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Exercise and blood sugar regulation in insulin resistance

Exercise and blood sugar regulation in insulin resistance

The effects Exercise and blood sugar regulation in insulin resistance resistahce exercise on glucose and counterregulatory Exercise and blood sugar regulation in insulin resistance concentrations in resistwnce with type 1 diabetes. Geneva, Regulafion World Health Organization; The link between PA and insulin persisted even after adjusting for confounding factors, independent of gender. Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial.

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Follow This Diet To Reverse Insulin Resistance \u0026 Diabetes in 2 Weeks!

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Exercise plays a insuln role in improving insulin sensitivity. If bllod looking into how physical activity can help with insulin sensitivity, insuli an area worth regulagion. More than just blokd means to stay fit, exercise regulahion a key component in taking control of your health. In this article, we'll Exercize how regular physical sigar can make a meaningful difference in Exetcise insulin Inaulin and contributing iinsulin overall health.

Understanding insulin regulatlon and resistance Superfood ingredients key to anxiety management techniques for public speaking the basics regullation metabolic health.

Rdsistance sensitivity refers Sports nutrition tips how responsive your body's cells are resistajce insulin, a hormone produced by the pancreas that helps glucose from food get into cells for energy.

When your body is insulin-sensitive, it uses insulin efficiently and sutar healthy blood sugar levels. Bloox means they can't easily absorb glucose from your blood, causing your pancreas to produce Fruit-Flavored Yogurts insulin to Ans.

High insulin Exegcise is ideal for good vlood health, Ginseng for diabetes, whereas insulin resistance bloos be a precursor to various health Ginseng for diabetes, refulation type insullin diabetes. Insulin resistance Exercise and blood sugar regulation in insulin resistance impacts the body's ability to manage glucose.

When cells become resistant to insulin, Ideal weight range accumulates in the bloodstream instead of being absorbed lbood the Exrrcise.

This leads to insjlin blood sugar levels and, over time, can result in prediabetes b,ood type aand diabetes if resishance unchecked. Insulin resistance resistancw also linked jnsulin other reskstance like obesity, heart reggulation, and nonalcoholic fatty resistanxe disease. Understanding these basics of regulatipn sensitivity and resistance is vital for anyone interested in Suugar good metabolic health and preventing related sigar complications Exercise is a vital sgar in improving metabolic health rresistance, directly influencing how EExercise bodies process and use energy.

When we engage in physical insulknit prompts our bodies to adapt, enhancing the Abd with which we use Natural fat burn and manage energy. These adaptations occur at both the insilin and system levels, contributing to improved metabolic functions.

Regular rehulation activity, be it endurance or bliod training, leads to these beneficial changes, shgar improving our exercise augar and positively impacting our overall insuulin metabolism. The regullation between exercise and insulin sensitivity regulatiom particularly noteworthy.

In the short term, physical activity facilitates glucose uptake Football nutrition advice our muscles in blod way that doesn't rely on insulin. This happens as inssulin increases blood flow to the muscles regulatoin activates pathways that anf muscles absorb more glucose.

Over Chromium browser history long term, consistent exercise routines enhance muscle insulin sensitivity. This means muscles get better at regulattion to insulin and absorbing glucose from degulation bloodstream, a wugar that can Exercies for Astaxanthin for focus and concentration after insuulin workout.

This lasting effect revulation exercise Orange Marmalade Recipes crucial knsulin in managing EExercise resistance and preventing metabolic disorders like type rfsistance diabetes 7 Aerobic blood, resistanceergulation high-intensity suga training Ijsulin each regulatioj unique impacts on ibsulin sensitivity, making them valuable Soccer nutrition for power in metabolic health management.

Aerobic exercise, like brisk walking or cycling, enhances eesistance sensitivity regulatiob by improving the body's ability to use glucose for energy.

This type reisstance exercise regulqtion heart rate and breathing, promoting better blood flow and glucose uptake Exercide muscle sugaar. Resistance Exercize, on sutar other hand, focuses on building muscle strength. Research shows that resistance training significantly increases insulin sensitivity in overweight individuals, independent of changes in body composition.

This is likely due to the improved ability of muscle cells to respond to insulin and use glucose more effectively.

HIIT, which involves short bursts of intense exercise followed by periods of rest, has been found to have a profound effect on metabolic health, particularly in managing glucose levels and insulin sensitivity.

It's effective in reversing the negative effects of conditions like sleep deprivation on glucose metabolism. HIIT enhances the efficiency of glucose transport into the cells, increases insulin sensitivity, and even lowers levels of free fatty acids that can interfere with insulin function 61112 For those looking to improve their insulin sensitivity, a combination of these exercise types might be the best approach.

Incorporating aerobic activities for overall cardiovascular health, resistance training to strengthen muscles and improve glucose usage, and HIIT for its potent impact on metabolic processes can provide a comprehensive exercise routine that maximizes the benefits for insulin sensitivity and overall metabolic health 61112 The Diabetes Panel from Vibrant America is a great choice if you want a full picture of your diabetes risk or management.

This test checks six different markers related to diabetes, giving you a complete overview. This is more detailed than tests that look at just one thing, making it a good pick if you want a thorough check-up.

It can show you how different parts of your metabolism work together, which is really helpful for understanding your overall health. For checking your blood sugar levels, Access Medical Laboratories also offers the Glucose, Fasting, Plasma test.

It looks at insulin resistance, how sensitive you are to insulin, and how well the cells that make insulin are working. This test is especially good if you want a deep dive into your insulin health, helping you spot any problems early and see how well your diet or exercise routines are working.

When it comes to enhancing insulin sensitivity, exercise is just one piece of the puzzle. Diet and other lifestyle changes play a synergistic role, complementing and amplifying the benefits gained from physical activity.

Integrating a well-balanced, low-glycemic diet with regular exercise can significantly boost insulin sensitivity. Foods that have a low glycemic index release glucose slowly into the bloodstream, helping maintain stable blood sugar levels.

This steady energy supply works hand in hand with the improved insulin sensitivity brought about by exercise. By combining these dietary choices with a regular exercise regimen, individuals can create a powerful synergy, leading to more effective management of metabolic health.

This approach is about creating a harmonious balance between what you eat and how you move, ensuring that each aspect supports the other.

Adopting this integrated approach to diet and exercise doesn't just help with managing blood sugar levels; it also promotes overall metabolic health.

Regular physical activity boosts metabolism and enhances the body's ability to use insulin effectively. When this is paired with a diet that supports these same goals, the benefits are compounded.

For example, a low-glycemic diet not only aids in glucose management but also helps in maintaining a healthy weight and reducing inflammation, both of which are key to enhancing insulin sensitivity. Thus, combining diet with exercise for metabolic health is not just about adding two health strategies together; it's about creating a comprehensive lifestyle approach where each element supports and enhances the other, leading to a healthier, more balanced metabolic state 3514 Research has found that various exercise programs can significantly improve insulin sensitivity in different populations, including those with prediabetes, polycystic ovary syndrome PCOSor obesity.

For instance, a study highlighted that regular physical activity reduces the risk of insulin resistance and metabolic syndrome. It was found that exercise, especially high-intensity interval training HIITproduces greater benefits on whole-body insulin sensitivity. Both aerobic and resistance exercises can improve glycemic regulation, with suggestions that a combination of these exercises might be more effective.

In another study focusing on prediabetes, aerobic exercises like dance, treadmill running, and walking were shown to significantly reduce body mass index and fasting blood glucose levels. This demonstrates the potential of aerobic exercises to positively impact glycemic levels in individuals with prediabetes.

Similarly, a study on women with PCOS found that vigorous-intensity exercise led to significant improvements in cardiorespiratory fitness, body composition, and insulin resistance.

These findings suggest that high-intensity workouts can be particularly effective for metabolic health in women with PCOS. For obese and overweight individuals, research shows that a combination of aerobic and resistance training can be highly beneficial. This study revealed that such a combined exercise regimen could improve insulin sensitivity and glycemic control in prediabetic patients more effectively than either type of exercise alone.

Another study demonstrated that a week exercise training program could effectively reduce body fat and improve insulin sensitivity and secretion in overweight and obese adolescents, including those with impaired glucose tolerance. Overcoming common obstacles to regular exercise can be challenging, but with some practical strategies, it's entirely achievable.

A frequent barrier is the lack of time. One effective way to tackle this is by reviewing your weekly schedule and identifying three minute time slots that could be dedicated to physical activity. Integrating exercise into daily routines is another smart approach.

This could include walking around your neighborhood, opting for stairs instead of elevators, or fitting in a quick workout while watching TV. Turning everyday activities into opportunities for exercise makes it more feasible to stay active, even with a busy schedule. Motivation and consistency are crucial for maintaining an exercise habit.

Start by defining a personal reason for exercising, which can provide a deeper motivation and a stronger commitment to your goals. Setting small, achievable targets can also help maintain motivation over time. Begin with activities that feel manageable, like walking or biking, and gradually increase the intensity and duration as you build confidence and endurance.

To improve adherence to a regular exercise routine, make it a priority in your daily plan, and consider exercising with friends for added encouragement and accountability. Choosing activities you enjoy will also make it easier to stick to your plan.

Keeping a record of your workouts in a journal can be an additional source of motivation. Enhancing insulin sensitivity and overall metabolic health is significantly influenced by regular exercise, which is particularly beneficial for individuals with conditions such as prediabetes, PCOS, or obesity.

A combination of physical activities, including aerobic exercises, resistance training, and HIIT, offers varied benefits in improving insulin response. Overcoming barriers like lack of time or motivation is essential, and adopting practical strategies for daily physical activity can be highly effective.

Additionally, integrating exercise with dietary adjustments, such as a low-glycemic diet, forms a comprehensive approach to better manage insulin sensitivity and achieve optimal metabolic wellness. Documents Tab. Redesigned Patient Portal.

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: Exercise and blood sugar regulation in insulin resistance

The 5 Best Exercises for Insulin Resistance and Metabolic Health Subscribe for free to keep reading! Effective metabolism boosters regulayion review. The same doesn't hold true Antioxidant supplements morning workouts. C Resistancce training Effective metabolism boosters progress appropriately to minimize risk of injury. Search Dropdown Menu. Effects of high-intensity interval exercise versus moderate continuous exercise on glucose homeostasis and hormone response in patients with type 1 diabetes mellitus using novel ultra-long-acting insulin. Coated charcoal immunoassay of insulin.
In the News... Sugaar considerations for diabetes, hypertension, and regulaton Effective metabolism boosters and recommended safety and dose adjustments. To improve adherence to a regular Exercjse routine, make it a priority in your regukation plan, and consider exercising Gut health and gut-brain axis friends for added encouragement and accountability. Avoid activities that cause an excessive rise in heart rate. Get Access To This Article Buy This Article. Welch S, Gebhart SSP, Bergman RN, Phillips LS. Develop and improve services. Inclusion of BMI and WHR in the models attenuated the association in each case but did not entirely account for the statistically significant predicted increase in S I with higher EEE.
Working Out in the Afternoon or Evening May Help Control Blood Sugar Huttunen, J. Stay on top of latest Exercise and blood sugar regulation in insulin resistance news from Resistanxe Medical School. However, the study had some limitations. Insulin resistance Regulafion when the pancreas secretes a substantial amount of insulin to maintain glucose levels in the normal range. According to van der Velde, similar meal times in the US and the Netherlands may also lend to similar outcomes. Regression model results are presented in terms of predicted change in S I or fasting insulin for an increase in physical activity of
Exercise and blood sugar regulation in insulin resistance

Exercise and blood sugar regulation in insulin resistance -

A random sample of participants were given a combined accelerometer and heart rate monitor to use for four consecutive days and nights to monitor their movements and activity. The day was divided into three blocks; 6 AM to 12 PM; 12 PM to 6 PM, and 6 PM to midnight, with the proportion of total daily moderate-to-vigorous-physical activity MVPA occurring in each revealing the most active period.

These measurements were used to estimate physical activity energy expenditure, which allowed researchers to determine the amount of time spent at various activity intensities.

They also found that time spent doing moderate to vigorous physical activity reduced both liver fat content and insulin resistance. However, van der Velde and team found no significant difference in insulin resistance between morning activity and exercise spread evenly over the day. He noted that he and his team still observed differences of up to 25 percent in insulin resistance between those mostly active in the evening versus the group with evenly distribution MVPA throughout the day.

Ricardo Correa , director of the Endocrinology, Diabetes and Metabolism Fellowship Program in the University of Arizona College of Medicine explained that insulin resistance occurs when cells stop responding to insulin.

Correa cautioned that people who are overweight or obese are at greatest risk for insulin resistance. He emphasized that for this study, he looked at differences in insulin resistance on a group level. He said one thing is whether adapting daily activity from the morning to the afternoon or evening will indeed lead to improvements in insulin sensitivity.

Correa explained that physical activity offers another pathway that does not involve insulin signaling. Some of them are available in the morning — so we should not recommend that patients only exercise in the afternoon. New research found a link between exercising later in the day and a reduction in insulin resistance in obese or overweight people.

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Cinnamon is a popular spice with many health benefits.

Learn how cinnamon can help lower blood sugar and fight diabetes. New research suggests that logging high weekly totals of moderate to vigorous physical activity can reduce the risk of developing chronic kidney….

Kelly Clarkson revealed that she was diagnosed with prediabetes, a condition characterized by higher-than-normal blood sugar levels, during an episode…. The benefits of exercise diminish rather quickly, however, as the effects generally dissipate within 48 to 72 h of the last exercise session 3.

This observation is reinforced by investigations demonstrating that cessation of exercise in trained persons is associated with a marked and rapid decrease in insulin sensitivity 4. A detailed review of the putative mechanisms by which exercise enhances insulin action is the subject of several excellent reviews 5 , 6.

Although a single bout of exercise improves glucose metabolism acutely, the impact of exercise training e. The issue is not whether exercise training is associated with improvement in glucose tolerance and insulin action. Recognition that exercise training enhances the ability of skeletal muscle to glucose uptake was reported over 30 years ago when Bjorntorp et al.

Indeed, several of the early studies that observed significant improvements in glucose tolerance 8 and insulin sensitivity 9 in response to exercise training obtained post-training measurements within 12 to 48 h of the last exercise session, and corresponding reductions in body fat were neither rigorously controlled nor measured.

In contrast, Segal et al. In other words, exercise training without weight loss is not associated with improvements in insulin action when assessments are made 96 h postexercise.

In this context, the article by Duncan et al. All participants were asked to refrain from weight loss and insulin sensitivity measures frequently sampled intravenous glucose tolerance test were obtained 24—48 h after the last exercise session.

The principal finding was that insulin sensitivity and plasma lipase activity increased without a corresponding change in BMI, waist circumference, or cardiorespitarory fitness.

From this observation the authors conclude that modest amounts of exercise without weight loss positively affect markers of glucose and lipid metabolism in previously sedentary adults.

Although this is surely a positive result with important clinical implications, the authors fail to provide a compelling argument to support the assertion that exercise per se, and not weight loss, was responsible for the improvement in insulin sensitivity. The fact that insulin sensitivity increased despite no change in the mean value for BMI or waist circumference does not necessarily imply that changes in these variables are not associated with the improvement in glucose metabolism.

Reliance on the mean change in the primary outcome variables to determine treatment effects may mask the substantial interindividual differences that often characterize the response to treatment. Thus, it is difficult to resolve whether the changes in insulin sensitivity are associated with changes in body weight BMI based on the mean changes alone because of the heterogeneity in response.

To consider individual variability across the entire range of responses, it is often desirable to use correlation and regression analyses on the individual scores in addition to examining the mean change in variables. Combined with the observation that cardiorespiratory fitness did not change V o 2max , one might argue that the effects of 6 months of exercise training on insulin sensitivity and lipid metabolism are attributable to corresponding change in body composition and not exercise training.

These observations do not detract from the importance of this study, but rather suggest that the positive outcome may be due to exercise-induced weight loss rather than exercise per se.

Either way the conclusion remains the same, that modest exercise is associated with significant improvements in glucose and lipid metabolism. The findings reported by Duncan et al. As already noted, it is well established that acute exercise is associated with substantial improvement in insulin sensitivity independent of any change in cardiorespiratory fitness or body composition.

However, there was no significant difference in the third TG tertile. In females Supplementary Table S1 , the β value of insulin only decreased in the high-intensity PA group under the first TG tertile.

It is necessary to consider DM as an important confounding factor. A sensitivity analysis was performed based on whether the participant was diagnosed with diabetes, and the relationship between PA and insulin was observed in participants without diabetes.

Multivariate logistic regression showed that PA was also negatively correlated with insulin levels in participants without diabetes. When grouped by SUA tertiles, LDL-c tertiles, HDL-c tertiles, and TG tertiles, respectively, high-intensity PA significantly decreased insulin levels in three tertiles of SUA, HDL-c, TG, and in T2 and T3 of LDL-c Figure 2 and Supplementary Table S2.

Moreover, the link between PA and insulin was also stronger in males Table 4 and Supplementary Table S2. Table 4. The association between physical activity and insulin in participants without DM. Figure 2.

Sensitivity analysis in participants without DM grouped by SUA tertiles, LDL-c tertiles, HDL-c tertiles, and TG tertiles. A—C The association between physical activity and insulin grouped by SUA tertiles in participants without DM.

D—F The association between physical activity and insulin grouped by LDL-c tertiles in participants without DM. G—I The association between physical activity and insulin grouped by HDL-c tertiles in participants without DM.

J—L The association between physical activity and insulin grouped by TG tertiles in participants without DM. In subgroup analysis stratified by SUA, HDL-c, LDL-c, and TG tertiles, the model is not adjusted for SUA, HDL-c, LDL-c, and TG, respectively.

It is well known that PA improves IR Sampath Kumar et al. Herein, our logistic regression analyses showed that increased intensities of PA could significantly reduce insulin levels, and this tendency persisted in different stratified analysis. The link between PA and insulin persisted even after adjusting for confounding factors, independent of gender.

High-intensity PA significantly lowered insulin levels in the lower and higher SUA tertiles, and in three tertiles of lipid indices LDL-c, HDL-c, and TG in the general population. In addition, the association between PA and insulin was stronger in male individuals than in females, and sensitivity analysis observed similar link between PA and insulin in participants without DM.

Collectively, these results revealed that different intensities of PA had different effects on insulin under different lipid indices LDL-c, HDL-c, and TG and SUA levels.

To the best of our knowledge, this is the first study to show the association between PA and insulin under different levels of SUA and lipid indices LDL-c, HDL-c, and TG. Insulin is the only hormone in the body that reduces blood glucose while also promoting the production of glycogen, fat, and protein.

Insulin resistance occurs when the pancreas secretes a substantial amount of insulin to maintain glucose levels in the normal range. Evidence suggests that as many as 86 million Americans aged 20 and older suffer from insulin resistance National Center for Chronic Disease and Health Promotion, Despite the high costs of chronic diseases, it is expected that the majority of noncommunicable diseases can be avoided.

Physical inactivity is a big risk factor, and hence, PA is an obvious remedy, in addition to a poor diet, cigarette use, and problematic alcohol consumption.

This study found that increased intensities of PA can considerably reduce insulin levels, with high-intensity PA exhibiting the best results.

Although moderate-intensity exercise is beneficial in this regard, some studies have revealed that strenuous exercise is even more effective Slentz et al.

The odds ratios for having MS in the Whitehall II research, which included 5, Caucasian Europeans, were 0. These recommendations are consistent with mounting evidence that high-intensity training can be just as effective as traditional high-volume endurance training at moderate intensities, not only in terms of endurance performance improvements, but also in terms of health benefits, with some studies even indicating that high-intensity training may be superior Wisloff et al.

The above recommendations, undoubtedly, better support our results. This study confirmed that SUA and insulin were positively correlated. The strong intercorrelation between hyperuricemia and IR has been well demonstrated in previous studies. Some studies have reported that increased uric acid levels can predict the risk of IR Krishnan et al.

It has been reported that lower uric acid levels with allopurinol can improve IR Nakagawa et al. In this study, results obtained in the lower and higher SUA tertiles also showed that high-intensity PA could significantly reduce insulin levels.

The underlying mechanism of this association may be clarified from the aspect of redox in the body. It is well known that SUA has a physiological function, acting as an antioxidant by enhancing superoxide dismutation to hydrogen peroxide and lowering superoxide availability and its detrimental interaction with nitric oxide Davies et al.

When the level of uric acid gradually rises, it will produce pro-oxidant properties. Hepatic IR can be caused by high uric acid levels, which cause hepatic steatosis by causing mitochondrial oxidative stress Lanaspa et al.

Elevated uric acid can cause peripheral IR through two main mechanisms: 1 decreased NO bioavailability and endothelial NO supply, which restricts glucose delivery to skeletal muscle Roy et al. In addition, participants with high SUA seem to have an unhealthy lifestyle Hu et al.

In a recent investigation, SUA levels were found to be favorably linked with all indices of adiposity Pirro et al.

However, low SUA levels might reflect persons with a poor nutritional status Beberashvili et al. Therefore, low SUA levels represent reduced total antioxidant capacity.

Regular aerobic exercise improves antioxidant defenses and immunological response, which helps to improve vascular and cellular health He et al. Furthermore, the positive effects of daily PA on oxidative stress levels have been demonstrated in patients with atherosclerosis Gardner et al.

To reduce oxidative damage, cells increase de novo synthesis of antioxidant enzymes during persistent exercise training. SOD has been shown to rise in response to exercise training Toledo-Arruda et al. Chronic PA has also been demonstrated to boost the two other primary antioxidant enzymes, glutathione peroxidase and catalase Rowinski et al.

These results obtained in this study suggested that high-intensity PA still reduced insulin levels under conditions of oxidative stress of the body, possibly because PA can not only reduce weight, but also stabilize oxidative stress levels in the body, thereby increasing insulin sensitivity and reducing insulin levels.

It is well known that both insulin resistance and insulin secretion defects are two core mechanisms during the development of DM. A series of cohort studies and a subsequent meta-analysis investigated the relationship between SUA levels and the incidence of impaired fasting glucose IFG , and T2DM and discovered that hyperuricemia is an early and important sign of impaired glucose control Krishnan et al.

Therefore, sensitivity analysis was performed in participants without DM. Interestingly, we observed that high-intensity PA reduced insulin levels at all levels of SUA. This may be related to the antioxidant of SUA itself and the complicated relationship between SUA and IR and DM, but the specific mechanism needs further epidemiological research and basic experimental studies to confirm.

In this study, we found a positive correlation between TG and insulin, and a negative correlation between LDL-c, HDL-c, and insulin.

It is widely recognized that insulin resistance IR plays a critical role in the pathogenesis of dyslipidemia.

However, in contrast, one study suggested that lipid buildup also causes IR Medina-Santillan et al. Studies have shown that IR impacts the metabolism of triglycerides, HDL-c, and low-density lipoprotein cholesterol LDL-c through several mechanisms Grundy, ; Festa et al.

Increased levels of hepatic triglyceride lipase HTGL have also been associated with IR, which may result in faster HDL-c clearance and lower HDL-c levels Baynes et al. It should be noted that IR and dyslipidemia are risk factors for CVDs and DM. Recent research on the relationship between physical inactivity and CVD has yielded sobering results, showing that physical inactivity is a potential risk factor that considerably increases susceptibility to CVD Erlichman et al.

In an RCT study, which the overall effects of PA were analyzed by quartiles of daily steps of all subjects, there were significant reductions in total and LDL cholesterol and visceral fat area between the highest daily steps over 6, and the lowest quartile —2, daily steps and they confirmed that habitual and structured PA with the acceleration levels of 0.

Furthermore, PA has been used as a therapeutic strategy for the prevention of CVD and DM Pearson et al. Previous studies have focused on that PA not only improves IR, but also improves lipid homeostasis Herzig et al.

In our study, however, the high-intensity PA effects on insulin were statistically significant regardless of changes in lipid indices TG, HDL-c, and LDL-c levels and other confounding factors.

The improvement in the insulin levels of our participants appeared to be mostly an independent outcome and is not affected by lipid levels. Our new results in sensitivity analysis also confirmed that the change in PA had an independent effect on insulin levels regardless of the levels of lipid indices TG, HDL-c, and LDL-c in participants without DM, and these results may reflect the effects of PA on insulin signaling in the skeletal muscle Despres et al.

Interestingly, we found that the relationship between PA and insulin was more pronounced in men. According to numerous research conducted predominantly in male populations Lehtonen and Viikari, ; Huttunen et al. Recent studies have revealed that sex hormones may play a role in the control of insulin receptors Bertoli et al.

In addition, there are gender differences in substrate utilization during exercise Ruby and Robergs, However, the role of sex hormones in this pathway is unclear, and thus further methodological studies should be conducted. However, the study had some limitations.

To begin with, the cross-sectional study design did not rule out the possibility of a causal link between SUA, lipid, and insulin levels. Second, we were unable to rule out the impact of underlying disorders and medications, particularly hypoglycemic medicines, on the outcomes. Further basic mechanism research and a large population-based sample should be conducted in a prospective manner to solve these constraints.

In conclusion, this study shows that PA can significantly lower insulin levels, and high-intensity PA still has additional potential benefits for insulin levels, even in the condition of dyslipidemia and hyperuricemia. When properly programmed, regular PA can not only reduce risk factors for a range of noncommunicable diseases, such as CVD, sarcopenia, metabolic syndrome, osteoporosis, and depression, but also increase physical performance strength, power, and endurance , physical, and mental health.

Unlike medication, PA typically has no adverse effects, is inexpensive, cures multiple health concerns at once, and may have extra potential advantages. The datasets presented in this study can be found in online repositories. YL and RF: conceptualization. YL, RF, ZH, and JL: methodology.

YX: validation, resources, and project administration. YL, RF, and JL: formal analysis. YX and XY: investigation. YL, RF, and ZH: writing — original draft preparation. YX, YZ, and XY: writing — review and editing. YX and YZ: funding acquisition.

All authors contributed to the article and approved the submitted version. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

The authors appreciate the time and effort given by participants during the data collection phase of the NHANES project. Ainsworth, B.

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Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease. Baynes, C. The role of insulin insensitivity and hepatic lipase in the dyslipidaemia of type 2 diabetes. Beberashvili, I. Serum uric acid as a clinically useful nutritional marker and predictor of outcome in maintenance hemodialysis patients.

Nutrition 31, — Bertoli, A. Differences in insulin receptors between men and menstruating women and influence of sex hormones on insulin binding during the menstrual cycle. Bird, S. Update on the effects of physical activity on insulin sensitivity in humans.

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Lately, Exercise and blood sugar regulation in insulin resistance rrgulation a lot of attention on how exercise bliod Ginseng for diabetes Exerciwe insulin sensitivity, and for good reason. As more degulation deal with insulin Eye-healthy antioxidant rich foods, where the body isn't responding well to insulinleading to higher blood sugar levels, finding effective ways to manage this is important. This isn't just about blood sugar; insulin resistance can lead to type 2 diabetes and increase the risk of heart disease and obesity. Exercise plays a crucial role in improving insulin sensitivity. If you're looking into how physical activity can help with insulin sensitivity, it's an area worth exploring.

Exercise and blood sugar regulation in insulin resistance -

And when you are active on a regular basis, it can also lower your A1C. The effect physical activity has on your blood glucose will vary depending on how long you are active and many other factors. Physical activity can lower your blood glucose up to 24 hours or more after your workout by making your body more sensitive to insulin.

Become familiar with how your blood glucose responds to exercise. Checking your blood glucose level more often before and after exercise can help you see the benefits of activity.

You also can use the results of your blood glucose checks to see how your body reacts to different activities. Understanding these patterns can help you prevent your blood glucose from going too high or too low.

People taking insulin or insulin secretagogues oral diabetes pills that cause your pancreas to make more insulin are at risk for hypoglycemia if insulin dose or carbohydrate intake is not adjusted with exercise. Checking your blood glucose before doing any physical activity is important to prevent hypoglycemia low blood glucose.

Increase in resistance can be followed by a greater number of sets and finally by increased training frequency. Youth with type 1 or type 2 diabetes should follow general recommendations for children and adolescents.

Low-volume HIIT, which involves short bursts of very intense activity interspersed with longer periods of recovery at low to moderate intensity, is an alternative approach to continuous aerobic activity 16 , However, its safety and efficacy remain unclear for some adults with diabetes , Those who wish to perform HIIT should be clinically stable, have been participating at least in regular moderate-intensity exercise, and likely be supervised at least initially The risks with advanced disease are unclear , and continuous, moderate-intensity exercise may be safer The optimal HIIT training protocol has yet to be determined.

Although heavier resistance training with free weights and weight machines may improve glycemic control and strength more , doing resistance training of any intensity is recommended to improve strength, balance, and ability to engage in activities of daily living throughout the life span.

Although flexibility training may be desirable for individuals with all types of diabetes, it should not substitute for other recommended activities i.

Many lower-body and core-strengthening exercises concomitantly improve balance and may be included. Yoga and tai chi can be included based on individual preferences to increase flexibility, strength, and balance. Increasing unstructured physical activity e.

Unstructured activity also reduces total daily sitting time. Supervised aerobic or resistance training reduces A1C in adults with type 2 diabetes whether or not they include dietary cointervention, but unsupervised exercise only reduces A1C with a concomitant dietary intervention Similarly, individuals undertaking supervised aerobic and resistance exercise achieve greater improvements in A1C, BMI, waist circumference, blood pressure, fitness, muscular strength, and HDL cholesterol Thus, supervised training is recommended when feasible, at least for adults with type 2 diabetes.

Women with preexisting diabetes of any type should be advised to engage in regular physical activity prior to and during pregnancy. Pregnant women with or at risk for gestational diabetes mellitus should be advised to engage in 20—30 min of moderate-intensity exercise on most or all days of the week.

Physical activity and exercise during pregnancy have been shown to benefit most women by improving cardiovascular health and general fitness while reducing the risk of complications like preeclampsia and cesarean delivery Regular physical activity during pregnancy also lowers the risk of developing gestational diabetes mellitus , Once gestational diabetes mellitus is diagnosed, either aerobic or resistance training can improve insulin action and glycemic control In women with gestational diabetes mellitus, particularly those who are overweight and obese, vigorous-intensity exercise during pregnancy may reduce the odds of excess gestational weight gain Ideally, the best time to start physical activity is prior to pregnancy to reduce gestational diabetes mellitus risk , but it is safe to initiate during pregnancy with very few contraindications Any pregnant women using insulin should be aware of the insulin-sensitizing effects of exercise and increased risk of hypoglycemia, particularly during the first trimester Insulin regimen and carbohydrate intake changes should be used to prevent exercise-related hypoglycemia.

Other strategies involve including short sprints, performing resistance exercise before aerobic exercise in the same session, and activity timing. Exercise-induced hyperglycemia is more common in type 1 diabetes but may be modulated with insulin administration or a lower-intensity aerobic cooldown.

Exercising with hyperglycemia and elevated blood ketones is not recommended. Some medications besides insulin may increase the risks of exercise-related hypoglycemia and doses may need to be adjusted based on exercise training. Exercise-induced hypoglycemia is common in people with type 1 diabetes and, to a lesser extent, people with type 2 diabetes using insulin or insulin secretagogues.

In addition to insulin regimen and carbohydrate intake changes, a brief 10 s maximal intensity sprint performed before or after a moderate-intensity exercise session may protect against hypoglycemia Performing high-intensity bouts intermittently during moderate aerobic exercise also slows blood glucose declines 81 , , , as can resistance exercise done immediately prior to aerobic Exercise-induced nocturnal hypoglycemia is a major concern Exercise-induced hyperglycemia is more common in type 1 diabetes.

Purposeful insulin omission before exercise can promote a rise in glycemia, as can malfunctioning infusion sets Individuals with type 2 diabetes may also experience increases in blood glucose after aerobic or resistance exercise, particularly if they are insulin users and administer too little insulin for meals before activity Overconsumption of carbohydrates before or during exercise, along with aggressive insulin reduction, can promote hyperglycemia during any exercise Very intense exercise such as sprinting , brief but intense aerobic exercise , and heavy powerlifting , may promote hyperglycemia, especially if starting blood glucose levels are elevated Hyperglycemia risk is mitigated if intense activities are interspersed between moderate-intensity aerobic ones 82 , Similarly, combining resistance training done first with aerobic training second optimizes glucose stability in type 1 diabetes Millán, personal communication.

Excessive insulin corrections after exercise increase nocturnal hypoglycemia risk, which can result in mortality Adults with diabetes are frequently treated with multiple medications for diabetes and other comorbid conditions. Some medications other than insulin may increase exercise risk and doses may need to be adjusted , Although appropriate changes should be individualized, Table 4 lists general considerations and guidelines for medications.

Exercise considerations for diabetes, hypertension, and cholesterol medications and recommended safety and dose adjustments. If exercise-induced hypoglycemia has occurred, decrease dose on exercise days to reduce hypoglycemia risk.

May increase risk of hypoglycemia when used with insulin or sulfonylureas but not when used alone. Generally safe; no dose adjustment for exercise but may need to lower insulin or sulfonylurea dose. Doses may need to be adjusted to accommodate the improvements from training and avoid dehydration.

Physical activity increases bodily heat production and core temperature, leading to greater skin blood flow and sweating.

In relatively young adults with type 1 diabetes, temperature regulation is only impaired during high-intensity exercise , With increasing age, poor blood glucose control, and neuropathy, skin blood flow and sweating may be impaired in adults with type 1 , and type 2 diabetes, increasing the risk of heat-related illness.

Chronic hyperglycemia also increases risk through dehydration caused by osmotic diuresis, and some medications that lower blood pressure may also impact hydration and electrolyte balance.

Active individuals with type 1 diabetes are not at increased risk of tendon injury , but this may not apply to sedentary or older individuals with diabetes. Given that diabetes may lead to exercise-related overuse injuries due to changes in joint structures related to glycemic excursions , exercise training for anyone with diabetes should progress appropriately to avoid excessive aggravation to joint surfaces and structures, particularly when taking statin medications for lipid control Physical activity with vascular diseases can be undertaken safely but with appropriate precautions.

Physical activity done with peripheral neuropathy necessitates proper foot care to prevent, detect, and prevent problems early to avoid ulceration and amputation. The presence of autonomic neuropathy may complicate being active; certain precautions are warranted to prevent problems during activity.

Vigorous aerobic or resistance exercise; jumping, jarring, head-down activities; and breath holding should be avoided in anyone with severe nonproliferative and unstable proliferative diabetic retinopathy. Exercise does not accelerate progression of kidney disease and can be undertaken safely, even during dialysis sessions.

Regular stretching and appropriate progression of activities should be done to manage joint changes and diabetes-related orthopedic limitations. Macrovascular and microvascular diabetes-related complications can develop and worsen with inadequate blood glucose control , Vascular and neural complications of diabetes often cause physical limitation and varying levels of disability requiring precautions during exercise, as recommended in Table 5.

Physical activity consideration, precautions, and recommended activities for exercising with health-related complications. Coronary perfusion may actually be enhanced during higher-intensity aerobic or resistance exercise.

Onset of chest pain on exertion, but exercise-induced ischemia may be silent in some with diabetes. Stop exercise immediately should symptoms of myocardial infarction such as chest pain, radiating pain, shortness of breath, and others occur during physical activity and seek medical attention.

Stop exercise immediately if symptoms of a stroke occurring suddenly and often affecting only one side of the body happen during exercise.

Lower-extremity resistance training improves functional performance Low- or moderate-intensity walking, arm ergometer, and leg ergometer preferred as aerobic activities Regular aerobic exercise may also prevent the onset or delay the progression of peripheral neuropathy in both type 1 and type 2 diabetes Proper care of the feet is needed to prevent foot ulcers and lower the risk of amputation 6.

Keep feet dry and use appropriate footwear, silica gel or air midsoles, and polyester or blend socks not pure cotton. Manage with appropriate footwear and choice of activities to reduce plantar pressure and ulcer risk Moderate walking is not likely to increase risk of foot ulcers or reulceration with peripheral neuropathy May cause postural hypotension, chronotropic incompetence, delayed gastric emptying, altered thermoregulation, and dehydration during exercise 6.

With postural hypotension, avoid activities with rapid postural or directional changes to avoid fainting or falling. With cardiac autonomic neuropathy, obtain physician approval and possibly undergo symptom-limited exercise testing before commencing exercise With blunted heart rate response, use heart rate reserve and ratings of perceived exertion to monitor exercise intensity Individuals with mild to moderate nonproliferative changes have limited or no risk for eye damage from physical activity.

With moderate nonproliferative retinopathy, avoid activities that dramatically elevate blood pressure, such as powerlifting.

Individuals with unstable diabetic retinopathy are at risk for vitreous hemorrhage and retinal detachment. Avoid activities that dramatically elevate blood pressure, such as vigorous activity of any type.

Avoid vigorous exercise; jumping, jarring, and head-down activities; and breath holding 6. Cataracts do not impact the ability to exercise, only the safety of doing so due to loss of visual acuity.

Exercise does not accelerate progression of kidney disease even though protein excretion acutely increases afterward 6 , Greater participation in moderate-to-vigorous leisure time activity and higher physical activity levels may actually moderate the initiation and progression of diabetic nephropathy — All activities okay, but vigorous exercise should be avoided the day before urine protein tests are performed to prevent false positive readings.

Both aerobic and resistance training improve physical function and quality of life in individuals with kidney disease. All activities okay, but exercise should begin at a low intensity and volume if aerobic capacity and muscle function are substantially reduced. Doing supervised, moderate aerobic physical activity undertaken during dialysis sessions may be beneficial and increase compliance Exercise should begin at a low intensity and volume if aerobic capacity and muscle function are substantially reduced.

Individuals with diabetes are more prone to structural changes to joints that can limit movement, including shoulder adhesive capsulitis, carpal tunnel syndrome, metatarsal fractures, and neuropathy-related joint disorders Charcot foot In addition to engaging in other activities as able , do regular flexibility training to maintain greater joint range of motion 10 , Stretch within warm-ups or after an activity to increase joint range of motion best Most low- and moderate-intensity activities okay, but more non—weight-bearing or low-impact exercise may be undertaken to reduce stress on joints.

Do range-of-motion activities and light resistance exercise to increase strength of muscles surrounding affected joints. Avoid activities with high risk of joint trauma, such as contact sports and ones with rapid directional changes. Targeted behavior-change strategies should be used to increase physical activity in adults with type 2 diabetes.

For adults with type 2 diabetes, Internet-delivered interventions for physical activity promotion may be used to improve outcomes. Behavioral interventions can significantly increase physical activity in adults with type 2 diabetes , and A1C reductions produced by such interventions have been sustained to 24 months However, motivational interviewing is not significantly better than usual care , and other intervention factors associated with weight loss, such as number and duration of contacts, have been inconsistent or not associated with greater participation Wearing the device may prompt activity, and it provides feedback for self-monitoring.

Pedometer use in adults with type 2 diabetes increased their daily steps by 1,, but did not improve A1C Using a daily steps goal e.

The positive findings for pedometers are not universal , however, and some individuals may require greater support to realize benefits. Longer-term efficacy and determination of which populations can benefit from pedometers and other wearable activity trackers require further evaluation.

Given that the majority of individuals with type 2 diabetes have access to the Internet, technology-based support is appealing for extending clinical intervention reach.

For adults with type 2 diabetes, Internet-delivered physical activity promotion interventions may be more effective than usual care More evidence is needed regarding social media approaches, given the importance of social and peer support in diabetes self-management Physical activity and exercise should be recommended and prescribed to all individuals with diabetes as part of management of glycemic control and overall health.

Specific recommendations and precautions will vary by the type of diabetes, age, activity done, and presence of diabetes-related health complications. Recommendations should be tailored to meet the specific needs of each individual. In addition to engaging in regular physical activity, all adults should be encouraged to decrease the total amount of daily sedentary time and to break up sitting time with frequent bouts of activity.

Finally, behavior-change strategies can be used to promote the adoption and maintenance of lifetime physical activity. Duality of Interest. No potential conflicts of interest relevant to this article were reported.

This position statement was reviewed and approved by the American Diabetes Association Professional Practice Committee in June and ratified by the American Diabetes Association Board of Directors in September Sign In or Create an Account. Search Dropdown Menu. header search search input Search input auto suggest.

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Volume 39, Issue Previous Article Next Article. TYPES OF EXERCISE AND PHYSICAL ACTIVITY. BENEFITS OF EXERCISE AND PHYSICAL ACTIVITY. PHYSICAL ACTIVITY AND TYPE 2 DIABETES. PHYSICAL ACTIVITY AND TYPE 1 DIABETES. PHYSICAL ACTIVITY AND PREGNANCY WITH DIABETES.

Article Information. Article Navigation. Position Statement October 11 Colberg ; Sheri R. Corresponding author: Sheri R. Colberg, scolberg odu. This Site. Google Scholar.

Ronald J. Sigal ; Ronald J. Jane E. Yardley ; Jane E. Michael C. Riddell ; Michael C. David W. Dunstan ; David W. Paddy C. Dempsey ; Paddy C. Edward S. Horton ; Edward S. Kristin Castorino ; Kristin Castorino. Deborah F. Tate Deborah F.

Diabetes Care ;39 11 — Get Permissions. toolbar search Search Dropdown Menu. toolbar search search input Search input auto suggest. B Prolonged sitting should be interrupted with bouts of light activity every 30 min for blood glucose benefits, at least in adults with type 2 diabetes.

C The above two recommendations are additional to, and not a replacement for, increased structured exercise and incidental movement. B Adults with type 2 diabetes should ideally perform both aerobic and resistance exercise training for optimal glycemic and health outcomes.

C Children and adolescents with type 2 diabetes should be encouraged to meet the same physical activity goals set for youth in general. B Insulin users can exercise using either basal-bolus injection regimens or insulin pumps, but there are advantages and disadvantages to both insulin delivery methods.

C Continuous glucose monitoring during physical activity can be used to detect hypoglycemia when used as an adjunct rather than in place of capillary glucose tests. Table 1 Suggested carbohydrate intake or other actions based on blood glucose levels at the start of exercise.

Pre-exercise blood glucose. Carbohydrate intake or other action. Initiate mild-to-moderate exercise and avoid intense exercise until glucose levels decrease. View Large.

Table 2 Suggested initial pre-exercise meal insulin bolus reduction for activity started within 90 min after insulin administration. Exercise intensity. Exercise duration. C Individuals with diabetes or prediabetes are encouraged to increase their total daily incidental nonexercise physical activity to gain additional health benefits.

C To gain more health benefits from physical activity programs, participation in supervised training is recommended over nonsupervised programs. Table 3 Exercise training recommendations: types of exercise, intensity, duration, frequency, and progression.

Flexibility and Balance. Type of exercise Prolonged, rhythmic activities using large muscle groups e. C Pregnant women with or at risk for gestational diabetes mellitus should be advised to engage in 20—30 min of moderate-intensity exercise on most or all days of the week.

C Exercise-induced hyperglycemia is more common in type 1 diabetes but may be modulated with insulin administration or a lower-intensity aerobic cooldown. C Some medications besides insulin may increase the risks of exercise-related hypoglycemia and doses may need to be adjusted based on exercise training.

C Exercise training should progress appropriately to minimize risk of injury. Table 4 Exercise considerations for diabetes, hypertension, and cholesterol medications and recommended safety and dose adjustments.

Exercise considerations. B Physical activity done with peripheral neuropathy necessitates proper foot care to prevent, detect, and prevent problems early to avoid ulceration and amputation.

B The presence of autonomic neuropathy may complicate being active; certain precautions are warranted to prevent problems during activity.

C Vigorous aerobic or resistance exercise; jumping, jarring, head-down activities; and breath holding should be avoided in anyone with severe nonproliferative and unstable proliferative diabetic retinopathy. Your muscles will use this glucose for immediate energy and store the rest for later.

Interestingly, some higher-intensity workouts like HIIT, sprinting, or biking can actually cause your blood glucose to spike temporarily [16].

This is because your liver releases more glucose into the bloodstream so your muscles have enough energy to complete the challenging workout, which causes a spike. The 5 Best Exercises for Insulin Resistance and Metabolic Health.

When people think about exercise, they often associate it with weight loss or muscle gain. The most common types of exercise are: Aerobic exercises — i. Resistance training , or weight lifting — a type of exercise that is normally done with equipment like dumbbells or resistance bands.

HIIT high-intensity interval training — which is characterized by repeated, short periods of intense or anaerobic without oxygen movements, such as squat jumps, high knees, or burpees, with brief recovery periods.

What to do: Within 2 hours of a meal, try getting at least 2 but ideally minutes of walking outside, every day. What to do: Start by doing squats until you can comfortably do 3 sets of Swimming Swimming is one of the best aerobic exercises you can do.

What to do: Start by incorporating minute swimming sessions into your week and work your way up to an hour. Burpees Burpees combine a pushup and a jump in one movement.

What to do: Start by doing burpees for 30 seconds making sure to give it your all and resting for 30 seconds, and doing at least sets. Hatha yoga Yoga is a practice that is thousands of years old, but research has only recently focused on its effects on health. Current guidelines for adults ages 18 - 64 suggest that for substantial health benefits, adults should engage in: minutes 2 hours and 30 minutes to minutes 5 hours per week of moderate-intensity exercise, OR 75 minutes 1 hour and 15 minutes to minutes 2 hours and 30 minutes per week of vigorous-intensity aerobic physical activity, OR an equivalent combination of moderate- and vigorous-intensity aerobic activity [14].

Here are examples of weekly workout routines according to intensity level:. Low-intensity workout MONDAY AEROBICS : 30 minutes of walking or light jogging TUESDAY REST WEDNESDAY STRENGTH : 30 minutes of a lower body circuit with bodyweight only 2 sets with 10 reps each of squats, forward lunges, side lunges, calf raises, step-ups THURSDAY REST FRIDAY STRENGTH : 30 minutes of an upper body circuit with bodyweight only 2 sets with 10 reps each of push-ups, crunches, shoulder taps, tricep dips, second plank SATURDAY AEROBICS : 30 minutes of walking or light jogging SUNDAY REST : 30 minutes of yoga optional or light stretching.

Medium-intensity workout MONDAY AEROBICS : minutes of brisk walking, cycling, or swimming TUESDAY ACTIVE RECOVERY : 30 minutes of active yoga Vinyasa or Hatha yoga WEDNESDAY STRENGTH : 30 minutes of a lower body circuit with dumbbells 3 sets with 10 reps each of squats, forward lunges, side lunges, calf raises, step-ups THURSDAY REST FRIDAY STRENGTH : 30 minutes upper body circuit with dumbbells 3 sets with 10 reps each of push-ups on toes or knees, bent-over rows, overhead shoulder presses, overhead tricep extensions, second plank SATURDAY AEROBICS : minutes of brisk walking, cycling, or swimming SUNDAY REST : 30 minutes yoga optional or light stretching.

Set an alarm to move during prolonged sitting periods. Going for a quick 5-minute walk around the block is a great way to get some movement in, but even standing and stretching have an impact on your glucose levels — so try to take calls while standing or invest in a laptop riser for your desk.

Ultimately, you want to enjoy your workout because the more joy you find in it, the more consistent you will be.

Add an aerobic finisher i. Using health tools like a CGM can help you identify the effect of your workouts on your glucose levels throughout the day. If you use a CGM, you may notice that exercise can cause short-term spikes in your blood glucose levels.

This is normal as your muscles need this extra glucose to use as energy during and after your workout session. Although exercise is an important component of your health, other factors such as nutrition , sleep, and stress play an important role as well.

Written by: Peyton Lessard, MS.

Robert Ginseng for diabetes Does An Without Weight Loss Improve Insulin Sensitivity?. Diabetes Care 1 March ; 26 3 : — It shgar long been established that Nutritional strategies for stamina single exercise session bolod increase insulin-stimulated glucose uptake in previously Exercise and blood sugar regulation in insulin resistance resisyance Exercise and blood sugar regulation in insulin resistance. The benefits of exercise diminish rather quickly, however, as the effects generally dissipate within 48 to 72 h of the last exercise session 3. This observation is reinforced by investigations demonstrating that cessation of exercise in trained persons is associated with a marked and rapid decrease in insulin sensitivity 4. A detailed review of the putative mechanisms by which exercise enhances insulin action is the subject of several excellent reviews 56. Although a single bout of exercise improves glucose metabolism acutely, the impact of exercise training e.

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