cancer Res ;— Crossref PubMed Pahwa R, Jialal I. Chronic inflammation. StatPearls Nojiri S, Daida H. Atherosclerotic cardiovascular risk in Japan. Jpn Clin Med ; Crossref PubMed Frostegård J.

Immunity, atherosclerosis and cardiovascular disease. BMC Med ; Crossref PubMed Zhao TX, Mallat Z. Targeting the immune system in atherosclerosis: JACC state-of-the-art review. J Am Coll Cardiol ;— Crossref PubMed Hansson GK. Inflammation and atherosclerosis: the end of a controversy.

Circulation ;—7. Crossref PubMed Tsuda T. Curcumin as a functional food-derived factor: degradation products, metabolites, bioactivity, and future perspectives. Food Funct ;— Crossref PubMed Rauf A, Imran M, Erdogan-Orhan I, et al.

Health perspective of a bioactive compound curcumin: a review. Trends Food Sci Technol ;— Crossref Liu X, Zhu L, Gao X, et al.

Magnetic molecularly imprinted polymers for spectrophotometric quantification of curcumin in food. Food Chem ;— Crossref PubMed Hewlings SJ, Kalman DS.

Curcumin: a review of its effects on human health. Foods ;6:E Crossref PubMed Ghosh S, Banerjee S, Sil PC. The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update. Food Chem Toxicol ;— Crossref PubMed Willerson JT, Ridker PM.

Inflammation as a cardiovascular risk factor. Circulation ;II Crossref PubMed Cochain C, Zernecke A. Macrophages in vascular inflammation and atherosclerosis. Pflugers Arch ;— Crossref PubMed Welsh P, Grassia G, Botha S, et al.

Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? Br J Pharmacol ;— Crossref PubMed Zhang S, Zou J, Li P et al. Curcumin protects against atherosclerosis in apolipoprotein E-knockout mice by inhibiting toll-like receptor 4 expression.

J Agric Food Chem ;— Crossref PubMed Ghosh SS, Righi S, Krieg R, et al. High fat high cholesterol diet Western diet aggravates atherosclerosis, hyperglycemia and renal failure in nephrectomized LDL receptor knockout mice: role of intestine derived lipopolysaccharide.

PLoS One ;e The inflammatory response in myocardial injury, repair, and remodelling. Nat Rev Cardiol ;— Crossref PubMed Nian M, Lee P, Khaper N, et al. Inflammatory cytokines and postmyocardial infarction remodeling.

Circ Res ;— Crossref PubMed Lv FH, Yin HL, He YQ, et al. Effects of curcumin on the apoptosis of cardiomyocytes and the expression of NF- κ B, PPAR- γ and Bcl-2 in rats with myocardial infarction injury.

Exp Ther Med ;— Crossref PubMed Saeidinia A, Keihanian F, Butler AE, et al. Curcumin in heart failure: A choice for complementary therapy? Pharmacol Res ;—9. PubMed Wang NP, Pang XF. Zhang LH, et al. Attenuation of inflammatory response and reduction in infarct size by postconditioning are associated with downregulation of early growth response 1 during reperfusion in rat heart.

Shock ;— Crossref PubMed Feldman AM, McNamara D. N Engl J Med ;— Crossref PubMed Fung G, Luo H, Qiu Y, et al. Crossref PubMed Fildes JE, Shaw SM, Yonan N, et al.

The immune system and chronic heart failure: is the heart in control? Crossref PubMed Yndestad A, Damås JK, Øie E, et al. Role of inflammation in the progression of heart failure. Curr Cardiol Rep ;— Crossref PubMed Song Y, Ge W, Cai H, et al.

J Cardiovasc Pharmacol Ther ;—9. Crossref PubMed Hernández M, Wicz S, Corral RS. Phytomedicine ;— Crossref PubMed Gao S, Zhou J, Liu N, et al. J Mol Cell Cardiol ;—9. Crossref PubMed Morimoto T, Sunagawa Y, Kawamura T, et al.

The dietary compound curcumin inhibits p histone acetyltransferase activity and prevents heart failure in rats. Curcumin in heart failure: a choice for complementary therapy? Crossref PubMed Barnes PJ, Celli BR. Systemic manifestations and comorbidities of COPD. Eur Respir J ;— Crossref PubMed Su B, Liu T, Fan H, et al.

Inflammatory markers and the risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Crossref PubMed Sin DD, MacNee W. Am J Respir Crit Care Med ;—4. Crossref PubMed Moghaddam SJ, Barta P, Mirabolfathinejad SG, et al.

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice. Carcinogenesis ;— Crossref PubMed Yuan J, Liu R, Ma Y, et al. Curcumin attenuates airway inflammation and airway remolding by inhibiting NF- κ B signaling and COX-2 in cigarette smoke-induced COPD mice. Inflammation ;— Crossref PubMed Funamoto M, Sunagawa Y, Katanasaka Y, et al.

Highly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD. Int J Chron Obstruct Pulmon Dis ;— Crossref PubMed Lee H, Lee IS, Choue R. Obesity, inflammation and diet. Pediatr Gastroenterol Hepatol Nutr ;— Crossref PubMed Schmidt FM, Weschenfelder J, Sander C, et al.

Inflammatory cytokines in general and central obesity and modulating effects of physical activity. Crossref PubMed Kim SH, Després JP, Koh KK. Obesity and cardiovascular disease: friend or foe?

Eur Heart J ;—8. Crossref PubMed Zhao Y, Chen B, Shen J, et al. The beneficial effects of quercetin, curcumin, and resveratrol in obesity. Oxid Med Cell Longev ; Crossref PubMed Pan Y, Zhao D, Yu N, et al. Curcumin improves glycolipid metabolism through regulating peroxisome proliferator activated receptor γ signalling pathway in high-fat diet-induced obese mice and 3T3-L1 adipocytes.

R Soc Open Sci ; Crossref PubMed Ariamoghaddam AR, Ebrahimi-Hosseinzadeh B, Hatamian-Zarmi A, et al. In vivo anti-obesity efficacy of curcumin loaded nanofibers transdermal patches in high-fat diet induced obese rats. Mater Sci Eng C Mater Biol Appl ;— Crossref PubMed Jazayeri-Tehrani SA, Rezayat SM, Mansouri S, et al.

Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease NAFLD : a double-blind randomized placebo-controlled clinical trial.

Nutr Metab Lond ; Crossref PubMed Chuengsamarn S, Rattanamongkolgul S, Phonrat B, et al. Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial.

J Nutr Biochem ;— Crossref PubMed Panahi Y, Khalili N, Sahebi E, et al. Curcuminoids modify lipid profile in type 2 diabetes mellitus: a randomized controlled trial. Complement Ther Med ;—5.

Crossref PubMed Darweesh SKL, Wolters FJ, Ikram MA, et al. Alzheimers Dement ;—9. Crossref PubMed Wyss-Coray T, Rogers J. Inflammation in Alzheimer disease — a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med ;2:a Crossref PubMed Justin BN, Turek M, Hakim AM.

Heart disease as a risk factor for dementia. Clin Epidemiol ;— Crossref PubMed Seo EJ, Fischer N, Efferth T. Pharmacol Res ;— Crossref PubMed Liu ZJ, Li ZH, Liu L, et al. Front Pharmacol ; Crossref PubMed Small GW, Siddarth P, Li Z, et al. Memory and brain amyloid and tau effects of a bioavailable form of curcumin in non-demented adults: a double-blind, placebo-controlled month trial.

Am J Geriatr Psychiatry ;— Crossref PubMed Adibian M, Hodaei H, Nikpayam O, et al. The effects of curcumin supplementation on high-sensitivity C-reactive protein, serum adiponectin, and lipid profile in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.

Phytother Res ;— Crossref PubMed Krishnareddy NT, Thomas JV, Nair S, et al. Biomed Res Int ; Crossref PubMed Mohammadi F, Ghazi-Moradi M, Ghayour-Mobarhan M, et al. The effects of curcumin on serum heat shock protein 27 antibody titers in patients with metabolic syndrome.

J Diet Suppl — Crossref PubMed Vors C, Couillard C, Paradis ME, et al. Supplementation with resveratrol and curcumin does not affect the inflammatory response to a high-fat meal in older adults with abdominal obesity: a randomized, placebo-controlled crossover trial.

J Nutr ;— Effects of curcuminoids plus piperine on glycemic, hepatic and inflammatory biomarkers in patients with type 2 diabetes mellitus: a randomized double-blind placebo-controlled trial. Drug Res Stuttg ;—9.

Crossref PubMed Panahi Y, Alishiri GH, Parvin S, et al. Goel A, Kunnumakkara AB, Aggarwal BB. Biochem Pharmacol. Sahebkar A. Why it is necessary to translate curcumin into clinical practice for the prevention and treatment of metabolic syndrome? Kunnumakkara AB, Bordoloi D, Padmavathi G, Monisha J, Roy NK, Prasad S, Aggarwal BB.

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. Br J Pharmacol. Pulido-Moran M, Moreno-Fernandez J, Ramirez-Tortosa C, Ramirez-Tortosa M. Curcumin and health. Maithilikarpagaselvi N, Sridhar MG, Swaminathan RP, Sripradha R, Badhe B. Curcumin inhibits hyperlipidemia and hepatic fat accumulation in high-fructose-fed male Wistar rats.

Pharm Biol. Li ZY, Ding LL, Li JM, Xu BL, Yang L, Bi KS, Wang ZT. PLoS One. Article PubMed PubMed Central Google Scholar. Shin SK, Ha TY, McGregor RA, Choi MS. Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism.

Mol Nutr Food Res. Usharani P, Mateen AA, Naidu MU, Raju YS, Chandra N. Effect of NCB, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study.

Drugs R D. Soni KB, Kuttan R. Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers. Indian J Physiol Pharmacol. CAS PubMed Google Scholar. Ramirez-Bosca A, Soler A, Carrion MA, Diaz-Alperi J, Bernd A, Quintanilla C, Quintanilla Almagro E, Miquel J.

Implications for atherogenesis prevention. Mech Ageing Dev. Pungcharoenkul K, Thongnopnua P. Effect of different curcuminoid supplement dosages on total in vivo antioxidant capacity and cholesterol levels of healthy human subjects. Phytother Res.

Mohammadi A, Sahebkar A, Iranshahi M, Amini M, Khojasteh R, Ghayour-Mobarhan M, Ferns GA. Effects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trial. Baum L, Cheung SK, Mok VC, Lam LC, Leung VP, Hui E, Ng CC, Chow M, Ho PC, Lam S, et al.

Curcumin effects on blood lipid profile in a 6-month human study. Pharmacol Res. Alwi I, Santoso T, Suyono S, Sutrisna B, Suyatna FD, Kresno SB, Ernie S. The effect of curcumin on lipid level in patients with acute coronary syndrome. Acta Med Indones.

PubMed Google Scholar. A systematic review and meta-analysis of randomized controlled trials investigating the effects of curcumin on blood lipid levels. Clin Nutr.

Rahmani S, Asgary S, Askari G, Keshvari M, Hatamipour M, Feizi A, Sahebkar A. Treatment of non-alcoholic fatty liver disease with Curcumin: a randomized placebo-controlled trial. Rahimi HR, Mohammadpour AH, Dastani M, Jaafari MR, Abnous K, Ghayour Mobarhan M, Kazemi OR. The effect of nano-curcumin on HbA1c, fasting blood glucose, and lipid profile in diabetic subjects: a randomized clinical trial.

Avicenna J Phytomed. PubMed PubMed Central Google Scholar. Maithili Karpaga Selvi N, Sridhar MG, Swaminathan RP, Sripradha R. Efficacy of turmeric as adjuvant therapy in type 2 diabetic patients. Indian J Clin Biochem.

Amin F, Islam N, Anila N, Gilani AH. Clinical efficacy of the co-administration of turmeric and black seeds Kalongi in metabolic syndrome - a double blind randomized controlled trial - TAK-MetS trial.

Complement Ther Med. Yang YS, Su YF, Yang HW, Lee YH, Chou JI, Ueng KC. Lipid-lowering effects of curcumin in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled trial. Chuengsamarn S, Rattanamongkolgul S, Phonrat B, Tungtrongchitr R, Jirawatnotai S.

Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial. J Nutr Biochem. Daily JW, Yang M, Park S. Efficacy of turmeric extracts and Curcumin for alleviating the symptoms of joint arthritis: a systematic review and meta-analysis of randomized clinical trials.

J Med Food. Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions version 5.

The Cochrane Collaboration; Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol. Panahi Y, Khalili N, Hosseini MS, Abbasinazari M, Sahebkar A.

Lipid-modifying effects of adjunctive therapy with curcuminoids-piperine combination in patients with metabolic syndrome: results of a randomized controlled trial.

Sahebkar A, Mohammadi A, Atabati A, Rahiman S, Tavallaie S, Iranshahi M, Akhlaghi S, Ferns GA, Ghayour-Mobarhan M. Curcuminoids modulate pro-oxidant-antioxidant balance but not the immune response to heat shock protein 27 and oxidized LDL in obese individuals.

Panahi Y, Hosseini MS, Khalili N, Naimi E, Soflaei SS, Majeed M, Sahebkar A. Effects of supplementation with curcumin on serum adipokine concentrations: a randomized controlled trial. Panahi Y, Hosseini MS, Khalili N, Naimi E, Simental-Mendia LE, Majeed M, Sahebkar A.

Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: a post-hoc analysis of a randomized controlled trial.

Biomed Pharmacother. Heinl RE, Dhindsa DS, Mahlof EN, Schultz WM, Ricketts JC, Varghese T, Esmaeeli A, Allard-Ratick MP, Millard AJ, Kelli HM, et al. Comprehensive cardiovascular risk reduction and cardiac rehabilitation in diabetes and the metabolic syndrome. Can J Cardiol. Brede S, Serfling G, Klement J, Schmid SM, Lehnert H.

Clinical scenario of the metabolic syndrome. Visc Med. Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of curcumin: problems and promises. Mol Pharm. Murdande SB, Pikal MJ, Shanker RM, Bogner RH. Aqueous solubility of crystalline and amorphous drugs: challenges in measurement.

Pharm Dev Technol. Mirzabeigi P, Mohammadpour AH, Salarifar M, Gholami K, Mojtahedzadeh M, Javadi MR. The effect of Curcumin on some of traditional and non-traditional cardiovascular risk factors: a pilot randomized, double-blind, Placebo-controlled Trial. Iran J Pharm Res. CAS PubMed PubMed Central Google Scholar.

Soare A, Weiss EP, Holloszy JO, Fontana L. Multiple dietary supplements do not affect metabolic and cardio-vascular health. Aging Albany NY.

Article Google Scholar. Neerati P, Devde R, Gangi AK. Evaluation of the effect of curcumin capsules on glyburide therapy in patients with type-2 diabetes mellitus. Jayakumar V, Ahmed SS, Ebenezar KK.

Multivariate analysis and molecular interaction of curcumin with PPARgamma in high fructose diet induced insulin resistance in rats. Nishiyama T, Mae T, Kishida H, Tsukagawa M, Mimaki Y, Kuroda M, Sashida Y, Takahashi K, Kawada T, Nakagawa K, Kitahara M.

Curcuminoids and sesquiterpenoids in turmeric Curcuma Longa L. suppress an increase in blood glucose level in type 2 diabetic KK-ay mice. J Agric Food Chem.

Kang Q, Chen A. Curcumin suppresses expression of low-density lipoprotein LDL receptor, leading to the inhibition of LDL-induced activation of hepatic stellate cells. Are curcuminoids effective C-reactive protein-lowering agents in clinical practice?

Evidence from a meta-analysis. Curcuminoids for the management of hypertriglyceridaemia. Nat Rev Cardiol. Low-density lipoprotein is a potential target for curcumin: novel mechanistic insights. Basic Clin Pharmacol Toxicol.

Sahebkar A, Chew GT, Watts GF. Recent advances in pharmacotherapy for hypertriglyceridemia. Prog Lipid Res. Panahi Y, Ahmadi Y, Teymouri M, Johnston TP, Sahebkar A.

Curcumin as a potential candidate for treating hyperlipidemia: a review of cellular and metabolic mechanisms. J Cell Physiol. Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS, Ko JY, Lin JT, Lin BR, Ming-Shiang W, et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.

Anticancer Res. Download references. This research was supported by the Natural Science Foundation of China grant no. The funding bodies had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. The tables and figures supporting the conclusions of this article are included within the article.

There are also two supplementary tables online. Department of Clinical Nutrition, The Second Affiliated Hospital of Chongqing Medical University, No. You can also search for this author in PubMed Google Scholar. SQ, HR and HDH contributed to the conception and design of the study. SQ, LFH and HDH conducted the literature search and data extraction.

LFH and SQ performed the statistical analyses. SQ, LFH, JJG, SSS, JH and HDH drafted the manuscript. HR and HDH supervised the study. All authors gave final approval. Correspondence to Huaidong Hu. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Open Access This article is distributed under the terms of the Creative Commons Attribution 4. Reprints and permissions. Qin, S. et al. Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials.

Nutr J 16 , 68 Download citation. Received : 10 March Accepted : 05 October Published : 11 October Anyone you share the following link with will be able to read this content:.

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Search all BMC articles Search. Download PDF. Download ePub. Abstract Background Dyslipidemia is an important and common cardiovascular risk factor in the general population. Methods A comprehensive literature search was conducted on PubMed, Embase, Ovid, Medline and Cochrane Library databases to identify randomized controlled trials published as of November that assessed the effect of turmeric and curcumin on blood lipid levels including total cholesterol TC , low-density lipoprotein cholesterol LDL-C , high-density lipoprotein cholesterol HDL-C , and triglycerides TG.

Results The analysis included 7 eligible studies patients. Conclusions Turmeric and curcumin may protect patients at risk of CVD through improving serum lipid levels. Introduction Cardiovascular disease CVD is currently the leading cause of mortality worldwide [ 1 ].

Methods Literature search An online search was carried out for clinical studies published in English language in the following electronic databases: PubMed, Embase, Ovid, Medline and Cochrane Library.

Efficacy measures Primary outcome measures included serum levels of LDL-C, high-density lipoprotein cholesterol HDL-C , TG, and total cholesterol TC. Data extraction Two independent investigators SQ and LFH screened the titles and abstracts of articles initially retrieved on online search of databases, and extracted essential data from eligible full-text articles.

Study quality Risk of bias was assessed independently by 2 reviewers SQ and LFH using the Cochrane Handbook for Systematic Reviews of Interventions [ 30 ].

Statistical analysis The meta-analysis was conducted by using Stata version Results Summary of included studies Of the articles retrieved on initial literature search, a detailed evaluation of 11 full-text articles resulted in the elimination of 2 studies [ 33 , 34 ], due to the use of the same patient groups, and another 2 studies [ 35 , 36 ], owing to incomplete data Fig.

Flow diagram of the literature selection process. Full size image. Table 1 Characteristics of studies included in the meta-analysis Full size table. Table 2 Subgroup analysis of serum total cholesterol TC levels Full size table.

Discussion The epidemic of obesity has contributed to a growing burden of CVD risk factors such as T2DM and MetS [ 37 ] defined as the presence of at least 3 out of the 4 criteria: central obesity, increased blood pressure, high blood sugar levels, and dyslipidemia [ 38 ].

Conclusions Subjects who received turmeric and curcumin experienced a natural cardioprotective effect, with lowering of serum LDL-C and TG levels, as compared to subjects who did not. Abbreviations CETP: Cholesteryl ester transfer protein CI: Confidence interval CVD: Cardiovascular disease HDL-C: High-density lipoprotein cholesterol IR: Insulin resistance LDL-C: Low-density lipoprotein cholesterol MeSH: Medical Subject Heading MetS: Metabolic syndrome PPAR-α: Peroxisome proliferator-activated receptor alpha PPAR-γ: Peroxisome proliferator-activated receptor gamma RCTs: Randomized controlled trials SD: Standard deviation SE: Standard error SMD: Standardized mean difference T2DM: Type 2 diabetes mellitus TC: Total cholesterol TG: Triglycerides.

References World Health Organization: The Top 10 Causes of Death. Article PubMed Google Scholar Musunuru K. Article CAS PubMed PubMed Central Google Scholar Padala S, Thompson PD. Article CAS PubMed Google Scholar Chalasani N. Article CAS PubMed Google Scholar Sniderman AD.

Article CAS PubMed Google Scholar Law M, Rudnicka AR. Article CAS PubMed Google Scholar Goel A, Kunnumakkara AB, Aggarwal BB. Article CAS PubMed Google Scholar Sahebkar A. Article CAS PubMed Google Scholar Kunnumakkara AB, Bordoloi D, Padmavathi G, Monisha J, Roy NK, Prasad S, Aggarwal BB.

Article PubMed Google Scholar Maithilikarpagaselvi N, Sridhar MG, Swaminathan RP, Sripradha R, Badhe B. Article CAS PubMed Google Scholar Li ZY, Ding LL, Li JM, Xu BL, Yang L, Bi KS, Wang ZT. Article PubMed PubMed Central Google Scholar Shin SK, Ha TY, McGregor RA, Choi MS.

Article CAS PubMed Google Scholar Usharani P, Mateen AA, Naidu MU, Raju YS, Chandra N. Article CAS PubMed Google Scholar Soni KB, Kuttan R. CAS PubMed Google Scholar Ramirez-Bosca A, Soler A, Carrion MA, Diaz-Alperi J, Bernd A, Quintanilla C, Quintanilla Almagro E, Miquel J.

Article CAS PubMed Google Scholar Pungcharoenkul K, Thongnopnua P. Article CAS PubMed Google Scholar Mohammadi A, Sahebkar A, Iranshahi M, Amini M, Khojasteh R, Ghayour-Mobarhan M, Ferns GA. Article CAS PubMed Google Scholar Baum L, Cheung SK, Mok VC, Lam LC, Leung VP, Hui E, Ng CC, Chow M, Ho PC, Lam S, et al.

Article CAS PubMed Google Scholar Alwi I, Santoso T, Suyono S, Sutrisna B, Suyatna FD, Kresno SB, Ernie S. PubMed Google Scholar Sahebkar A. Article CAS PubMed Google Scholar Rahmani S, Asgary S, Askari G, Keshvari M, Hatamipour M, Feizi A, Sahebkar A. Article CAS PubMed Google Scholar Rahimi HR, Mohammadpour AH, Dastani M, Jaafari MR, Abnous K, Ghayour Mobarhan M, Kazemi OR.

PubMed PubMed Central Google Scholar Maithili Karpaga Selvi N, Sridhar MG, Swaminathan RP, Sripradha R.

Masafumi Funamoto. Yoichi Sunagawa. Satoshi Shimizu. Yasufumi Katanasaka. Yusuke Miyazaki. Hiromichi Wada. Many high-quality studies Hexrt that turmeric has major benefits Curcumin and Heart Disease your body and brain. Diseqse of these benefits come Memory improvement exercises for adults its main ad ingredient, Curcumn. The spice Strengthening skin barrier as turmeric could be one of the most effective nutritional supplements in existence. Turmeric is the spice that gives curry its yellow color. It has been used in India for thousands of years as both a spice and medicinal herb. Research has shown that turmeric contains compounds with medicinal properties. These compounds are called curcuminoids.