Liver health and cholesterol levels -
A doctor will be able to advise on diet and exercise. A person who has alcohol-related liver disease will usually be advised to stop drinking alcohol. Eating enough protein and carbohydrates as part of a balanced diet can help maintain a healthy weight. Cutting down on fatty foods may reduce the impact of a fatty liver or NAFLD.
Eating plenty of fruits and vegetables, and foods such as bread and potatoes that release energy slowly can help. A diet with plenty of protein is a way of obtaining adequate energy supplies without eating high-cholesterol foods.
Eggs, nuts, chicken breast, and pulses are excellent sources of protein. Eating regularly and snacking between meals can be a healthful way for a person to get enough fuel. A person can help prevent health problems, such as damage to the liver, by reducing high levels of LDL cholesterol.
Saturated fats contain a high level of cholesterol. Many fast foods, cakes, butter, fatty meats such as sausages, full-fat cheese, and cream contain saturated fats. Giving up smoking can also be beneficial.
Making changes to diet and exercise are ways a person can manage high cholesterol. And they will need to maintain these changes to avoid high cholesterol returning.
The liver can repair itself up to a certain point. This means that someone may be able to reduce the damage that has been done if they discover liver disease at an early stage. Losing weight if needed, eating a healthful diet, exercising, and cutting down on alcohol can help to reduce the impact of liver disease.
High cholesterol does not usually cause obvious symptoms. In this article, we will look at the effects of cholesterol on the body and how to lower the…. Most types of cheese are high in cholesterol and saturated fat.
Studies provide conflicting information about the relationship between cheese and…. In this article, learn about the different kinds of cholesterol, what different factors affect cholesterol levels, and when to contact a doctor.
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Medical News Today. Health Conditions Health Products Discover Tools Connect. How are liver function and cholesterol production linked?
Medically reviewed by Saurabh Sethi, M. Healthy levels Effects Diagnosis Treatment Diet Prevention Takeaway Most cholesterol in the body is made in the liver and is necessary for good health.
What are healthy levels of cholesterol? Effects of high cholesterol. Diagnosing high cholesterol. What are the treatment options? How we reviewed this article: Sources.
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Citation: Malhotra P, Gill RK, Saksena S and Alrefai WA Disturbances in Cholesterol Homeostasis and Non-alcoholic Fatty Liver Diseases.
Received: 02 June ; Accepted: 13 July ; Published: 02 September Copyright © Malhotra, Gill, Saksena and Alrefai. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY.
The use, distribution or reproduction in other forums is permitted, provided the original author s and the copyright owner s are credited and that the original publication in this journal is cited, in accordance with accepted academic practice.
No use, distribution or reproduction is permitted which does not comply with these terms. Alrefai, walrefai uic. Mechanisms of Chronic Liver Diseases: Identifying New Therapeutic Targets.
Export citation EndNote Reference Manager Simple TEXT file BibTex. Check for updates. MINI REVIEW article. Disturbances in Cholesterol Homeostasis and Non-alcoholic Fatty Liver Diseases Pooja Malhotra 1 Ravinder K. Gill 1 Seema Saksena 1,2 Waddah A. Introduction Non-alcoholic fatty liver disease NAFLD is a common chronic hepatic disorder associated with obesity and metabolic syndrome 1 , 2.
Cholesterol Homeostasis Maintaining cholesterol pool in the body is achieved by balancing between input and output pathways of cholesterol metabolism 7. Table 1. c PubMed Abstract CrossRef Full Text Google Scholar.
M PubMed Abstract CrossRef Full Text Google Scholar. x PubMed Abstract CrossRef Full Text Google Scholar. aaf PubMed Abstract CrossRef Full Text Google Scholar. Keywords: NPC1L1, ezetimibe, statins, bile acids, fatty liver Citation: Malhotra P, Gill RK, Saksena S and Alrefai WA Disturbances in Cholesterol Homeostasis and Non-alcoholic Fatty Liver Diseases.
Liver function and cholesterol are much more Raspberry ketones for fat burning linked than we pay attention to. People qnd high blood cholesterol are more likely leveld develop Livsr Non-Alcoholic Fatty Liver Diseaseand liver problems increase the likelihood of high lsvels A virtuous cycle Liver health and cholesterol levels cholesterl need to break. Level has amd cholesterol in their Hydration and hydration, but high levels can lead to a build-up of fat in your liver and damage the liver. So, What is cholesterol? Cholesterol is a fatty substance that is vital for the proper functioning of the body. The liver plays a key role in regulating cholesterol levels in the body, firstly by making cholesterol to be delivered to cells that need it around the body, and secondly by removing cholesterol by converting it to bile salts so the body can get rid of it in bile and faeces. If your liver is damaged or is poorly functioning, the production of bile may be reduced, which can result in increased cholesterol levels.Cholesterol is a type of fat. After Liver health and cholesterol levels body produces cholesterol, Reliable electrical utilization liver packages it and it flows through your blood. Cholesterol helps send Reliable electrical utilization signals Livet over the body.
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Romit Healtb, MD hsalth, explains how our bodies produce cholesterol Liver health and cholesterol levels how much we actually need. Bhattacharya is a Mass General Livsr cardiologist and cholfsterol associate levela of the Cardiac Lifestyle Program at Massachusetts General Hospital.
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Your diet gives your liver Liver health and cholesterol levels necessary ingredients Long-term weight loss make cholesterol.
Traditional medicine practitioners circulates Curb hunger and reduce calorie intake your blood with the help of proteins, creating a haelth called a lipoprotein.
Znd blood Levwls 2 main types cholesterl these cholesterol molecules:. However, Dr. Bhattacharya emphasizes that LDL Fitness for busy professionals not ehalth inherently bad molecule.
The amount of cholesterol leevls your liver makes heath on how many Pre-game meal guidelines for performance you give cho,esterol. Even choelsterol you have more than you need, your liver keeps producing cholsterol if it can.
Cholessterol your body produces cholesterol, the amount of HDL compared to LDL matters. A healthy diet and lifestyle decrease LDL cholesterol, in addition to decreasing your total cholesterol.
As a result, the ratio of HDL to LDL improves. When you eat sugar, your body releases a hormone called insulin. Insulin controls many processes in the body, but importantly, it signals to your liver to make more cholesterol. In fact, people with genetic mutations that cause them to have extremely low levels of blood cholesterol—even in the single digits—show no significant side effects.
He notes that babies potentially need the most cholesterol as they grow and develop. Yet babies are completely healthy having half as much cholesterol as the average American adult. When you have lots of cholesterol in your body, it builds up wherever it can.
Over time, it accumulates in the artery walls, leading to heart attack or stroke. You can do a few key things to reduce your cholesterol and prevent disease, including:. Skip to cookie consent Skip to main content Skip to alerts Skip to pause carousel. About Us Newsroom How Is Cholesterol Produced?
More alert details. How Is Cholesterol Produced? Contributor: Romit Bhattacharya, MD. Apr 7, share on facebook. How does the liver make cholesterol? Excess LDL can deposit fat and cholesterol in your artery walls.
Very-low-density lipoproteins VLDL are similar to LDL, but mainly carry triglycerides a type of fat. It brings the excess back to your liver to ultimately get flushed out of your body. Your blood has 2 main types of these cholesterol molecules: Low-density lipoproteins LDL : LDL cholesterol carries molecules from one part of your body to another.
High-density lipoproteins HDL : HDL cholesterol soaks up extra cholesterol and fat throughout your body like a sponge. No cholesterol level in the blood has ever shown to be too low for humans.
Romit Bhattacharya, MD Cardiologist Mass General Brigham. How much cholesterol is produced by the body?
How much cholesterol do we need? What happens when you have too much cholesterol? You can do a few key things to reduce your cholesterol and prevent disease, including: Improve your cholesterol levels with a healthy diet of foods that lower cholesterol.
Look for foods that are low in sugar, fat, and cholesterol. Avoid the worst foods for high cholesterol. These are foods with high saturated fat content, including red meat, full-fat dairy, baked goods, fried foods, tropical oils, and butter.
Lead a healthy lifestyle that includes consistent movement and exercise. Take medications as recommended by your health care provider to block cholesterol production. Find a cardiologist near you. Romit Bhattacharya, MD.
: Liver health and cholesterol levels| MINI REVIEW article | However, in macrophages from the original high-cholesterol group, genes that lead to scarring remained active even after the switch. This key result suggests that regularly eating too much cholesterol can cause long-term, difficult-to-reverse changes in macrophages, sabotaging their healing action so they continue to cause liver damage. The high-fat, high-sugar diet given to mice in the study has unfortunate similarities to the typical Western diet in humans. After all, a certain amount of fat, including cholesterol, is needed for our bodies to function properly. Change your diet and exercise more, so you can burn that fat in the liver, because it can cause damage in the long term. Other co-authors of the study are Matthew Salomon, Angela Hsu, Gary Kanel and Lucy Golden-Mason, all of USC. The study was supported by the National Institutes of Health DK, DK and the USC Research Center for Liver Disease P30DK Skip to Content. Journalist on Deadline? In This Section Newsroom Press Releases Campus News Research in 60 Seconds Media Mentions For Journalists Events Calendar. Press Release. High cholesterol leads to long-term liver scarring and immune cell dysfunction in lab study. Wayne Lewis September 16, Image of fatty liver disease showing triglyceride fat accumulated inside liver cells. Image iStock. What this suggests for your diet: everything in balance The high-fat, high-sugar diet given to mice in the study has unfortunate similarities to the typical Western diet in humans. Rather, moderation is key. Related posts: Familial Hypercholesterolemia Is In The Genes: Do You Have It? Understanding Your Cholesterol Numbers Spot Early Signs Key Warnings for Possible FH What Is Heterozygous Familial Hypercholesterolemia? Virgil September 27, I read a lot of interesting content here. Probably you spend a lot of time writing, i know how to save you a lot of work, there is an online tool that creates readable, SEO friendly articles in seconds, just type in google — laranitas free content source Reply. Name required. Email will not be published required. Join us in the fight. Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe Åland Islands Country. Industry Member. Familial Hypercholesterolemia FH. Homozygous FH HoFH. High Lipoprotein a. |
| What is the Correlation Between Cholesterol and Liver Diseases? | Vitamin B12 is found to play a role in adipocyte metabolism. Thus its deficiency could increase the levels of homocysteine along with raising the total cholesterol levels in the body. Niacin, or Vitamin B, is found to fight high cholesterol as it eliminates the bad cholesterol and increases the levels of good cholesterol in the body. Yes, to some extent, physical activities such as walking, jogging, swimming, etc. Dr Aman Priya Khanna is a well-known General Surgeon, Proctologist and Bariatric Surgeon currently associated with HealthFort Clinic, Health First Multispecialty Clinic in Delhi. He has 12 years of experience in General Surgery and worke She is a high-impact healthcare management and medical content professional with enriching work experience in Parexel, HexaHealth Technologies, Apollo Munich, Credihealth and Fortis Hospital. Armed with deep and c View More. Select Your City ×. Book Free Appointment. Medically Reviewed by Dr. Aman Priya Khanna Written by Dr Sania Datta , last updated on 19 May Fatty liver disease is a hepatic abnormality that curbs the liver's ability to process the ingested material and generate unwanted waste for excretion. In this condition, there is an excess accumulation of fat in the liver. Numerous factors such as unhealthy lifestyle or habits play a major role and are responsible for loading the liver with destructive fats. If explained with an example, eating too much fat, particularly food with high cholesterol can harm the liver along with affecting the heart health. However, it is equally important to acknowledge the relationship between fatty liver and cholesterol. This is because high cholesterol levels not only affect cardiac activities but also damage the liver greatly, i. a condition known as fatty liver. Read below to know more about it. Cholesterol levels are produced as well as regulated by the liver with the help of two mechanisms. For example, when the levels are low, the liver produces cholesterol and delivers it to other body parts. And when the levels are higher than the acceptable limit, the liver attempts to eliminate it by converting excess cholesterol into bile salts. The body then excretes the bile salts in excreta and bile. High cholesterol levels in the blood can be a potential indicator of abnormal liver functioning, indicating the presence of fatty liver. This is because bile production is hampered in fatty liver, and cholesterol levels are raised at the same time. If this condition prevails for longer, there are higher chances of an individual suffering from end-stage liver problems, such as Liver Cirrhosis. Book Appointment for Name. Adversities of High Cholesterol Excess cholesterol in the bloodstream signals that the body is soon or is already in the process of undergoing devastation. Hyperlipidemia is a condition in which the blood cholesterol profile is raised. During Chronic Cholestatic Liver Disease, hyperlipidemia comes into the picture. This liver disease is marked by high HDL and comparatively low LDL levels. Coronary Heart Disease is another health complication caused by high cholesterol levels in the blood. Here, the Low-Density Lipoproteins, or LDL, exceed HDL levels. The LDL increasingly settles in the walls of arteries, leading to the formation of plaques hardening of arteries due to fat accumulation. This eventually results in the condition known as arteriosclerosis. Due to this, the arteries become narrow, and the flow of blood through them decreases, concluding in partial or total blockages in the arteries. Cholesterol ingested in the form of food undoubtedly goes to the liver. When dietary cholesterol levels are higher than the permissible limit, the liver loses its ability to process fat and convert it into bile acids. As a result, the excess fat or cholesterol begins to deposit in the liver, resulting in the condition known as fatty liver disease. When not detected or diagnosed on time, the condition could turn fatal, developing into a severe disease called nonalcoholic fatty steatohepatitis. Also, fatty liver cholesterol levels can make the liver face terrible episodes such as cirrhosis scarring of the liver , hepatic cancer, or even liver failure at the end stage. Stages of the fatty liver affected by cholesterol Changes in the structure and functions mark fatty liver cholesterol levels. Given below is a series of fatty liver progression: The first stage , called simple steatosis, is normal, where the damage level is the least. Here, the fat accumulated in the liver cells is harmless and thus does not exhibit any sign of abnormality. Also, if not bothered, it can go unnoticed, provided an individual gets tested for it due to other noticeable complications in the body. The second stage is known as steatohepatitis. This can be considered a more severe one as it is the marked grade of fatty liver progression. The liver undergoes structural change here, showing inflammation due to more fat accumulation. In the third stage , liver fibrosis is usually seen. The presence of inflammation accompanied by fibrosis contributes to the scarring or damaging of tissues on the surface of the liver. Along with the tissues, blood vessels in proximity suffer similar damage. However, the liver still functions at this stage and does not exhibit abnormality. The last or most severe stage occurs after years of liver suffering from inflammation and fibrosis. Cirrhosis is the end stage of fatty liver, where the liver has scars with a lumpy appearance. Ways of stopping cholesterol from liver damage Fatty liver and cholesterol are linked to one another. Read below to learn how to stop the liver from producing cholesterol. Weight Loss Making attempts at weight loss can help lower the cholesterol levels in the body. It's better to have more focus on reducing HDL cholesterol as it's the one that tends to accumulate in the liver cells. Physical activities such as cardiovascular exercises, namely cycling, jogging, swimming, etc. Follow a good diet Healthy food or a balanced diet can help reduce cholesterol levels. Eating more fibre and good carbohydrates, i. replacing regular bread with multigrain slices or switching to natural fruits rather than consuming processed sugary drinks. Also, it is crucial to limit the consumption of cholesterol, i. avoiding cheese, red meat, or any other product which consists of high quantities of saturated fatty acids. Adopt a Healthy Lifestyle Ending to all the bad habits can also stop the liver from producing cholesterol. Smoking and drinking are the two enemies that contribute to disturbing most functions of the body and can equally affect the body's lipid mechanism too. Hence, limiting alcohol intake and distancing oneself from smoking can sufficiently manage cholesterol levels. Summary Most of the time, fatty liver disease does not exhibit more symptoms until the severity level is high; however, a routine check-up is always an ideal backup plan to avoid such undesired health crises. Frequently Asked Questions Will lowering cholesterol help fatty liver? Book Appointment Book Appointment. How to stop the liver from producing cholesterol? What is the function of cholesterol in the body? Cholesterol kuh-LES-teh-rawl helps build cell membranes and is used to make hormones, like estrogen and testosterone, and vitamin D. Most parents probably don't think about what cholesterol means for their kids. But heart disease has its roots in childhood. So high levels of cholesterol in children can increase their chances of heart disease and strokes as adults. The liver makes all the cholesterol that the body needs. But cholesterol also comes from some of the foods we eat. Foods that are high in saturated fat and trans fat also can increase the liver's production of cholesterol. Cholesterol in the blood doesn't move through the body on its own. It combines with proteins to travel through the bloodstream. Cholesterol and protein traveling together are called lipoproteins lie-poh-PRO-teenz. Low-density lipoprotein LDL and high-density lipoprotein HDL are the lipoproteines that most of us have heard about. Low-density lipoproteins, or "bad cholesterol," can build up on the walls of the arteries. Cholesterol and other substances in the blood form plaque. Plaque buildup can make blood vessels become stiffer, narrower, or blocked. Plaque makes it easier for blood clots to form. A blood clot can block a narrowed artery and cause a heart attack or stroke. Atherosclerosis ah-theh-roe-skleh-ROE-siss , or hardening of the arteries, also leads to decreased blood flow to vital organs, including the brain, intestines, and kidneys. High-density lipoproteins, or "good cholesterol," carry cholesterol away from the arteries and back to the liver. In the liver, cholesterol is broken down and removed from the body. People who are physically active, eat healthy foods, don't have a family history of high cholesterol or heart disease, and aren't overweight are less likely to have high cholesterol. All kids should have their cholesterol checked when they're between 9 and 11 years old and again when they're between 17 and Your doctor can order a blood test to check your child's cholesterol. Your child may have to fast nothing to eat or drink, except water, for 12 hours before the test. According to the National Cholesterol Education Program NCEP guidelines, the ranges of total and LDL cholesterol for kids and teens 2—18 years old are:. The goals are to:. |
| More on this topic for: | A biopsy will remove a tiny piece of liver tissue to test for disease. A heart-healthy eating plan limits the amount of saturated and trans fats that you eat. If blood flow to the heart is restricted, it can increase the risk for coronary heart disease. These are foods with high saturated fat content, including red meat, full-fat dairy, baked goods, fried foods, tropical oils, and butter. The following conditions can affect the liver in a way that causes cholesterol levels to be abnormal. They can become narrower, as a result, which restricts the supply of blood and oxygen to the organs. |
| What are LDL and HDL cholesterol? | Nonalcoholic steatohepatitis is associated with altered hepatic microRNA expression. Intestinal absorption of bile acids in health and disease. The Complete Guide to Understanding Fatty Liver and NASH. Hence, with a few simple steps or fundamental lifestyle changes, an individual can reach the ideal cholesterol levels and eventually combat fatty liver. It will be important to investigate a possible difference in the efficiency of cholesterol absorption in patients with NASH as compared to those with NAFLD. Two important types are high-density lipoproteins HDL and low-density lipoproteins LDL. |
| The Liver and Cholesterol: What You Should Know | Cholesterol, Chemistry, Biochemistry And Pathology. High-density lipoproteins HDL : HDL cholesterol soaks up extra cholesterol and fat throughout your body like a sponge. After the age of menopause, women's LDL levels tend to rise. de Souza, L. For example, rural people are less aware of dyslipidemia and get limited health facilities compared to urban people. Share sensitive information only on official, secure websites. |
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Understand Your CHOLESTEROL PANEL \u0026 Metabolic Health Tests - The ULTIMATE Guide - Dr. Robert Lustig Most Citrus oil for promoting sleep in the body is made in Liver health and cholesterol levels liver Reliable electrical utilization is necessary xholesterol good cholesyerol. But some choletserol of cholesterol can cause several health levesl, including damage to the liver. Cholesterol is a fatty molecule that is found in some foods as well as being made in the liver. There are two primary forms of cholesterol, one that is useful to the body, and one that can build up and cause health problems. High-density lipoprotein HDL and low-density lipoprotein LDL are the two main types of cholesterol.Liver health and cholesterol levels -
The most common form of liver malfunction is nonalcoholic fatty liver disease NAFLD. It affects approximately one-quarter of the population. NAFLD is associated with dyslipidemia , abnormal levels of cholesterol and similar compounds in the blood.
NAFLD also can trigger lipodystrophy , irregularities in how the body distributes fat. NAFLD covers a spectrum of conditions. Within NAFLD is the more serious non-alcoholic steatohepatitis NASH.
A diagnosis of NASH often leads to cirrhosis, liver failure, and hepatocellular carcinoma. Cirrhosis can cause scarring and prevent the liver from carrying out basic metabolic functions.
The condition is a reaction to long-term injury to the organ. The injury can include inflammation from a disease such a hepatitis C. After hepatitis C, long-term alcohol abuse is the most common cause of cirrhosis in the United States. Another significant cause of liver problems is damage from drugs.
That makes it susceptible to injury from prescription, over-the-counter, or recreational drugs. Acute hepatitis. Chronic hepatitis. After discontinuing the drug, liver damage is typically not severe and often subsides. In rare cases, the damage can be severe or permanent.
Read more: Fatty liver ». High levels of LDL cholesterol increase the risk of fatty deposits on vessels that bring blood to the heart.
Too-low levels of HDL cholesterol suggest the body may not be able to clear plaques and other fatty deposits from the body. Both conditions create a risk for heart disease and heart attack.
Liver damage can progress for months or years with no symptoms. By the time symptoms appear, liver damage often is extensive. Some symptoms warrant a visit to the doctor.
These include:. A doctor may be able to diagnose liver problems by observing your symptoms and completing a medical history. You may also undergo tests of your liver function.
These tests include. Liver enzyme test : Common enzymes in this panel are alanine transaminase, aspartate transaminase, alkaline phosphatase, and gamma-glutamyl transpeptidase. High levels of any of these enzymes may indicate damage. Liver protein test : Low levels of the proteins globulin and albumin can show a loss of liver function.
Prothrombin is a liver protein needed for clotting. A common test measures how long it takes for your blood to clot. Slow clotting time can mean a lack of prothrombin and liver damage. Bilirubin test : The blood transports bilirubin to the liver and gallbladder. Blood in the urine or excess bilirubin in the blood can show liver damage.
Single lipoprotein panel : The panel tests blood cholesterol and tryglycerides together. Blood typically is drawn after fasting. The researchers fed mice a high-fat, high-sugar diet shown to cause a form of advanced fatty liver disease similar to human illness.
The mice were split into three groups that received different amounts of cholesterol in their food for 20 weeks — midlife for the animals. The low-cholesterol group received one-quarter the cholesterol compared to medium; the high-cholesterol group received 25 times more than the low-cholesterol group.
After 20 weeks, the livers of mice from all three groups showed accumulation of fat, a benign feature of fatty liver disease, but the high-cholesterol group had more advanced disease, with increased inflammation and scar tissue.
For the following 10 weeks, mice from all three groups received low cholesterol as part of a diet that remained high in fat and sugar. At the end of that time, that change in diet had reversed inflammation in the original high-cholesterol mice, but had not reduced scar tissue.
This finding shows that damage caused by high cholesterol can be hard to undo. There are multiple roles for macrophages. They can spur inflammation to fight off invading bugs; quell inflammation when danger has passed; communicate with other immune cells; and even help with healing.
The researchers used RNA sequencing to contrast which genes were activated in liver macrophages from mice in the study with gene expression in normal macrophages. However, in macrophages from the original high-cholesterol group, genes that lead to scarring remained active even after the switch.
You can work to prevent high cholesterol and triglycerides by reducing risk factors that are in your control. You can make healthy lifestyle decisions, such as choosing healthier foods with less saturated fat and quitting smoking.
If you already have high LDL cholesterol and triglyceride levels, your health care team may recommend medicines that treat high cholesterol and triglyceride levels and lifestyle changes to lower your risk for heart disease and stroke.
If you already have low HDL cholesterol levels, talk with your doctor about lifestyle changes that may help raise your levels. Getting your cholesterol checked regularly is an important way of to stay in control of your cholesterol health.
Work with your health care team on how often you should get screened. Skip directly to site content Skip directly to search. Español Other Languages. LDL and HDL Cholesterol and Triglycerides.
Cholesterol is a type Pre-game meal guidelines for performance fat. Cholesterrol your body produces Balanced diet advice, Reliable electrical utilization liver packages it cholesteroll it flows through your blood. Cholesterol helps send important signals all over the body. It wraps around other molecules to carry them through the bloodstream from one place to another. But when you have too much cholesterol, it can build up in your arteries and lead to serious health problems.
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